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Bovine Metabolome Database



Showing metabocard for Guanine (BMDB00132)

Legend: metabolite field enzyme field

Version 1.0
Creation Date 2005-11-16 15:48:42
Update Date 2009-05-05 20:57:42
Accession Number BMDB00132
Common Name Guanine
Description Guanine is one of the five main nucleobases found in the nucleic acids DNA and RNA. Guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Being unsaturated, the bicyclic molecule is planar. The guanine nucleoside is called guanosine. The first isolation of guanine was reported in 1844 from the excreta of sea birds, known as guano, which was used as a source of fertilizer. High affinity binding of guanine nucleotides and the ability to hydrolyze bound GTP to GDP are characteristics of an extended family of intracellular proteins. Guanine nucleotide-binding regulatory proteins may be involved in the activation of phospholipases C and A2 by hormones and other ligands. The binding of hormones to receptors that activate phospholipase C is decreased by guanine nucleotides and these hormones also stimulate a high-affinity GTPase activity in cell membranes. Effects of hormones on phospholipase C activity in cell-free preparations are dependent on the presence of guanine nucleotides. Hypoxanthine-guanine phosphoribosyltransferase (HPRT, EC 2.4.2.8) is a purine salvage enzyme that catalyses the conversion of hypoxanthine and guanine to their respective mononucleotides. Partial deficiency of this enzyme can result in the overproduction of uric acid leading to a severe form of gout, whilst a virtual absence of HPRT activity causes the Lesch-Nyhan syndrome which is characterised by hyperuricaemia, mental retardation, choreoathetosis and compulsive self-mutilation. Peroxynitrite induces DNA base damage predominantly at guanine (G) and 8-oxoguanine (8-oxoG) nucleobases via oxidation reactions. G and 8-oxoG are the most reactive bases toward Peroxynitrite and possibly the major contributors to peroxynitrite-derived genotoxic and mutagenic lesions. The neutral G radical, reacts with NO2 to yield 8-nitroguanine and 5-nitro-4-guanidinohydantoin. (PMID: 16352449, 2435586, 2838362, 1487231)
Synonyms
  1. GUN
  2. Guanine enol
  3. Guanine
  4. Guanin
  5. GUA
  6. Dew Pearl
  7. CI Natural white 1
  8. C.I. Natural White 1
  9. 6-Hydroxy-2-aminopurine
  10. 2-Aminohypoxanthine
  11. 2-amino-Hypoxanthine
  12. 2-Amino-6-purinol
  13. 2-Amino-6-hydroxypurine
  14. 2-Amino-6-hydroxy-1H-purine
  15. 2-amino-3,7-dihydro-6H-purin-6-one
  16. 2-Amino-1,9-dihydro-purin-6-one
  17. 2-amino-1,9-dihydro-6H-purin-6-one
  18. 2-amino-1,7-dihydro-6H-Purin-6-one
  19. Stella Polaris
  20. Pearl Essence
  21. Pathocidin
  22. Naturon
  23. Natural White 1
  24. Natural pearl essence
  25. Mearlmaid AA
  26. Mearlmaid
Chemical IUPAC Name 2-amino-3,7-dihydropurin-6-one
Chemical Formula C5H5N5O
Chemical Structure Structure
Chemical Taxonomy
Kingdom
  • Organic
Super Class
  • Nucleosides and Nucleoside conjugates
Class
  • Purines and Purine Derivatives
Sub Class
  • Hydroxy purines
Family
  • Mammalian_Metabolite
Species
  • primary amine; primary aromatic amine; oxo(het)arene; aromatic compound; heterocyclic compound
Biofunction
Application
Source
  • Endogenous
Average Molecular Weight 151.126
Monoisotopic Molecular Weight 151.049408
Isomeric SMILES NC1=NC(=O)C2=C(N1)N=CN2
Canonical SMILES NC1=NC(=O)C2=C(N1)N=CN2
KEGG Compound ID C00242 Link Image
BioCyc ID GUANINE Link Image
BiGG ID 34363 Link Image
Wikipedia Link Guanine Link Image
METLIN ID 315 Link Image
PubChem Compound 764 Link Image
PubChem Substance 3133367 Link Image
ChEBI ID 16235 Link Image
CAS Registry Number 73-40-5
InChI Identifier InChI=1/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
Synthesis Reference Xiao, Xuhua; Ma, Weiyong. One-pot synthesis of guanine. Faming Zhuanli Shenqing Gongkai Shuomingshu (2007), 10pp.
Melting Point (Experimental) 360 oC
Experimental Water Solubility 2.08 mg/mL at 37 oC [YALKOWSKY,SH & DANNENFELSER,RM (1992)] Source: PhysProp
Predicted Water Solubility 2.31 mg/mL [Predicted by ALOGPS] Calculated using ALOGPS
Physiological Charge 0
State Solid
Experimental LogP/Hydrophobicity -0.91 [HANSCH,C ET AL. (1995)] Source: PhysProp
Predicted LogP/Hydrophobicity -0.9 [Predicted by PubChem via XLOGP]; -0.92 [Predicted by ALOGPS] Calculated using ALOGPS
Material Safety Data Sheet (MSDS)
MOL File Show
SDF File Show
PDB File Show
2D Structure
3D Structure
Experimental PDB ID 1A95 Link Image
Experimental PDB File Show
Experimental PDB Structure
Experimental 1H NMR Spectrum Download Spectrum
Download FID (Bruker)
Show Experimental Conditions Link Image
Experimental 13C NMR Spectrum Not Available
Experimental 13C HSQC Spectrum Download Spectrum
Download FID (Bruker)
Show Experimental Conditions Link Image
Predicted 1H NMR Spectrum Show Image
Show Peaklist
Predicted 13C NMR Spectrum Show Image
Show Peaklist
Mass Spectrum Not Available
Simplified TOCSY Spectrum Not Available
BMRB Spectrum Show Image
Show Peaklist
Cellular Location
  • Cytoplasm (Predicted from LogP)
  • Extracellular
Biofluid Location
  • Breast_Milk
Tissue Location
Tissue References
Epidermis
Fibroblasts
Intestine
Muscle
Myelin
Neuron
Prostate
Spleen
Testes
Concentrations (Normal)
Biofluid Breast_Milk
Value 6.500 uM
Age N/A
Sex N/A
Condition Normal
Comments Raw. whole.
