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Bovine Metabolome Database



Showing metabocard for L-Glutamic acid (BMDB00148)

Legend: metabolite field enzyme field

Version 1.0
Creation Date 2005-11-16 15:48:42
Update Date 2009-07-08 14:23:27
Accession Number BMDB00148
Common Name L-Glutamic acid
Description Glutamic acid (Glu), also referred to as glutamate (the anion), is one of the 20 proteinogenic amino acids. It is not among the essential amino acids. Glutamate is a key molecule in cellular metabolism. In humans, dietary proteins are broken down by digestion into amino acids, which serves as metabolic fuel or other functional roles in the body. Glutamate is the most abundant fast excitatory neurotransmitter in the mammalian nervous system. At chemical synapses, glutamate is stored in vesicles. Nerve impulses trigger release of glutamate from the pre-synaptic cell. In the opposing post-synaptic cell, glutamate receptors, such as the NMDA receptor, bind glutamate and are activated. Because of its role in synaptic plasticity, it is believed that glutamic acid is involved in cognitive functions like learning and memory in the brain. Glutamate transporters are found in neuronal and glial membranes. They rapidly remove glutamate from the extracellular space. In brain injury or disease, they can work in reverse and excess glutamate can accumulate outside cells. This process causes calcium ions to enter cells via NMDA receptor channels, leading to neuronal damage and eventual cell death, and is called excitotoxicity. The mechanisms of cell death include: * Damage to mitochondria from excessively high intracellular Ca2+. * Glu/Ca2+-mediated promotion of transcription factors for pro-apoptotic genes, or downregulation of transcription factors for anti-apoptotic genes. Excitotoxicity due to glutamate occurs as part of the ischemic cascade and is associated with stroke and diseases like amyotrophic lateral sclerosis, lathyrism, and Alzheimer's disease. glutamic acid has been implicated in epileptic seizures. Microinjection of glutamic acid into neurons produces spontaneous depolarization around one second apart, and this firing pattern is similar to what is known as paroxysmal depolarizing shift in epileptic attacks. This change in the resting membrane potential at seizure foci could cause spontaneous opening of voltage activated calcium channels, leading to glutamic acid release and further depolarization. (http://en.wikipedia.org/wiki/Glutamic_acid)
Synonyms
  1. (2S)-2-Aminopentanedioate
  2. (2S)-2-Aminopentanedioic acid
  3. (S)-(+)-Glutamate
  4. (S)-(+)-Glutamic acid
  5. (S)-2-Aminopentanedioate
  6. (S)-2-Aminopentanedioic acid
  7. (S)-Glutamate
  8. (S)-Glutamic acid
  9. 1-Aminopropane-1,3-dicarboxylate
  10. 1-Aminopropane-1,3-dicarboxylic acid
  11. 1-amino-propane-1,3-dicarboxylate
  12. 1-amino-propane-1,3-dicarboxylic acid
  13. 2-Aminoglutarate
  14. 2-Aminoglutaric acid
  15. 2-Aminopentanedioate
  16. 2-Aminopentanedioic acid
  17. Aciglut
  18. E
  19. Glusate
  20. Glutacid
  21. Glutamicol
  22. Glutamidex
  23. Glutaminate
  24. Glutaminic acid
  25. Glutaminol
  26. Glutaton
  27. L-(+)-Glutamate
  28. L-(+)-Glutamic acid
  29. L-Glutamate
  30. L-Glutaminate
  31. L-Glutaminic acid
  32. L-a-Aminoglutarate
  33. L-a-Aminoglutaric acid
  34. L-glu
  35. a-Aminoglutarate
  36. a-Aminoglutaric acid
  37. a-Glutamate
  38. a-Glutamic acid
  39. aminoglutarate
  40. aminoglutaric acid
  41. glt
  42. glu
  43. glut
  44. L-alpha-Aminoglutarate
  45. L-alpha-Aminoglutaric acid
  46. alpha-Aminoglutarate
  47. alpha-Aminoglutaric acid
  48. alpha-Glutamate
  49. alpha-Glutamic acid
Chemical IUPAC Name 2-aminopentanedioic acid
Chemical Formula C5H9NO4
Chemical Structure Structure
Chemical Taxonomy
Kingdom
  • Organic
Super Class
  • Amino acids and Amino Acid conjugates
Class
  • Amino Acids
Sub Class
  • NA
Family
  • Mammalian_Metabolite
Species
  • primary amine; primary aliphatic amine (alkylamine); carboxylic acid; alpha-aminoacid
Biofunction
  • Component of Alanine and aspartate metabolism; Component of Aminoacyl-tRNA biosynthesis; Component of Aminosugars metabolism; Component of Arginine and proline metabolism; Component of beta-Alanine metabolism; Component of Butanoate metabolism; Component of Cyanoamino acid metabolism; Component of Cysteine metabolism; Component of D-Glutamine and D-glutamate metabolism; Component of Folate biosynthesis; Component of Glutamate metabolism; Component of Glutathione metabolism; Component of Glycine, serine and threonine metabolism; Component of Lysine biosynthesis; Component of Nitrogen metabolism; Component of Novobiocin biosynthesis; Component of Pantothenate and CoA biosynthesis; Component of Peptidoglycan biosynthesis; Component of Phenylalanine metabolism; Component of Phenylalanine, tyrosine and tryptophan biosynthesis; Component of Porphyrin and chlorophyll metabolism; Component of Prostaglandin and leukotriene metabolism; Component of Purine metabolism; Component of Pyrimidine metabolism; Component of Selenoamino acid metabolism; Component of Taurine and hypotaurine metabolism; Component of Tyrosine metabolism; Component of Valine, leucine and isoleucine biosynthesis; Component of Vitamin B6 metabolism
Application
Source
  • Endogenous
Average Molecular Weight 147.129
Monoisotopic Molecular Weight 147.053162
Isomeric SMILES N[C@@H](CCC(O)=O)C(O)=O
Canonical SMILES NC(CCC(O)=O)C(O)=O
KEGG Compound ID C00025 Link Image
BioCyc ID GLT Link Image
BiGG ID 33561 Link Image
Wikipedia Link E Link Image
METLIN ID 5174 Link Image
PubChem Compound 33032 Link Image
PubChem Substance 7847075 Link Image
ChEBI ID 16015 Link Image
CAS Registry Number 56-86-0
InChI Identifier InChI=1/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
Synthesis Reference Horner, L.; Gross, A. Tertiary phosphines. IV. Use of phosphine imines in causing the introduction of primary amino groups. Ann. (1955), 591 117-34.
Melting Point (Experimental) Not Available
Experimental Water Solubility 8.57 mg/mL [BULL,HB et al. (1978)] Source: PhysProp
Predicted Water Solubility 80.600006 mg/mL [Predicted by ALOGPS] Calculated using ALOGPS
Physiological Charge -1
State Solid
Experimental LogP/Hydrophobicity -3.69 [HANSCH,C ET AL. (1995)] Source: PhysProp
Predicted LogP/Hydrophobicity -3.54 [Predicted by ALOGPS]; -3.3 [Predicted by PubChem via XLOGP] Calculated using ALOGPS
Material Safety Data Sheet (MSDS)
MOL File Show
SDF File Show
PDB File Show
2D Structure
3D Structure
Experimental PDB ID 1BGV Link Image
Experimental PDB File Show
Experimental PDB Structure
Experimental 1H NMR Spectrum Download Spectrum
Download FID (Varian)
Show Experimental Conditions Link Image
Experimental 13C NMR Spectrum Download Spectrum
Download FID (Bruker)
Show Experimental Conditions Link Image
Experimental 13C HSQC Spectrum Download Spectrum
Download FID (Bruker)
Show Experimental Conditions Link Image
Predicted 1H NMR Spectrum Show Image
Show Peaklist
Predicted 13C NMR Spectrum Show Image
Show Peaklist
Mass Spectrum
Low Energy
Download File
Show Experimental Conditions Link Image
Medium Energy
Download File
Show Experimental Conditions Link Image
High Energy
Download File
Show Experimental Conditions Link Image
Simplified TOCSY Spectrum Show Image
Show Peaklist
BMRB Spectrum Show Image
Show Peaklist
Cellular Location
  • Cytoplasm (Predicted from LogP)
  • endoplasmic reticulum
  • Extracellular
  • lysosome
  • mitochondria
Biofluid Location
  • Blood
  • Breast_Milk
Tissue Location
Tissue References
Adipose Tissue
Adrenal Medulla
Epidermis
Fibroblasts
Intestine
Kidney
Muscle
Myelin
Nerve Cells
Neuron
Pancreas
Placenta
Platelet
Skeletal Muscle
Spleen
Stratum Corneum
Concentrations (Normal)
Biofluid Blood
Value 299.1 uM
Age N/A
Sex Both
Condition Normal
Comments Not Available
References
Biofluid Breast_Milk
Value 44 - 693 uM
Age N/A
Sex N/A
Condition Normal
Comments Raw. skim.
References
Biofluid Breast_Milk
Value 47373.393 uM
Age N/A
Sex N/A
Condition Normal
Comments Milk, Skim.
References
Biofluid Breast_Milk
Value 54781.858 uM
Age N/A
Sex N/A
Condition Normal
Comments Milk, fluid, partly skimmed, 1% milkfat.
References
Biofluid Breast_Milk
Value 54577.955 uM
Age N/A
Sex N/A
Condition Normal
Comments Milk, fluid, partly skimmed, 2% milkfat.
References
Biofluid Breast_Milk
Value 44450.788 uM
Age N/A
Sex N/A
Condition Normal
Comments Pasteurized. Milk, whole, pasteurized, homogenized, 3.3% milkfat.
References
Biofluid Breast_Milk
Value 48121.0366 uM
Age N/A
Sex N/A
Condition Normal
Comments Milk, fluid, whole, producer, 3.7% milkfat.
References
Biofluid Breast_Milk
Value 272 +/- 70 uM
Age N/A
Sex N/A
Condition Normal
Comments Quantified by NMR in 2% milk
References
Biofluid Breast_Milk
Value 243 +/- 65 uM
Age N/A
Sex N/A
Condition Normal
Comments Quantified by NMR in skim milk
References
Biofluid Breast_Milk
Value 235 +/- 44 uM
Age N/A
Sex N/A
Condition Normal
Comments Quantified by NMR in 1% milk
References
Biofluid Breast_Milk
Value 287 +/- 22 uM
Age N/A
Sex N/A
Condition Normal
Comments Quantified by NMR in 3.25% milk
References
Biofluid Breast_Milk
Value 277 +/- 11 uM
Age N/A
Sex N/A
Condition Normal
Comments Skim milk
References
Biofluid Breast_Milk
Value 242 +/- 11 uM
Age N/A
Sex N/A
Condition Normal
Comments 1% milk
References
Biofluid Breast_Milk
Value 249 +/- 19 uM
Age N/A
Sex N/A
Condition Normal
Comments 2% milk
References
Biofluid Breast_Milk
Value 238 +/- 16 uM
Age N/A
Sex N/A
Condition Normal
Comments 3.25% milk
References
Biofluid Breast_Milk
Value 45423.868 uM
Age NA
Sex NA
Condition Normal
Comments Cow whole milk (3.25% fat)
References
Biofluid Breast_Milk
Value 54606.78 uM
Age NA
Sex NA
Condition Normal
Comments Cow reduced fat milk (2% fat) with added vitamin A
References
Biofluid Breast_Milk
Value 54817.0756 uM
Age NA
Sex NA
Condition Normal
Comments Cow reduced fat milk (1% fat) with added vitamin A
References
Biofluid Breast_Milk
Value 47366.855 uM
Age NA
Sex NA
Condition Normal
Comments Cow skim milk with added vitamin A
References
Concentrations (Abnormal) Not Available
Pathway Names
  • Arginine and Proline Metabolism
  • Butyrate Metabolism
  • D-Glutamine and D-Glutamate Metabolism
  • Glutamate Metabolism
  • Glutathione Metabolism
  • Histidine Metabolism
  • Nitrogen Metabolism
  • Porphyrin Metabolism
  • Transcription Translation
HMDB Pathways
Name Arginine and Proline Metabolism
Image Show Link Image
Name Butyrate Metabolism
Image Show Link Image
Name D-Glutamine and D-Glutamate Metabolism
Image Show Link Image
Name Glutamate Metabolism
Image Show Link Image
Name Glutathione Metabolism
Image Show Link Image
Name Histidine Metabolism
Image Show Link Image
Name Nitrogen Metabolism
Image Show Link Image
Name Porphyrin Metabolism
Image Show Link Image
Name Transcription Translation
Image Show Link Image
KEGG Pathways
Name Arginine and Proline Metabolism
Image Show Link Image
Name Butyrate Metabolism
Image Show Link Image
Name D-Glutamine and D-Glutamate Metabolism
Image Show Link Image
Name Glutamate Metabolism
Image Show Link Image
Name Glutathione Metabolism
Image Show Link Image
Name Histidine Metabolism
Image Show Link Image
Name Nitrogen Metabolism
Image Show Link Image
Name Porphyrin Metabolism
Image Show Link Image
SimCell Pathways
Name Arginine and Proline Metabolism
Image Show Link Image
Graph
SBML
Name Butyrate Metabolism
Image Show Link Image
Graph
SBML
Name D-Glutamine and D-Glutamate Metabolism
Image Show Link Image
Graph
SBML
Name Glutathione Metabolism
Image Show Link Image
Graph
SBML
Name Histidine Metabolism
Image Show Link Image
Graph
SBML
Name Nitrogen Metabolism
Image Show Link Image
Graph
SBML
Name Porphyrin Metabolism
Image Show Link Image
Graph
SBML
General References
  1. Wikipedia Link Image
Metabolic Enzymes
  1. Glutamine synthetase
  2. Folylpolyglutamate synthase, mitochondrial
  3. Glutathione synthetase
  4. Branched-chain-amino-acid aminotransferase
  5. Branched-chain-amino-acid aminotransferase, mitochondrial
  6. Branched-chain-amino-acid aminotransferase
  7. Branched-chain-amino-acid aminotransferase
  8. Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
  9. Asparagine synthetase [glutamine-hydrolyzing]
  10. Aspartyl aminopeptidase
  11. Aspartate aminotransferase, cytoplasmic
  12. Aspartate aminotransferase, mitochondrial
  13. Putative aspartate aminotransferase, cytoplasmic 2
  14. Glutamyl aminopeptidase
  15. 4-aminobutyrate aminotransferase, mitochondrial
  16. Alpha-aminoadipic semialdehyde synthase, mitochondrial
  17. Probable saccharopine dehydrogenase
  18. Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2
  19. Glutamyl-tRNA(Gln) amidotransferase subunit A homolog
  20. Glutamine-dependent NAD(+) synthetase
  21. Phosphoserine aminotransferase
  22. Glutamate dehydrogenase 1, mitochondrial
  23. 5-oxoprolinase
  24. Alanine aminotransferase 1
  25. Tyrosine aminotransferase
  26. Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
  27. Kynurenine--oxoglutarate transaminase 3
  28. Glutamate decarboxylase 1
  29. PRA1 family protein 3
  30. SLC1A6 protein
  31. Solute carrier family 1 member 2
Enzyme 1 [top]
Enzyme 1 ID 148
Enzyme 1 Name Glutamine synthetase
Enzyme 1 Synonyms
  1. GS
  2. Glutamate--ammonia ligase
Enzyme 1 Gene Name GLUL
Enzyme 1 Protein Sequence >Glutamine synthetase
MATSASSHLNKGIKQVYMALPQGDKVQAMYIWIDGTGEGLRCKTRTLDSEPKCIEELPEW
NFDGSSTFQSEGSNSDMYLVPAAMFRDPFRKDPNKLVFCEVFKYNRKPAETNLRHTCKRI
MDMVSNQRPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHY
RACLYAGIKIGGTNAEVMPAQWEFQIGPCEGIDMGDHLWVARFILHRVCEDFGVIATFDP
KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL
TGFHETSNINDFSAGVANRGASIRIPRTVGQEKKGYFEDRRPSANCDPFAVTEALIRTCL
LNETGDEPFQYKN
Enzyme 1 Number of Residues 373
Enzyme 1 Molecular Weight 42031.2
Enzyme 1 Theoretical pI 6.83
Enzyme 1 GO Classification
Function
Process
Component
Enzyme 1 General Function Amino acid transport and metabolism
Enzyme 1 Specific Function Essential for proliferation of fetal skin fibroblasts
Enzyme 1 Pathways Not Available
Enzyme 1 Reactions Not Available
Enzyme 1 Pfam Domain Function
Enzyme 1 Signals
  • None
Enzyme 1 Transmembrane Regions
  • None
Enzyme 1 Essentiality Not Available
Enzyme 1 GenBank ID Protein 73586743 Link Image
Enzyme 1 UniProtKB/Swiss-Prot ID P15103 Link Image
Enzyme 1 UniProtKB/Swiss-Prot Entry Name GLNA_BOVIN Link Image
Enzyme 1 PDB ID Not Available
Enzyme 1 Cellular Location Not Available
Enzyme 1 Gene Sequence >1122 bp
ATGGCCACCTCGGCGAGCTCCCACTTGAACAAAGGCATCAAGCAGGTGTACATGGCCCTA
CCTCAGGGTGATAAAGTCCAAGCTATGTACATCTGGATCGACGGTACTGGAGAAGGACTG
CGCTGCAAGACCCGAACCTTGGATTCTGAACCCAAGTGTATAGAAGAGTTGCCCGAGTGG
AATTTTGATGGCTCTAGTACTTTTCAGTCTGAAGGCTCCAACAGTGACATGTATCTTGTC
CCCGCTGCCATGTTTCGGGACCCTTTCCGCAAGGACCCCAACAAGCTGGTGTTCTGTGAA
GTCTTCAAGTACAACCGAAAGCCTGCAGAGACCAATTTAAGGCACACCTGTAAACGGATA
ATGGACATGGTGAGCAACCAGCGCCCCTGGTTTGGAATGGAGCAGGAATATACCCTCATG
GGCACTGATGGGCACCCCTTTGGTTGGCCTTCCAATGGCTTTCCTGGGCCCCAAGGTCCC
TACTACTGTGGTGTGGGAGCGGACAAGGCCTACGGCAGGGATATTGTGGAGGCTCACTAC
AGGGCCTGCTTGTACGCCGGCATCAAGATCGGGGGCACGAATGCCGAGGTCATGCCTGCA