References
Concentrations (Abnormal) Not Available
Pathway Names
  • Purine Metabolism
HMDB Pathways
Name Purine Metabolism
Image Show Link Image
KEGG Pathways
Name Purine Metabolism
Image Show Link Image
SimCell Pathways
Name Purine Metabolism
Image Show Link Image
Graph Show Link Image
SBML Download (XML) Link Image
General References
  1. Wikipedia Link Image
Metabolic Enzymes
  1. Hypoxanthine-guanine phosphoribosyltransferase
  2. Guanine nucleotide-binding protein G(t) subunit alpha-1
  3. Guanine nucleotide-binding protein G(t) subunit alpha-3
  4. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
  5. Guanine nucleotide-binding protein G(t) subunit alpha-2
  6. Guanine nucleotide binding protein-like 2 (Nucleolar)
  7. Guanine nucleotide-binding protein subunit alpha-11
  8. Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
  9. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
  10. Guanine nucleotide-binding protein subunit alpha-14
  11. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  12. Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  13. Guanine nucleotide-binding protein G(i), alpha-1 subunit
  14. Guanine nucleotide binding protein alpha subunit
  15. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
  16. Guanine nucleotide-binding protein, beta-1 subunit
  17. Guanine nucleotide-binding protein-like 3-like protein
  18. Guanine nucleotide-binding protein G(T) subunit gamma-T1
  19. Guanine nucleotide-binding protein G(o) subunit alpha
  20. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
  21. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
  22. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
  23. Target of rapamycin complex subunit LST8
  24. Guanine nucleotide-binding protein Gq
  25. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  26. Guanine nucleotide binding protein-like 2 (Nucleolar)
  27. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Enzyme 1 [top]
Enzyme 1 ID 440
Enzyme 1 Name Hypoxanthine-guanine phosphoribosyltransferase
Enzyme 1 Synonyms
  1. HGPRTase
  2. HGPRT
Enzyme 1 Gene Name HPRT1
Enzyme 1 Protein Sequence >Hypoxanthine-guanine phosphoribosyltransferase
MAARSPSVVISDDEPGYDLNLFCIPNHYAEDLEKVFIPHGLIMDRTERLARDVMKEMGGH
HIVALCVLKGGYKFFADLLDYIKALNRNSDKSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
DLSTLTGKNVLIVEDIIDTGKTMQTLLALVKKHKPKMVKVASLLMKRTPRSVGYKPDFVG
FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
Enzyme 1 Number of Residues 218
Enzyme 1 Molecular Weight 24498.3
Enzyme 1 Theoretical pI 7.97
Enzyme 1 GO Classification
Function
Process
Component
Enzyme 1 General Function Nucleotide transport and metabolism
Enzyme 1 Specific Function IMP + diphosphate = hypoxanthine + 5-phospho- alpha-D-ribose 1-diphosphate
Enzyme 1 Pathways
  • Purine metabolism
  • IMP biosynthesis via salvage pathway
  • IMP from hypoxanthine:step 1/1
Enzyme 1 Reactions Not Available
Enzyme 1 Pfam Domain Function
Enzyme 1 Signals
  • None
Enzyme 1 Transmembrane Regions
  • None
Enzyme 1 Essentiality Not Available
Enzyme 1 GenBank ID Protein 74268428 Link Image
Enzyme 1 UniProtKB/Swiss-Prot ID Q3SZ18 Link Image
Enzyme 1 UniProtKB/Swiss-Prot Entry Name HPRT_BOVIN Link Image
Enzyme 1 PDB ID 1BZY Link Image
Enzyme 1 PDB File Show
Enzyme 1 3D Structure
Enzyme 1 Cellular Location Not Available
Enzyme 1 Gene Sequence >657 bp
ATGGCGGCCCGCAGCCCCAGCGTGGTGATTAGCGATGATGAACCAGGTTATGACCTAAAT
TTATTTTGTATACCCAATCATTATGCTGAGGATTTGGAGAAGGTGTTTATTCCTCATGGA
CTAATTATGGACAGGACCGAACGGCTGGCTCGAGATGTGATGAAGGAGATGGGTGGCCAT
CACATTGTGGCCCTCTGTGTGCTCAAGGGGGGCTATAAGTTCTTTGCCGACCTGTTGGAT
TACATCAAAGCACTGAACAGAAATAGTGACAAATCCATTCCTATGACTGTGGATTTTATC
AGACTGAAGAGCTACTGTAACGACCAGTCAACAGGCGACATAAAAGTAATTGGTGGAGAT
GATCTCTCAACTTTAACTGGAAAGAATGTCTTGATTGTCGAAGATATAATTGACACTGGG
AAGACAATGCAGACTTTGCTTGCCTTGGTCAAGAAGCATAAACCAAAGATGGTCAAGGTT
GCGAGCTTGCTGATGAAAAGGACCCCTCGAAGTGTTGGATATAAACCAGACTTTGTTGGA
TTTGAAATTCCAGACAAGTTTGTTGTGGGATATGCCCTTGACTATAATGAATACTTCAGG
GACTTGAATCACGTGTGTGTCATTAGCGAAACTGGAAAAGCAAAATACAAAGCCTAA
Enzyme 1 GenBank Gene ID BC103248 Link Image
Enzyme 1 GeneCard ID HPRT1 Link Image
Enzyme 1 GenAtlas ID Not Available
Enzyme 1 HGNC ID Not Available
Enzyme 1 Chromosome Location Not Available
Enzyme 1 Locus Xq26.1
Enzyme 1 SNPs SNPJam Report Link Image
Enzyme 1 General References Not Available
Enzyme 1 Metabolite References Not Available
Enzyme 2 [top]
Enzyme 2 ID 2183
Enzyme 2 Name Guanine nucleotide-binding protein G(t) subunit alpha-1
Enzyme 2 Synonyms
  1. Transducin alpha-1 chain
Enzyme 2 Gene Name GNAT1
Enzyme 2 Protein Sequence >Guanine nucleotide-binding protein G(t) subunit alpha-1
MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLE
ECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMS
DIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGI
IETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMH
ESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYNGPNTYEDAGNYIK
VQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
Enzyme 2 Number of Residues 350
Enzyme 2 Molecular Weight 39965.3
Enzyme 2 Theoretical pI 5.47
Enzyme 2 GO Classification
Function
Process
Component
Enzyme 2 General Function Involved in acyl binding
Enzyme 2 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase
Enzyme 2 Pathways Not Available
Enzyme 2 Reactions Not Available
Enzyme 2 Pfam Domain Function
Enzyme 2 Signals
  • None
Enzyme 2 Transmembrane Regions
  • None
Enzyme 2 Essentiality Not Available
Enzyme 2 GenBank ID Protein 163773 Link Image
Enzyme 2 UniProtKB/Swiss-Prot ID P04695 Link Image
Enzyme 2 UniProtKB/Swiss-Prot Entry Name GNAT1_BOVIN Link Image
Enzyme 2 PDB ID 1TND Link Image
Enzyme 2 PDB File Show
Enzyme 2 3D Structure
Enzyme 2 Cellular Location Not Available
Enzyme 2 Gene Sequence >1053 bp
CCTTCACCTCCTGCCAGGACCATGGGGGCTGGGGCCAGCGCTGAGGAGAAGCACTCAAGG
GAGCTGGAAAAGAAGCTGAAAGAAGATGCTGAGAAAGATGCTCGAACCGTGAAACTGCTG
CTTCTGGGTGCCGGTGAATCCGGGAAGAGTACCATTGTCAAGCAGATGAAGATTATCCAC
CAGGACGGGTACTCACTGGAAGAGTGTCTTGAGTTCATTGCCATCATCTATGGCAACACG
CTACAGTCCATCCTGGCCATTGTGCGCGCCATGACCACACTCAACATCCAGTACGGAGAC
TCTGCGCGCCAGGACGACGCCCGAAAGCTGATGCACATGGCAGACACCATCGAGGAGGGC
ACGATGCCCAAGGAGATGTCAGACATCATCCAGCGGCTGTGGAAGGACTCCGGTATCCAG
GCCTGTTTCGACCGAGCCTCAGAGTACCAGCTCAACGACTCTGCTGGCTACTATCTCTCA
GACCTGGAGCGCCTGGTAACCCCGGGCTACGTGCCCACTGAACAGGATGTGCTGCGCTCC
CGTGTCAAGACCACGGGTATCATTGAGACGCAGTTCTCCTTCAAGGACCTCAACTTTCGG
ATGTTCGATGTGGGCGGGCAGCGCTCAGAGCGCAAGAAGTGGATCCACTGCTTCGAGGGG
GTGACCTGCATCATCTTCATCGCGGCGCTGAGCGCCTACGACATGGTGCTGGTGGAAGAC
GACGAAGTGAACCGCATGCACGAGAGCCTGCACCTGTTCAACAGTATCTGCAACCACCGC
TACTTCGCCACCACGTCCATCGTGCTCTTTCTCAACAAGAAGGACGTCTTCTCGGAGAAG
ATCAAAAAGGCGCACCTTAGCATCTGCTTTCCGGACTACAACGGGCCCAACACGTATGAG
GACGCCGGCAATTACATCAAGGTGCAATTCCTTGAGCTCAACATGCGACGCGACGTGAAG
GAGATCTATTCCCACATGACATGCGCCACCGACACGCAGAACGTCAAGTTTGTCTTCGAC
GCTGTCACCGACATCATCATCAAGGAGAACCTC
Enzyme 2 GenBank Gene ID K03253 Link Image
Enzyme 2 GeneCard ID GNAT1 Link Image
Enzyme 2 GenAtlas ID Not Available
Enzyme 2 HGNC ID Not Available
Enzyme 2 Chromosome Location Chromosome:3
Enzyme 2 Locus 3p21
Enzyme 2 SNPs SNPJam Report Link Image
Enzyme 2 General References
  1. [PubMed Link Image]
Enzyme 2 Metabolite References Not Available
Enzyme 3 [top]
Enzyme 3 ID 2184
Enzyme 3 Name Guanine nucleotide-binding protein G(t) subunit alpha-3
Enzyme 3 Synonyms
  1. Gustducin alpha-3 chain
Enzyme 3 Gene Name GNAT3
Enzyme 3 Protein Sequence >Guanine nucleotide-binding protein G(t) subunit alpha-3
MGIGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNG
YSEQECMEFKAVIYSNTLQSILAIVKAMATLEIDYVNPRSAEDQQQLCAMANTLEDGSMT
PELAEIIKRLWRDPGVQACFERASEYQLNDSAAYYLNDLDRIAAPGYVPNEQDVLHSRVK
TTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEV
NRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTKVHLSICFPEYTGPNTFEDAG
NYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
Enzyme 3 Number of Residues 354
Enzyme 3 Molecular Weight 40331.7
Enzyme 3 Theoretical pI 5.32
Enzyme 3 GO Classification
Function
Process
Component
Enzyme 3 General Function Involved in GTP binding
Enzyme 3 Specific Function Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction
Enzyme 3 Pathways Not Available
Enzyme 3 Reactions Not Available
Enzyme 3 Pfam Domain Function
Enzyme 3 Signals
  • None
Enzyme 3 Transmembrane Regions
  • None
Enzyme 3 Essentiality Not Available
Enzyme 3 GenBank ID Protein Not Available
Enzyme 3 UniProtKB/Swiss-Prot ID P0C7Q4 Link Image
Enzyme 3 UniProtKB/Swiss-Prot Entry Name GNAT3_BOVIN Link Image
Enzyme 3 PDB ID Not Available
Enzyme 3 Cellular Location Not Available
Enzyme 3 Gene Sequence Not Available
Enzyme 3 GenBank Gene ID AAFC03016846 Link Image
Enzyme 3 GeneCard ID GNAT3 Link Image
Enzyme 3 GenAtlas ID Not Available
Enzyme 3 HGNC ID Not Available
Enzyme 3 Chromosome Location Chromosome:7
Enzyme 3 Locus 7q21.11
Enzyme 3 SNPs SNPJam Report Link Image
Enzyme 3 General References
  1. [PubMed Link Image]
Enzyme 3 Metabolite References Not Available
Enzyme 4 [top]
Enzyme 4 ID 2185
Enzyme 4 Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
Enzyme 4 Synonyms Not Available
Enzyme 4 Gene Name GNG11
Enzyme 4 Protein Sequence >Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSREDPLVKGIPED
KNPFKEKGSCIIS
Enzyme 4 Number of Residues 73
Enzyme 4 Molecular Weight 8593.9
Enzyme 4 Theoretical pI 5.93
Enzyme 4 GO Classification
Function
Process
Component
Enzyme 4 General Function Involved in signal transducer activity
Enzyme 4 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