CAGTGGGAATTCCAGATAGGACCCTGTGAAGGAATCGACATGGGCGATCATCTCTGGGTG
GCCCGTTTCATCTTGCATCGTGTGTGTGAAGACTTCGGAGTGATCGCCACCTTTGATCCT
AAGCCCATTCCTGGAAACTGGAATGGTGCTGGCTGCCACACCAACTTTAGCACCAAGGCC
ATGCGAGAGGAGAATGGTCTGAAGTACATTGAGGAGGCCATTGAGAAGCTAAGCAAGCGC
CACCAGTACCACATCCGAGCCTACGATCCCAAGGGGGGCCTGGACAACGCCCGGCGCCTA
ACTGGGTTCCACGAAACCTCCAACATCAACGACTTCTCTGCCGGCGTGGCCAACCGTGGT
GCTAGCATCCGCATCCCCCGGACTGTTGGCCAGGAGAAGAAGGGCTACTTCGAAGACCGT
CGCCCATCTGCCAACTGTGACCCCTTCGCCGTGACCGAAGCCCTCATCCGCACATGTCTT
CTGAACGAAACTGGCGACGAGCCCTTCCAGTACAAGAACTAA
Enzyme 1 GenBank Gene ID BC103099 Link Image
Enzyme 1 GeneCard ID GLUL Link Image
Enzyme 1 GenAtlas ID Not Available
Enzyme 1 HGNC ID Not Available
Enzyme 1 Chromosome Location Chromosome:1
Enzyme 1 Locus 1q31
Enzyme 1 SNPs SNPJam Report Link Image
Enzyme 1 General References
  1. [PubMed Link Image]
Enzyme 1 Metabolite References Not Available
Enzyme 2 [top]
Enzyme 2 ID 169
Enzyme 2 Name Folylpolyglutamate synthase, mitochondrial
Enzyme 2 Synonyms
  1. Folylpoly-gamma-glutamate synthetase
  2. FPGS
  3. Tetrahydrofolate synthase
  4. Tetrahydrofolylpolyglutamate synthase
Enzyme 2 Gene Name FPGS
Enzyme 2 Protein Sequence >Folylpolyglutamate synthase, mitochondrial
MSRARCHALFLAAVSPRGATTRVAVRRGLSAWPVLQEPDMEYQDAVRTLNTLQTNANYLE
MVKRKRGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRSYGL
KTGFFSSPHLVQVRERIRINGQPISSELFTKHFWRLYHRLEETKDDSSCVSMPGYFRFLT
LMAFHVFLQEKVDLAVLEVGIGGAYDCTNIIRKPVVCGITSLGIDHTGLLGDTMEKIAWQ
KGGIFKSGVPAFTVLQPDEPLAVLRDRAQQISCPLYLCPPLQALEEGGPPLTLGLEGEHQ
RSNAALALQVARCWLQQKGYQDAGELKASRPSLPGQLPLAPVFQPTPRMQQGLRHTEWPG
RTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALHRCERPDSGSEVRVLLFNSTGDRDSA
ALLKLLQPCQFDYAIFCPNLAEMASTDNADQQNFTVTLDQVLLRCLAHQQHWSRLHEEQV
SPDPWSTPGQEQDGPASLLLAPHPPHTHSASSLVFSCISHALQWITQGRDPLFQPPSPPR
GLLAHPVADSGATVLQEAADIHVLVTGSLHLVGGVLKLLEPSLSQ
Enzyme 2 Number of Residues 585
Enzyme 2 Molecular Weight 64899.8
Enzyme 2 Theoretical pI 7.73
Enzyme 2 GO Classification
Function
Process
Component
Enzyme 2 General Function Coenzyme transport and metabolism
Enzyme 2 Specific Function Conversion of folates to polyglutamate derivatives. This allows tissues to concentrate folate at higher levels than in plasma
Enzyme 2 Pathways
  • Cofactor biosynthesis
  • tetrahydrofolylpolyglutamate biosynthesis
Enzyme 2 Reactions Not Available
Enzyme 2 Pfam Domain Function
Enzyme 2 Signals
  • None
Enzyme 2 Transmembrane Regions
  • None
Enzyme 2 Essentiality Not Available
Enzyme 2 GenBank ID Protein 148877382 Link Image
Enzyme 2 UniProtKB/Swiss-Prot ID A6H751 Link Image
Enzyme 2 UniProtKB/Swiss-Prot Entry Name FOLC_BOVIN Link Image
Enzyme 2 PDB ID Not Available
Enzyme 2 Cellular Location Not Available
Enzyme 2 Gene Sequence >1758 bp
ATGTCTCGGGCACGCTGCCACGCTCTCTTCCTGGCAGCGGTTTCTCCGCGTGGTGCAACA
ACCAGGGTCGCAGTGCGGCGAGGGTTGAGCGCGTGGCCTGTGCTGCAGGAGCCAGACATG
GAGTATCAGGATGCCGTGCGTACACTCAACACCCTGCAGACCAATGCTAACTACTTGGAG
ATGGTGAAGCGTAAGCGGGGTGACCCCCAGACACAGCTGGAAGCCATGAAGCTGTACTTG
GCACGGAGTGGGCTGCAGGTGGAGGACTTGGACCAGCTGAACATTATCCACATCACTGGA
ACCAAGGGGAAGGGCTCCACGTGTGCCTTCACTGAACGTATCCTCCGAAGCTATGGCCTG
AAGACGGGGTTCTTTAGCTCTCCCCACCTGGTGCAGGTGCGTGAGCGGATCCGCATCAAT
GGGCAGCCCATAAGCTCCGAGCTCTTCACCAAGCACTTCTGGCGCCTCTACCACCGGCTG
GAGGAGACCAAGGACGACAGCAGCTGTGTCTCCATGCCCGGCTACTTCCGCTTCCTCACG
CTCATGGCCTTCCACGTCTTCCTCCAAGAGAAGGTAGACCTGGCAGTGTTGGAAGTAGGC
ATTGGCGGGGCTTACGACTGCACCAACATCATCAGGAAGCCTGTGGTGTGTGGGATCACC
TCTCTTGGCATCGACCACACTGGCCTTCTGGGGGACACGATGGAGAAGATCGCATGGCAG
AAAGGGGGCATTTTTAAGAGTGGCGTCCCTGCCTTCACCGTGCTCCAGCCTGACGAGCCG
CTGGCGGTGCTAAGGGACAGGGCTCAGCAGATCTCATGTCCCCTCTACCTGTGCCCACCA
CTACAAGCCCTGGAGGAAGGGGGGCCACCACTGACCCTGGGCCTGGAGGGAGAGCACCAG
CGGTCCAATGCTGCCCTGGCCTTGCAGGTGGCCCGCTGCTGGCTGCAGCAGAAAGGTTAC
CAGGATGCTGGGGAGCTGAAGGCATCCAGGCCCAGCCTCCCGGGGCAGCTGCCCCTGGCA
CCTGTGTTCCAGCCCACGCCCCGCATGCAGCAGGGGCTTCGGCACACGGAATGGCCAGGT
CGGACGCAGTTGCTGCGGCGCGGGCCTCTTACCTGGTACCTGGACGGCGCGCACACCACC
AGCAGCATGCAAGCCTGTGTGCGCTGGTTCCGCCAGGCGCTGCACCGCTGCGAGAGGCCG
GACAGCGGTTCCGAGGTGCGCGTCTTGCTCTTCAACTCCACTGGGGACCGGGATTCCGCG
GCCCTGCTGAAGCTGCTGCAGCCCTGCCAGTTTGACTATGCCATTTTCTGCCCTAACCTG
GCAGAGATGGCATCAACAGACAATGCAGACCAACAGAACTTCACAGTGACACTGGACCAG
GTGCTGCTCCGCTGCCTCGCCCACCAACAGCACTGGAGTCGCCTGCATGAGGAGCAGGTC
AGCCCGGACCCCTGGAGCACCCCCGGCCAGGAGCAGGATGGGCCCGCATCTCTGCTGCTG
GCGCCTCACCCACCCCACACCCACAGTGCCAGCTCCCTCGTCTTCAGCTGCATCTCCCAT
GCCTTGCAGTGGATCACCCAAGGCCGGGACCCTCTCTTTCAGCCGCCCAGTCCCCCACGG
GGCCTCCTCGCCCACCCTGTGGCAGACAGTGGGGCCACGGTACTCCAAGAGGCTGCTGAC
ATTCACGTGCTGGTCACAGGCAGCCTGCACCTGGTGGGCGGTGTCCTGAAGCTGCTGGAG
CCCTCCCTGTCCCAGTAG
Enzyme 2 GenBank Gene ID BC146114 Link Image
Enzyme 2 GeneCard ID FPGS Link Image
Enzyme 2 GenAtlas ID Not Available
Enzyme 2 HGNC ID Not Available
Enzyme 2 Chromosome Location Chromosome:9
Enzyme 2 Locus 9q34.1
Enzyme 2 SNPs SNPJam Report Link Image
Enzyme 2 General References Not Available
Enzyme 2 Metabolite References Not Available
Enzyme 3 [top]
Enzyme 3 ID 197
Enzyme 3 Name Glutathione synthetase
Enzyme 3 Synonyms
  1. Glutathione synthase
  2. GSH synthetase
  3. GSH-S
Enzyme 3 Gene Name GSS
Enzyme 3 Protein Sequence >Glutathione synthetase
MATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQAPSSSHVVSYAPFTLFPSPVPSA
LLEQAYAVQADFNLLVDAVSQNAVFLEQTLSSTIKRDSFTARLFDIHKQVLKEGIAQTVF
LGLNRSDYMFQCNPDGSAALKQIEINTVSASFGGLASRTPAVHRHVLSVLGKTKEAAKIL
SNNPSKGLAMGIAKAWELYGSANAQVLLIAQEKERNIFDQRAIENELLARNIHVIRRKFE
DVSEKGSLDQDRRLFMDGQEIAVVYFRDGYMPGHYSLQNWEARLLLERSCAVKCPDIATQ
LAGTKKVQQELSRVGVLESFLPGQPEAVARLRATFAGLYSLDLGEEGDQAITKAIAAPSC
FVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFRNCLLRPGSPARVI
QCISELGIFGVYVREGKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV
Enzyme 3 Number of Residues 474
Enzyme 3 Molecular Weight 52065.0
Enzyme 3 Theoretical pI 6.44
Enzyme 3 GO Classification
Function
Process
Component
Enzyme 3 General Function Involved in ATP binding
Enzyme 3 Specific Function ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
Enzyme 3 Pathways
  • Sulfur metabolism
  • glutathione biosynthesis
  • glutathione from L-cysteine and L-glutamate:step 2/2
Enzyme 3 Reactions Not Available
Enzyme 3 Pfam Domain Function
Enzyme 3 Signals
  • None
Enzyme 3 Transmembrane Regions
  • None
Enzyme 3 Essentiality Not Available
Enzyme 3 GenBank ID Protein 59857659 Link Image
Enzyme 3 UniProtKB/Swiss-Prot ID Q5EAC2 Link Image
Enzyme 3 UniProtKB/Swiss-Prot Entry Name GSHB_BOVIN Link Image
Enzyme 3 PDB ID Not Available
Enzyme 3 Cellular Location Not Available
Enzyme 3 Gene Sequence >1425 bp
ATGGCCACCGGCTGGGGGAGCCTCTTGCAGGATGAACAGCAGCTGGAGGAGCTAGCAAGG
CAGGCTGTGGACCGGGCTCTGGCTGAGGGTGTGTTGCTGAGGACCTCACAGGCACCCAGC
TCCTCTCATGTGGTGAGCTATGCTCCATTCACACTCTTCCCTTCACCGGTCCCAAGTGCC
CTGCTGGAGCAGGCCTATGCTGTGCAGGCGGACTTCAACCTCCTGGTGGATGCGGTCAGC
CAAAATGCTGTCTTTCTGGAGCAGACTCTCTCCAGCACCATCAAAAGAGACAGCTTTACT
GCTCGTCTCTTTGACATCCACAAGCAAGTCTTAAAAGAAGGCATTGCCCAGACCGTGTTC
CTGGGCTTGAATCGCTCAGACTACATGTTCCAGTGCAATCCGGATGGCTCCGCAGCCCTG
AAACAGATTGAAATCAACACCGTCTCTGCCAGCTTTGGGGGCCTAGCCTCCCGGACCCCA
GCTGTGCATCGACATGTTCTCAGTGTCCTGGGTAAGACCAAAGAAGCTGCCAAGATCCTC
TCCAATAATCCCAGCAAGGGACTGGCCATGGGGATTGCCAAAGCCTGGGAGCTCTACGGC
TCAGCCAATGCTCAGGTGCTACTGATTGCTCAAGAGAAGGAAAGGAACATATTTGACCAG
CGTGCCATAGAGAATGAGCTACTGGCCAGGAATATCCATGTAATCCGACGAAAGTTCGAA
GATGTCTCTGAAAAGGGGTCTCTAGACCAAGACCGAAGACTATTTATGGACGGCCAGGAG
ATTGCTGTGGTTTACTTCCGGGATGGCTACATGCCAGGCCATTACAGCCTACAGAACTGG
GAAGCACGCCTGCTCCTGGAGAGGTCATGTGCTGTCAAGTGCCCGGATATTGCCACCCAG
CTGGCCGGGACCAAGAAGGTGCAGCAGGAGCTGAGCAGAGTGGGCGTGCTGGAGTCCTTT
CTCCCAGGGCAGCCTGAGGCTGTGGCCCGCCTCCGTGCCACCTTTGCTGGCCTCTACTCA
CTAGACCTGGGTGAAGAAGGGGACCAGGCTATCACCAAGGCCATTGCTGCTCCTAGCTGC
TTTGTGCTAAAGCCTCAAAGAGAGGGTGGAGGTAACAACCTATACGGGGAGGAGATGGTA
CAAGCCCTGGAGCGGCTGAAGGACAGTGAGGAGAGAGCCTCCTACATCCTCATGGAGAAG
ATCGAACCCGAGCCTTTTAGGAATTGTCTACTACGACCCGGCAGCCCTGCCCGAGTGATC
CAATGCATTTCAGAGCTGGGCATCTTCGGGGTCTATGTCAGGGAGGGAAAGACACTTGTG
ATGAACAAGCACGTGGGACATCTGCTTCGAACCAAAGCCATCGAGCATGCAGATGGCGGT
GTGGCGGCTGGAGTGGCAGTCCTGGACAACCCGTACCCTGTGTGA
Enzyme 3 GenBank Gene ID BT020647 Link Image
Enzyme 3 GeneCard ID GSS Link Image
Enzyme 3 GenAtlas ID Not Available
Enzyme 3 HGNC ID Not Available
Enzyme 3 Chromosome Location Chromosome:2
Enzyme 3 Locus 20q11.2
Enzyme 3 SNPs SNPJam Report Link Image
Enzyme 3 General References
  1. [PubMed Link Image]
Enzyme 3 Metabolite References Not Available
Enzyme 4 [top]
Enzyme 4 ID 226
Enzyme 4 Name Branched-chain-amino-acid aminotransferase
Enzyme 4 Synonyms Not Available
Enzyme 4 Gene Name BCAT1
Enzyme 4 Protein Sequence >Branched-chain-amino-acid aminotransferase
MKDCNNGCSAEGTGEGGSKETVETFKAEDLIITRATVLKEKPDSSTLVFGTVFTDHMLTV
EWSLELGWEKPRIKPLQNLSLHPGSSAFHYAVELFEGLKAFRGVDNKIRLFRPNLNMDRM
YRSAMRATLPAFDKKELLECIQQLVKLDEEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK
ALLFVILSPVGPYFSTGSFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVEN
ACQQVLWLYGEDNQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRQSILDLAHK
WGEFKVSERYLTMDDLTTAVEENRVREMFGSGTACVVCPVSTILYKDETIHIPTMENGPK
LASRILEKLTDIQYGREESDWTITVA
Enzyme 4 Number of Residues 386
Enzyme 4 Molecular Weight 43185.0
Enzyme 4 Theoretical pI 4.78
Enzyme 4 GO Classification
Function
Process
Component
Enzyme 4 General Function Amino acid transport and metabolism
Enzyme 4 Specific Function 2-oxoglutaric acid + L-isoleucine = (S)-3- methyl-2-oxopentanoic acid + L-glutamic acid
Enzyme 4 Pathways Not Available
Enzyme 4 Reactions Not Available
Enzyme 4 Pfam Domain Function
Enzyme 4 Signals
  • None
Enzyme 4 Transmembrane Regions
  • None
Enzyme 4 Essentiality Not Available
Enzyme 4 GenBank ID Protein 134025168 Link Image
Enzyme 4 UniProtKB/Swiss-Prot ID A4IFQ7 Link Image
Enzyme 4 UniProtKB/Swiss-Prot Entry Name A4IFQ7_BOVIN Link Image
Enzyme 4 PDB ID Not Available
Enzyme 4 Cellular Location Not Available
Enzyme 4 Gene Sequence >1161 bp
ATGAAGGATTGCAATAATGGATGCTCCGCAGAAGGTACCGGAGAAGGCGGATCCAAAGAG
ACGGTGGAGACTTTCAAGGCTGAAGATCTAATAATCACACGAGCCACCGTTTTAAAGGAA
AAACCAGACTCCAGTACTCTGGTTTTTGGAACGGTTTTTACAGATCACATGTTAACAGTG
GAGTGGTCCTTGGAGCTTGGATGGGAGAAACCACGCATCAAACCTCTTCAAAACCTCTCA
CTGCATCCGGGTTCATCGGCTTTCCACTATGCTGTGGAATTATTTGAAGGGTTGAAGGCA
TTTCGAGGAGTAGATAATAAAATTCGTCTGTTTCGGCCAAACCTCAACATGGATAGGATG
TACCGATCTGCTATGAGGGCCACTTTGCCGGCGTTTGACAAGAAAGAGCTTTTAGAGTGT
ATTCAGCAGCTCGTGAAATTGGATGAGGAATGGGTCCCCTACTCAACATCTGCGAGTCTA
TATATCCGTCCTACGTTCATTGGAACTGAGCCTTCTCTGGGGGTCAAGAAGCCGACTAAA
GCCCTGCTCTTTGTAATCTTGAGCCCAGTGGGACCTTATTTTTCCACTGGAAGCTTTAAT
CCTGTGTCCCTGTGGGCCAACCCGAAGTATGTAAGAGCCTGGAAAGGTGGGACCGGAGAC
TGCAAGATGGGAGGGAATTATGGCTCATCTCTTTTTGCCCAATGTGAAGCCGTGGAAAAT
GCATGTCAGCAGGTTCTGTGGCTCTATGGAGAAGATAATCAAATAACTGAAGTTGGAACT
ATGAATCTTTTTCTTTATTGGATAAATGAAGATGGAGAAGAAGAACTGGCAACTCCTCCG
CTAGATGGCATCATTCTTCCAGGAGTGACGAGGCAGAGCATCCTGGACTTGGCACACAAG
TGGGGTGAATTTAAGGTATCAGAGAGATACCTCACCATGGATGACTTGACCACCGCTGTG
GAGGAGAACCGGGTGAGGGAGATGTTTGGTTCAGGCACCGCCTGTGTTGTTTGCCCTGTT
TCGACTATACTGTACAAGGATGAGACTATACACATTCCAACTATGGAGAATGGTCCTAAG
CTTGCAAGCCGCATCTTAGAAAAACTGACTGATATTCAGTACGGAAGAGAAGAGAGCGAC
TGGACAATCACGGTAGCCTGA
Enzyme 4 GenBank Gene ID BC134713 Link Image
Enzyme 4 GeneCard ID BCAT1 Link Image
Enzyme 4 GenAtlas ID Not Available
Enzyme 4 HGNC ID Not Available
Enzyme 4 Chromosome Location Chromosome:1
Enzyme 4 Locus 12p12.1
Enzyme 4 SNPs SNPJam Report Link Image
Enzyme 4 General References Not Available
Enzyme 4 Metabolite References Not Available
Enzyme 5 [top]
Enzyme 5 ID 227
Enzyme 5 Name Branched-chain-amino-acid aminotransferase, mitochondrial
Enzyme 5 Synonyms
  1. BCAT(m)
Enzyme 5 Gene Name BCAT2
Enzyme 5 Protein Sequence >Branched-chain-amino-acid aminotransferase, mitochondrial
MATAALRQIWIPRFLPVPWFLCGSRRYASSSFKAADLQLEMTQEPHKKPDPSQPLLFGKT
FTDHMLMVEWNQEKGWGQPRIQPFQNLTLHPACSALHYSLQLFEGMKAFKGGDQRVRLFR
PWLNMERMLRSALRLCLPSFDKIELLECIRRLVEVDQDWVPGSMGTSLYVRPVLIGNEPS
LGVGHPTRALLFVILSPVGAYFPGDALKPVSLLADPSFIRAWVGGVGNYKLGGNYGPTVL
VQQEAQKKGCEQVLWLYGPDHELTEVGTMNIFVFWTYEDGVLELVTPPLDGIILPGIVRQ
SLLDLARTWGEFRVVERKITMKEFLRALKDGRVREVFGSGTACQVCPVHQILYQGKHFHI
PTMENGPQLILRFHKELKAIQYGSKAHEWMLPV
Enzyme 5 Number of Residues 393
Enzyme 5 Molecular Weight 44647.8
Enzyme 5 Theoretical pI 8.82
Enzyme 5 GO Classification
Function
Process
Component
Enzyme 5 General Function Amino acid transport and metabolism
Enzyme 5 Specific Function Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids
Enzyme 5 Pathways Not Available
Enzyme 5 Reactions Not Available
Enzyme 5 Pfam Domain Function
Enzyme 5 Signals
  • None
Enzyme 5 Transmembrane Regions
  • None
Enzyme 5 Essentiality Not Available
Enzyme 5 GenBank ID Protein 59857823 Link Image
Enzyme 5 UniProtKB/Swiss-Prot ID Q5EA40 Link Image
Enzyme 5 UniProtKB/Swiss-Prot Entry Name BCAT2_BOVIN Link Image
Enzyme 5 PDB ID Not Available
Enzyme 5 Cellular Location Not Available
Enzyme 5 Gene Sequence >1182 bp
ATGGCTACAGCGGCATTGAGGCAGATTTGGATCCCCAGATTTCTCCCTGTTCCTTGGTTT
CTGTGTGGTTCCAGAAGATATGCCTCATCCAGCTTCAAGGCTGCTGACCTGCAGCTGGAA
ATGACACAGGAGCCTCATAAGAAGCCTGACCCCAGCCAGCCTCTGCTGTTCGGGAAGACA
TTCACCGACCACATGCTGATGGTGGAATGGAATCAGGAGAAGGGCTGGGGCCAGCCCCGA
ATCCAGCCCTTCCAGAACCTCACGCTGCACCCGGCCTGCTCCGCTCTGCACTACTCCCTG
CAGCTCTTTGAAGGCATGAAGGCATTCAAAGGTGGGGACCAGCGCGTGCGCCTCTTCCGA
CCTTGGCTCAACATGGAACGGATGCTGCGCTCGGCCCTCCGCCTCTGCCTACCGAGTTTC
GACAAAATTGAGTTGCTGGAGTGCATCCGCCGGCTGGTGGAAGTGGACCAGGACTGGGTC
CCTGGCAGCATGGGCACTAGCCTCTACGTTCGGCCCGTGTTGATCGGGAACGAGCCCTCG
CTAGGTGTCGGCCACCCTACTCGAGCCCTCCTGTTCGTCATTCTCAGCCCTGTGGGCGCC
TACTTCCCTGGAGATGCCTTGAAACCTGTCTCCCTCCTGGCAGATCCATCATTCATCCGG
GCCTGGGTGGGTGGGGTCGGCAACTACAAGCTGGGAGGGAATTACGGGCCCACCGTGTTA
GTGCAGCAGGAGGCACAAAAGAAGGGCTGCGAGCAGGTCCTCTGGCTGTATGGGCCTGAT
CACGAGCTCACGGAGGTGGGCACCATGAACATCTTCGTCTTCTGGACCTATGAGGACGGG
GTGCTGGAACTGGTGACCCCCCCACTGGACGGCATCATCCTACCTGGAATAGTCCGACAG
AGTCTGCTGGACCTGGCCCGGACCTGGGGTGAATTCCGAGTGGTAGAGCGTAAGATTACC
ATGAAGGAGTTCCTGCGGGCGCTGAAGGATGGCCGGGTCCGAGAAGTCTTCGGTTCAGGC
ACTGCTTGCCAGGTCTGCCCCGTGCACCAAATCCTGTACCAAGGCAAGCATTTCCACATT
CCCACCATGGAAAACGGGCCCCAGCTCATCCTCCGCTTCCACAAGGAACTGAAGGCGATC
CAGTACGGATCAAAAGCCCATGAATGGATGCTCCCGGTGTAA
Enzyme 5 GenBank Gene ID BT020729 Link Image
Enzyme 5 GeneCard ID BCAT2 Link Image
Enzyme 5 GenAtlas ID Not Available
Enzyme 5 HGNC ID Not Available
Enzyme 5 Chromosome Location Chromosome:1
Enzyme 5 Locus 19q13
Enzyme 5 SNPs SNPJam Report Link Image
Enzyme 5 General References
  1. [PubMed Link Image]
Enzyme 5 Metabolite References Not Available
Enzyme 6 [top]
Enzyme 6 ID 228
Enzyme 6 Name Branched-chain-amino-acid aminotransferase
Enzyme 6 Synonyms Not Available
Enzyme 6 Gene Name BCAT2
Enzyme 6 Protein Sequence >Branched-chain-amino-acid aminotransferase
ALRQIWIPRFLPVPWFLCGSRRYASSSFKAADLQLEMTQEPHKKPDPSQPLLFGKTFTDH
MLMVEWNQEKGWGQPRIQPFQNLTLHPACSALHYSLQLFEGMKAFKGGDQRVRLFRPWLN
MERMLRSALRLCLPSFDKIELLECIRRLVEVDQDWVPGSMGTSLYVRPVLIGNEPSLGVG
HPTRALLFVILSPVGAYFPGDALKPVSLLADPSFIRAWVGGVGNYKLGGNYGPTVLVQQE
AQKKGCEQVLWLYGPDHELTEVGTMNIFVFWTYEDGVLELVTPPLDGIILPGIVRQSLLD
LARTWGEFRVVERKITMKEFLRALKDGRVREVFGSGTACQVCPVHQILYQGKHFHIPTME
NGPQLILRFHKELKAIQYGSKAHEWMLPV
Enzyme 6 Number of Residues 389
Enzyme 6 Molecular Weight 44273.4
Enzyme 6 Theoretical pI 8.82
Enzyme 6 GO Classification
Function
Process
Component
Enzyme 6 General Function Amino acid transport and metabolism
Enzyme 6 Specific Function 2-oxoglutaric acid + L-isoleucine = (S)-3- methyl-2-oxopentanoic acid + L-glutamic acid
Enzyme 6 Pathways Not Available
Enzyme 6 Reactions Not Available
Enzyme 6 Pfam Domain Function
Enzyme 6 Signals
  • None
Enzyme 6 Transmembrane Regions
  • None
Enzyme 6 Essentiality Not Available
Enzyme 6 GenBank ID Protein 110331911 Link Image
Enzyme 6 UniProtKB/Swiss-Prot ID Q0V8J6 Link Image
Enzyme 6 UniProtKB/Swiss-Prot Entry Name Q0V8J6_BOVIN Link Image
Enzyme 6 PDB ID Not Available
Enzyme 6 Cellular Location Not Available
Enzyme 6 Gene Sequence Not Available
Enzyme 6 GenBank Gene ID BT026222 Link Image
Enzyme 6 GeneCard ID BCAT2 Link Image
Enzyme 6 GenAtlas ID Not Available
Enzyme 6 HGNC ID Not Available
Enzyme 6 Chromosome Location Chromosome:1
Enzyme 6 Locus 19q13
Enzyme 6 SNPs SNPJam Report Link Image
Enzyme 6 General References
  1. [PubMed Link Image]
Enzyme 6 Metabolite References Not Available
Enzyme 7 [top]
Enzyme 7 ID 229
Enzyme 7 Name Branched-chain-amino-acid aminotransferase
Enzyme 7 Synonyms Not Available
Enzyme 7 Gene Name BCAT2
Enzyme 7 Protein Sequence >Branched-chain-amino-acid aminotransferase
MATAALRQIWIPRFLPVPWFLCGSRRYASSSFKAADLQLEMTQEPHKKPDPSQPLLFGKT
FTDHMLMVEWNQEKGWGQPRIQPFQNLTLHPACSALHYSLQLFEGMKAFKGGDQRVRLFR
PWLNMERMLRSALRLCLPSFDKIELLECIRRLVEVDQDWVPGSMGTSLYVRPVLIGNEPS
LGVGHPTRALLFVILSPVGAYFPGDALKPVSLLADPSFIRAWVGGVGNYKLGGNYGPTVL
VQQEAQKKGCEQVLWLYGPDHELTEVGTMNIFVFWTYEDGVLELVTPPLDGIILPGIVRE
VFGSGTACQVCPVHQILYQGKHFHIPTMENGPQLILRFHKELKAIQYGSKAHEWMLPV
Enzyme 7 Number of Residues 358
Enzyme 7 Molecular Weight 40446.9
Enzyme 7 Theoretical pI 8.08
Enzyme 7 GO Classification
Function
Process
Component
Enzyme 7 General Function Amino acid transport and metabolism
Enzyme 7 Specific Function 2-oxoglutaric acid + L-isoleucine = (S)-3- methyl-2-oxopentanoic acid + L-glutamic acid
Enzyme 7 Pathways Not Available
Enzyme 7 Reactions Not Available
Enzyme 7 Pfam Domain Function
Enzyme 7 Signals
  • None
Enzyme 7 Transmembrane Regions
  • None
Enzyme 7 Essentiality Not Available
Enzyme 7 GenBank ID Protein 59858011 Link Image
Enzyme 7 UniProtKB/Swiss-Prot ID Q5E9U7 Link Image
Enzyme 7 UniProtKB/Swiss-Prot Entry Name Q5E9U7_BOVIN Link Image
Enzyme 7 PDB ID Not Available
Enzyme 7 Cellular Location Not Available
Enzyme 7 Gene Sequence >1077 bp
ATGGCTACAGCGGCATTGAGGCAGATTTGGATCCCCAGATTTCTCCCTGTTCCTTGGTTT
CTGTGTGGTTCCAGAAGATATGCCTCATCCAGCTTCAAGGCTGCTGACCTGCAGCTGGAA
ATGACACAGGAGCCTCATAAGAAGCCTGACCCCAGCCAGCCTCTGCTGTTCGGGAAGACA
TTCACCGACCACATGCTGATGGTGGAATGGAATCAGGAGAAGGGCTGGGGCCAGCCCCGA
ATCCAGCCCTTCCAGAACCTCACGCTGCACCCGGCCTGCTCCGCTCTGCACTACTCCCTG
CAGCTCTTTGAAGGCATGAAGGCATTCAAAGGTGGGGACCAGCGCGTGCGCCTCTTCCGA
CCTTGGCTCAACATGGAACGGATGCTGCGCTCGGCCCTCCGCCTCTGCCTACCGAGTTTC
GACAAAATTGAGTTGCTGGAGTGCATCCGCCGGCTGGTGGAAGTGGACCAGGACTGGGTC
CCTGGCAGCATGGGCACTAGCCTCTACGTTCGGCCCGTGTTGATCGGGAACGAGCCCTCG
CTAGGTGTCGGCCACCCTACTCGAGCCCTCCTGTTCGTCATTCTCAGCCCTGTGGGCGCC
TACTTCCCTGGAGATGCCTTGAAACCTGTCTCCCTCCTGGCAGATCCATCATTCATCCGG
GCCTGGGTGGGTGGGGTCGGCAACTACAAGCTGGGAGGGAATTACGGGCCCACCGTGTTA
GTGCAGCAGGAGGCACAAAAGAAGGGCTGCGAGCAGGTCCTCTGGCTGTATGGGCCTGAT
CACGAGCTCACGGAGGTGGGCACCATGAACATCTTCGTCTTCTGGACCTATGAGGACGGG
GTGCTGGAACTGGTGACCCCCCCACTGGACGGCATCATCCTACCTGGAATAGTCCGAGAA
GTCTTCGGTTCAGGCACTGCTTGCCAGGTCTGCCCCGTGCACCAAATCCTGTACCAAGGC
AAGCATTTCCACATTCCCACCATGGAAAACGGGCCCCAGCTCATCCTCCGCTTCCACAAG
GAACTGAAGGCGATCCAGTACGGATCAAAAGCCCATGAATGGATGCTCCCGGTGTAA
Enzyme 7 GenBank Gene ID BT020823 Link Image
Enzyme 7 GeneCard ID BCAT2 Link Image
Enzyme 7 GenAtlas ID Not Available
Enzyme 7 HGNC ID Not Available
Enzyme 7 Chromosome Location Chromosome:1
Enzyme 7 Locus 19q13
Enzyme 7 SNPs SNPJam Report Link Image
Enzyme 7 General References
  1. [PubMed Link Image]
Enzyme 7 Metabolite References Not Available
Enzyme 8 [top]
Enzyme 8 ID 239
Enzyme 8 Name Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Enzyme 8 Synonyms
  1. KAT/AadAT
  2. Kynurenine aminotransferase II
  3. Kynurenine--oxoglutarate aminotransferase II
  4. Kynurenine--oxoglutarate transaminase II
  5. 2-aminoadipate transaminase
  6. 2-aminoadipate aminotransferase
  7. Alpha-aminoadipate aminotransferase
  8. AadAT
Enzyme 8 Gene Name AADAT
Enzyme 8 Protein Sequence >Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
MNYARFITATSAARKPSTIRVMTEILSKAPKSVISLATGAPNPNTFPFKTAVITIENGKP
IQFNEQMMKRALQYSQSAGIPELLSWLKQLQVKLHNPPTIHYAPTQGQMDLCVTCGSQEG
LCKVFEMIVNPGDNILVNEPIYSGTIHALQPLGCNMINVSSDEHGIIPDSLREILSKWKP
EDSKNPKKNSPKFLYTVPNGNNPSGNSLTAERKREIYELARKYDFLIIEDDPYYFMQFNK
PWAPTFLSMDEDGRVIRADSFSKVLSSGLRIGFITGPKPLIERIVLHIQVSTMHPSTFAQ
LLVSQLLYQWGEEGFLGHVDRVIDFYRKQRDALMAAADKWLSGLAEWHVPTAGMFLWVKI
KGIHDVRKLIEEKAFKKEIFMLPGCGFYTDSSAPCPYFRASFSSASPEQMDLAFQRLAQL
IKESL
Enzyme 8 Number of Residues 425
Enzyme 8 Molecular Weight 47900.9
Enzyme 8 Theoretical pI 8.72
Enzyme 8 GO Classification
Function
Process
Component
Enzyme 8 General Function Transcription
Enzyme 8 Specific Function Shows activity also towards tryptophan, aspartate and hydroxykinurenine
Enzyme 8 Pathways
  • Amino-acid degradation
  • L-lysine degradation via saccharopine pathway
  • glutaryl-CoA from L-lysine:step 4/6
Enzyme 8 Reactions Not Available
Enzyme 8 Pfam Domain Function
Enzyme 8 Signals
  • None
Enzyme 8 Transmembrane Regions
  • None
Enzyme 8 Essentiality Not Available
Enzyme 8 GenBank ID Protein 59858053 Link Image
Enzyme 8 UniProtKB/Swiss-Prot ID Q5E9N4 Link Image
Enzyme 8 UniProtKB/Swiss-Prot Entry Name AADAT_BOVIN Link Image
Enzyme 8 PDB ID Not Available
Enzyme 8 Cellular Location Not Available
Enzyme 8 Gene Sequence >1278 bp
ATGAATTACGCTCGGTTCATTACCGCCACGAGCGCGGCCAGAAAGCCTTCTACCATCCGA
GTCATGACTGAAATATTGAGCAAGGCACCGAAATCTGTCATCTCCTTGGCAACTGGGGCA
CCAAACCCCAACACGTTCCCTTTCAAGACTGCGGTCATCACCATAGAAAACGGAAAACCC
ATCCAATTTAATGAACAGATGATGAAGAGAGCACTGCAGTATTCTCAGAGTGCTGGAATC
CCAGAGCTGTTATCCTGGCTAAAACAGTTACAAGTAAAATTGCATAATCCGCCCACCATC
CATTATGCACCCACCCAAGGACAGATGGACTTATGTGTCACATGTGGCAGCCAAGAAGGT
CTCTGTAAGGTATTTGAAATGATCGTTAATCCTGGAGATAATATCCTTGTAAATGAACCT
ATTTATTCAGGAACAATTCATGCTCTGCAACCCCTGGGCTGCAACATGATTAATGTTTCC
AGTGATGAGCACGGGATTATTCCAGACTCCCTCAGAGAAATACTTTCCAAATGGAAACCA
GAAGATTCAAAGAACCCCAAGAAAAACAGCCCCAAATTTCTTTACACTGTCCCAAATGGC
AACAACCCCTCTGGGAACTCATTAACAGCTGAGCGCAAAAGGGAAATCTATGAGCTCGCA
AGAAAATATGACTTCCTCATCATAGAAGATGATCCTTACTATTTTATGCAGTTCAACAAG
CCCTGGGCACCGACATTTCTCTCCATGGACGAGGATGGGCGCGTCATCCGAGCTGACTCT
TTTTCCAAAGTCCTGTCCTCAGGGTTGAGAATAGGGTTTATAACTGGTCCAAAGCCCTTG
ATTGAGAGAATTGTTTTACACATACAAGTTTCAACAATGCACCCCAGCACTTTTGCTCAG
CTCCTGGTATCACAGCTTCTATACCAATGGGGAGAAGAGGGCTTCCTGGGTCACGTAGAC
AGGGTTATTGATTTCTACAGGAAGCAGAGGGATGCATTAATGGCAGCAGCAGACAAGTGG
TTAAGTGGTTTGGCAGAATGGCATGTTCCTACTGCAGGAATGTTTCTATGGGTTAAAATT
AAGGGCATTCATGATGTAAGAAAACTGATCGAAGAAAAAGCCTTTAAGAAAGAGATATTC
ATGCTTCCGGGATGTGGTTTCTACACTGACAGTTCAGCTCCTTGCCCGTACTTCAGAGCA
TCCTTCTCTTCAGCTTCTCCAGAACAGATGGACTTGGCCTTTCAGAGACTGGCCCAACTT
ATAAAAGAATCTTTATGA
Enzyme 8 GenBank Gene ID BT020844 Link Image
Enzyme 8 GeneCard ID AADAT Link Image
Enzyme 8 GenAtlas ID Not Available
Enzyme 8 HGNC ID Not Available
Enzyme 8 Chromosome Location Chromosome:4
Enzyme 8 Locus 4q33
Enzyme 8 SNPs SNPJam Report Link Image
Enzyme 8 General References
  1. [PubMed Link Image]
Enzyme 8 Metabolite References Not Available
Enzyme 9 [top]
Enzyme 9 ID 563
Enzyme 9 Name Asparagine synthetase [glutamine-hydrolyzing]
Enzyme 9 Synonyms
  1. Glutamine-dependent asparagine synthetase
Enzyme 9 Gene Name ASNS
Enzyme 9 Protein Sequence >Asparagine synthetase [glutamine-hydrolyzing]
MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDQLFGMQ
PIRVKKYPYLWLCYNGEIYNHKKLQHHFEFEYQTKVDGEIILHLYDKGGIEQTVCMLDGV
FAFILLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVNLKHSMTPFLKVEPF
LPGHYEVLDLKPNGKVASVEMVKHHHCRDEPLHALYDGVEKLFPGFEIETVKSNLRILFD
NAVKKRLMTDRRIGCLLSGGLDSSLVAATLLKQLKEAQVQYPLQTFAIGMEDSPDLLAAR
KVANHIGSEHHEVLFNSEEGIQVLDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVV
IFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLRELYLFDVLRADRTTAAHGLELRVPF
LDHRFSSYYLSLPPDMRVPKNGIEKHLLRETFEDSNLIPKEILWRPKEAFSDGITSVKNS
WFRILQDYIEHQVDDAAMASAAQKFPINTPKTKEGYYYRQIFENHYPGRADWLPHYWMPR
WTNATDPSARTLTHYKAAAKA
Enzyme 9 Number of Residues 561
Enzyme 9 Molecular Weight 64219.1
Enzyme 9 Theoretical pI 6.77
Enzyme 9 GO Classification
Function
Process
Component
Enzyme 9 General Function Amino acid transport and metabolism
Enzyme 9 Specific Function ATP + L-aspartate + L-glutamine + H(2)O = AMP + diphosphate + L-asparagine + L-glutamate
Enzyme 9 Pathways
  • Amino-acid biosynthesis
  • L-asparagine biosynthesis
  • L- asparagine from L-aspartate (L-Gln route):step 1/1
Enzyme 9 Reactions Not Available
Enzyme 9 Pfam Domain Function
Enzyme 9 Signals
  • None
Enzyme 9 Transmembrane Regions
  • None
Enzyme 9 Essentiality Not Available
Enzyme 9 GenBank ID Protein 94534952 Link Image
Enzyme 9 UniProtKB/Swiss-Prot ID Q1LZA3 Link Image
Enzyme 9 UniProtKB/Swiss-Prot Entry Name ASNS_BOVIN Link Image
Enzyme 9 PDB ID Not Available
Enzyme 9 Cellular Location Not Available
Enzyme 9 Gene Sequence >1686 bp
ATGTGTGGCATTTGGGCGCTCTTTGGCAGCGATGACTGCCTTTCTGTTCAGTGTCTGAGT
GCTATGAAGATTGCACACAGGGGTCCGGATGCATTCCGTTTTGAAAATGTTAATGGGTAC
ACCAATTGCTGCTTTGGATTTCACCGGTTGGCGGTAGTTGACCAGCTGTTTGGAATGCAG
CCAATTCGAGTGAAGAAATATCCTTACTTGTGGCTCTGTTACAACGGTGAAATCTACAAC
CACAAGAAGCTGCAACACCATTTTGAATTTGAATACCAGACCAAAGTGGATGGTGAAATA
ATCCTTCATCTTTATGACAAAGGAGGAATTGAACAAACAGTTTGTATGTTGGATGGAGTA
TTTGCATTTATTTTACTGGATACTGCCAATAAGAAAGTGTTCTTGGGCAGAGATACCTAT
GGAGTGAGACCTTTGTTTAAAGCCATGACAGAAGATGGATTTTTGGCCGTGTGTTCAGAA
GCTAAAGGACTGGTTAACTTGAAGCACTCCATGACTCCTTTTTTAAAAGTGGAGCCTTTT
CTGCCAGGACATTATGAAGTTTTGGACCTAAAGCCAAATGGCAAAGTGGCGTCGGTGGAA
ATGGTGAAGCACCATCACTGTAGAGACGAGCCTCTGCATGCCCTGTATGACGGCGTGGAG
AAACTCTTCCCAGGTTTTGAGATAGAAACTGTGAAGAGCAACCTCCGGATTCTTTTTGAC
AATGCCGTTAAGAAACGTTTGATGACGGACAGAAGGATTGGCTGCCTTTTATCAGGTGGC
TTGGATTCCAGTTTGGTTGCTGCCACTCTGTTGAAGCAGCTAAAAGAGGCCCAAGTTCAG
TACCCTCTCCAGACATTTGCGATTGGCATGGAAGACAGTCCCGATTTACTAGCTGCTAGA
AAGGTGGCAAATCATATTGGGAGCGAACACCATGAAGTCCTCTTTAACTCTGAGGAAGGC
ATTCAGGTCCTGGATGAAGTCATATTTTCCTTGGAAACTTATGATATTACAACAGTCCGT
GCTTCAGTAGGTATGTACTTAATTTCTAAGTACATTCGGAAGAACACAGATAGCGTGGTG
ATCTTCTCTGGAGAAGGTTCAGATGAACTTACGCAGGGTTATATATATTTTCACAAGGCT
CCTTCCCCGGAGAAAGCTGAGGAGGAGAGTGAGCGGCTTCTAAGGGAACTCTACTTGTTT
GATGTTCTCCGAGCAGATCGAACTACTGCAGCCCATGGCCTTGAATTGAGAGTCCCTTTC
TTGGATCATCGCTTTTCTTCCTACTACTTGTCTCTGCCACCAGATATGAGAGTTCCCAAG
AATGGGATAGAAAAGCATCTCCTGAGAGAGACATTTGAGGACTCCAATCTGATACCTAAA
GAGATTCTCTGGCGACCAAAAGAAGCCTTCAGTGATGGAATAACCTCAGTTAAAAATTCC
TGGTTTAGGATTTTACAGGACTATATTGAACATCAGGTTGATGATGCAGCGATGGCAAGC
GCAGCCCAGAAATTTCCCATCAATACCCCCAAAACAAAAGAAGGCTATTACTACCGTCAG
ATCTTTGAAAACCACTACCCAGGCCGTGCCGACTGGCTGCCCCATTACTGGATGCCCAGG
TGGACCAACGCCACGGACCCTTCTGCCCGCACTCTGACCCATTACAAGGCCGCTGCCAAA
GCTTAG
Enzyme 9 GenBank Gene ID BC116123 Link Image
Enzyme 9 GeneCard ID ASNS Link Image
Enzyme 9 GenAtlas ID Not Available
Enzyme 9 HGNC ID Not Available
Enzyme 9 Chromosome Location Chromosome:7
Enzyme 9 Locus 7q21.3
Enzyme 9 SNPs SNPJam Report Link Image
Enzyme 9 General References Not Available
Enzyme 9 Metabolite References Not Available
Enzyme 10 [top]
Enzyme 10 ID 566
Enzyme 10 Name Aspartyl aminopeptidase
Enzyme 10 Synonyms Not Available
Enzyme 10 Gene Name DNPEP
Enzyme 10 Protein Sequence >Aspartyl aminopeptidase
MSGRARKEAVQAAARELLKFVNRSPSPFHAVAECRSRLLQAGFHELKETESWDIKPESKY
FLTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRSRRSQVGFQQVGVETYGGG
IWSTWFDRDLTLAGRVIVKCPTSGRLEQRLVHVDRPILRIPHLAIHLQRNVNENFGPNME
MHLVPILATSIQEELEKGTPEPGPLNATDERHHSVLTSLLCAHLGLSPEDILEMELCLAD
TQPAVLGGAYEEFIFAPRLDNLHSCFCALQALIDSCSAPASLAADPHVRMIALYDNEEVG
SESAQGAQSLLTELVLRRISASPQHLTAFEEAIPKSYMISADMAHAVHPNYLDKHEENHR
PLFHKGPVIKVNSKQRYASNAVSEALIREVASSVGVPLQDLMVRNDSPCGTTIGPILASR
LGLRVLDLGSPQLAMHSIRETACTTGVLQTITLFKGFFELFPSLSRSLLVD
Enzyme 10 Number of Residues 471
Enzyme 10 Molecular Weight 51827.8
Enzyme 10 Theoretical pI 6.92
Enzyme 10 GO Classification
Function
Process
Component
Enzyme 10 General Function Amino acid transport and metabolism
Enzyme 10 Specific Function Likely to play an important role in intracellular protein and peptide metabolism
Enzyme 10 Pathways Not Available
Enzyme 10 Reactions Not Available
Enzyme 10 Pfam Domain Function
Enzyme 10 Signals
  • None
Enzyme 10 Transmembrane Regions
  • None
Enzyme 10 Essentiality Not Available
Enzyme 10 GenBank ID Protein 88682882 Link Image
Enzyme 10 UniProtKB/Swiss-Prot ID Q2HJH1 Link Image
Enzyme 10 UniProtKB/Swiss-Prot Entry Name DNPEP_BOVIN Link Image
Enzyme 10 PDB ID Not Available
Enzyme 10 Cellular Location Not Available
Enzyme 10 Gene Sequence >1416 bp
ATGAGCGGCAGGGCCCGCAAAGAGGCGGTTCAGGCCGCGGCCCGGGAACTGCTCAAGTTC
GTCAACCGGAGCCCCTCTCCTTTCCACGCGGTGGCCGAGTGCCGCAGTCGCCTCCTCCAG
GCCGGCTTCCATGAACTCAAGGAGACCGAGAGCTGGGATATCAAGCCGGAGAGCAAGTAC
TTCCTGACCAGGAACTCCTCCACCATCATCGCATTTGCTGTGGGGGGCCAGTACGTTCCC
GGCAATGGTTTCAGCCTCATTGGGGCCCACACGGACAGTCCCTGCCTCCGGGTGAAACGG
CGCTCTCGCCGCAGCCAGGTGGGCTTCCAGCAGGTTGGTGTGGAGACCTATGGTGGTGGG
ATCTGGAGCACCTGGTTTGACCGTGACCTGACCTTGGCTGGACGTGTCATTGTCAAGTGC
CCTACCTCAGGCCGGCTGGAGCAGCGGCTGGTGCACGTGGACAGGCCCATTCTTCGCATC
CCGCACCTGGCCATCCACCTGCAGAGAAATGTCAATGAGAATTTTGGGCCCAACATGGAG
ATGCACTTGGTCCCCATTCTTGCCACATCCATCCAGGAGGAGCTGGAGAAGGGGACTCCT
GAGCCAGGCCCCCTCAATGCTACAGATGAGCGGCACCACTCGGTCCTCACGTCCCTTCTC
TGCGCCCATCTGGGGCTGAGCCCCGAGGACATCTTGGAGATGGAACTGTGTCTCGCCGAC
ACTCAGCCAGCGGTCCTGGGTGGTGCCTACGAGGAGTTCATTTTTGCCCCTCGGCTGGAC
AACCTGCACAGCTGCTTCTGTGCCCTGCAGGCCTTGATCGATTCCTGCTCAGCCCCTGCC
TCTCTGGCCGCGGATCCCCACGTGCGCATGATCGCCCTCTATGACAATGAAGAGGTGGGG
TCAGAGAGTGCACAGGGCGCACAGTCACTGCTGACGGAGCTGGTGCTGCGGCGGATCTCG
GCTTCGCCCCAGCACCTGACGGCCTTCGAGGAAGCCATCCCCAAGTCCTACATGATCAGC
GCAGACATGGCCCATGCCGTGCACCCCAACTACCTGGACAAGCATGAGGAGAACCACAGG
CCCTTATTCCACAAGGGCCCTGTGATCAAGGTGAACAGCAAGCAACGCTATGCCTCAAAT
GCGGTTTCAGAGGCCCTGATCCGAGAGGTGGCCAGCAGTGTCGGGGTGCCCCTGCAGGAT
CTCATGGTCCGGAATGACTCGCCCTGCGGCACCACCATCGGACCTATCTTGGCCTCTCGG
CTAGGTCTGCGGGTGCTGGATTTAGGCAGCCCCCAGCTGGCCATGCATTCCATCCGGGAG
ACAGCCTGCACCACAGGAGTACTCCAGACCATCACTCTCTTTAAGGGCTTCTTTGAGCTG
TTCCCTTCTCTGAGCCGTAGCCTCCTGGTAGACTGA
Enzyme 10 GenBank Gene ID BC105402 Link Image
Enzyme 10 GeneCard ID DNPEP Link Image
Enzyme 10 GenAtlas ID Not Available
Enzyme 10 HGNC ID Not Available
Enzyme 10 Chromosome Location Chromosome:2
Enzyme 10 Locus 2q35
Enzyme 10 SNPs SNPJam Report Link Image
Enzyme 10 General References Not Available
Enzyme 10 Metabolite References Not Available
Enzyme 11 [top]
Enzyme 11 ID 567
Enzyme 11 Name Aspartate aminotransferase, cytoplasmic
Enzyme 11 Synonyms
  1. Transaminase A
  2. Glutamate oxaloacetate transaminase 1
Enzyme 11 Gene Name GOT1
Enzyme 11 Protein Sequence >Aspartate aminotransferase, cytoplasmic
MAPPSIFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDSQPWVLPVVRKVEQR
IANDSSINHEYLPILGLAEFRTCASRLALGDDSPALQEKRVGGVQCLGGTGALRIGAEFL
ARWYNGTNNKDTPVYVSSPTWENHNGVFIAAGFKDIRSYHYWDAAKRGLDLQGFLNDLEK
APEFSIFVLHACAHNPTGTDPTPEQWKQIASVMKRRFLFPFFDSAYQGFASGSLEKDAWA
IRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVAKEPDSILRVLSQMEKIVRITWSNPP
AQGARIVARTLSDPELFNEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITEQIGM
FSFTGLNPKQVEYLINEKHIYLLPSGRINMCGLTTKNLEYVATSIHEAVTKIQ
Enzyme 11 Number of Residues 413
Enzyme 11 Molecular Weight 46398.5
Enzyme 11 Theoretical pI 7.56
Enzyme 11 GO Classification
Function
Process
Component
Enzyme 11 General Function Amino acid transport and metabolism