Enzyme 4 Pathways Not Available
Enzyme 4 Reactions Not Available
Enzyme 4 Pfam Domain Function
Enzyme 4 Signals
  • None
Enzyme 4 Transmembrane Regions
  • None
Enzyme 4 Essentiality Not Available
Enzyme 4 GenBank ID Protein 59858305 Link Image
Enzyme 4 UniProtKB/Swiss-Prot ID Q5E9F0 Link Image
Enzyme 4 UniProtKB/Swiss-Prot Entry Name GBG11_BOVIN Link Image
Enzyme 4 PDB ID Not Available
Enzyme 4 Cellular Location Not Available
Enzyme 4 Gene Sequence >222 bp
ATGCCGGCTCTTCACATCGAAGATCTGCCAGAAAAGGAAAAGCTGAAGATGGAAGTTGAG
CAACTTCGCAAAGAAGTTAAGTTGCAGAGACAGCAGGTGTCTAAATGTTCAGAAGAAATA
AAGAACTATATTGAAGAACGTTCTAGAGAGGATCCTCTGGTGAAAGGAATTCCAGAAGAC
AAGAATCCCTTTAAAGAAAAAGGCAGCTGCATTATTTCATGA
Enzyme 4 GenBank Gene ID BT020970 Link Image
Enzyme 4 GeneCard ID GNG11 Link Image
Enzyme 4 GenAtlas ID Not Available
Enzyme 4 HGNC ID Not Available
Enzyme 4 Chromosome Location Chromosome:7
Enzyme 4 Locus 7q21
Enzyme 4 SNPs SNPJam Report Link Image
Enzyme 4 General References
  1. [PubMed Link Image]
Enzyme 4 Metabolite References Not Available
Enzyme 5 [top]
Enzyme 5 ID 2186
Enzyme 5 Name Guanine nucleotide-binding protein G(t) subunit alpha-2
Enzyme 5 Synonyms
  1. Transducin alpha-2 chain
Enzyme 5 Gene Name GNAT2
Enzyme 5 Protein Sequence >Guanine nucleotide-binding protein G(t) subunit alpha-2
MGSGASAEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDG
YSPEECLEYKAIIYGNVLQSILAIIRAMPTLGIDYAEVSCVDNGRQLNNLADSIEEGTMP
PELVEVIRKLWKDGGVQACFDRAAEYQLNDSASYYLNQLDRITAPDYLPNEQDVLRSRVK
TTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEV
NRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYEDAG
NYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
Enzyme 5 Number of Residues 354
Enzyme 5 Molecular Weight 40143.5
Enzyme 5 Theoretical pI 5.00
Enzyme 5 GO Classification
Function
Process
Component
Enzyme 5 General Function Involved in GTP binding
Enzyme 5 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase
Enzyme 5 Pathways Not Available
Enzyme 5 Reactions Not Available
Enzyme 5 Pfam Domain Function
Enzyme 5 Signals
  • None
Enzyme 5 Transmembrane Regions
  • None
Enzyme 5 Essentiality Not Available
Enzyme 5 GenBank ID Protein 163779 Link Image
Enzyme 5 UniProtKB/Swiss-Prot ID P04696 Link Image
Enzyme 5 UniProtKB/Swiss-Prot Entry Name GNAT2_BOVIN Link Image
Enzyme 5 PDB ID Not Available
Enzyme 5 Cellular Location Not Available
Enzyme 5 Gene Sequence >1065 bp
TGCCGAGGAGGAGACGGATGAAAGATGGGGAGTGGAGCCAGTGCCGAGGACAAAGAACTG
GCCAAGAGGTCCAAAGAGCTAGAAAAGAAGCTGCAGGAGGATGCTGACAAGGAAGCCAAG
ACTGTCAAGCTGCTATTGCTGGGTGCTGGGGAGTCAGGAAAGAGCACTATCGTCAAACAG
ATGAAGATTATTCATCAGGATGGCTATTCGCCAGAAGAATGCCTGGAGTACAAGGCCATC
ATCTACGGCAACGTGCTGCAATCCATCTTGGCTATCATCCGGGCCATGCCCACACTGGGC
ATTGACTATGCTGAAGTGAGCTGTGTGGATAATGGGAGACAGCTCAACAACCTGGCTGAC
TCCATTGAAGAGGGCACCATGCCTCCTGAGCTAGTGGAGGTTATCAGGAAGTTGTGGAAG
GATGGTGGGGTGCAAGCCTGCTTTGACAGAGCTGCAGAGTACCAGCTCAATGACTCAGCA
TCTTACTACCTGAATCAATTAGACCGAATTACGGCCCCTGACTACCTCCCTAATGAGCAA
GATGTGCTACGATCCAGAGTCAAAACCACAGGCATCATTGAGACTAAGTTTTCTGTCAAG
GACTTAAACTTCCGGATGTTTGATGTGGGAGGGCAGAGATCAGAGAGAAAGAAGTGGATC
CACTGCTTTGAGGGAGTCACCTGCATCATTTTCTGTGCAGCCCTCAGCGCCTATGATATG
GTGCTGGTGGAAGATGACGAAGTGAATCGTATGCATGAGTCACTGCACCTGTTCAACAGC
ATATGTAACCACAAGTTCTTTGCGGCCACTTCCATTGTCCTCTTTCTCAACAAGAAGGAT
CTCTTTGAGGAAAAAATCAAGAAAGTCCATCTCAGCATTTGTTTTCCAGAGTATGATGGG
AACAACTCTTATGAGGATGCAGGGAATTATATCAAGAGTCAGTTCCTTGACCTCAACATG
AGAAAAGATGTCAAAGAAATCTACAGTCACATGACCTGTGCTACAGATACACAGAATGTC
AAATTTGTATTTGATGCAGTTACAGATATTATCATCAAAGAAAAC
Enzyme 5 GenBank Gene ID M11116 Link Image
Enzyme 5 GeneCard ID GNAT2 Link Image
Enzyme 5 GenAtlas ID Not Available
Enzyme 5 HGNC ID Not Available
Enzyme 5 Chromosome Location Chromosome:1
Enzyme 5 Locus 1p13.1
Enzyme 5 SNPs SNPJam Report Link Image
Enzyme 5 General References
  1. [PubMed Link Image]
Enzyme 5 Metabolite References Not Available
Enzyme 6 [top]
Enzyme 6 ID 2187
Enzyme 6 Name Guanine nucleotide binding protein-like 2 (Nucleolar)
Enzyme 6 Synonyms Not Available
Enzyme 6 Gene Name GNL2
Enzyme 6 Protein Sequence >Guanine nucleotide binding protein-like 2 (Nucleolar)
MVKPKYKGRSTINPSNASTNPDRVQGAGGHNMRDRATIRRLNMYRQKERRNSRGKVIKPL
QYQSTVASGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMDTVLKDPYKVVMKQSKLPMSL
LHDRIRPHNAKVHILDTESFETTFGPKAQRKRPNLFASDMQSLIENAETSTESYDQGKDR
DLVAEDTGVRNEAQEEIFKKGQSKRIWGELYKVIDSSDVVVQVLDARDPVGTRSPHIETY
LKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ
FGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLI
DCPGVVYPSEDSETDIVLKGVVQVEKIKTPEDHIGAVLERAKPEYISKTYKINSWENAED
FLEKLAFRTGKLLKGGEPNLRTVGKMVLSDWQRGRIPFFVKPPNAEPPAAPELPSSSSLE
VAAETTQNNPGEKVTETVGEESESILEKEKEEPRHCGIDSEMQQILARVRQNFGKINVAP
QFSGDDLVPLEMSDIDDELESLSAENEEEEEQEYPGDDEDESYAESQEEHAGRTTKAVIQ
ALDEKIAKYQRFLNKAKAKKFSAIRISKGLSEMVFAKSEGRKKGKAEEDVDDTAPPKKGK