Enzyme 11 Specific Function L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
Enzyme 11 Pathways Not Available
Enzyme 11 Reactions Not Available
Enzyme 11 Pfam Domain Function
Enzyme 11 Signals
  • None
Enzyme 11 Transmembrane Regions
  • None
Enzyme 11 Essentiality Not Available
Enzyme 11 GenBank ID Protein 184 Link Image
Enzyme 11 UniProtKB/Swiss-Prot ID P33097 Link Image
Enzyme 11 UniProtKB/Swiss-Prot Entry Name AATC_BOVIN Link Image
Enzyme 11 PDB ID 1AJS Link Image
Enzyme 11 PDB File Show
Enzyme 11 3D Structure
Enzyme 11 Cellular Location Not Available
Enzyme 11 Gene Sequence >1242 bp
ATGGCGCCTCCATCAATCTTTGCCGAGGTTCCTCAGGCCCAGCCGGTCCTTGTCTTTAAG
CTAACTGCTGACTTCCGGGAGGATCCGGACCCCCGCAAGGTCAACCTGGGAGTGGGAGCT
TATCGCACCGATGATAGCCAGCCCTGGGTTTTACCAGTCGTGAGGAAGGTGGAGCAGAGG
ATTGCTAACGACAGCAGCATAAACCATGAGTATCTGCCCATCCTGGGCCTGGCAGAGTTC
CGAACTTGTGCTTCCCGCCTGGCCCTTGGGGATGACAGCCCAGCTCTGCAAGAGAAGCGG
GTGGGAGGGGTGCAGTGCTTGGGGGGAACAGGTGCACTTCGAATCGGAGCTGAGTTCTTG
GCGCGCTGGTACAATGGAACAAACAACAAGGACACACCCGTCTATGTGTCCTCGCCAACC
TGGGAGAATCATAATGGTGTCTTTATTGCTGCTGGATTTAAAGACATTCGGTCCTATCAC
TATTGGGATGCAGCGAAGAGAGGACTAGACCTCCAGGGTTTCCTGAATGATTTGGAGAAA
GCTCCCGAGTTCTCCATCTTTGTCCTCCATGCCTGTGCGCACAACCCGACTGGGACTGAC
CCGACTCCGGAGCAGTGGAAGCAGATCGCCTCCGTCATGAAGCGCCGGTTTCTGTTCCCC
TTCTTTGACTCGGCCTATCAGGCGTTCGCATCTGGCAGCCTGGAGAAAGACGCCTGGGCC
ATTCGCTATTTTGTGTCTGAAGGGTTCGAGCTCTTCTGTGCCCAGTCCTTCTCCAAAAAC
TTCGGGCTCTACAATGAGCGTGTGGGGAATCTGACTGTGGTTGCCAAAGAACCAGATAGC
ATCCTGCGGGTCCTTTCCCAGATGGAGAAGATCGTGCGAATTACATGGTCCAATCCCCCA
GCTCAGGGAGCACGGATCGTGGCACGTACCCTGTCTGATCCTGAGCTCTTTAATGAATGG
ACAGGTAACGTGAAGACAATGGCAGACCGCATTCTGACCATGAGATCTGAGCTCAGGGCA
CGATTAGAAGCCCTCAAGACCCCAGGAACCTGGAACCACATCACAGAGCAGATCGGAATG
TTCAGCTTCACCGGGTTGAACCCCAAGCAGGTTGAGTATCTGATCAATGAAAAGCACATC
TATCTGCTGCCAAGTGGTCGGATCAACATGTGTGGCTTAACCACCAAAAATCTAGAGTAC
GTGGCCACCTCCATCCATGAAGCAGTCACCAAAATCCAGTGA
Enzyme 11 GenBank Gene ID X66020 Link Image
Enzyme 11 GeneCard ID GOT1 Link Image
Enzyme 11 GenAtlas ID Not Available
Enzyme 11 HGNC ID Not Available
Enzyme 11 Chromosome Location Chromosome:1
Enzyme 11 Locus 10q24.1-q25.1
Enzyme 11 SNPs SNPJam Report Link Image
Enzyme 11 General References
  1. [PubMed Link Image]
Enzyme 11 Metabolite References Not Available
Enzyme 12 [top]
Enzyme 12 ID 569
Enzyme 12 Name Aspartate aminotransferase, mitochondrial
Enzyme 12 Synonyms
  1. mAspAT
  2. Transaminase A
  3. Glutamate oxaloacetate transaminase 2
  4. Fatty acid-binding protein
  5. FABP-1
  6. FABPpm
Enzyme 12 Gene Name GOT2
Enzyme 12 Protein Sequence >Aspartate aminotransferase, mitochondrial
MALLHSGRFLSGVAAAFHPGLAAAASARASSWWAHVEMGPPDPILGVTEAFKRDTNSKKM
NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIAGLAEFCKASAELALGENNEV
LKSGRYVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQSYR
YYDPKTCGFDFTGAIEDISKIPAQSVILLHACAHNPTGVDPRPEQWKEMATVVKKNNLFA
FFDMAYQGFASGDGNKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEE
AKRVESQLKILIRPMYSNPPINGARIASTILTSPDLRKQWLHEVKGMADRIISMRTQLVS
NLKKEGSSHNWQHIIDQIGMFCYTGLKPEQVERLTKEFSIYMTKDGRISVAGVTSGNVAY
LAHAIHQVTK
Enzyme 12 Number of Residues 430
Enzyme 12 Molecular Weight 47513.2
Enzyme 12 Theoretical pI 9.45
Enzyme 12 GO Classification
Function
Process
Component
Enzyme 12 General Function Amino acid transport and metabolism
Enzyme 12 Specific Function Facilitates cellular uptake of long-chain free fatty acids
Enzyme 12 Pathways Not Available
Enzyme 12 Reactions Not Available
Enzyme 12 Pfam Domain Function
Enzyme 12 Signals
  • None
Enzyme 12 Transmembrane Regions
  • None
Enzyme 12 Essentiality Not Available
Enzyme 12 GenBank ID Protein 415324 Link Image
Enzyme 12 UniProtKB/Swiss-Prot ID P12344 Link Image
Enzyme 12 UniProtKB/Swiss-Prot Entry Name AATM_BOVIN Link Image
Enzyme 12 PDB ID Not Available
Enzyme 12 Cellular Location Not Available
Enzyme 12 Gene Sequence >1293 bp
ATGGCCCTGCTGCACTCTGGCCGCTTCCTGTCCGGAGTCGCCGCGGCTTTCCACCCAGGC
CTCGCTGCCGCGGCTTCTGCCAGAGCCAGCTCCTGGTGGGCTCATGTGGAGATGGGGCCC
CCAGATCCCATCCTGGGAGTAACAGAAGCCTTTAAGAGAGACACCAACAGCAAAAAGATG
AACCTGGGAGTTGGTGCCTACCGGGATGATAATGGAAAGCCTTACGTGCTTCCAAGTGTC
CGGAAGGCGGAGGCCCAGATTGCTGCAAAAAATTTGGATAAAGAATACCTGCCCATTGCG
GGGCTGGCTGAATTTTGTAAGGCATCTGCAGAACTAGCCCTGGGTGAGAACAATGAAGTG
TTGAAAAGTGGCCGGTATGTCACCGTGCAGACCATTTCTGGAACCGGGGCCTTAAGGATC
GGAGCCAGTTTTCTGCAAAGATTTTTTAAGTTCAGCCGGGATGTCTTCCTGCCCAAACCA
ACCTGGGGGAATCATACACCCATCTTCAGGGATGCTGGCATGCAGCTCCAGAGTTATCGG
TACTATGACCCCAAGACGTGCGGCTTTGACTTCACAGGCGCTATTGAGGACATTTCAAAA
ATACCAGCGCAGAGTGTCATTCTCCTGCACGCCTGTGCCCACAACCCCACGGGAGTGGAC
CCTCGTCCTGAGCAGTGGAAGGAGATGGCGACAGTGGTGAAGAAAAACAATCTCTTTGCA
TTCTTTGACATGGCCTACCAAGGCTTTGCCAGTGGCGATGGTAACAAGGATGCCTGGGCT
GTGCGCCACTTCATCGAACAGGGCATTAATGTTTGTCTCTGCCAGTCCTATGCCAAGAAC
ATGGGCTTATACGGTGAGCGTGTGGGAGCCTTCACTGTGGTCTGCAAAGATGCCGAGGAA
GCCAAAAGAGTTGAGTCCCAGTTGAAGATCCTGATCCGTCCCATGTATTCCAACCCCCCT
ATCAATGGGGCCCGGATTGCCTCCACTATTCTCACCAGCCCGGATTTGCGGAAACAATGG
TTGCACGAAGTGAAGGGCATGGCCGACCGCATCATCAGCATGCGGACACAGCTGGTGTCC
AACCTCAAGAAGGAGGGCTCCTCCCACAACTGGCAGCACATCATTGACCAGATCGGCATG
TTTTGTTACACAGGCCTAAAGCCTGAACAGGTGGAGCGGCTGACCAAGGAGTTCTCCATC
TACATGACAAAGGATGGCCGCATCTCTGTGGCAGGGGTCACCTCAGGCAACGTGGCATAC
CTTGCTCACGCCATTCACCAGGTCACCAAGTAA
Enzyme 12 GenBank Gene ID Z25466 Link Image
Enzyme 12 GeneCard ID GOT2 Link Image
Enzyme 12 GenAtlas ID Not Available
Enzyme 12 HGNC ID Not Available
Enzyme 12 Chromosome Location Chromosome:1
Enzyme 12 Locus 16q21
Enzyme 12 SNPs SNPJam Report Link Image
Enzyme 12 General References
  1. [PubMed Link Image]
Enzyme 12 Metabolite References Not Available
Enzyme 13 [top]
Enzyme 13 ID 571
Enzyme 13 Name Putative aspartate aminotransferase, cytoplasmic 2
Enzyme 13 Synonyms
  1. Transaminase A-like protein 1
  2. Glutamate oxaloacetate transaminase 1-like protein 1
Enzyme 13 Gene Name GOT1L1
Enzyme 13 Protein Sequence >Putative aspartate aminotransferase, cytoplasmic 2
MPTLSVFTDVPMAQKLEGSLLKTYKQDDNPNKMFLAYKVCMTSKGRPWVSSVVRKTRMQI
AQDPSLNYEYTPVMGMKSFVQASLNLLFGKNSQVIVENRAGGVQTVGDSGAFQLGAQFLK
SWCQSSQIVYIVSSQKEPHGLIFQDMGFTVYEHTFWDSAHLCLDPNMLLDVVKHAPHGCV
FVIGSMGNCQLTPSQWTQLMTLMKSKEIFPFFDIPYQGLSTGDLEEDARFLHYFVSQGFE
FFCSQSLSKNFGIYDEGVGTLVVVTLDNQLLLRVLSQLMNFARALWLNPPTTGARIITSV
LCNPAMQGEWRQSLEGVVENVMMTKEKVKEKLRLLGTPGSWDHITEQKGSHSYLGLNSQQ
VEYLISEKHIYIPKNGRINFTCINSYNIDYITSSINEAVCFTKDSER
Enzyme 13 Number of Residues 407
Enzyme 13 Molecular Weight 45917.5
Enzyme 13 Theoretical pI 6.97
Enzyme 13 GO Classification
Function
Process
Component
Enzyme 13 General Function Amino acid transport and metabolism
Enzyme 13 Specific Function L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
Enzyme 13 Pathways Not Available
Enzyme 13 Reactions Not Available
Enzyme 13 Pfam Domain Function
Enzyme 13 Signals
  • None
Enzyme 13 Transmembrane Regions
  • None
Enzyme 13 Essentiality Not Available
Enzyme 13 GenBank ID Protein 83406131 Link Image
Enzyme 13 UniProtKB/Swiss-Prot ID Q2T9S8 Link Image
Enzyme 13 UniProtKB/Swiss-Prot Entry Name AATC2_BOVIN Link Image
Enzyme 13 PDB ID Not Available
Enzyme 13 Cellular Location Not Available
Enzyme 13 Gene Sequence >1224 bp
ATGCCCACTCTGTCTGTGTTCACAGATGTGCCCATGGCCCAGAAGCTAGAGGGCAGCTTG
CTCAAGACCTACAAGCAAGATGACAACCCTAACAAGATGTTCCTGGCCTATAAAGTCTGC
ATGACCAGCAAAGGCAGACCCTGGGTGTCCTCCGTGGTGCGCAAGACTCGAATGCAGATT
GCCCAAGATCCCTCCCTGAACTATGAGTACACGCCGGTGATGGGCATGAAATCATTCGTC
CAGGCTTCCCTGAACCTCCTCTTTGGAAAGAACAGCCAAGTCATTGTGGAGAACAGGGCA
GGGGGTGTGCAAACCGTCGGGGACAGCGGCGCTTTCCAACTCGGGGCTCAGTTCCTCAAA
TCTTGGTGTCAGAGTTCTCAGATAGTTTACATCGTTTCTTCTCAAAAAGAACCTCATGGA
CTCATCTTCCAGGACATGGGCTTTACAGTTTATGAACACACCTTCTGGGACTCTGCGCAT
CTGTGCTTGGACCCTAACATGCTCCTCGATGTGGTGAAGCATGCCCCGCATGGCTGCGTC
TTTGTGATCGGGAGTATGGGCAACTGTCAGCTGACCCCTAGTCAGTGGACACAGTTGATG
ACCCTGATGAAGAGCAAGGAGATATTTCCATTTTTTGACATTCCCTATCAAGGTTTATCC
ACTGGTGACCTGGAGGAGGATGCTAGATTCTTACACTACTTTGTGTCTCAAGGCTTTGAG
TTTTTCTGCAGCCAGTCTCTATCCAAGAATTTTGGCATTTATGATGAAGGAGTGGGCACT
CTCGTGGTGGTGACCCTCGACAACCAGCTCCTGCTGCGCGTCCTCTCCCAGCTGATGAAC
TTTGCGCGGGCCCTGTGGCTAAACCCTCCCACCACGGGCGCTCGCATCATCACCTCTGTC
CTCTGTAACCCTGCTATGCAGGGAGAATGGAGACAGAGTCTGGAAGGGGTTGTAGAGAAC
GTCATGATGACCAAGGAAAAGGTGAAGGAGAAGCTCCGGCTTCTGGGAACCCCTGGCTCC
TGGGATCACATCACTGAGCAGAAAGGGTCCCACAGCTATCTTGGACTCAACTCCCAACAG
GTGGAATACCTGATCAGTGAAAAGCATATCTATATCCCTAAGAATGGTCGGATCAACTTC
ACCTGTATCAATTCCTACAACATAGATTACATCACTTCGAGCATCAATGAGGCTGTCTGC
TTCACAAAGGACTCAGAGAGATAG
Enzyme 13 GenBank Gene ID BC111285 Link Image
Enzyme 13 GeneCard ID GOT1L1 Link Image
Enzyme 13 GenAtlas ID Not Available
Enzyme 13 HGNC ID Not Available
Enzyme 13 Chromosome Location Chromosome:8
Enzyme 13 Locus 8p12
Enzyme 13 SNPs SNPJam Report Link Image
Enzyme 13 General References Not Available
Enzyme 13 Metabolite References Not Available
Enzyme 14 [top]
Enzyme 14 ID 572
Enzyme 14 Name Glutamyl aminopeptidase
Enzyme 14 Synonyms
  1. EAP
  2. Aminopeptidase A
  3. APA
  4. CD249 antigen
Enzyme 14 Gene Name ENPEP
Enzyme 14 Protein Sequence >Glutamyl aminopeptidase
MILEERSSWEGSKRYCIKTKHVAIICAVVVAVGLIVGLSVGLTRSCDSTEGMTQGTTQGT
TQAPSHLPPVTSPPEDQGVCPASEDESGGWKDFRLPDFIKPVHYDLEVKPLMEQDTYTGS
VDISINVSSSTRYLWLHLRETRITRLPVLRRPSGEQVQVRQCFEYKKQEYVVVEAEEELE
PNTGEGPYHLILEFAGWLNGSLVGFYRTTYVEKGQTKSIAATDHEPTDARKSFPCFDEPN
KKATYTISIVHSKEYKALSNMPVEKEESVDDIWSRTTFQKSVPMSTYLVCFAVHQFDSVT
RISNRGIPLTIYVQPEQKHTAEYAANITKSVFDYFEDYFGMSYSLPKLDKIAIPDFGTGA
MENWGLITYRETNLLYDPDESASSNKQRVAAVIAHELVHQWFGNIVTMEWWDDLWLNEGF
ASFFEYLGVAYAEKDWQMRDQMILDDVLPVQEDDSLMSSHPIVVTVATPDEITSVFDGIS
YSKGASILRMLENWITREKFQIGCQNYLKKHKFENAKTSDFWAALEEASNLPVKEVMDTW
TNQMGYPVLNVDNMKNITQKRFLLDPRANASEPHSAFGYTWNIPIKWTEDDEQRITLYNR
SETGGITLESTLSGNAFLKINPDHIGFYRVNYEVSTWEWIATNLSVNHTDFSSADRASFI
DDAFALARAQLLNYKEALNLTKYLKEEKEYLPWHRVISAVTYIISMFEDDKELYPVIEKY
FRDQVKPIADSLGWNDVGDHLTKLLRASVLGLACKMGDSDALNNASQLFQEWLTGTVSLP
VNLRLLVYRYGMQNSGNETSWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLL
KDSNLIKTQDVFTVIQYISYNSYGKTMAWNWIQLNWEYLVNRYTLNNRNLGRIVTIAEPF
NTELQLWQIKSFFERYPEAGAGQKPREQVLETVKNNIEWLKQNRDTIRNWFLDLNG
Enzyme 14 Number of Residues 956
Enzyme 14 Molecular Weight 109800.1
Enzyme 14 Theoretical pI 4.92
Enzyme 14 GO Classification
Function
Process
Component
Enzyme 14 General Function Amino acid transport and metabolism
Enzyme 14 Specific Function Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells
Enzyme 14 Pathways Not Available
Enzyme 14 Reactions Not Available
Enzyme 14 Pfam Domain Function
Enzyme 14 Signals
  • None
Enzyme 14 Transmembrane Regions
  • 22-42
Enzyme 14 Essentiality Not Available
Enzyme 14 GenBank ID Protein 81674650 Link Image
Enzyme 14 UniProtKB/Swiss-Prot ID Q32LQ0 Link Image
Enzyme 14 UniProtKB/Swiss-Prot Entry Name AMPE_BOVIN Link Image
Enzyme 14 PDB ID Not Available
Enzyme 14 Cellular Location Not Available
Enzyme 14 Gene Sequence >2871 bp
ATGATCTTGGAGGAGAGATCATCTTGGGAAGGCTCTAAGAGATACTGCATTAAGACGAAA
CATGTGGCCATTATCTGCGCAGTGGTGGTGGCTGTCGGATTAATAGTAGGACTTTCTGTG
GGTCTGACCAGATCATGTGACTCTACAGAGGGCATGACCCAGGGCACGACCCAGGGCACG
ACCCAGGCTCCTTCCCACCTGCCTCCCGTTACCAGCCCTCCAGAGGACCAGGGGGTCTGC
CCTGCCAGTGAGGATGAAAGCGGAGGCTGGAAAGACTTCAGGCTGCCGGACTTCATCAAA
CCAGTGCACTACGACCTGGAGGTGAAGCCCCTGATGGAGCAGGACACGTACACGGGCAGC
GTGGACATCTCCATCAACGTGAGCTCATCCACCCGGTACCTGTGGCTACATCTCCGGGAG
ACGAGGATCACCAGGCTCCCGGTGCTGAGGAGGCCGTCTGGGGAGCAGGTTCAAGTCAGG
CAGTGCTTCGAATACAAGAAGCAGGAGTATGTGGTGGTGGAAGCAGAAGAAGAGCTTGAG
CCCAACACTGGCGAGGGTCCCTACCACCTGATCCTGGAGTTCGCCGGCTGGCTGAACGGC
TCGCTCGTGGGATTTTACAGAACGACATACGTGGAGAAAGGACAAACCAAGAGCATAGCA
GCCACTGATCATGAACCAACAGATGCCAGGAAATCCTTCCCTTGTTTTGATGAGCCCAAC
AAAAAGGCAACGTATACAATATCCATTGTCCACTCCAAAGAATATAAGGCGCTTTCGAAT
ATGCCAGTGGAGAAAGAAGAGTCAGTGGATGATATATGGAGTCGGACAACTTTCCAGAAG
TCTGTTCCCATGAGTACTTACCTGGTGTGCTTTGCAGTGCATCAGTTTGACTCTGTAACG
AGAATATCAAACAGGGGGATACCTCTCACTATATATGTCCAGCCAGAGCAAAAGCACACA
GCTGAATATGCTGCAAACATAACTAAAAGTGTGTTTGACTATTTTGAAGACTACTTTGGT
ATGAGTTATTCTCTTCCTAAATTAGATAAAATTGCTATTCCAGATTTCGGCACTGGGGCT
ATGGAGAACTGGGGACTCATCACTTACAGAGAAACAAACCTGCTTTATGACCCTGATGAA
TCTGCCTCATCAAACAAACAGAGGGTGGCTGCTGTGATAGCCCATGAGCTTGTGCATCAG
TGGTTTGGAAATATTGTGACCATGGAATGGTGGGACGACTTGTGGCTAAATGAAGGATTT
GCTTCCTTCTTTGAGTACCTGGGAGTAGCCTATGCAGAAAAAGACTGGCAAATGCGTGAT
CAGATGATACTTGATGATGTATTACCTGTGCAAGAGGATGATTCTTTGATGTCTTCACAC
CCAATAGTAGTCACTGTAGCAACTCCTGATGAAATAACATCTGTTTTTGATGGAATTTCC
TATAGTAAGGGAGCTTCCATTCTGAGAATGCTTGAAAACTGGATAACACGAGAGAAATTT
CAAATAGGATGTCAGAATTACTTGAAAAAACACAAATTTGAGAATGCCAAAACTTCAGAT
TTCTGGGCAGCACTTGAAGAGGCAAGTAATCTCCCAGTGAAAGAAGTAATGGACACCTGG
ACCAATCAGATGGGTTACCCTGTACTTAACGTGGACAATATGAAGAACATCACACAGAAA
CGCTTTCTATTGGACCCGAGAGCTAATGCTTCTGAGCCACATTCAGCTTTTGGTTACACA
TGGAATATTCCAATTAAATGGACTGAAGATGATGAACAAAGGATTACATTATACAATAGG
TCAGAAACAGGAGGAATCACTTTGGAATCTACTCTTAGTGGGAATGCTTTTCTCAAAATA
AACCCTGATCATATTGGCTTTTATCGTGTAAATTATGAAGTGTCAACTTGGGAATGGATA
GCTACGAATCTTTCCGTCAACCACACGGACTTTTCTTCTGCTGATCGTGCAAGTTTTATT
GATGATGCTTTTGCCTTGGCACGAGCTCAGCTTCTAAATTATAAGGAGGCTCTGAACTTG
ACCAAGTATCTCAAGGAAGAAAAGGAATATTTACCATGGCACAGAGTCATTTCAGCTGTA
ACCTATATTATTAGCATGTTTGAAGATGATAAAGAGCTATACCCTGTGATTGAGAAATAC
TTCCGAGATCAAGTGAAGCCCATTGCAGATTCTCTGGGATGGAATGATGTTGGAGACCAC
CTCACAAAATTACTCCGTGCGTCTGTATTAGGACTGGCGTGCAAGATGGGAGACAGCGAT
GCCTTGAACAACGCTTCCCAGTTATTTCAGGAGTGGCTAACTGGGACTGTAAGTCTTCCT
GTAAATCTCAGGCTTCTGGTATATCGGTATGGTATGCAGAACTCTGGCAATGAGACTTCA
TGGAATTACACTCTCGAGCAATACCAGAAAACTTCATTAGCTCAAGAAAAAGAAAAGCTA
CTGTATGGATTAGCATCAGTGAAGAATGTTACTCTTTTGTCAAGGTATTTGGATTTACTC
AAGGACTCAAACCTTATTAAAACGCAGGATGTGTTTACAGTCATTCAGTACATCTCATAC
AACAGCTATGGGAAGACTATGGCCTGGAATTGGATACAACTCAACTGGGAATATCTAGTC
AACAGGTATACACTCAATAACAGAAACCTTGGCCGGATTGTCACTATAGCAGAGCCATTC
AACACTGAACTACAACTCTGGCAGATCAAGAGCTTTTTCGAAAGATATCCTGAAGCTGGA
GCGGGACAAAAACCTAGGGAGCAAGTACTGGAAACAGTGAAAAACAATATCGAGTGGCTA
AAACAAAACAGGGACACCATAAGAAACTGGTTTCTTGATTTGAATGGTTAA
Enzyme 14 GenBank Gene ID BC109476 Link Image
Enzyme 14 GeneCard ID ENPEP Link Image
Enzyme 14 GenAtlas ID Not Available
Enzyme 14 HGNC ID Not Available
Enzyme 14 Chromosome Location Chromosome:4
Enzyme 14 Locus 4q25
Enzyme 14 SNPs SNPJam Report Link Image
Enzyme 14 General References Not Available
Enzyme 14 Metabolite References Not Available
Enzyme 15 [top]
Enzyme 15 ID 596
Enzyme 15 Name 4-aminobutyrate aminotransferase, mitochondrial
Enzyme 15 Synonyms
  1. Gamma-amino-N-butyrate transaminase
  2. GABA transaminase
  3. GABA-T
  4. GABA aminotransferase
  5. GABA-AT
  6. L-AIBAT
  7. (S)-3-amino-2-methylpropionate transaminase
Enzyme 15 Gene Name ABAT
Enzyme 15 Protein Sequence >4-aminobutyrate aminotransferase, mitochondrial
MASMLVAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGRLMKTEVPGLRCQELMK
QLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPGLLKLIQQPQ
NASMFVNRPALGILLPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENGLKTIFMWYR
SKERGQRGFPQEELETCMINQAPWCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPS
FDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGG
DNHASDDFFRKLRDIPRKQCCAFLVDVVQTGGGCTGKFWAHEHWARDDPEDVMTSSKKMM
TGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLL
DLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVF
RDHHAHLFLNIFSDILADFK
Enzyme 15 Number of Residues 500
Enzyme 15 Molecular Weight 56730.9
Enzyme 15 Theoretical pI 8.21
Enzyme 15 GO Classification
Function
Process
Component
Enzyme 15 General Function Amino acid transport and metabolism
Enzyme 15 Specific Function Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine
Enzyme 15 Pathways Not Available
Enzyme 15 Reactions Not Available
Enzyme 15 Pfam Domain Function
Enzyme 15 Signals
  • None
Enzyme 15 Transmembrane Regions
  • None
Enzyme 15 Essentiality Not Available
Enzyme 15 GenBank ID Protein 12584862 Link Image
Enzyme 15 UniProtKB/Swiss-Prot ID Q9BGI0 Link Image
Enzyme 15 UniProtKB/Swiss-Prot Entry Name GABT_BOVIN Link Image
Enzyme 15 PDB ID Not Available
Enzyme 15 Cellular Location Not Available
Enzyme 15 Gene Sequence >1503 bp
ATGGCGTCCATGTTGGTCGCCCAGCGCCTGGCCTGCAGCTTCCAGCACAGCTACCGCCTG
CTGGTGCCTGGATCCAGACACATTAGTCAAGCTGCAGCCAAAGTCGACGTTGAATTTGAT
TATGATGGGCGTCTGATGAAGACGGAAGTCCCAGGGCTTAGATGTCAGGAGTTAATGAAA
CAGCTGAATATAATTCAGAATGCAGAGGCTGTGCATTTTTTCTGCAATTACGAAGAGAGC
CGAGGCAATTACCTGGTTGATGTGGACGGCAACCGAATGCTGGATCTTTATTCCCAGATC
TCCTCTGTCCCCATAGGTTACAGCCACCCCGGCCTGCTGAAACTCATCCAACAGCCTCAA
AATGCGAGCATGTTTGTCAACAGACCCGCCCTCGGAATCCTGCTTCCGGAGAACTTTGTG
GAGAAGCTCCGGCAGTCCTTGCTCTCGGTGGCTCCCAAAGGGATGTCCCAGCTCATCACC
ATGGCCTGCGGCTCCTGCTCCAATGAAAACGGCTTAAAGACCATCTTCATGTGGTACCGG
AGCAAGGAAAGAGGGCAGAGGGGCTTCCCCCAAGAGGAGCTGGAGACGTGCATGATTAAC
CAGGCCCCCTGGTGCCCCGACTACAGCATCCTCTCCTTCATGGGCGCGTTCCATGGGAGG
ACCATGGGTTGCTTAGCGACCACGCACTCTAAAGCCATTCACAAGATCGACATCCCTTCC
TTTGACTGGCCCATCGCACCGTTCCCACGGCTGAAATACCCTCTGGAAGAGTTTGTGAAA
GAGAACCAACAGGAGGAGGCCCGCTGTCTGGAAGAGGTGGAGGATCTGATTGTGAAATAT
CGGAAAAAGAAGAAGACGGTGGCCGGGATCATCGTGGAGCCCATCCAGTCCGAGGGTGGA
GACAACCACGCATCCGATGACTTCTTTCGGAAGCTGAGAGACATCCCCAGGAAGCAATGC
TGCGCCTTCTTGGTGGACGTGGTCCAGACCGGAGGAGGCTGCACGGGCAAGTTCTGGGCC
CACGAGCACTGGGCCCGGGATGACCCAGAAGACGTGATGACCTCCAGCAAGAAGATGATG
ACTGGGGGCTTCTTCCACAAGGAGGAGTTCAGGCCTAATGCTCCCTACCGGATCTTCAAC
ACCTGGCTGGGGGACCCGTCCAAGAACCTGTTGCTGGCTGAGGTCATCAACATCATCAAG
CGGGAGGACCTGCTAAATAATGCAGCCCATGCCGGGAAGGCCCTGCTCACAGGACTGCTG
GACCTCCAGGCCCGGTACCCCCAGTTCATCAGCAGGGTGAGAGGACGAGGCACCTTTTGC
TCCTTCGATACTCCCGATGATTCCATACGGAATAAGCTCATTTTAATTGCCAGAAACAAA
GGTGTGGTGTTGGGTGGCTGTGGTGACAAATCCATTCGTTTCCGTCCCACGCTGGTGTTC
AGGGATCACCACGCACACCTGTTCCTCAATATTTTCAGTGACATCTTAGCAGACTTCAAG
TAA
Enzyme 15 GenBank Gene ID AF305692 Link Image
Enzyme 15 GeneCard ID ABAT Link Image
Enzyme 15 GenAtlas ID Not Available
Enzyme 15 HGNC ID Not Available
Enzyme 15 Chromosome Location Chromosome:1
Enzyme 15 Locus 16p13.2
Enzyme 15 SNPs SNPJam Report Link Image
Enzyme 15 General References
  1. [PubMed Link Image]
Enzyme 15 Metabolite References Not Available
Enzyme 16 [top]
Enzyme 16 ID 631
Enzyme 16 Name Alpha-aminoadipic semialdehyde synthase, mitochondrial
Enzyme 16 Synonyms
  1. LKR/SDH
  2. Lysine ketoglutarate reductase
  3. LKR
  4. LOR
  5. Saccharopine dehydrogenase
  6. SDH
Enzyme 16 Gene Name AASS
Enzyme 16 Protein Sequence >Alpha-aminoadipic semialdehyde synthase, mitochondrial
MLRVSRTKLGRLSPSLSRGLHHKAVMALRREDVNAWERRAPLAPRHVKGITNLGYKVLIQ
PSNRRAIHDKEYVKAGGILQEDISEACLILGVKRPPEEKLMPKKTYAFFSHTIKAQEANM
GLLDEILKQEIRLIDYEKMVDHRGIRVVAFGQWAGVAGIINILHGMGLRLLALGHHTPFM
HIGMAHNYRNSGQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQEIFNELPC
EYVEPHELKEVSQNGDLRKVYGTVLSRHHHLVRKTDGVYDPVEYDKYPERYISRFNTDIA
PYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKSPVAGVEGCPALPHKLVAICDISADTG
GSIEFMTECTTIERPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIESTEYFGDMLY
PYVEEMILSDATQPLESQNFSPVVRDAVIASNGMLSNKYKYIQKLRENREHAQSLSMGTK
KKVLVLGSGYVSEPVLEYLLRDDSIEITVGSDMKNQIEQLGKKYNINPVSLHVGKQEEKL
SSLVATQDLVISLLPYVLHPLVAKACIASKVNMITASYITPALKELEKSVEDAGITVIGE
LGLDPGLDHMLAMETIDKAKEVGATIESYVSYCGGLPAPECSDNPLRYKFSWSPVGVLMN
IMQPATYLLNGKVVNAVGGVSFLDSVTPMDYFPGLNLEGYPNRDSTKYAEIYGIPSAHTL
LRGTLRYKGYAKALSGFVKLGLINRDAFPALQPDANPLTWKELLCDLVGISSSSKCDVLK
EAVFKKLGGDTTQLEALEWLGLLGDEQVPQAESLVDALSKHLAVKLSYGPGEKDMIVMRD
SFGIRHPSGHLENKTIDLVVYGDVNGFSAMAKTVGLPTAMAAKMLLDGEIQAKGLMGPFS
KEIYGPILERIKAEGIMYTTQSTIKL
Enzyme 16 Number of Residues 926
Enzyme 16 Molecular Weight 102083.0
Enzyme 16 Theoretical pI 6.70
Enzyme 16 GO Classification
Function
Process
Component
Enzyme 16 General Function Amino acid transport and metabolism
Enzyme 16 Specific Function Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-oxoglutarate reductase and saccharopine dehydrogenase activity, respectively
Enzyme 16 Pathways
  • Amino-acid degradation
  • L-lysine degradation via saccharopine pathway
  • glutaryl-CoA from L-lysine:step 2/6
Enzyme 16 Reactions Not Available
Enzyme 16 Pfam Domain Function
Enzyme 16 Signals
  • None
Enzyme 16 Transmembrane Regions
  • None
Enzyme 16 Essentiality Not Available
Enzyme 16 GenBank ID Protein 157743061 Link Image
Enzyme 16 UniProtKB/Swiss-Prot ID A8E657 Link Image
Enzyme 16 UniProtKB/Swiss-Prot Entry Name AASS_BOVIN Link Image
Enzyme 16 PDB ID Not Available
Enzyme 16 Cellular Location Not Available
Enzyme 16 Gene Sequence >2781 bp
ATGCTGCGAGTGTCCAGAACCAAACTGGGCAGGCTGAGCCCCAGCCTCTCCAGAGGGCTT
CACCACAAGGCGGTGATGGCCTTGAGGCGGGAGGATGTGAATGCCTGGGAAAGGCGGGCT
CCTCTGGCTCCCCGGCACGTCAAAGGGATCACCAACCTGGGATACAAGGTCTTAATACAG
CCTTCCAATCGGCGAGCCATTCACGATAAGGAATATGTCAAAGCTGGTGGCATTCTCCAA
GAGGATATTTCTGAAGCTTGTCTAATTTTGGGAGTTAAAAGACCGCCAGAGGAAAAATTA
ATGCCCAAGAAGACTTATGCATTCTTCTCCCACACAATAAAGGCTCAGGAGGCCAATATG
GGTTTGCTGGATGAGATCCTAAAACAGGAAATCCGACTTATTGATTATGAGAAAATGGTG
GATCATAGAGGAATACGGGTGGTGGCATTCGGACAGTGGGCAGGTGTGGCAGGAATAATC
AACATTCTTCATGGGATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCTTTTATG
CACATTGGCATGGCTCATAACTACAGGAACAGTGGTCAGGCTGTGCAAGCTGTCCGCGAT
GCTGGCTATGAAATATCTTTGGGTTTGATGCCGAAGTCAATAGGGCCCTTAACATTTGTG
TTCACAGGGACTGGTAATGTATCTAAGGGAGCCCAAGAAATCTTCAATGAATTACCTTGT
GAGTATGTGGAGCCACATGAATTAAAAGAAGTTTCCCAAAATGGAGACCTGAGAAAAGTG
TACGGGACAGTGTTAAGTCGCCATCATCATCTTGTCAGGAAAACAGATGGTGTATATGAC
CCTGTAGAGTATGACAAATACCCCGAGCGCTACATTAGCCGTTTTAATACTGATATTGCA
CCCTATACAACTTGTTTAATTAACGGGATCTACTGGGAACAGAACACCCCTCGTCTACTC
ACCCGCCAAGATGCTCAGAGTCTCCTGGCTCCAGGCAAGTCCCCAGTTGCTGGTGTTGAA
GGCTGCCCTGCATTGCCACACAAACTTGTGGCAATATGTGACATTTCAGCGGACACAGGA
GGATCCATTGAGTTTATGACTGAGTGTACGACCATAGAGCGTCCCTTTTGCATGTATGAT
GCAGATCAGCATATTATTCATGACAGTGTGGAAGGCTCTGGGATTCTGATGTGTTCCATT
GACAATTTGCCAGCACAGCTTCCAATTGAATCTACAGAATACTTTGGAGACATGCTTTAC
CCTTATGTTGAAGAAATGATACTATCAGATGCGACACAGCCTCTTGAAAGTCAGAATTTT
TCTCCTGTGGTGCGAGATGCAGTGATTGCATCTAATGGCATGCTGTCTAACAAGTATAAA
TATATCCAGAAACTCCGAGAGAACAGGGAACATGCTCAGTCACTTTCAATGGGCACCAAG
AAAAAGGTCTTGGTTCTTGGATCTGGTTACGTTTCTGAGCCTGTATTGGAATACCTGTTG
AGAGATGACAGTATTGAAATAACAGTAGGTTCTGACATGAAGAATCAAATTGAACAATTA
GGCAAGAAATATAATATTAATCCTGTTAGCCTGCACGTTGGTAAACAAGAAGAGAAGTTG
AGCTCCTTGGTGGCAACACAGGATCTTGTCATCAGCTTATTGCCTTATGTATTGCATCCT
CTTGTGGCCAAGGCATGCATCGCAAGCAAAGTTAACATGATCACTGCAAGCTACATCACC
CCAGCGCTAAAAGAATTAGAAAAGAGTGTGGAAGATGCTGGCATCACAGTCATTGGTGAA
TTGGGATTGGACCCTGGTCTTGATCATATGTTGGCAATGGAAACAATAGATAAGGCCAAA
GAAGTGGGAGCCACGATTGAATCTTATGTTTCCTACTGCGGTGGCCTTCCAGCTCCTGAA
TGTTCAGACAATCCTTTGAGATACAAATTTAGCTGGAGTCCAGTGGGAGTTCTGATGAAC
ATAATGCAGCCCGCTACCTACCTGCTCAACGGAAAGGTTGTGAATGCTGTAGGAGGTGTC
TCCTTTCTGGATTCAGTCACTCCCATGGATTATTTCCCTGGATTAAATTTGGAAGGTTAT
CCTAACAGAGACAGTACGAAGTATGCTGAGATTTATGGCATTCCATCTGCTCACACTTTA
TTACGAGGGACACTGAGGTACAAGGGGTATGCCAAAGCTTTGAGTGGATTTGTGAAGTTG
GGTCTCATAAACAGAGATGCGTTTCCTGCCCTTCAACCTGATGCCAATCCGCTCACCTGG
AAAGAACTCCTCTGTGATCTAGTTGGGATTTCATCCTCTTCCAAATGTGATGTGCTTAAG
GAAGCTGTCTTTAAGAAACTGGGAGGAGACACAACCCAGTTGGAGGCTCTCGAATGGTTA
GGGCTACTCGGGGATGAACAAGTCCCTCAGGCCGAGTCTCTCGTGGATGCCCTCTCCAAG
CATCTGGCCGTGAAACTTTCCTATGGTCCTGGAGAGAAAGATATGATTGTGATGAGAGAC
AGCTTTGGAATCAGACATCCTTCTGGACATTTGGAAAATAAAACTATTGATCTTGTGGTT
TATGGGGATGTCAATGGTTTTTCAGCCATGGCTAAAACTGTGGGGTTACCCACTGCTATG
GCAGCCAAGATGTTACTTGATGGTGAAATTCAAGCTAAAGGCCTGATGGGACCCTTTTCA
AAGGAGATCTATGGACCAATATTGGAGCGAATTAAAGCAGAAGGCATTATGTATACTACA
CAGAGCACAATCAAACTATAA
Enzyme 16 GenBank Gene ID BC153851 Link Image
Enzyme 16 GeneCard ID AASS Link Image
Enzyme 16 GenAtlas ID Not Available
Enzyme 16 HGNC ID Not Available
Enzyme 16 Chromosome Location Chromosome:7
Enzyme 16 Locus 7q31.3
Enzyme 16 SNPs SNPJam Report Link Image
Enzyme 16 General References Not Available
Enzyme 16 Metabolite References Not Available
Enzyme 17 [top]
Enzyme 17 ID 632
Enzyme 17 Name Probable saccharopine dehydrogenase
Enzyme 17 Synonyms Not Available
Enzyme 17 Gene Name SCCPDH
Enzyme 17 Protein Sequence >Probable saccharopine dehydrogenase
MATQQRPFHLVVFGASGFTGQFVTEEVAREQVSPERTSHLPWAVAGRSREKLLRVLERAA
MKLGRPTLSSEVGIIICDITNPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGTSC
IDISGEPQFLELMYWKYHEKAAEKGVYIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESF
LTISSGPEGLCVHDGTWKSAVYGFGDKSNLKKLRNESDMKPVPIVGPKLKRRWPISYCRE
LNSYSIPFLGADVSVVKRTQRYLHENLEQSPVQYAAYINVGGITSVIKLMFAGLFFLFFV
RFGIGRQLLIKFTWLFSFGYFSKQGPTQKQIDASSFTMTFFGQGFSQGVSPVKNKPNIRI
CTQVKGPEAGYVSTSIAMVQAAMILLNDASDLPKAGGVFTPGAAFSRTKLIDRLNEHGIE
FSVISSTEV
Enzyme 17 Number of Residues 429
Enzyme 17 Molecular Weight 47319.2
Enzyme 17 Theoretical pI 9.23
Enzyme 17 GO Classification
Function
Process
Component
Enzyme 17 General Function Involved in binding
Enzyme 17 Specific Function N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD(+) + H(2)O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADH
Enzyme 17 Pathways
  • Amino-acid degradation
  • L-lysine degradation via saccharopine pathway
  • glutaryl-CoA from L-lysine:step 2/6
Enzyme 17 Reactions Not Available
Enzyme 17 Pfam Domain Function
Enzyme 17 Signals
  • None
Enzyme 17 Transmembrane Regions
  • None
Enzyme 17 Essentiality Not Available
Enzyme 17 GenBank ID Protein 74354153 Link Image
Enzyme 17 UniProtKB/Swiss-Prot ID Q3T067 Link Image
Enzyme 17 UniProtKB/Swiss-Prot Entry Name SCPDH_BOVIN Link Image
Enzyme 17 PDB ID Not Available
Enzyme 17 Cellular Location Not Available
Enzyme 17 Gene Sequence >1290 bp
ATGGCGACCCAGCAGAGGCCTTTTCACCTGGTGGTGTTCGGCGCCTCTGGCTTTACCGGC
CAGTTCGTGACCGAGGAGGTGGCGCGGGAGCAGGTGTCCCCGGAGCGGACTTCCCATCTG
CCCTGGGCCGTGGCGGGCCGTTCCCGGGAGAAGCTGCTGCGAGTGCTGGAGAGGGCTGCC
ATGAAGCTGGGAAGACCGACACTGTCATCTGAAGTTGGAATAATAATTTGTGATATCACT
AATCCAGCCTCACTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAACTGTGTAGGC
CCATACCGATTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAACTAGCTGT
ATTGACATCTCTGGAGAACCTCAGTTTCTGGAACTAATGTATTGGAAGTATCATGAGAAA
GCTGCAGAAAAGGGGGTTTATATCATTGGAAGCAGTGGCTTTGACTCCATTCCAGCAGAT
CTGGGAGTAATATATACCAGAAATAAAATGAATGGTACACTGACTGCTGTGGAAAGTTTC
CTGACCATATCTTCAGGACCTGAGGGGTTGTGTGTTCATGATGGTACCTGGAAGTCAGCA
GTTTATGGTTTTGGAGATAAGAGTAATTTGAAAAAGCTACGAAATGAGTCAGATATGAAG
CCTGTCCCAATTGTTGGACCAAAATTGAAAAGAAGGTGGCCAATTTCTTACTGCAGAGAA
CTCAACAGTTATTCCATTCCTTTCTTGGGAGCAGATGTGTCTGTTGTGAAGCGGACTCAG
CGTTACTTGCATGAAAATTTAGAGCAGTCACCTGTTCAGTATGCTGCTTATATAAATGTG
GGAGGCATCACTTCTGTTATTAAGCTGATGTTTGCTGGACTCTTCTTTTTATTCTTTGTG
AGGTTTGGCATCGGAAGGCAACTTCTCATAAAATTCACATGGCTCTTCTCCTTTGGTTAT
TTTTCAAAACAAGGTCCAACACAAAAACAGATTGACGCTTCCTCATTTACGATGACATTT
TTTGGTCAAGGGTTCAGCCAAGGCGTCTCCCCTGTTAAGAACAAACCAAACATCAGAATT
TGTACTCAGGTGAAAGGACCAGAAGCTGGCTATGTATCTACCTCCATAGCCATGGTCCAG
GCAGCCATGATTCTTTTAAATGATGCCTCTGATCTTCCTAAGGCGGGTGGAGTCTTCACG
CCCGGAGCAGCTTTCTCCAGAACAAAGTTGATTGACAGACTCAATGAACATGGCATTGAA
TTTAGTGTCATTAGCAGCACTGAAGTCTAA
Enzyme 17 GenBank Gene ID BC102545 Link Image
Enzyme 17 GeneCard ID SCCPDH Link Image
Enzyme 17 GenAtlas ID Not Available
Enzyme 17 HGNC ID Not Available
Enzyme 17 Chromosome Location Chromosome:1
Enzyme 17 Locus 1q44
Enzyme 17 SNPs SNPJam Report Link Image
Enzyme 17 General References Not Available
Enzyme 17 Metabolite References Not Available
Enzyme 18 [top]
Enzyme 18 ID 827
Enzyme 18 Name Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2
Enzyme 18 Synonyms
  1. Glutamine:fructose 6 phosphate amidotransferase 2
  2. GFAT 2
  3. GFAT2
  4. D-fructose-6-phosphate amidotransferase 2
  5. Hexosephosphate aminotransferase 2
Enzyme 18 Gene Name GFPT2
Enzyme 18 Protein Sequence >Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2
MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNNEVKERHIQLVKKR
GNVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHN
GIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEG
AFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTRNIENVKNICKTRMK
RLDSSTCLHAVGNKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRLAS
DDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDH
LKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFF
ISQSGETADTLLALRYCKDRRALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYT
SQFISLVMFGLMMSEDRISLQNRRREIIHGLKSLPELIKEVLSLDEKIHDLALELYTQRS
LLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCF
AKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFH
LAVLRGYDVDFPRNLAKSVTVE
Enzyme 18 Number of Residues 682
Enzyme 18 Molecular Weight 77080.1
Enzyme 18 Theoretical pI 7.72
Enzyme 18 GO Classification
Function
Process
Component
Enzyme 18 General Function Cell wall/membrane/envelope biogenesis
Enzyme 18 Specific Function Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins
Enzyme 18 Pathways
  • Nucleotide-sugar biosynthesis
  • UDP-N-acetyl-alpha-D- glucosamine biosynthesis
  • alpha-D-glucosamine 6-phosphate from D- fructose 6-phosphate:step 1/1
Enzyme 18 Reactions Not Available
Enzyme 18 Pfam Domain Function
Enzyme 18 Signals
  • None
Enzyme 18 Transmembrane Regions
  • None
Enzyme 18 Essentiality Not Available
Enzyme 18 GenBank ID Protein 115304901 Link Image
Enzyme 18 UniProtKB/Swiss-Prot ID Q08DQ2 Link Image
Enzyme 18 UniProtKB/Swiss-Prot Entry Name GFPT2_BOVIN Link Image
Enzyme 18 PDB ID Not Available
Enzyme 18 Cellular Location Not Available
Enzyme 18 Gene Sequence >2049 bp
ATGTGCGGAATCTTTGCCTACATGAATTACAGAGTCCCCCGGACAAGGAAGGAGATTTTT
GAAACCCTCATCAAGGGCCTGCAGCGGCTTGAGTACAGAGGCTATGACTCAGCAGGTGTG
GCAATTGATGGAAATAATAATGAAGTCAAAGAAAGGCATATCCAGCTCGTCAAGAAAAGA
GGAAATGTCAAAGCTCTTGATGAAGAACTTTACAAACAAGACAGCATGGACTTAAAAGTG
GAGTTTGAGACCCACTTTGGCATTGCCCACACACGGTGGGCCACTCACGGGGTCCCCAGT
GCTGTCAACAGCCACCCGCAGCGCTCAGACAAGGGCAACGAATTCGTTGTCATCCATAAT
GGGATCATCACAAATTACAAAGACCTGAGGAAATTTCTGGAAAGCAAAGGCTATGAGTTT
GAGTCAGAAACAGATACAGAAACCATTGCCAAGCTGATTAAATATGTGTTCGACAACAGA
GAAACCGAGGACATTACATTTTCAACACTGGTGGAGAGAGTCATTCAGCAGCTGGAAGGC
GCATTTGCCTTGGTTTTCAAGAGCATCCACTACCCTGGAGAAGCCGTGGCCACAAGGAGA
GGCAGTCCCCTACTCATCGGAGTAAGGAGCAAATACAAACTCTCCACAGAACAGATCCCC
GTCTTATATAGGACACGCAATATTGAGAATGTGAAGAATATCTGTAAAACAAGGATGAAG
AGGCTGGACAGCTCGACCTGCCTTCACGCTGTGGGCAATAAAGCAGTGGAATTCTTTTTT
GCTTCTGATGCAAGTGCTATCATAGAGCACACCAACCGGGTCATCTTCCTTGAGGATGAT
GACATTGCCGCAGTGGCTGATGGGAAACTCTCTATTCACCGGGTCAAGCGTTTGGCTAGT
GATGACCCATCTCGAGCCATCCAGACCTTGCAGATGGAATTGCAGCAAATCATGAAAGGT
AACTTCAGTGCATTTATGCAAAAGGAGATATTTGAACAGCCAGAATCCGTTTTCAATACC
ATGAGAGGTCGAGTGAATTTTGAGACCAACACAGTGCTCCTGGGTGGCTTGAAAGACCAC
TTGAAGGAGATCAGACGATGCCGACGGCTCATTGTGATTGGCTGTGGGACCAGCTACCAC
GCCGCTGTGGCCACGCGGCAAGTTTTGGAGGAACTGACCGAGCTCCCCGTGATGGTTGAA
CTTGCTAGTGATTTTCTGGACAGGAACACACCTGTGTTCAGGGATGACGTTTGCTTTTTC
ATAAGCCAGTCAGGGGAGACTGCAGACACCCTCCTGGCACTGCGCTACTGCAAGGACCGC
CGAGCTCTGACCGTGGGCGTCACCAACACCGTGGGCAGCTCCATCTCCCGCGAGACGGAC
TGCGGCGTCCACATCAACGCAGGGCCGGAGATCGGTGTGGCCAGCACCAAGGCTTACACC
AGTCAGTTCATCTCCTTGGTGATGTTTGGTTTGATGATGTCTGAAGACCGCATTTCACTG
CAAAACAGAAGGCGAGAGATCATCCATGGCCTGAAATCTCTACCCGAGCTGATCAAGGAG
GTGCTGTCCCTGGATGAGAAGATCCACGACCTGGCCCTGGAGCTCTACACACAAAGGTCA
CTTCTGGTCATGGGGCGAGGCTACAACTATGCCACATGCCTGGAAGGAGCCCTGAAAATT
AAAGAGATAACCTACATGCACTCAGAAGGCATCCTGGCTGGAGAGTTGAAGCACGGCCCC
CTGGCGCTGATTGATAAGCAGATGCCTGTCATCATGGTCATCATGAAGGATCCTTGCTTT
GCCAAATGCCAGAACGCCCTGCAGCAGGTCACAGCGCGCCAGGGTCGCCCGATTATACTG