KRKAQREEEQPDKTRRTLTSKERRREARQQRSRKVGIRYYETHNVKNRNRNKKKTTDSEG
QKHRHKKAKHKQ
Enzyme 6 Number of Residues 732
Enzyme 6 Molecular Weight 83468.2
Enzyme 6 Theoretical pI 10.01
Enzyme 6 GO Classification
Function
Process
Component
Enzyme 6 General Function Involved in GTP binding
Enzyme 6 Specific Function Not Available
Enzyme 6 Pathways Not Available
Enzyme 6 Reactions Not Available
Enzyme 6 Pfam Domain Function
Enzyme 6 Signals
  • None
Enzyme 6 Transmembrane Regions
  • None
Enzyme 6 Essentiality Not Available
Enzyme 6 GenBank ID Protein 82571622 Link Image
Enzyme 6 UniProtKB/Swiss-Prot ID Q2YDL0 Link Image
Enzyme 6 UniProtKB/Swiss-Prot Entry Name Q2YDL0_BOVIN Link Image
Enzyme 6 PDB ID Not Available
Enzyme 6 Cellular Location Not Available
Enzyme 6 Gene Sequence >2199 bp
ATGGTGAAGCCCAAGTACAAAGGACGGAGCACTATCAACCCCTCTAATGCCAGCACAAAT
CCCGATCGAGTGCAGGGAGCAGGAGGTCACAACATGAGGGACCGGGCCACAATTCGACGC
CTGAATATGTACAGACAGAAGGAGCGCAGGAACAGCCGTGGTAAAGTGATTAAGCCTCTG
CAGTATCAGTCAACAGTGGCTTCTGGCACAGTGGCAAGAGTGGAGCCAAACATTAAGTGG
TTTGGAAATACACGTGTGATTAAGCAGTCATCATTACAAAAATTTCAAGAGGAAATGGAC
ACAGTCTTGAAGGATCCATACAAAGTTGTCATGAAGCAAAGCAAGTTACCCATGTCTCTT
CTCCATGATCGAATCCGGCCTCATAATGCAAAGGTGCACATCCTTGATACTGAAAGCTTC
GAAACAACATTTGGCCCCAAAGCGCAGAGGAAGCGGCCAAATTTATTTGCAAGTGATATG
CAGTCACTTATAGAAAATGCAGAAACATCCACTGAGAGCTATGACCAGGGCAAGGATCGT
GACTTGGTAGCTGAAGACACTGGTGTGAGAAATGAAGCCCAAGAAGAGATATTTAAAAAG
GGACAGTCTAAAAGAATATGGGGTGAGCTCTACAAGGTGATAGATTCATCAGATGTTGTG
GTTCAAGTTCTTGATGCTAGAGATCCAGTGGGTACACGTTCCCCTCACATTGAGACTTAC
CTGAAAAAAGAGAAACCCTGGAAACATCTCATTTTTGTTCTTAACAAATGTGACCTTGTT
CCAACCTGGGCAACGAAACGATGGGTTGCCGTCCTCTCCCAGGATTACCCGACGCTTGCT
TTCCACGCGAGTCTTACTAACCCCTTTGGCAAAGGAGCGTTTATTCAGCTTCTGCGGCAG
TTTGGAAAGTTGCACACTGACAAGAAGCAGATCAGCGTGGGGTTCATTGGCTATCCAAAC
GTTGGCAAGAGCTCTGTGATAAACACACTGCGCTCCAAGAAGGTCTGCAACGTGGCCCCC
ATCGCAGGTGAAACAAAGGTCTGGCAGTACATTACCTTGATGCGTCGGATCTTCCTCATC
GACTGTCCGGGTGTGGTTTACCCCTCCGAGGACTCAGAGACGGACATTGTGCTGAAGGGA
GTCGTTCAAGTTGAAAAAATTAAGACTCCTGAAGACCACATTGGTGCTGTACTTGAACGA
GCAAAACCAGAGTATATCAGCAAGACGTACAAGATTAATTCTTGGGAGAACGCTGAGGAC
TTTCTGGAGAAGCTAGCTTTCCGGACAGGGAAGTTATTAAAGGGTGGAGAGCCCAACCTG
CGGACTGTGGGGAAGATGGTCCTCAGTGACTGGCAGAGGGGCCGGATTCCTTTCTTTGTC
AAGCCGCCCAATGCAGAACCCCCAGCAGCCCCCGAGCTTCCATCCTCCTCATCTTTGGAA
GTTGCCGCAGAAACAACCCAGAACAACCCAGGAGAGAAAGTCACGGAAACAGTAGGTGAG
GAGTCGGAATCCATCCTCGAGAAGGAAAAAGAGGAGCCCCGGCACTGTGGCATCGATTCA
GAAATGCAGCAGATTCTGGCGCGGGTCCGGCAGAACTTTGGCAAGATCAACGTTGCACCT
CAGTTTTCTGGGGATGACCTGGTTCCTCTGGAGATGTCCGATATCGATGACGAGCTGGAG
AGCCTTTCTGCGGAGAATGAGGAGGAGGAGGAACAGGAGTACCCAGGAGACGATGAGGAC
GAGTCTTATGCAGAGTCCCAGGAGGAACATGCGGGACGCACCACTAAGGCCGTTATTCAA
GCCCTGGATGAAAAGATCGCCAAGTACCAGAGGTTTTTAAACAAAGCCAAAGCTAAGAAG
TTTTCAGCAATCAGGATATCCAAGGGACTGAGTGAAATGGTTTTTGCAAAATCCGAAGGA
CGAAAAAAAGGAAAAGCTGAAGAAGATGTAGATGATACAGCACCTCCCAAAAAGGGAAAG
AAGAGGAAGGCCCAGAGGGAAGAGGAGCAGCCAGACAAAACCCGCAGGACGCTTACGTCT
AAGGAGAGGAGGCGAGAAGCACGGCAGCAGCGATCTAGAAAAGTCGGCATACGCTACTAT
GAAACACACAATGTGAAGAATAGGAACAGGAACAAAAAGAAGACCACCGACTCAGAAGGG
CAGAAACACAGACACAAGAAAGCCAAACATAAGCAGTAA
Enzyme 6 GenBank Gene ID BC110174 Link Image
Enzyme 6 GeneCard ID GNL2 Link Image
Enzyme 6 GenAtlas ID Not Available
Enzyme 6 HGNC ID Not Available
Enzyme 6 Chromosome Location Chromosome:1
Enzyme 6 Locus 1p34.3
Enzyme 6 SNPs SNPJam Report Link Image
Enzyme 6 General References Not Available
Enzyme 6 Metabolite References Not Available
Enzyme 7 [top]
Enzyme 7 ID 2188
Enzyme 7 Name Guanine nucleotide-binding protein subunit alpha-11
Enzyme 7 Synonyms
  1. G-protein subunit alpha-11
  2. G alpha-11
  3. G-protein subunit GL2 alpha
Enzyme 7 Gene Name GNA11
Enzyme 7 Protein Sequence >Guanine nucleotide-binding protein subunit alpha-11
MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR
IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEK
VTTFEHRYVSAIKTLWNDPGIQECYDRRREYQLSDSAKYYLTDVDRIATSGYLPTQQDVL
RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV
ESDNENRMEESKALFRTIVTYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQR
DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
Enzyme 7 Number of Residues 359
Enzyme 7 Molecular Weight 42069.8
Enzyme 7 Theoretical pI 6.03
Enzyme 7 GO Classification
Function
Process
Component
Enzyme 7 General Function Involved in GTP binding
Enzyme 7 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems
Enzyme 7 Pathways Not Available
Enzyme 7 Reactions Not Available
Enzyme 7 Pfam Domain Function
Enzyme 7 Signals
  • None
Enzyme 7 Transmembrane Regions
  • None
Enzyme 7 Essentiality Not Available
Enzyme 7 GenBank ID Protein 217568 Link Image
Enzyme 7 UniProtKB/Swiss-Prot ID P38409 Link Image
Enzyme 7 UniProtKB/Swiss-Prot Entry Name GNA11_BOVIN Link Image
Enzyme 7 PDB ID Not Available
Enzyme 7 Cellular Location Not Available