TGCTCCAAGGACGACACTGAAAGCTCCAAGTTTGCATATAAAACGATCGAGCTGCCCCAC
ACCGTAGACTGCCTGCAGGGCATCCTGAGTGTGATTCCACTGCAGCTCCTCTCCTTCCAC
CTGGCTGTACTCCGAGGATATGACGTTGACTTCCCCAGAAATCTGGCCAAGTCTGTAACC
GTGGAATGA
Enzyme 18 GenBank Gene ID BC123624 Link Image
Enzyme 18 GeneCard ID GFPT2 Link Image
Enzyme 18 GenAtlas ID Not Available
Enzyme 18 HGNC ID Not Available
Enzyme 18 Chromosome Location Chromosome:5
Enzyme 18 Locus 5q34-q35
Enzyme 18 SNPs SNPJam Report Link Image
Enzyme 18 General References Not Available
Enzyme 18 Metabolite References Not Available
Enzyme 19 [top]
Enzyme 19 ID 850
Enzyme 19 Name Glutamyl-tRNA(Gln) amidotransferase subunit A homolog
Enzyme 19 Synonyms
  1. Glutaminyl-tRNA synthase-like protein 1
Enzyme 19 Gene Name QRSL1
Enzyme 19 Protein Sequence >Glutamyl-tRNA(Gln) amidotransferase subunit A homolog
MLGRTLREVSVELKQGQITPTELCQRCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYK
KGHSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYVPPYNATVVQKLLDQGALLMGKTN
LDEFAMGSGSTDGIFGPVKNPWSYSKQYREKRKQNSHSENEDSNWLITGGSSGGSAAAVS
AFTCFAALGSDTGGSTRNPAAHCGVVGLKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDA
ATVLGVLAGHDPKDSTTIQDPVKPFTLPSLTDVSKLCIGIPKEYLTPELSSEVQSLWSKA
ANLFESEGAKVTEVSLPHTSYSIVCYHVLCTSEVASNMARFDGLEYGHRCDSDVSTEAMY
AATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNVFNSGVDVLLTP
TTLSEAVPYTEFIKEDNRTRSAQDDIFTQAVNMAGLPAVSVPVALSSQGLPIGLQFIGRA
FCDQQLLIVAKWFEKQVQFPVIQLQELMDDCSSVFENEKLASVSLK
Enzyme 19 Number of Residues 526
Enzyme 19 Molecular Weight 57299.6
Enzyme 19 Theoretical pI 5.72
Enzyme 19 GO Classification
Function
Process
Component
Enzyme 19 General Function Translation, ribosomal structure and biogenesis
Enzyme 19 Specific Function ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate
Enzyme 19 Pathways Not Available
Enzyme 19 Reactions Not Available
Enzyme 19 Pfam Domain Function
Enzyme 19 Signals
  • None
Enzyme 19 Transmembrane Regions
  • None
Enzyme 19 Essentiality Not Available
Enzyme 19 GenBank ID Protein 88954303 Link Image
Enzyme 19 UniProtKB/Swiss-Prot ID Q29RP9 Link Image
Enzyme 19 UniProtKB/Swiss-Prot Entry Name QRSL1_BOVIN Link Image
Enzyme 19 PDB ID Not Available
Enzyme 19 Cellular Location Not Available
Enzyme 19 Gene Sequence >1581 bp
ATGTTGGGCCGGACCCTGCGAGAAGTTTCTGTGGAACTGAAACAAGGCCAGATCACGCCA
ACTGAGCTCTGTCAAAGATGTCTCTCCCTTATCAAGAAGACTAAGTTTCTAAATGCATAC
ATTACTGTATCAGAAGAAGTGGCCTTAAAGCAAGCTGAAGAATCAGAGAAAAGATATAAG
AAAGGTCACTCACTGGGAGATTTAGATGGAATTCCTATTGCAGTAAAAGATAACTTTAGT
ACATCCGGCATTGAGACAACCTGTGCATCAAACATGCTGAAAGGTTATGTACCACCTTAT
AATGCCACAGTAGTTCAGAAGTTGTTGGATCAGGGAGCTCTGCTAATGGGAAAAACAAAC
TTAGATGAGTTTGCTATGGGATCTGGAAGCACAGATGGCATATTTGGACCAGTTAAAAAC
CCGTGGAGTTATTCAAAACAATATAGAGAAAAGAGGAAGCAAAACTCTCACAGTGAGAAT
GAGGATTCAAATTGGCTTATAACCGGAGGAAGCTCAGGAGGAAGTGCAGCGGCCGTGTCA
GCGTTCACGTGCTTTGCGGCTTTAGGATCAGATACGGGAGGATCAACCAGAAATCCAGCT
GCCCACTGCGGGGTTGTTGGTTTAAAACCAAGCTATGGCCTAGTTTCTCGTCATGGTCTC
ATTCCCCTGGTGAATTCAATGGATGTGCCAGGAATCTTAACCAGATGTGTGGATGATGCA
GCCACTGTGTTGGGTGTACTAGCTGGGCATGATCCCAAAGATTCTACCACAATTCAAGAT
CCTGTTAAACCATTTACGCTTCCCAGTTTGACAGATGTGAGCAAACTATGTATAGGAATT
CCAAAGGAGTATCTTACGCCAGAATTGTCAAGTGAAGTACAATCTCTTTGGTCCAAAGCT
GCTAATCTCTTTGAGTCTGAGGGGGCCAAAGTAACTGAAGTCTCCCTGCCCCATACCAGC
TACTCAATTGTGTGCTACCACGTATTGTGCACGTCGGAAGTGGCATCGAATATGGCCAGA
TTTGATGGGCTAGAATATGGTCACAGATGTGATAGTGATGTGTCTACTGAAGCCATGTAT
GCTGCAACCAGGCGAGAAGGGTTCAATGATGTGGTGAGAGGGAGAATCCTCTCAGGAAAC
TTTTTCCTATTAAAAGAAAATTATGAGAATTATTTTGTCAAAGCACAGAAAGTGAGACGG
CTCATTGCTAATGATTTTGTTAATGTTTTTAACTCTGGAGTGGACGTGCTGCTAACTCCC
ACGACCTTGAGTGAGGCAGTGCCGTACACAGAGTTCATCAAGGAAGACAACAGGACGCGC
AGCGCCCAAGACGACATCTTTACACAGGCCGTGAATATGGCAGGACTGCCAGCAGTGAGT
GTCCCTGTGGCCCTCTCAAGCCAAGGGTTGCCAATAGGACTGCAGTTTATTGGACGTGCA
TTTTGTGACCAGCAGCTTCTTATAGTTGCCAAATGGTTTGAAAAACAAGTCCAGTTTCCT
GTTATTCAACTTCAAGAACTAATGGATGATTGTTCATCAGTCTTTGAAAATGAAAAGTTG
GCTTCTGTTTCTCTAAAATAG
Enzyme 19 GenBank Gene ID BC114078 Link Image
Enzyme 19 GeneCard ID QRSL1 Link Image
Enzyme 19 GenAtlas ID Not Available
Enzyme 19 HGNC ID Not Available
Enzyme 19 Chromosome Location Chromosome:6
Enzyme 19 Locus 6q21
Enzyme 19 SNPs SNPJam Report Link Image
Enzyme 19 General References Not Available
Enzyme 19 Metabolite References Not Available
Enzyme 20 [top]
Enzyme 20 ID 852
Enzyme 20 Name Glutamine-dependent NAD(+) synthetase
Enzyme 20 Synonyms
  1. NAD(+) synthase [glutamine-hydrolyzing]
  2. NAD(+) synthetase 1
Enzyme 20 Gene Name NADSYN1
Enzyme 20 Protein Sequence >Glutamine-dependent NAD(+) synthetase
MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKHRGARYRLGPELEICGYGCWDHYYES
DTLLHSLQVLAALLESPVTQDIICDVGMPVMHRNVRYNCRVIFLNRKILLIRPKMALANE
GNYRELRWFTPWSRSRQTEEYFLPRMLQDLTKQETVPFGDAVLSTWDTCIGSEVCEELWT
PHSPHVDMGLDGVEIFTNASGSHHVLRKAHARVDLVTMATTKNGGIYLLANQKGCDGDRL
YYDGCALIAMNGSIFAQGSQFSLDDVEVLTATLDLEDIRSYRAEISSRNLAASRVSPYPR
VKVDFALSCHEDLLEPVSEPIEWKYHSPAEEISLGPACWLWDFLRRSRQAGFFLPLSGGV
DSAATACLVYSMCHQVCEAVKRGNLEVLADVRTIVNQLSYTPQDPRELCGRVLTTCYMAS
ENSSQETCDRARELAQQIGSHHIGLHIDPVVKALVGLFSLVTGASPRFAVHGGSDRENLA
LQNVQARVRMVIAYLFAQLSLWSRGAPGGLLVLGSANVDESLLGYLTKYDCSSADINPIG
GISKTDLRAFVQLCVERFQLPALQSILAAPATAELEPLAHGRVSQTDEEDMGMTYAELSV
YGRLRKVAKTGPYSMFCKLLDMWRDTCSPRQVADKVKCFFSKYSMNRHKMTTLTPAYHAE
SYSPDDNRFDLRPFLYNTRWPWQFRCIENQVLQLEGRQRQELDGVD
Enzyme 20 Number of Residues 706
Enzyme 20 Molecular Weight 79398.9
Enzyme 20 Theoretical pI 6.46
Enzyme 20 GO Classification
Function
Process
Component
Enzyme 20 General Function Coenzyme transport and metabolism
Enzyme 20 Specific Function ATP + deamido-NAD(+) + L-glutamine + H(2)O = AMP + diphosphate + NAD(+) + L-glutamate
Enzyme 20 Pathways
  • Cofactor biosynthesis
  • NAD(+) biosynthesis
  • NAD(+) from deamido-NAD(+) (L-Gln route):step 1/1
Enzyme 20 Reactions Not Available
Enzyme 20 Pfam Domain Function
Enzyme 20 Signals
  • None
Enzyme 20 Transmembrane Regions
  • None
Enzyme 20 Essentiality Not Available
Enzyme 20 GenBank ID Protein 73587273 Link Image
Enzyme 20 UniProtKB/Swiss-Prot ID Q3ZBF0 Link Image
Enzyme 20 UniProtKB/Swiss-Prot Entry Name NADE1_BOVIN Link Image
Enzyme 20 PDB ID Not Available
Enzyme 20 Cellular Location Not Available
Enzyme 20 Gene Sequence >2121 bp
ATGGGGCGAAAGGTGACCGTGGCCACCTGTGCGCTCAACCAGTGGGCCCTGGACTTTGAG
GGCAATTTGCAAAGGATTTTAAAAAGTATTGAAATTGCCAAACACAGAGGAGCAAGATAC
AGGCTTGGACCAGAACTGGAAATCTGTGGCTACGGCTGTTGGGATCATTATTACGAGTCG
GACACCCTCCTGCATTCGCTCCAGGTCCTGGCGGCCCTTTTGGAGTCTCCGGTCACTCAG
GATATCATCTGCGACGTGGGGATGCCCGTGATGCACCGAAACGTCCGCTATAACTGCAGG
GTGATATTCCTCAACAGGAAGATCCTGCTCATCAGACCCAAGATGGCCTTGGCGAATGAG
GGCAACTACCGAGAGTTGCGCTGGTTCACGCCATGGTCCAGGAGCCGGCAAACAGAGGAG
TATTTTCTCCCCCGGATGTTACAGGACCTGACGAAGCAGGAAACTGTGCCCTTTGGGGAT
GCCGTCCTCTCCACATGGGACACCTGTATCGGGAGTGAGGTCTGTGAGGAGCTCTGGACG
CCCCACAGCCCACACGTGGACATGGGCCTGGACGGCGTGGAGATCTTCACCAACGCCTCG
GGTAGCCATCACGTGCTGCGCAAAGCCCACGCCCGGGTGGACCTGGTGACCATGGCTACC
ACCAAGAACGGCGGGATCTACTTGCTGGCCAATCAGAAGGGCTGCGATGGGGACCGGCTG
TATTACGACGGCTGTGCTCTCATAGCCATGAACGGCAGCATCTTTGCCCAGGGGTCCCAG
TTCTCTCTGGATGACGTGGAAGTGCTCACTGCCACGTTGGATTTGGAGGACATCAGAAGC
TACAGGGCGGAGATTTCATCTCGAAACCTGGCGGCCAGCAGGGTGAGCCCCTACCCCCGC
GTGAAGGTGGATTTCGCCCTCTCCTGCCATGAAGACCTGCTGGAGCCTGTGTCTGAGCCT
ATCGAGTGGAAATACCACAGTCCCGCCGAGGAGATCAGCCTGGGACCCGCGTGCTGGCTC
TGGGACTTCTTAAGACGCAGCCGACAGGCAGGGTTCTTCCTTCCCCTGAGCGGCGGGGTG
GACAGCGCGGCCACCGCCTGCCTGGTCTACTCCATGTGCCACCAGGTCTGCGAGGCTGTG
AAGCGTGGAAATCTGGAGGTGCTGGCTGATGTCCGAACCATCGTGAACCAGCTCAGCTAC
ACCCCCCAGGACCCCCGGGAGCTCTGCGGCCGCGTCCTGACCACCTGCTACATGGCCAGC
GAGAACTCCTCCCAGGAGACCTGCGACAGGGCCCGAGAGCTGGCCCAGCAGATTGGAAGC
CACCACATCGGTCTCCACATCGACCCAGTGGTCAAGGCCCTCGTGGGCCTCTTCAGCCTG
GTGACGGGTGCGAGCCCTCGGTTTGCGGTTCACGGAGGGAGCGACCGGGAGAACCTGGCT
CTGCAGAACGTCCAGGCGCGGGTGAGGATGGTCATCGCCTACCTCTTCGCTCAGCTGAGC
CTCTGGTCTCGCGGTGCCCCCGGCGGGCTTCTCGTGCTCGGATCCGCCAATGTGGACGAG
AGCCTCCTTGGCTACCTGACCAAGTACGACTGCTCCAGCGCTGACATCAACCCCATCGGC
GGGATCAGCAAGACGGACCTGAGAGCCTTCGTCCAGCTCTGCGTGGAGCGCTTCCAGCTT
CCTGCCCTGCAGAGCATCCTGGCAGCACCGGCCACAGCTGAGCTGGAGCCCCTGGCCCAC
GGACGGGTGTCCCAGACCGATGAGGAAGACATGGGGATGACATATGCGGAGCTGTCCGTC
TACGGGAGGCTCCGGAAGGTCGCCAAGACAGGCCCCTACAGCATGTTCTGCAAACTCCTC
GACATGTGGAGGGATACCTGCTCGCCCCGACAGGTGGCTGACAAAGTGAAGTGCTTTTTC
TCCAAGTATTCCATGAACAGACACAAGATGACCACACTGACCCCCGCATACCACGCCGAG
AGCTACAGCCCGGACGACAACAGGTTCGACCTGCGGCCATTTCTGTATAACACCCGCTGG
CCCTGGCAGTTCCGCTGCATCGAAAACCAGGTCCTCCAGCTGGAGGGGAGACAGCGGCAG
GAGCTAGACGGCGTGGACTGA
Enzyme 20 GenBank Gene ID BC103388 Link Image
Enzyme 20 GeneCard ID NADSYN1 Link Image
Enzyme 20 GenAtlas ID Not Available
Enzyme 20 HGNC ID Not Available
Enzyme 20 Chromosome Location Chromosome:1
Enzyme 20 Locus 11q13.4
Enzyme 20 SNPs SNPJam Report Link Image
Enzyme 20 General References Not Available
Enzyme 20 Metabolite References Not Available
Enzyme 21 [top]
Enzyme 21 ID 855
Enzyme 21 Name Phosphoserine aminotransferase
Enzyme 21 Synonyms Not Available
Enzyme 21 Gene Name PSAT1
Enzyme 21 Protein Sequence >Phosphoserine aminotransferase
MDSLMPVVNFGPGPAKLPRSVLLEMQKELLDYKGIGISVLEMSHRSSDFSKIINKTETLV
RELLAIPDNYKVIFVQGGGCGQFSAVPLNLIGLKAGRCADYVVTGSWSAKAAEEAKKFGT
VNIVHPKLGSYTKIPDPSTWTLNPDASYVYYCANETVHGVEFDFIPDVKGAVLVCDMSSN
FLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIIRDDLLGFALKECPSVLDYKVQAGNNSLY
NTPPCFSIYVMGLVLEWIKNNGGAAAMEKLSSIKSQMIYDIIDNSQGFYVCPVEPQNRSK
MNIPFRIGNTKGDDALEKRFLDKALELNMISLKGHRSVGGIRVSLYNAVTVEDVQKLAAF
MKNFLEMHQL
Enzyme 21 Number of Residues 370
Enzyme 21 Molecular Weight 40528.6
Enzyme 21 Theoretical pI 7.75
Enzyme 21 GO Classification
Function
Process
Component
Enzyme 21 General Function Coenzyme transport and metabolism
Enzyme 21 Specific Function O-phospho-L-serine + 2-oxoglutarate = 3- phosphonooxypyruvate + L-glutamate
Enzyme 21 Pathways
  • Amino-acid biosynthesis
  • L-serine biosynthesis
  • L-serine from 3-phospho-D-glyceric acid:step 2/3
Enzyme 21 Reactions Not Available
Enzyme 21 Pfam Domain Function
Enzyme 21 Signals
  • None
Enzyme 21 Transmembrane Regions
  • None
Enzyme 21 Essentiality Not Available
Enzyme 21 GenBank ID Protein 151556105 Link Image
Enzyme 21 UniProtKB/Swiss-Prot ID A6QR28 Link Image
Enzyme 21 UniProtKB/Swiss-Prot Entry Name A6QR28_BOVIN Link Image
Enzyme 21 PDB ID Not Available
Enzyme 21 Cellular Location Not Available
Enzyme 21 Gene Sequence >1113 bp
ATGGACTCCCTGATGCCGGTGGTCAACTTCGGACCCGGGCCTGCCAAGCTGCCGCGCTCC
GTGTTGCTAGAGATGCAAAAAGAATTATTAGACTACAAAGGAATTGGGATTAGTGTTCTT
GAAATGAGCCACAGGTCATCAGATTTCTCTAAGATTATCAATAAGACAGAGACCCTTGTA
CGGGAATTGTTAGCCATTCCAGACAACTACAAAGTGATTTTTGTACAAGGAGGTGGGTGT
GGTCAGTTCAGTGCTGTCCCCTTAAACCTGATTGGCCTGAAAGCAGGAAGATGTGCTGAC
TATGTGGTGACAGGATCCTGGTCAGCTAAGGCTGCAGAAGAAGCCAAGAAGTTTGGAACT
GTGAATATCGTCCACCCCAAACTTGGGAGTTACACGAAAATTCCAGATCCGAGCACCTGG
ACCCTCAACCCGGATGCCTCCTATGTGTATTACTGCGCCAATGAGACTGTGCACGGAGTG
GAGTTTGACTTTATCCCTGATGTCAAGGGAGCAGTGCTGGTCTGCGACATGTCCTCAAAC
TTCCTGTCCAGGCCAGTGGATGTTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAG
AATGTTGGCTCTGCAGGGGTCACGGTGGTGATCATCCGAGATGACCTGCTGGGGTTTGCC
CTCAAAGAGTGCCCCTCGGTCCTGGATTACAAAGTGCAGGCTGGAAATAACTCCCTGTAC
AACACACCTCCCTGTTTCAGCATCTATGTCATGGGCTTGGTCCTGGAGTGGATTAAGAAC
AACGGCGGGGCAGCAGCCATGGAGAAGCTTAGCTCCATCAAATCGCAAATGATTTATGAT
ATTATTGATAATTCACAAGGATTCTATGTATGTCCAGTGGAGCCCCAGAATAGAAGCAAG
ATGAATATTCCATTCCGCATTGGCAACACCAAAGGAGACGATGCTTTAGAAAAAAGATTT
CTTGACAAAGCTCTTGAACTCAATATGATCTCCTTGAAAGGGCATAGGTCCGTGGGAGGC
ATCCGGGTCTCTCTGTACAATGCTGTCACTGTCGAAGACGTCCAGAAGCTGGCAGCCTTC
ATGAAGAATTTTTTGGAGATGCACCAGCTATGA
Enzyme 21 GenBank Gene ID BC150088 Link Image
Enzyme 21 GeneCard ID PSAT1 Link Image
Enzyme 21 GenAtlas ID Not Available
Enzyme 21 HGNC ID Not Available
Enzyme 21 Chromosome Location Chromosome:9
Enzyme 21 Locus 9q21.2
Enzyme 21 SNPs SNPJam Report Link Image
Enzyme 21 General References Not Available
Enzyme 21 Metabolite References Not Available
Enzyme 22 [top]
Enzyme 22 ID 856
Enzyme 22 Name Glutamate dehydrogenase 1, mitochondrial
Enzyme 22 Synonyms
  1. GDH
Enzyme 22 Gene Name GLUD1
Enzyme 22 Protein Sequence >Glutamate dehydrogenase 1, mitochondrial
MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLVPPARRHYSEAAADR
EDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRETEEQKRNRVRSILRIIKPCNHVLSLSF
PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG
GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGVDVPAPDMSTGEREMSWIADTY
ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG
DKTFVVQGFGNVGLHSMRYLHRFGAKCITVGESDGSIWNPDGIDPKELEDFKLQHGTILG
FPKAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER
NIMVIPDLYLNAGGVTVSYFEWLNNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK
HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV
NAIEKVFRVYNEAGVTFT
Enzyme 22 Number of Residues 558
Enzyme 22 Molecular Weight 61511.4
Enzyme 22 Theoretical pI 7.67
Enzyme 22 GO Classification
Function
Process
Component
Enzyme 22 General Function Replication, recombination and repair
Enzyme 22 Specific Function May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate
Enzyme 22 Pathways Not Available
Enzyme 22 Reactions Not Available
Enzyme 22 Pfam Domain Function
Enzyme 22 Signals
  • None
Enzyme 22 Transmembrane Regions
  • None
Enzyme 22 Essentiality Not Available
Enzyme 22 GenBank ID Protein 23306688 Link Image
Enzyme 22 UniProtKB/Swiss-Prot ID P00366 Link Image
Enzyme 22 UniProtKB/Swiss-Prot Entry Name DHE3_BOVIN Link Image
Enzyme 22 PDB ID 1L1F Link Image
Enzyme 22 PDB File Show
Enzyme 22 3D Structure
Enzyme 22 Cellular Location Not Available
Enzyme 22 Gene Sequence Not Available
Enzyme 22 GenBank Gene ID AY138843 Link Image
Enzyme 22 GeneCard ID GLUD1 Link Image
Enzyme 22 GenAtlas ID Not Available
Enzyme 22 HGNC ID Not Available
Enzyme 22 Chromosome Location Chromosome:1
Enzyme 22 Locus 10q23.3
Enzyme 22 SNPs SNPJam Report Link Image
Enzyme 22 General References
  1. [PubMed Link Image]
Enzyme 22 Metabolite References Not Available
Enzyme 23 [top]
Enzyme 23 ID 857
Enzyme 23 Name 5-oxoprolinase
Enzyme 23 Synonyms
  1. 5-oxo-L-prolinase
  2. 5-OPase
  3. Pyroglutamase
Enzyme 23 Gene Name OPLAH
Enzyme 23 Protein Sequence >5-oxoprolinase
MGGPEGRFHFAIDRGGTFTDVFAQCPGGHVRVLKLLSEDPANYVDAPTEGIRRILEQEGG
VLLPRDRPLDTSRIASIRMGTTVATNALLEQQGERVALLVTRGFRDLLHVCTQARAXLFD
LAVPMPETLYEEVLEVDERVVLYRGXPGAGTPVKGCTGDLLEVQQPVDLGGLRWKLEGLL
SRGIRSLAVVLMHSYTWAQHEQQVGALARELGFTHVSLSSEAMPMVRIVPRGHTACADAY
LTPTIQRYVQGFRRGFQGQLKDVQVLFMRSDGGLAPMDSFSGSRAVLSGPAGGVVGYSAT
TYRVEGGQPVIGFDMGGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRL
FFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGEDQPLSP
EASRKALEAVATEVNSFLTNGPCPASPLSLEEVAMGFVRVANEAMCRPIRALTQARGHDP
SAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLPYA
PETFAQLDQRLGRLEEQCVEALRAQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPASA
RSPRAGDFGAAFVERYMREFGFIIPERPVVVDDVRVRGTGSSSLRLEDVPKAHSGPPRVD
KMTQCYFEGGYQETPVYLLGELGCGHKLQGPCLIIDSNSTILVEPGCQAEVTETGDIRIS
VGAETASVVGTQLDPIHLTIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDG
GLVSNVPHIPVHLGAMQETVQFQIQQLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFW
PGQTRPVFYVASRGHHADIGGITPGSMPPHSTSLQQEGAVFLSFKLVHGGVFQEEAVTEA
LRAPGKIPGCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANA
ELAVRDMLRAFGTARQARGLPLEVSAEDHMDDGSPIRLRVQINMSQGSAVFDFSGSGPEV
FGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVRVVIPKGSILDPSPDAAVVGGNV
LTSQRVVDVILGAFGACAASQGCMNNVTLGNAHMGYYETVAGGAGAGPGWHGRSGVHSHM
TNTRITDPEILESRYPVILRRFELRLGSGGRGRFRGGDGIIRELLFREEALLSVLTERRA
FQPYGLMGGEPGARGLNLLIRKDGRTVNLGGKTSVPVYPGDVFCLHTPGGGGYGDPGDPA
PLPGSPLQPLAFPERGSVYEYRRAQEAV
Enzyme 23 Number of Residues 1288
Enzyme 23 Molecular Weight 137340.3
Enzyme 23 Theoretical pI 6.55
Enzyme 23 GO Classification
Function
Process
Component
Enzyme 23 General Function Amino acid transport and metabolism
Enzyme 23 Specific Function Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate
Enzyme 23 Pathways Not Available
Enzyme 23 Reactions Not Available
Enzyme 23 Pfam Domain Function
Enzyme 23 Signals
  • None
Enzyme 23 Transmembrane Regions
  • None
Enzyme 23 Essentiality Not Available
Enzyme 23 GenBank ID Protein 46020038 Link Image
Enzyme 23 UniProtKB/Swiss-Prot ID Q75WB5 Link Image
Enzyme 23 UniProtKB/Swiss-Prot Entry Name OPLA_BOVIN Link Image
Enzyme 23 PDB ID Not Available
Enzyme 23 Cellular Location Not Available
Enzyme 23 Gene Sequence >3867 bp
ATGGGTGGCCCGGAGGGCCGCTTCCATTTTGCCATCGACCGTGGAGGCACCTTCACAGAT
GTCTTTGCCCAGTGCCCAGGGGGGCACGTGAGGGTCCTAAAGCTGCTTTCAGAAGACCCT
GCCAACTATGTAGACGCCCCCACTGAAGGCATCCGCCGCATCCTGGAGCAGGAGGGGGGC
GTGCTGCTGCCGCGGGACCGGCCCCTGGACACCAGTCGCATCGCCAGCATCCGCATGGGC
ACCACGGTGGCGACCAATGCGCTGTTGGAACAACAGGGAGAGCGGGTGGCACTGCTGGTG
ACGCGCGGGTTCCGAGACCTGCTGCACGTGTGCACCCAGGCCCGCGCGGANCTCTTTGAC
CTGGCCGTGCCCATGCCCGAGACGCTGTACGAGGAGGTGCTGGAAGTGGACGAACGGGTG
GTGCTCTATCGAGGGGANCCGGGTGCTGGGACACCCGTGAAAGGCTGCACAGGGGACCTA
CTGGAAGTGCAGCAGCCTGTGGACCTGGGGGGCCTGCGATGGAAGCTGGAAGGTCTCCTG
TCCCGGGGCATCCGTAGCTTGGCCGTGGTGCTCATGCACTCGTACACGTGGGCCCAGCAC
GAGCAGCAGGTGGGCGCCCTGGCCCGGGAACTGGGCTTCACGCATGTGTCGCTGTCCTCG
GAGGCCATGCCCATGGTGCGCATTGTGCCCCGGGGGCACACGGCCTGTGCTGACGCCTAT
CTCACGCCCACCATCCAGCGCTACGTGCAGGGCTTCCGACGTGGCTTCCAGGGTCAGCTC
AAGGACGTGCAGGTGCTGTTCATGCGCTCCGACGGTGGGCTGGCGCCCATGGACTCCTTC
AGCGGCTCCCGCGCTGTGCTCTCCGGGCCTGCGGGGGGCGTGGTTGGTTACTCAGCCACC
ACCTACCGGGTGGAGGGCGGCCAGCCAGTCATCGGCTTTGACATGGGAGGCACGTCTACC
GACGTGAGCCGCTATGCTGGCGAGTTTGAGCATGTTTTCGAGGCCAGCACGGCTGGTGTC
ACCCTCCAGGCCCCCCAGCTGGATATCAACACTGTGGCAGCCGGTGGGGGCTCCCGCCTC
TTTTTCAGGTCGGGCCTCTTCGTGGTGGGGCCAGAGTCTGCGGGAGCCCACCCTGGCCCC
GCCTGCTACCGAAAAGGGGGCCCTGTGACAGTGACGGATGCTAATCTGGTCCTGGGTCGC
CTGCTGCCTGCCTCCTTCCCCTGCATTTTTGGGCCGGGAGAGGACCAGCCACTGTCCCCG
GAGGCGTCCCGAAAGGCCCTGGAGGCTGTGGCCACGGAGGTCAACAGCTTCCTGACCAAT
GGGCCTTGCCCGGCCTCCCCGCTGAGCCTGGAGGAGGTGGCCATGGGGTTTGTGCGTGTG
GCCAACGAGGCCATGTGTCGGCCCATCCGTGCACTCACGCAGGCACGAGGTCATGACCCC
TCGGCCCACGTGCTGGCCTGCTTTGGGGGAGCTGGTGGGCAGCATGCTTGTGCCATTGCC
CGGGCCCTGGGCATGGACACTGTGCACATTCACAGGCACAGTGGGCTGCTGTCGGCGCTG
GGGCTGGCCCTGGCTGATGTGGTGCATGAGGCGCAGGAGCCCTGCTCCCTGCCATATGCT
CCCGAGACCTTTGCGCAGCTGGACCAGAGGCTGGGCCGCCTGGAGGAGCAGTGTGTGGAG
GCCCTGCGGGCCCAGGGCTTCCCCAGGTCCCAGATCAGCACCGAGAGCTTCCTGCACCTG
CGCTACCAGGGCACGGACTGCGCCCTGATGGTGTCTGCCCACCAGCACCCGGCCAGTGCC
CGCTCACCCCGAGCTGGTGACTTTGGGGCAGCCTTTGTGGAGAGGTACATGAGGGAGTTC
GGCTTCATTATTCCCGAGCGGCCGGTGGTGGTGGATGACGTGCGGGTCAGGGGCACCGGC
AGCAGCAGCCTTCGCCTCGAGGACGTCCCAAAAGCCCATAGTGGGCCTCCCCGGGTAGAT
AAGATGACCCAGTGCTACTTTGAGGGGGGCTACCAGGAGACCCCTGTGTACCTGTTGGGA
GAGCTGGGCTGTGGGCACAAGCTTCAGGGGCCCTGCCTCATCATTGACAGCAACAGTACC
ATCCTGGTGGAGCCAGGCTGCCAGGCAGAGGTGACTGAGACTGGGGACATCCGCATCTCT
GTGGGGGCTGAGACAGCCAGCGTGGTGGGCACGCAGCTTGACCCCATCCACCTTACCATC
TTCTCCCACCGCTTCATGAGCATTGCTGAGCAGATGGGCCGCATCCTGCAGCGCACGGCC
ATCTCCACCAACATCAAGGAGCGTCTGGACTTCTCCTGCGCCCTCTTTGGGCCCGACGGG
GGGCTGGTCTCCAACGTCCCTCACATCCCTGTGCACCTGGGTGCCATGCAGGAGACGGTG
CAGTTCCAGATTCAGCAGTTGGGGGCTGATCTCCACCCCGGCGATGTGCTGCTGAGCAAC
CACCCCAGCGCGGGGGGCAGCCACTTGCCAGACCTGACTGTCATCACACCGGTGTTTTGG
CCGGGTCAGACACGGCCTGTGTTCTATGTGGCCAGCCGTGGGCACCATGCAGACATTGGG
GGCATCACACCAGGCTCCATGCCCCCCCACTCCACCAGCCTGCAGCAGGAGGGCGCGGTC
TTCCTTTCCTTCAAACTTGTGCATGGGGGAGTCTTCCAGGAAGAGGCGGTGACTGAAGCC
CTGCGGGCGCCAGGCAAGATCCCAGGCTGCAGCGGGACACGGAACCTGCACGACAACCTG
TCGGATCTGCGCGCCCAGGTGGCGGCCAACCAGAAGGGCATCCAGCTGGTGGGCGAGCTC
ATCGGGCAGTACGGCCTGGACGTGGTGCAGGCCTACATGGGCCACATTCAGGCAAACGCG
GAGCTCGCTGTGAGGGACATGCTCCGGGCCTTTGGAACTGCCCGGCAGGCCCGGGGCCTG
CCCCTGGAGGTGTCTGCAGAGGACCACATGGACGACGGTTCCCCTATCCGACTCCGAGTG
CAGATCAACATGAGTCAGGGTAGCGCGGTGTTTGATTTCAGCGGCTCAGGGCCAGAGGTG
TTCGGCAACCTCAACGCGCCGCGGGCCATCACGCTGTCTGCGCTCATCTACTGTCTTCGC
TGTCTGGTTGGCCGCGACATCCCACTCAACCAGGGCTGCCTGGCTCCGGTGCGCGTGGTG
ATTCCTAAAGGCTCCATCCTAGACCCTTCCCCCGACGCGGCCGTGGTGGGCGGCAACGTG
CTCACGTCGCAGCGCGTGGTGGACGTCATCCTGGGGGCCTTCGGGGCCTGCGCCGCTTCC
CAGGGCTGCATGAACAACGTGACCTTGGGCAACGCCCACATGGGCTACTACGAGACGGTG
GCGGGCGGTGCGGGCGCGGGACCGGGTTGGCACGGGCGCAGCGGCGTGCACAGCCACATG
ACCAACACGCGCATCACCGACCCCGAGATCCTGGAGAGCAGGTACCCGGTTATCCTGCGC
CGCTTCGAGCTAAGGCTGGGGTCCGGGGGTCGCGGCCGCTTCCGGGGCGGCGATGGCATT
ATCCGTGAGCTGCTTTTCCGCGAGGAGGCGCTGCTGTCCGTGCTGACTGAGCGCCGCGCC
TTCCAGCCGTATGGCCTGATGGGGGGTGAGCCTGGTGCCCGGGGCCTAAACCTACTCATC
CGGAAGGACGGCCGGACAGTAAACCTGGGTGGGAAGACCTCGGTGCCCGTGTACCCCGGG
GACGTGTTCTGTCTGCACACACCAGGCGGTGGGGGCTACGGGGACCCGGGAGACCCCGCC
CCACTGCCAGGTTCGCCCTTGCAGCCCCTAGCCTTCCCGGAGAGGGGCAGCGTGTATGAG
TACCGCAGGGCCCAGGAGGCTGTGTGA
Enzyme 23 GenBank Gene ID AB121737 Link Image
Enzyme 23 GeneCard ID OPLAH Link Image
Enzyme 23 GenAtlas ID Not Available
Enzyme 23 HGNC ID Not Available
Enzyme 23 Chromosome Location Chromosome:8
Enzyme 23 Locus 8q24.3
Enzyme 23 SNPs SNPJam Report Link Image
Enzyme 23 General References
  1. [PubMed Link Image]
Enzyme 23 Metabolite References Not Available
Enzyme 24 [top]
Enzyme 24 ID 858
Enzyme 24 Name Alanine aminotransferase 1
Enzyme 24 Synonyms
  1. ALT1
  2. Glutamic--pyruvic transaminase 1
  3. Glutamate pyruvate transaminase 1
  4. GPT 1
  5. Glutamic--alanine transaminase 1
Enzyme 24 Gene Name GPT
Enzyme 24 Protein Sequence >Alanine aminotransferase 1
MALRAGEHSQEAANGLKEKVLTLDSMNPYVRRVEYAVRGPIVQRALELEQELRQGVKKPF
TEVIRANIGDAQAMGQIPITFPRQVLALCVHPDLLNSPDFPDDAKRRAERILQACGGHSL
GAYSISAGVQMIREDVARYIERRDGGIPADPNNIFLSTGASDAIVTVLKLLVTGEGRTRT
GVLIPIPQYPLYSAALAEFNAVQVDYYLDEERAWALDVAELRRALRQARDHCRPRALCVI
NPGNPTGQVQTRECIEDVIRFAYEEKLFLLADEVYQDNVYAESSQFHSFKKVLTEMGPPY
AAQQELASFHSISKGYMGECGFRGGYVEVVNMDAAVKQQMQKLRSVRLCPPTPGQVLLDV
AVSPPAPSDPSFPRFQAERRAVLAELAAKAKLTEQVFNEAPGIRCNPVQGAMYSFPRVQL
PPRAVQRAQELGLAPDMFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPMEKLRPL
LEKLSQFHAKFTREYS
Enzyme 24 Number of Residues 496
Enzyme 24 Molecular Weight 55275.0
Enzyme 24 Theoretical pI 7.42
Enzyme 24 GO Classification
Function
Process
Component
Enzyme 24 General Function Amino acid transport and metabolism
Enzyme 24 Specific Function Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles
Enzyme 24 Pathways
  • Amino-acid degradation
  • L-alanine degradation via transaminase pathway
  • pyruvate from L-alanine:step 1/1
Enzyme 24 Reactions Not Available
Enzyme 24 Pfam Domain Function
Enzyme 24 Signals
  • None
Enzyme 24 Transmembrane Regions
  • None
Enzyme 24 Essentiality Not Available
Enzyme 24 GenBank ID Protein 134024764 Link Image
Enzyme 24 UniProtKB/Swiss-Prot ID A4IFH5 Link Image
Enzyme 24 UniProtKB/Swiss-Prot Entry Name ALAT1_BOVIN Link Image
Enzyme 24 PDB ID Not Available
Enzyme 24 Cellular Location Not Available
Enzyme 24 Gene Sequence >1491 bp
ATGGCCTTGAGGGCAGGTGAGCACAGCCAGGAGGCAGCAAATGGGCTGAAGGAGAAGGTG
CTGACACTGGACTCCATGAATCCTTATGTCCGGAGGGTGGAGTATGCGGTGCGAGGCCCC
ATCGTTCAGCGGGCACTGGAGCTGGAGCAGGAGCTGCGCCAGGGCGTAAAGAAGCCCTTC
ACCGAGGTCATCCGCGCCAACATCGGGGACGCACAGGCCATGGGGCAGATCCCTATCACC
TTCCCGCGCCAGGTCCTGGCCCTCTGCGTCCATCCCGATCTCCTGAACAGCCCCGACTTC
CCCGACGACGCCAAGAGGAGGGCGGAGCGCATCTTGCAGGCGTGTGGGGGCCACAGCCTG
GGGGCCTACAGCATCAGCGCTGGCGTCCAGATGATCCGTGAGGATGTGGCGCGGTACATC
GAGCGGCGCGATGGAGGCATTCCTGCCGACCCCAATAACATCTTTCTGTCCACGGGGGCC
AGCGATGCCATTGTGACGGTGCTGAAGTTGCTGGTAACCGGCGAGGGTCGCACGCGCACG
GGCGTGCTTATCCCTATCCCTCAGTATCCACTCTACTCCGCCGCGCTGGCCGAGTTCAAT
GCGGTGCAGGTGGACTACTACCTGGACGAGGAGCGTGCCTGGGCGCTCGATGTGGCCGAG
CTGCGGCGCGCGCTGCGCCAGGCGCGTGACCACTGCCGCCCCCGCGCGCTCTGCGTCATC
AACCCCGGGAACCCCACCGGGCAGGTGCAGACCCGCGAGTGCATCGAGGACGTGATCCGC
TTCGCCTATGAGGAGAAGCTTTTCCTATTGGCCGATGAGGTGTACCAAGACAACGTGTAT
GCCGAGAGCTCGCAGTTCCACTCGTTCAAGAAGGTGCTCACGGAGATGGGGCCGCCGTAC
GCGGCGCAACAGGAGCTCGCCTCCTTCCACTCGATCTCCAAGGGCTACATGGGCGAGTGC
GGCTTCCGCGGCGGCTACGTGGAGGTGGTGAATATGGACGCTGCGGTGAAGCAGCAGATG
CAGAAGCTGCGGAGCGTGCGGCTGTGCCCACCCACCCCGGGCCAGGTCCTGCTCGACGTG
GCTGTCAGCCCGCCGGCGCCCTCAGACCCCTCCTTCCCGCGGTTCCAGGCGGAGAGGAGG
GCGGTGCTGGCCGAGCTGGCTGCCAAGGCCAAGCTCACGGAGCAGGTCTTCAACGAAGCT
CCCGGCATCCGCTGCAATCCGGTGCAGGGCGCCATGTATTCGTTCCCGCGCGTGCAGCTG
CCCCCGCGTGCGGTGCAGCGCGCTCAGGAGCTGGGCCTGGCTCCCGACATGTTCTTCTGC
CTGCGCCTCCTAGAGGAGACTGGCATCTGCGTGGTGCCTGGGAGTGGCTTTGGACAACGG
GAAGGCACCTACCACTTTCGGATGACTATTCTGCCCCCCATGGAGAAGCTACGGCCCCTG
CTGGAGAAGCTGAGCCAGTTCCATGCGAAGTTCACCCGCGAGTACTCCTGA
Enzyme 24 GenBank Gene ID BC134583 Link Image
Enzyme 24 GeneCard ID GPT Link Image
Enzyme 24 GenAtlas ID Not Available
Enzyme 24 HGNC ID Not Available
Enzyme 24 Chromosome Location Chromosome:8
Enzyme 24 Locus 8q24.3
Enzyme 24 SNPs SNPJam Report Link Image
Enzyme 24 General References Not Available
Enzyme 24 Metabolite References Not Available
Enzyme 25 [top]
Enzyme 25 ID 859
Enzyme 25 Name Tyrosine aminotransferase
Enzyme 25 Synonyms
  1. TAT
  2. L-tyrosine:2-oxoglutarate aminotransferase
Enzyme 25 Gene Name TAT
Enzyme 25 Protein Sequence >Tyrosine aminotransferase
MQDHGSLPSVLDVHVNVAGRSSVLGKVKSRKARWSVRPSDMSNKTFNPIRAIVDNMKVKP
NPNKTMIALSIGDPTVFGNLPTDPEVTQAMKDALDSGKFNGYVPSIGYLSSREEVASYYH
CPEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILVPRPGFSLYRTLAESMGIEVKLYN
LLPEKNWEIDLKQLESLIDEKTVCLIVNNPSNPCGSVFSRRHLQKILAVAARQCVPILAD
EIYGDMVFSDSKFEPLATLSSKVPILSCGGLAKRWLVPGWRMGWILIHDRRDIFGNEIRD
GLTKLSQRILGPCTLVQGALKSILCRTPRVFYHNTLSFLKSNADLCYGALAAIPGLRPIH
PSGAMYLMVGIEMEHFPEFENDVEFTEQLVAEQSVHCLPATCFEYPNFFRVVITVPEVMM
LEACSRIQEFCEQHYHCAEGSQEECDK
Enzyme 25 Number of Residues 447
Enzyme 25 Molecular Weight 49691.0
Enzyme 25 Theoretical pI 6.43
Enzyme 25 GO Classification
Function
Process
Component
Enzyme 25 General Function Amino acid transport and metabolism
Enzyme 25 Specific Function L-tyrosine + 2-oxoglutarate = 4- hydroxyphenylpyruvate + L-glutamate
Enzyme 25 Pathways
  • Amino-acid degradation
  • L-phenylalanine degradation
  • acetoacetate and fumarate from L-phenylalanine:step 2/6
Enzyme 25 Reactions Not Available
Enzyme 25 Pfam Domain Function
Enzyme 25 Signals
  • None
Enzyme 25 Transmembrane Regions
  • None
Enzyme 25 Essentiality Not Available
Enzyme 25 GenBank ID Protein 61555008 Link Image
Enzyme 25 UniProtKB/Swiss-Prot ID Q58CZ9 Link Image
Enzyme 25 UniProtKB/Swiss-Prot Entry Name ATTY_BOVIN Link Image
Enzyme 25 PDB ID Not Available
Enzyme 25 Cellular Location Not Available
Enzyme 25 Gene Sequence >1344 bp
ATGCAGGATCACGGCAGCCTCCCCTCAGTTCTGGATGTGCATGTCAACGTTGCTGGGAGA
AGCTCTGTGCTGGGAAAAGTGAAAAGCAGGAAGGCCAGATGGTCCGTGAGGCCCTCGGAC
ATGTCCAACAAAACTTTCAATCCCATCCGGGCCATTGTGGACAACATGAAGGTGAAGCCA
AATCCAAACAAGACCATGATTGCTTTGTCGATTGGGGACCCTACTGTATTTGGAAACCTG
CCGACAGATCCTGAAGTTACCCAAGCAATGAAAGATGCCCTCGACTCAGGGAAGTTTAAT
GGCTATGTCCCCTCCATTGGCTACTTATCCAGTCGGGAGGAAGTTGCTTCTTATTACCAC
TGTCCCGAGGCACCCCTGGAAGCTAAGGATGTCATTCTGACAAGTGGCTGCAGTCAGGCT
ATTGAACTGTGTTTGGCTGTGTTGGCCAACCCAGGGCAAAACATCCTAGTTCCGAGACCT
GGCTTCTCTCTCTACAGGACTCTGGCTGAATCTATGGGAATTGAGGTCAAACTCTACAAT
TTATTGCCAGAGAAGAATTGGGAAATTGACCTGAAACAATTAGAATCTCTGATTGATGAA
AAGACAGTTTGTCTTATTGTCAACAATCCATCAAACCCTTGTGGGTCAGTGTTCAGTAGA
CGTCATCTCCAGAAAATTTTGGCAGTGGCTGCAAGGCAATGTGTTCCCATTTTAGCTGAT
GAGATCTATGGAGACATGGTGTTTTCAGATTCCAAATTTGAGCCTCTGGCCACCCTCAGC
AGCAAAGTCCCCATCCTGTCCTGTGGAGGGCTGGCCAAGCGCTGGCTGGTTCCTGGCTGG
AGGATGGGCTGGATCCTTATCCATGACCGAAGAGATATTTTTGGCAATGAGATCCGAGAT
GGGCTGACGAAGCTAAGTCAACGGATCCTGGGCCCCTGCACCCTTGTCCAGGGAGCTCTG
AAAAGCATCCTGTGTCGCACCCCTCGTGTGTTCTACCACAACACTCTAAGCTTCCTCAAG
TCCAATGCGGATCTCTGCTATGGGGCATTGGCTGCCATCCCCGGACTCCGGCCCATTCAC
CCTTCTGGGGCCATGTACCTCATGGTTGGAATTGAGATGGAACATTTCCCAGAATTTGAG
AATGATGTGGAGTTCACGGAGCAGTTAGTTGCTGAGCAATCTGTCCACTGCCTCCCAGCA
ACGTGCTTTGAGTATCCAAATTTCTTCCGAGTGGTAATCACAGTCCCTGAAGTGATGATG
CTGGAGGCCTGTAGCCGGATCCAGGAGTTCTGTGAACAGCACTACCATTGTGCTGAAGGG
AGCCAGGAGGAATGTGACAAATAG
Enzyme 25 GenBank Gene ID BT021798 Link Image
Enzyme 25 GeneCard ID TAT Link Image
Enzyme 25 GenAtlas ID Not Available
Enzyme 25 HGNC ID Not Available
Enzyme 25 Chromosome Location Chromosome:1
Enzyme 25 Locus 16q22.1
Enzyme 25 SNPs SNPJam Report Link Image
Enzyme 25 General References
  1. [PubMed Link Image]
Enzyme 25 Metabolite References Not Available
Enzyme 26 [top]
Enzyme 26 ID 860
Enzyme 26 Name Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
Enzyme 26 Synonyms
  1. P5C dehydrogenase
  2. Aldehyde dehydrogenase family 4 member A1
Enzyme 26 Gene Name ALDH4A1
Enzyme 26 Protein Sequence >Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
MLLRSAALCRALLARRGRAAGLCRRCVSSLQVANEPVLAFTQGSPERDALQKALKELKGR
TEAIPCVVGDEEVWTSDVRYQASPFNHGHKVAKFCYADKALLHRAIGAALAARKEWDLKP
VADRAQVFLKAADLLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAMEL
EGEQPLSVPPSTNSMLYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAML
ASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQ
NLDRFRTFPRLAGECGGKNFHFVHRSADVDSVVSGTLRSAFEYGGQKCSACSRLYAPRSL
WPQIKGRLLEELGGIKVGNPAEDFGTFFSAVIDAKSFGRIRKWLEHARSSPSLTILAGGH
CDDSVGYFVEPCIVETKDPQDPIMKEEIFGPVLAVYVYPDEEYKETLRLVDSTTSYGLTG
AVFAQDKDVLREATELLRHAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYVLR
WTSPQVIKETHGPLGDWRYPYMQ
Enzyme 26 Number of Residues 563
Enzyme 26 Molecular Weight 61494.7
Enzyme 26 Theoretical pI 8.20
Enzyme 26 GO Classification
Function
Process
Component
Enzyme 26 General Function Energy production and conversion
Enzyme 26 Specific Function Irreversible conversion of delta-1-pyrroline-5- carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes
Enzyme 26 Pathways
  • Amino-acid degradation
  • L-proline degradation into L- glutamate
  • L-glutamate from L-proline:step 2/2
Enzyme 26 Reactions Not Available
Enzyme 26 Pfam Domain Function
Enzyme 26 Signals
  • None
Enzyme 26 Transmembrane Regions
  • None
Enzyme 26 Essentiality Not Available
Enzyme 26 GenBank ID Protein 157278942 Link Image
Enzyme 26 UniProtKB/Swiss-Prot ID A7YWE4 Link Image
Enzyme 26 UniProtKB/Swiss-Prot Entry Name AL4A1_BOVIN Link Image
Enzyme 26 PDB ID Not Available
Enzyme 26 Cellular Location Not Available
Enzyme 26 Gene Sequence >1692 bp
ATGCTGCTGCGTTCGGCCGCGCTCTGCCGCGCCCTACTGGCCCGCCGGGGGAGGGCGGCC
GGGCTGTGTCGGAGGTGCGTCTCCTCCCTCCAGGTGGCCAACGAGCCCGTGCTGGCATTC
ACGCAGGGCAGTCCTGAGCGAGATGCGCTGCAGAAGGCCCTGAAGGAGCTGAAGGGCCGG
ACGGAGGCCATCCCATGCGTGGTGGGGGACGAGGAGGTCTGGACCTCGGATGTGCGGTAC
CAGGCGTCGCCCTTCAACCATGGACACAAGGTGGCCAAGTTTTGCTACGCAGACAAGGCC
CTGCTCCACAGAGCCATCGGGGCCGCCTTGGCTGCCAGGAAGGAGTGGGACCTGAAGCCT
GTGGCGGACCGGGCGCAGGTCTTCCTGAAGGCAGCTGACCTGCTGAGCGGGCCACGCAGG
GCCGAGGTCCTGGCCAAGACCATGGTGGGGCAGGGGAAGACAGTGATCCAGGCGGAGATC
GACGCTGCGGCTGAACTCATCGACTTCTTCCGCTTCAATGCCAAGTTCGCCATGGAGCTG
GAAGGCGAGCAGCCCCTCAGCGTGCCGCCCAGCACCAACAGCATGCTGTACCGGGGGCTG
GAGGGCTTCGTGGCGGCCATCTCCCCCTTCAACTTCACTGCGATCGGGGGCAACCTGGCA
GGGGCTCCGGCCTTGATGGGCAACGTGGTCCTGTGGAAGCCCAGCGACACTGCCATGCTG
GCCAGCTATGCCGTCTACCGCATCCTCAGGGAGGCCGGGCTGCCCCCCAACATCATCCAG
TTTGTGCCAGCCGACGGGCCCACCTTCGGGGACACTGTCACCAGCTCAGAGCACCTGTGT
GGCATCAACTTCACAGGCAGTGTGCCCACCTTCAAACACCTGTGGAAGCAGGTGGCCCAG
AACCTGGACCGGTTCCGAACCTTCCCCCGCCTGGCTGGAGAGTGCGGGGGCAAGAACTTC
CACTTTGTGCACCGCTCGGCCGACGTGGACAGCGTGGTGAGTGGGACCCTGCGCTCGGCC
TTTGAGTACGGCGGCCAGAAGTGCTCAGCGTGCTCCCGCCTCTACGCGCCCCGCTCGCTG
TGGCCGCAGATCAAAGGGCGGCTGCTGGAGGAGCTCGGTGGGATCAAAGTGGGCAATCCT