Enzyme 7 Gene Sequence >1062 bp
ATGGCGTGTTGCCTGAGCGATGAGGTGAAGGAGTCCAAGCGGATCAACGCCGAGATCGAG
AAGCAGCTGCGGCGGGACAAGCGCGACGCCCGGCGCGAGCTCAAGCTGCTGCTGCTCGGC
ACGGGCGAGAGCGGGAAGAGCACGTTCATCAAGCAGATGCGCATCATCCACGGGGCGGGC
TACTCAGAGGAGGACAAGCGGGGCTTCACCAAACTGGTGTACCAGAACATCTTCACCGCC
ATGCAGGCCATGATCCGCGCCATGGAAACGCTGAAGATCCTCTACAAGTACGAGCAGAAC
AAGGCCAACGCACTCCTGATCCGGGAGGTGGATGTGGAAAAGGTGACGACCTTCGAGCAC
CGGTACGTGAGCGCCATCAAGACCCTGTGGAACGACCCCGGCATCCAGGAGTGCTATGAC
CGCCGGCGCGAGTACCAGCTCTCGGACTCCGCCAAGTACTACCTGACGGACGTGGACCGC
ATTGCCACCTCAGGCTACCTGCCCACCCAGCAGGACGTGCTGCGGGTGCGCGTGCCCACC
ACGGGCATCATCGAATACCCCTTCGACCTGGAGAACATCATCTTCAGGATGGTGGATGTG
GGGGGCCAGAGGTCCGAGCGGAGGAAGTGGATTCACTGCTTTGAGAACGTGACGTCCATC
ATGTTCCTTGTGGCCCTTAGTGAGTACGACCAAGTGCTGGTGGAATCGGACAACGAGAAC
CGCATGGAGGAGAGCAAGGCGCTGTTCCGGACCATCGTCACCTACCCCTGGTTCCAGAAC
TCATCCGTCATCCTCTTCCTCAACAAGAAGGACCTGCTGGAGGACAAGATCCTCCACTCC
CACCTGGTGGACTACTTCCCGGAGTTCGACGGCCCCCAGCGGGACGCGCAGGCTGCCCGG
GAGTTCATCCTGAAGATGTTCGTGGACCTAAACCCCGACAGCGACAAGATCATCTACTCG
CACTTCACCTGCGCCACCGACACAGAGAACATCCGTTTCGTCTTCGCTGCTGTCAAGGAC
ACCATCCTGCAGCTCAACCTGAAGGAGTACAACCTGGTGTGA
Enzyme 7 GenBank Gene ID D90336 Link Image
Enzyme 7 GeneCard ID GNA11 Link Image
Enzyme 7 GenAtlas ID Not Available
Enzyme 7 HGNC ID Not Available
Enzyme 7 Chromosome Location Chromosome:1
Enzyme 7 Locus 19p13.3
Enzyme 7 SNPs SNPJam Report Link Image
Enzyme 7 General References
  1. [PubMed Link Image]
Enzyme 7 Metabolite References Not Available
Enzyme 8 [top]
Enzyme 8 ID 2189
Enzyme 8 Name Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
Enzyme 8 Synonyms Not Available
Enzyme 8 Gene Name GNAI3
Enzyme 8 Protein Sequence >Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG
YSEEECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT
PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRVK
TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKRSSLTICYPEYTGSNTYEEAA
AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY
Enzyme 8 Number of Residues 354
Enzyme 8 Molecular Weight 40535.8
Enzyme 8 Theoretical pI 5.37
Enzyme 8 GO Classification
Function
Process
Component
Enzyme 8 General Function Involved in GTP binding
Enzyme 8 Specific Function Not Available
Enzyme 8 Pathways Not Available
Enzyme 8 Reactions Not Available
Enzyme 8 Pfam Domain Function
Enzyme 8 Signals
  • None
Enzyme 8 Transmembrane Regions
  • None
Enzyme 8 Essentiality Not Available
Enzyme 8 GenBank ID Protein 73586987 Link Image
Enzyme 8 UniProtKB/Swiss-Prot ID Q3ZCA7 Link Image
Enzyme 8 UniProtKB/Swiss-Prot Entry Name Q3ZCA7_BOVIN Link Image
Enzyme 8 PDB ID 1CIP Link Image
Enzyme 8 PDB File Show
Enzyme 8 3D Structure
Enzyme 8 Cellular Location Not Available
Enzyme 8 Gene Sequence >1065 bp
ATGGGGTGCACGTTGAGCGCCGAAGATAAGGCGGCGGTGGAGCGAAGCAAGATGATCGAC
CGCAACTTGCGGGAGGACGGGGAGAAAGCGGCCAAAGAAGTGAAGCTGCTGCTACTCGGT
GCTGGAGAATCTGGCAAAAGCACTATTGTGAAACAGATGAAAATCATTCATGAAGATGGC
TATTCAGAGGAAGAATGTAAACAATATAAAGTAGTTGTCTACAGCAATACTATACAGTCT
ATCATTGCAATCATAAGAGCCATGGGACGGCTAAAGATTGACTTTGGGGAAGCTGCCAGA
GCAGACGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCCGAAGAAGGAGTCATGACT
CCAGAATTAGCAGGAGTGATTAAACGGTTATGGCGAGATGGTGGGGTGCAAGCTTGCTTC
AGCAGATCCAGGGAATATCAGCTCAATGATTCGGCTTCATATTACCTAAATGATTTGGAT
AGAATATCCCAAACCAACTACATTCCAACTCAGCAAGACGTTTTGCGGACGAGAGTGAAG
ACCACAGGCATTGTGGAAACACATTTCACTTTCAAAGACCTATACTTCAAGATGTTTGAT
GTAGGTGGCCAAAGATCAGAACGAAAAAAGTGGATTCACTGTTTTGAGGGAGTGACAGCA
ATTATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAAGATGAGGAGATG
AACCGAATGCATGAAAGCATGAAACTCTTTGACAGCATTTGTAACAACAAATGGTTTACA
GACACTTCGATCATTCTGTTTCTCAACAAGAAAGATCTTTTTGAGGAAAAAATAAAGAGG
AGTTCATTAACTATCTGTTATCCAGAATACACAGGTTCCAACACATATGAAGAAGCAGCT
GCGTACATTCAGTGCCAGTTTGAAGACCTGAACAGAAGAAAAGATACCAAGGAGATCTAT
ACCCACTTCACCTGTGCCACAGACACCAAGAACGTGCAGTTTGTTTTTGATGCTGTAACA
GATGTCATCATTAAAAACAACTTAAAGGAATGTGGGCTTTATTGA
Enzyme 8 GenBank Gene ID BC102645 Link Image
Enzyme 8 GeneCard ID GNAI3 Link Image
Enzyme 8 GenAtlas ID Not Available
Enzyme 8 HGNC ID Not Available
Enzyme 8 Chromosome Location Chromosome:1
Enzyme 8 Locus 1p13
Enzyme 8 SNPs SNPJam Report Link Image
Enzyme 8 General References
  1. [PubMed Link Image]
Enzyme 8 Metabolite References Not Available
Enzyme 9 [top]
Enzyme 9 ID 2190
Enzyme 9 Name Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
Enzyme 9 Synonyms
  1. Transducin beta chain 2
  2. G protein subunit beta-2
Enzyme 9 Gene Name GNB2
Enzyme 9 Protein Sequence >Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGRIQMRTRRTLRGHLAKIYA
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNI
CSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGF
AGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA
FTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM
KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
Enzyme 9 Number of Residues 340
Enzyme 9 Molecular Weight 37330.6
Enzyme 9 Theoretical pI 5.85
Enzyme 9 GO Classification
Function
Process
Component
Enzyme 9 General Function Involved in GTPase activity
Enzyme 9 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
Enzyme 9 Pathways Not Available
Enzyme 9 Reactions Not Available
Enzyme 9 Pfam Domain Function
Enzyme 9 Signals
  • None
Enzyme 9 Transmembrane Regions
  • None
Enzyme 9 Essentiality Not Available
Enzyme 9 GenBank ID Protein 146186921 Link Image
Enzyme 9 UniProtKB/Swiss-Prot ID P11017 Link Image
Enzyme 9 UniProtKB/Swiss-Prot Entry Name GBB2_BOVIN Link Image
Enzyme 9 PDB ID Not Available
Enzyme 9 Cellular Location Not Available
Enzyme 9 Gene Sequence >1023 bp
ATGAGTGAGCTGGAGCAACTGAGACAGGAGGCCGAGCAGCTCCGGAACCAGATCCGGGAT
GCCCGAAAAGCATGTGGGGATTCAACACTGACCCAGATCACAGCTGGGCTGGACCCAGTG
GGGAGAATCCAGATGAGGACACGGAGGACCCTCCGTGGGCACCTGGCCAAAATCTATGCC
ATGCACTGGGGGACAGACTCAAGGCTGCTGGTCAGCGCCTCCCAGGACGGCAAGCTCATC
ATTTGGGACAGCTACACCACCAACAAGGTCCACGCCATCCCGCTGCGCTCCTCCTGGGTC
ATGACCTGTGCCTACGCGCCCTCAGGGAACTTCGTGGCCTGCGGGGGACTGGACAACATA
TGCTCCATCTACAGCCTCAAGACCCGTGAGGGCAATGTCAGGGTCAGCCGGGAGCTGCCT
GGCCACACCGGGTACCTGTCATGCTGCCGCTTTCTGGATGACAACCAAATCATCACCAGC
TCTGGGGACACCACCTGTGCCCTGTGGGACATTGAGACCGGCCAGCAGACTGTGGGCTTT
GCTGGACATAGTGGTGATGTGATGTCCCTGTCCCTGGCCCCCGACGGCCGCACCTTTGTG
TCAGGCGCCTGCGACGCCTCCATCAAGCTGTGGGACGTGCGGGACTCCATGTGCCGACAG
ACCTTCATCGGCCACGAATCCGACATCAACGCCGTGGCTTTCTTCCCCAACGGCTACGCC
TTCACCACGGGCTCTGATGACGCCACATGCCGCCTCTTTGACTTGCGGGCCGACCAGGAG
CTCCTCATGTATTCGCACGACAACATCATCTGCGGCATCACCTCTGTTGCCTTCTCGCGC
AGCGGCAGGCTGCTGCTCGCGGGCTACGACGACTTCAACTGCAACATCTGGGATGCCATG
AAGGGCGACCGTGCAGGTGTCCTCGCCGGCCATGACAACCGTGTGAGCTGCCTCGGGGTC
ACTGACGATGGCATGGCTGTGGCCACAGGTTCCTGGGACTCCTTCCTCAAGATCTGGAAC
TAA
Enzyme 9 GenBank Gene ID BC140489 Link Image
Enzyme 9 GeneCard ID GNB2 Link Image
Enzyme 9 GenAtlas ID Not Available
Enzyme 9 HGNC ID Not Available
Enzyme 9 Chromosome Location Chromosome:7
Enzyme 9 Locus 7q21.3-q22.1|7q22
Enzyme 9 SNPs SNPJam Report Link Image
Enzyme 9 General References
  1. [PubMed Link Image]
Enzyme 9 Metabolite References Not Available
Enzyme 10 [top]
Enzyme 10 ID 2191
Enzyme 10 Name Guanine nucleotide-binding protein subunit alpha-14
Enzyme 10 Synonyms
  1. G-protein subunit alpha-14
  2. G alpha-14
  3. G-protein subunit GL1 alpha
Enzyme 10 Gene Name GNA14
Enzyme 10 Protein Sequence >Guanine nucleotide-binding protein subunit alpha-14
MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHG
SGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLKIQYVCEQNKENAQLIREVEVDKVSTL
SRDQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIAMPAFVPTQQDVLRVRV
PTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDN
ENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKA
ARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV
Enzyme 10 Number of Residues 355
Enzyme 10 Molecular Weight 41498.2
Enzyme 10 Theoretical pI 5.86
Enzyme 10 GO Classification
Function
Process
Component
Enzyme 10 General Function Involved in GTP binding
Enzyme 10 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems
Enzyme 10 Pathways Not Available
Enzyme 10 Reactions Not Available
Enzyme 10 Pfam Domain Function
Enzyme 10 Signals
  • None
Enzyme 10 Transmembrane Regions
  • None
Enzyme 10 Essentiality Not Available
Enzyme 10 GenBank ID Protein 217566 Link Image
Enzyme 10 UniProtKB/Swiss-Prot ID P38408 Link Image
Enzyme 10 UniProtKB/Swiss-Prot Entry Name GNA14_BOVIN Link Image
Enzyme 10 PDB ID Not Available
Enzyme 10 Cellular Location Not Available
Enzyme 10 Gene Sequence >1068 bp
ATGGCCGGCTGCTGCTGCCTGTCAGCGGAGGAGAAGGAGTCGCAGCGCATCAGCGCCGAG
ATCGAGCGGCAGCTTCGCCGGGACAAGAAGGACGCGCGCCGCGAGCTCAAGTTGCTGCTG
CTGGGAACTGGTGAAAGTGGCAAAAGCACCTTTATCAAGCAGATGAGAATCATCCACGGG
TCTGGGTACAGCGACGAAGACAGAAAGGGGTTCACGAAGCTGGTTTACCAAAACATATTC
ACTGCCATGCAAGCCATGATCAGAGCCATGGACACCCTGAAGATACAGTACGTGTGTGAG
CAGAATAAGGAAAATGCCCAGCTAATCAGAGAAGTGGAAGTAGACAAGGTGTCCACACTC
TCCAGGGACCAGGTGGAGGCCATCAAGCAGCTGTGGCAGGATCCTGGAATCCAGGAGTGC
TACGATCGGAGGCGGGAGTACCAACTGTCAGACTCTGCCAAATATTACCTGACGGACATT
GACCGGATCGCCATGCCAGCGTTCGTGCCCACACAGCAGGATGTGCTCCGTGTCCGAGTG
CCCACCACTGGCATCATTGAGTATCCGTTTGACCTGGAAAACATCATCTTTCGGATGGTG
GATGTTGGTGGCCAGCGATCTGAAAGACGGAAATGGATTCACTGCTTTGAGAGTGTCACC
TCCATTATTTTTTTGGTTGCTCTGAGTGAATATGACCAGGTCCTGGCTGAGTGTGACAAT
GAGAACCGCATGGAAGAGAGTAAAGCCTTATTTAAAACTATCATCACCTACCCCTGGTTT
CTGAACTCATCAGTGATTCTGTTCTTAAACAAGAAGGATCTTTTGGAAGAGAAAATCATG
TACTCTCATCTAATTAGCTATTTTCCAGAATACACTGGACCAAAGCAAGACGTCAAAGCT
GCCAGAGATTTCATCCTGAAGCTTTATCAAGATCAGAATCCTGACAAAGAGAAGGTCATC
TACTCCCACTTCACATGTGCTACAGACACAGAGAATATCCGCTTTGTGTTTGCTGCTGTG
AAAGACACAATCCTACAACTGAACCTGAGGGAATTCAACCTGGTTTAA
Enzyme 10 GenBank Gene ID D90335 Link Image