GCAGAGGATTTTGGGACCTTCTTCTCTGCCGTGATTGATGCCAAGTCCTTCGGTCGCATC
CGGAAGTGGCTGGAGCACGCCCGCTCCTCGCCCAGCCTCACCATCCTGGCCGGGGGCCAC
TGTGACGACTCTGTGGGCTACTTTGTGGAGCCGTGCATCGTCGAGACCAAGGACCCCCAG
GACCCCATCATGAAGGAGGAGATCTTCGGTCCCGTGCTGGCCGTGTACGTCTACCCGGAC
GAGGAATACAAGGAGACGCTGCGGCTGGTCGACAGCACCACCAGCTACGGCCTCACGGGG
GCAGTGTTCGCCCAGGATAAGGACGTTCTCCGGGAGGCCACAGAGCTGCTGAGGCACGCC
GCGGGCAACTTCTACATCAACGACAAGTCCACCGGCTCGGTGGTGGGCCAGCAGCCCTTT
GGGGGCGCTCGAGCCTCGGGAACCAATGACAAGCCAGGCGGCCCCCACTATGTCCTGCGG
TGGACGTCGCCCCAGGTCATCAAGGAGACGCACGGGCCTCTGGGGGACTGGCGCTACCCG
TACATGCAGTGA
Enzyme 26 GenBank Gene ID BC134524 Link Image
Enzyme 26 GeneCard ID ALDH4A1 Link Image
Enzyme 26 GenAtlas ID Not Available
Enzyme 26 HGNC ID Not Available
Enzyme 26 Chromosome Location Chromosome:1
Enzyme 26 Locus 1p36
Enzyme 26 SNPs SNPJam Report Link Image
Enzyme 26 General References Not Available
Enzyme 26 Metabolite References Not Available
Enzyme 27 [top]
Enzyme 27 ID 861
Enzyme 27 Name Kynurenine--oxoglutarate transaminase 3
Enzyme 27 Synonyms
  1. Kynurenine--oxoglutarate transaminase III
  2. Kynurenine aminotransferase III
  3. KATIII
  4. Cysteine-S-conjugate beta-lyase 2
Enzyme 27 Gene Name CCBL2
Enzyme 27 Protein Sequence >Kynurenine--oxoglutarate transaminase 3
MFLAWERLCTLSCRPKFLKTVWASKILGLSTSAKMSLRFKNAKRIEGLDSNIWIEFTKLA
ADPSVVNLGQGLPDISPPVYVKEELSKIAAIDNLNQYTRGFGHPSLVKALSCLYEKFYHN
KINPNEEILVTVGAYGSLFNAIQGLIDEGDEVIVIVPFFDCYESMVRMAGATPVFVPLRC
KPVDGKKCSSSDWTLDPQELASKFNSKTKAIILNTPHNPLGKVYTKEELQVIADLCIKYD
TLCISDEVYEWLVYTGNKHFKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPKHLIK
HLQTVQQNTVYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVHLLESV
GLKSIVPDGGYFIIADVSLLDVDLLDMKDSNEPYDYKFVKWMIKNKKLSAIPVSAFCNAE
TKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSRQNS
Enzyme 27 Number of Residues 455
Enzyme 27 Molecular Weight 51471.2
Enzyme 27 Theoretical pI 7.82
Enzyme 27 GO Classification
Function
Process
Component
Enzyme 27 General Function Amino acid transport and metabolism
Enzyme 27 Specific Function Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond
Enzyme 27 Pathways Not Available
Enzyme 27 Reactions Not Available
Enzyme 27 Pfam Domain Function
Enzyme 27 Signals
  • None
Enzyme 27 Transmembrane Regions
  • None
Enzyme 27 Essentiality Not Available
Enzyme 27 GenBank ID Protein 112362049 Link Image
Enzyme 27 UniProtKB/Swiss-Prot ID Q0P5G4 Link Image
Enzyme 27 UniProtKB/Swiss-Prot Entry Name KAT3_BOVIN Link Image
Enzyme 27 PDB ID Not Available
Enzyme 27 Cellular Location Not Available
Enzyme 27 Gene Sequence >1368 bp
ATGTTTTTGGCCTGGGAGAGACTCTGCACCCTTAGCTGTAGACCTAAATTCCTGAAGACA
GTTTGGGCTTCAAAAATCCTTGGACTCTCTACTTCTGCTAAAATGTCTTTGAGATTCAAA
AATGCAAAACGAATTGAAGGCCTTGATAGCAATATATGGATTGAATTTACCAAACTGGCT
GCAGACCCTTCTGTTGTGAATCTTGGCCAAGGCCTTCCAGATATATCCCCTCCTGTATAT
GTAAAGGAAGAATTATCCAAGATTGCAGCAATTGATAATCTGAATCAGTACACACGGGGC
TTTGGTCATCCATCACTTGTGAAAGCTCTGTCCTGCCTATATGAAAAGTTTTATCACAAT
AAAATCAATCCAAATGAAGAAATCCTTGTGACAGTAGGAGCATATGGATCTCTTTTTAAT
GCCATTCAAGGATTGATTGATGAGGGGGATGAAGTCATAGTGATAGTGCCTTTCTTTGAC
TGCTATGAGTCCATGGTGAGAATGGCTGGAGCAACACCTGTTTTTGTTCCCCTGAGATGT
AAACCTGTTGATGGGAAAAAATGCTCTAGTTCTGACTGGACCTTAGATCCTCAAGAACTG
GCAAGCAAATTTAATTCCAAAACCAAAGCTATAATACTAAATACTCCACATAACCCCCTT
GGCAAGGTGTATACCAAAGAGGAACTCCAAGTAATTGCCGACCTTTGCATCAAATATGAC
ACACTCTGCATCAGTGATGAGGTTTATGAATGGCTTGTATATACTGGAAATAAGCATTTT
AAAATAGCCACTTTTCCAGGTATGTGGGAGAGAACAATAACCATAGGAAGTGCTGGAAAG
ACTTTCAGTGTAACTGGCTGGAAGCTTGGCTGGTCCATTGGTCCTAAACATTTGATAAAA
CATTTACAGACAGTTCAGCAAAACACCGTTTATACTTGTGCAACCCCTTTACAGGAAGCC
TTGGCTCAAGCTTTCTGGATTGACATCAAGCGCATGGATGACCCAGAATGTTACTTCAAT
TCTTTGCCAAAAGAGTTAGAAGTAAAAAGAGATCGGATGGTACATTTACTTGAAAGTGTT
GGCCTAAAATCCATAGTTCCTGATGGGGGATACTTCATCATTGCTGACGTGTCTTTGCTA
GATGTAGACCTCTTGGATATGAAGGACAGCAATGAACCTTATGACTATAAATTCGTGAAA
TGGATGATTAAAAATAAGAAACTGTCAGCCATCCCAGTTTCAGCATTCTGTAATGCAGAA
ACCAAATCACAGTTTGAGAAATTTGTGCGATTTTGCTTCATTAAAAAAGACAGTACACTG
GATGCCGCTGAAGAAATCATCAAGGCATGGAGTAGACAGAACTCTTGA
Enzyme 27 GenBank Gene ID BC120067 Link Image
Enzyme 27 GeneCard ID CCBL2 Link Image
Enzyme 27 GenAtlas ID Not Available
Enzyme 27 HGNC ID Not Available
Enzyme 27 Chromosome Location Chromosome:1
Enzyme 27 Locus 1p22.2
Enzyme 27 SNPs SNPJam Report Link Image
Enzyme 27 General References Not Available
Enzyme 27 Metabolite References Not Available
Enzyme 28 [top]
Enzyme 28 ID 862
Enzyme 28 Name Glutamate decarboxylase 1
Enzyme 28 Synonyms Not Available
Enzyme 28 Gene Name GAD1
Enzyme 28 Protein Sequence >Glutamate decarboxylase 1
MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
SRLVSAFKERQSSKNLLSCENSDKDGRFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWS
SKDGDGIFSPGGAISNMYSIMAARFKYFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAA
LGFGTDNVILIKCNERGKIIPADLETKILEAKQKGYVPLYVNATAGTTVYGAFDPIQEIA
DICEKYNLWLHVDAAWGGGLLMSQKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKE
KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQI
NKCLELAEYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGVPDSPERREKLHRVAP
KIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
Enzyme 28 Number of Residues 594
Enzyme 28 Molecular Weight 66783.9
Enzyme 28 Theoretical pI 7.18
Enzyme 28 GO Classification
Function
Process
Component
Enzyme 28 General Function Amino acid transport and metabolism
Enzyme 28 Specific Function Catalyzes the production of GABA
Enzyme 28 Pathways Not Available
Enzyme 28 Reactions Not Available
Enzyme 28 Pfam Domain Function
Enzyme 28 Signals
  • None
Enzyme 28 Transmembrane Regions
  • None
Enzyme 28 Essentiality Not Available
Enzyme 28 GenBank ID Protein 111305189 Link Image
Enzyme 28 UniProtKB/Swiss-Prot ID Q0VCA1 Link Image
Enzyme 28 UniProtKB/Swiss-Prot Entry Name DCE1_BOVIN Link Image
Enzyme 28 PDB ID Not Available
Enzyme 28 Cellular Location Not Available
Enzyme 28 Gene Sequence >1785 bp
ATGGCGTCTTCGACCCCTTCTTCGTCCGCAACCTCCTCGAACGCGGGAGCGGACCCCAAT
ACTACCAACCTGCGCCCCACAACGTATGACACCTGGTGCGGCGTGGCCCATGGATGCACC
AGAAAACTGGGGCTGAAGATCTGCGGCTTCTTGCAGAGGACCAACAGCCTGGAAGAGAAG
AGCAGGCTTGTGAGCGCCTTCAAGGAGAGGCAGTCCTCCAAGAACCTGCTTTCCTGTGAA
AACAGTGACAAGGATGGCCGCTTCCGCCGCACAGAGACAGACTTCTCCAACCTGTTCGCC
CGAGATCTGCTTCCGGCTAAGAACGGGGAGGAGCAAACTGTGCAATTCCTGTTGGAGGTG
GTAGACATACTCCTCAACTATGTCCGGAAGACGTTCGATCGCTCCACCAAAGTGCTGGAC
TTCCACCACCCCCACCAGCTGCTGGAAGGCATGGAGGGCTTCAACTTGGAACTCTCTGAC
CACCCCGAGTCCCTGGAGCAGATCCTGGTTGACTGCAGAGACACCCTGAAATATGGGGTC
CGCACAGGTCATCCACGATTTTTCAACCAGCTCTCCACAGGATTGGATATCATTGGTTTA
GCTGGCGAGTGGCTGACATCAACTGCCAATACCAATATGTTTACATATGAAATTGCACCA
GTGTTTGTCCTCATGGAGCAAATAACACTTAAGAAGATGAGAGAGATAGTTGGATGGTCA
AGTAAAGATGGTGATGGGATATTTTCTCCTGGGGGAGCCATATCCAACATGTACAGCATC
ATGGCTGCTCGCTTCAAGTACTTCCCGGAAGTTAAGACCAAGGGTATGGCGGCTGTGCCC
AAGCTTGTCCTCTTCACCTCAGAACACAGTCACTATTCCATAAAGAAAGCTGGGGCTGCA
CTTGGCTTTGGAACCGACAACGTGATTTTGATAAAGTGCAATGAAAGGGGGAAGATAATT
CCAGCTGATTTAGAGACAAAAATTCTTGAAGCCAAGCAAAAGGGTTACGTCCCTCTCTAC
GTCAATGCAACTGCTGGCACCACTGTTTATGGCGCTTTTGATCCGATACAGGAGATTGCA
GATATATGTGAGAAATACAACCTTTGGCTGCATGTCGATGCTGCCTGGGGTGGCGGGCTG
CTCATGTCCCAGAAGCACCGCCATAAGCTCAGTGGCATCGAGAGGGCCAACTCTGTCACC
TGGAACCCTCACAAGATGATGGGTGTGCTGCTGCAGTGCTCTGCCATTCTTGTAAAAGAA
AAGGGTATCCTCCAAGGATGCAACCAGATGTGTGCGGGATACCTCTTCCAGCCGGACAAG
CAGTATGATGTCTCCTATGACACTGGGGACAAGGCCATTCAGTGTGGCCGCCACGTAGAC
ATCTTCAAGTTCTGGCTGATGTGGAAAGCAAAGGGTACAGTGGGCTTTGAAAATCAGATC
AACAAATGCTTGGAACTGGCTGAATACCTCTATGCCAAGATTAAAAACAGAGAAGAATTT
GAGATGGTTTTTGATGGTGAGCCTGAGCATACGAACGTCTGTTTCTGGTATATTCCACAA
AGCCTCAGGGGTGTTCCAGATAGCCCCGAACGACGGGAAAAGCTACACAGGGTGGCCCCA
AAGATCAAAGCCCTGATGATGGAATCTGGCACAACCATGGTTGGCTACCAGCCTCAGGGG
GACAAGGCCAACTTCTTCCGGATGGTCATCTCCAACCCAGCCGCTACCCAATCTGATATT
GACTTCCTCATTGAGGAGATAGAGAGGCTGGGCCAGGATCTGTAA
Enzyme 28 GenBank Gene ID BC120278 Link Image
Enzyme 28 GeneCard ID GAD1 Link Image
Enzyme 28 GenAtlas ID Not Available
Enzyme 28 HGNC ID Not Available
Enzyme 28 Chromosome Location Chromosome:2
Enzyme 28 Locus 2q31
Enzyme 28 SNPs SNPJam Report Link Image
Enzyme 28 General References Not Available
Enzyme 28 Metabolite References Not Available
Enzyme 29 [top]
Enzyme 29 ID 2099
Enzyme 29 Name PRA1 family protein 3
Enzyme 29 Synonyms
  1. ADP-ribosylation factor-like protein 6-interacting protein 5
  2. ARL-6-interacting protein 5
  3. Aip-5
Enzyme 29 Gene Name ARL6IP5
Enzyme 29 Protein Sequence >PRA1 family protein 3
MDVNIAPLRAWDDFFPGSDRFARPDFRDISKWNNRVVSNLLYYQTNYLVVAAMMISVVGF
LSPFNMILGGIVVVLVFTGFVWAAHNKDILRRMKKQYPTAFVMVVMLASYFLISLFGGVM
VFVFGITFPLLLMFIHASLRLRNLKNKLENKMEEIGLKRTPMGIVLDALEQQEETITKFS
DYISKMKE
Enzyme 29 Number of Residues 188
Enzyme 29 Molecular Weight 21665.6
Enzyme 29 Theoretical pI 9.98
Enzyme 29 GO Classification
Function
Process
Component
Enzyme 29 General Function Involved in protein binding
Enzyme 29 Specific Function Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic
Enzyme 29 Pathways Not Available
Enzyme 29 Reactions Not Available
Enzyme 29 Pfam Domain Function
Enzyme 29 Signals
  • None
Enzyme 29 Transmembrane Regions
  • 36-56 57-77 94-114 115-135
Enzyme 29 Essentiality Not Available
Enzyme 29 GenBank ID Protein 59858163 Link Image
Enzyme 29 UniProtKB/Swiss-Prot ID Q5E9M1 Link Image
Enzyme 29 UniProtKB/Swiss-Prot Entry Name PRAF3_BOVIN Link Image
Enzyme 29 PDB ID Not Available
Enzyme 29 Cellular Location Not Available
Enzyme 29 Gene Sequence >567 bp
ATGGACGTGAATATCGCTCCTCTCCGCGCCTGGGACGATTTCTTCCCAGGCTCTGACCGC
TTTGCCCGGCCGGACTTCAGGGACATTTCCAAATGGAACAACCGTGTGGTGAGCAACCTG
CTCTATTACCAGACCAACTACCTAGTGGTGGCTGCCATGATGATTTCCGTTGTGGGGTTC
CTGAGCCCCTTCAACATGATCCTTGGAGGCATTGTGGTGGTGCTGGTGTTCACAGGCTTC
GTGTGGGCAGCCCACAATAAAGACATCCTCCGTCGGATGAAGAAGCAGTACCCCACAGCG
TTTGTCATGGTGGTCATGCTAGCCAGCTACTTCCTCATCTCCCTCTTCGGGGGAGTCATG
GTCTTTGTGTTTGGTATCACATTTCCTTTGCTGTTGATGTTCATCCATGCGTCGCTGAGG
CTCCGGAACCTCAAGAACAAACTGGAGAATAAAATGGAGGAAATTGGTCTGAAGAGGACA
CCCATGGGGATTGTCCTAGATGCCCTGGAGCAGCAGGAGGAAACCATCACCAAGTTTTCT
GACTATATCAGTAAAATGAAGGAGTAA
Enzyme 29 GenBank Gene ID BT020899 Link Image
Enzyme 29 GeneCard ID ARL6IP5 Link Image
Enzyme 29 GenAtlas ID Not Available
Enzyme 29 HGNC ID Not Available
Enzyme 29 Chromosome Location Chromosome:3
Enzyme 29 Locus 3p14
Enzyme 29 SNPs SNPJam Report Link Image
Enzyme 29 General References
  1. [PubMed Link Image]
Enzyme 29 Metabolite References Not Available
Enzyme 30 [top]
Enzyme 30 ID 2100
Enzyme 30 Name SLC1A6 protein
Enzyme 30 Synonyms Not Available
Enzyme 30 Gene Name SLC1A6
Enzyme 30 Protein Sequence >SLC1A6 protein
MSSHGNSLFLRESGQRLGRVGWLQRLQESLQQRALRMRLRLQTMTREHVLRFLRRNAFIL
LTVSAVVIGVSLAFALRPYQLSYRQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASLD
NKATGRMGMRAAVYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETIPTADAFMD
LVRNMFPPNLVEACFKQFKTQYSTRLVTRTVVRTDNGSELGTSMPPLSSLENGTGLLENV
TRALGTLQEVLSFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLN
EAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFVHAGGILPL
IYFLITHRNPFPFIGGILQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGA
TVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVL
TSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELELQEAELTLPSLG
KPYKSLMAQEKGASRGRGGNESAM
Enzyme 30 Number of Residues 564
Enzyme 30 Molecular Weight 61423.7
Enzyme 30 Theoretical pI 9.68
Enzyme 30 GO Classification
Function
Process
Component
Enzyme 30 General Function Energy production and conversion
Enzyme 30 Specific Function Not Available
Enzyme 30 Pathways Not Available
Enzyme 30 Reactions Not Available
Enzyme 30 Pfam Domain Function
Enzyme 30 Signals
  • None
Enzyme 30 Transmembrane Regions
  • None
Enzyme 30 Essentiality Not Available
Enzyme 30 GenBank ID Protein 148878071 Link Image
Enzyme 30 UniProtKB/Swiss-Prot ID A6H774 Link Image
Enzyme 30 UniProtKB/Swiss-Prot Entry Name A6H774_BOVIN Link Image
Enzyme 30 PDB ID Not Available
Enzyme 30 Cellular Location Not Available
Enzyme 30 Gene Sequence >1695 bp
ATGAGCAGCCATGGCAACAGCCTCTTTCTGCGGGAGAGTGGCCAGCGGCTGGGCCGGGTG
GGCTGGCTACAGCGGCTGCAGGAGAGCCTGCAGCAGAGAGCACTGCGCATGCGCCTGCGC
CTGCAGACCATGACACGTGAGCACGTGCTGCGGTTCCTGCGCAGGAATGCCTTCATCCTG
CTGACTGTCAGTGCCGTGGTCATTGGGGTCAGCCTGGCCTTTGCCCTGCGCCCATACCAG
CTCAGCTACCGCCAGATCAAGTACTTCTCTTTCCCTGGAGAGCTCCTCATGAGGATGCTG
CAGATGCTGGTGCTGCCTCTCATTGTCTCCAGCCTGGTCACAGGTATGGCGTCCCTGGAT
AACAAGGCGACGGGGCGGATGGGGATGCGGGCAGCTGTGTACTACATGGTGACCACGGTC
ATCGCGGTCTTCATCGGCATCCTCATGGTCACCATCATCCACCCTGGGAAAGGCTCCAAG
GAGGGGCTGCACCGAGAGGGTCGGATCGAGACCATCCCCACGGCAGATGCCTTCATGGAC
CTGGTCAGAAATATGTTTCCACCCAACCTTGTGGAGGCCTGCTTCAAACAGTTTAAGACA
CAGTACAGCACGAGGTTGGTAACCAGGACCGTCGTGAGGACAGATAATGGATCTGAGCTG
GGCACCTCTATGCCGCCTTTATCCTCACTGGAGAATGGAACCGGCCTCCTGGAAAACGTC
ACGCGAGCCTTGGGCACCCTGCAGGAGGTGCTGAGCTTTGAAGAGACCGTCCCTGTGCCT
GGCTCGGCCAATGGTATCAATGCCCTGGGCCTTGTGGTCTTCTCAGTGGCCTTCGGGCTG
GTCATTGGTGGCATGAAACACAAGGGCCGAGTCCTGCGGGACTTCTTCGACAGCCTCAAT
GAGGCTATTATGAGGCTGGTGGGCATCATTATCTGGTATGCACCCGTGGGTATCCTGTTC
CTGATTGCTGGCAAGATCTTAGAGATGGAAGACATGGCTGTCCTGGGGGGTCAGCTGGGC
ATGTACACCCTGACCGTCATCGTGGGTTTGTTCGTTCATGCCGGTGGCATCCTGCCTCTC
ATCTATTTCCTCATCACCCACCGGAATCCTTTCCCCTTCATTGGAGGAATACTGCAGGCT
CTCATCACAGCCATGGGCACGTCTTCCAGCTCTGCGACACTACCCATCACCTTCCGCTGT
CTGGAGGAGGGCCTTGGTGTGGACCGCCGCATCACCAGGTTCGTACTGCCCGTGGGGGCC
ACTGTCAACATGGACGGCACCGCCCTCTATGAGGCCCTGGCCGCCATCTTTATCGCCCAA
GTCAACAACTACGAGCTCAACCTGGGCCAGATCACAACTATCAGTATCACAGCTACAGCA
GCCAGCGTCGGGGCTGCCGGCATCCCCCAGGCAGGTCTGGTCACCATGGTGATTGTGCTC
ACCTCGGTCGGCTTGCCCACTGAAGACATCACGCTCATCATCGCTGTGGACTGGTTCCTT
GACCGACTTCGCACAATGACCAATGTGCTGGGGGACTCTATCGGAGCGGCCGTCATTGAA
CATCTGTCTCAGCGGGAGCTGGAGCTGCAAGAAGCTGAACTCACCCTCCCCAGCCTGGGG
AAGCCCTACAAGTCACTCATGGCACAGGAGAAAGGGGCGTCCAGGGGACGGGGAGGAAAC
GAGAGTGCTATGTGA
Enzyme 30 GenBank Gene ID BC146139 Link Image
Enzyme 30 GeneCard ID SLC1A6 Link Image
Enzyme 30 GenAtlas ID Not Available
Enzyme 30 HGNC ID Not Available
Enzyme 30 Chromosome Location Chromosome:1
Enzyme 30 Locus 19p13.12
Enzyme 30 SNPs SNPJam Report Link Image
Enzyme 30 General References Not Available
Enzyme 30 Metabolite References Not Available
Enzyme 31 [top]
Enzyme 31 ID 2101
Enzyme 31 Name Solute carrier family 1 member 2
Enzyme 31 Synonyms Not Available
Enzyme 31 Gene Name SLC1A2
Enzyme 31 Protein Sequence >Solute carrier family 1 member 2
PTEDISLLVAVDWLLARMRTSVNVV
Enzyme 31 Number of Residues 25
Enzyme 31 Molecular Weight 2798.3
Enzyme 31 Theoretical pI 4.37
Enzyme 31 GO Classification
Function
Process
Component
Enzyme 31 General Function Involved in glutamate:sodium symporter activity
Enzyme 31 Specific Function Not Available
Enzyme 31 Pathways Not Available
Enzyme 31 Reactions Not Available
Enzyme 31 Pfam Domain Function
Enzyme 31 Signals
  • None
Enzyme 31 Transmembrane Regions
  • None
Enzyme 31 Essentiality Not Available
Enzyme 31 GenBank ID Protein 146336965 Link Image
Enzyme 31 UniProtKB/Swiss-Prot ID A5HSH1 Link Image
Enzyme 31 UniProtKB/Swiss-Prot Entry Name A5HSH1_BOVIN Link Image
Enzyme 31 PDB ID Not Available
Enzyme 31 Cellular Location Not Available
Enzyme 31 Gene Sequence Not Available
Enzyme 31 GenBank Gene ID EF551337 Link Image
Enzyme 31 GeneCard ID SLC1A2 Link Image
Enzyme 31 GenAtlas ID Not Available
Enzyme 31 HGNC ID Not Available
Enzyme 31 Chromosome Location Chromosome:1
Enzyme 31 Locus 11p13-p12
Enzyme 31 SNPs SNPJam Report Link Image
Enzyme 31 General References Not Available
Enzyme 31 Metabolite References Not Available