Enzyme 10 GeneCard ID GNA14 Link Image
Enzyme 10 GenAtlas ID Not Available
Enzyme 10 HGNC ID Not Available
Enzyme 10 Chromosome Location Chromosome:9
Enzyme 10 Locus 9q21
Enzyme 10 SNPs SNPJam Report Link Image
Enzyme 10 General References
  1. [PubMed Link Image]
Enzyme 10 Metabolite References Not Available
Enzyme 11 [top]
Enzyme 11 ID 2192
Enzyme 11 Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Enzyme 11 Synonyms
  1. Gamma-S1
Enzyme 11 Gene Name GNG12
Enzyme 11 Protein Sequence >Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
MSSKTASTNNIAQARRTVQQLRMEASIERIKVSKASADLMSYCEEHARNDPLLMGIPTSE
NPFKDKKTCTIL
Enzyme 11 Number of Residues 72
Enzyme 11 Molecular Weight 8057.2
Enzyme 11 Theoretical pI 9.38
Enzyme 11 GO Classification
Function
Process
Component
Enzyme 11 General Function Involved in signal transducer activity
Enzyme 11 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
Enzyme 11 Pathways Not Available
Enzyme 11 Reactions Not Available
Enzyme 11 Pfam Domain Function
Enzyme 11 Signals
  • None
Enzyme 11 Transmembrane Regions
  • None
Enzyme 11 Essentiality Not Available
Enzyme 11 GenBank ID Protein 1109682 Link Image
Enzyme 11 UniProtKB/Swiss-Prot ID Q28024 Link Image
Enzyme 11 UniProtKB/Swiss-Prot Entry Name GBG12_BOVIN Link Image
Enzyme 11 PDB ID Not Available
Enzyme 11 Cellular Location Not Available
Enzyme 11 Gene Sequence >219 bp
ATGTCGAGCAAGACAGCCAGTACCAACAACATTGCCCAGGCACGGAGGACTGTGCAGCAG
TTGAGAATGGAAGCCTCCATTGAGAGAATAAAGGTTTCAAAGGCATCAGCAGACCTCATG
TCCTACTGTGAGGAACATGCCAGGAATGACCCTCTGCTGATGGGGATACCAACTTCAGAA
AACCCCTTCAAGGATAAGAAGACCTGCACCATCTTATAG
Enzyme 11 GenBank Gene ID U37561 Link Image
Enzyme 11 GeneCard ID GNG12 Link Image
Enzyme 11 GenAtlas ID Not Available
Enzyme 11 HGNC ID Not Available
Enzyme 11 Chromosome Location Chromosome:1
Enzyme 11 Locus 1p31.3
Enzyme 11 SNPs SNPJam Report Link Image
Enzyme 11 General References
  1. [PubMed Link Image]
Enzyme 11 Metabolite References Not Available
Enzyme 12 [top]
Enzyme 12 ID 2193
Enzyme 12 Name Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Enzyme 12 Synonyms
  1. Adenylate cyclase-stimulating G alpha protein
Enzyme 12 Gene Name GNAS
Enzyme 12 Protein Sequence >Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM
RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA
NPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD
KIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK
VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY
PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
Enzyme 12 Number of Residues 394
Enzyme 12 Molecular Weight 45708.2
Enzyme 12 Theoretical pI 5.40
Enzyme 12 GO Classification
Function
Process
Component
Enzyme 12 General Function Involved in GTP binding
Enzyme 12 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase:it activates the cyclase in response to beta-adrenergic stimuli
Enzyme 12 Pathways Not Available
Enzyme 12 Reactions Not Available
Enzyme 12 Pfam Domain Function
Enzyme 12 Signals
  • None
Enzyme 12 Transmembrane Regions
  • None
Enzyme 12 Essentiality Not Available
Enzyme 12 GenBank ID Protein 402 Link Image
Enzyme 12 UniProtKB/Swiss-Prot ID P04896 Link Image
Enzyme 12 UniProtKB/Swiss-Prot Entry Name GNAS2_BOVIN Link Image
Enzyme 12 PDB ID 1U0H Link Image
Enzyme 12 PDB File Show
Enzyme 12 3D Structure
Enzyme 12 Cellular Location Not Available
Enzyme 12 Gene Sequence >1185 bp
ATGGGCTGTCTCGGAAACAGCAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGC
GAGGCCAACAAGAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGCCACG
CACCGTCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAAATG
AGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCA
AGGAGCAACAGCGATGGTGAGAAGGCCACCAAAGTGCAGGACATCAAAAACAACCTGAAA
GAGGCCATTGAAACCATCGTGGCCGCCATGAGCAACCTGGTGCCCCCTGTGGAGCTGGCC
AACCCAGAGAACCAGTTCAGAGTGGATTACATTCTGAGCGTGATGAACGTGCCGGACTTT
GATTTCCCTCCCGAATTCTACGAGCATGCCAAGGCTCTCTGGGAGGATGAAGGGGTGCGT
GCCTGCTATGAGCGCTCCAACGAGTACCAGCTGATTGACTGCGCCCAGTACTTCCTGGAC
AAGATTGATGTCATCAAGCAGGATGACTACGTGCCCAGCGACCAGGATCTGCTCCGCTGC
CGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCAC
ATGTTTGACGTGGGCGGCCAGCGCGATGAACGCCGCAAATGGATCCAATGCTTCAATGAT
GTGACTGCCATCATCTTCGTGGTTGCCAGCAGCAGCTACAACATGGTCATTCGGGAGGAC
AACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAATAACAGA
TGGCTGCGCACCATCTCTGTGATTCTGTTCCTCAACAAGCAAGATCTGCTGGCTGAGAAA
GTCCTTGCTGGAAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACT
CCTGAGGATGCGACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTC
ATTCGAGATGAATTTCTGAGAATCAGCACTGCTAGTGGAGACGGGCGCCACTACTGCTAC
CCTCACTTCACCTGCGCTGTGGACACCGAGAACATCCGCCGTGTGTTCAACGACTGCCGT
GACATCATCCAGCGCATGCACCTCCGTCAGTATGAGCTGCTCTAA
Enzyme 12 GenBank Gene ID X03404 Link Image
Enzyme 12 GeneCard ID GNAS Link Image
Enzyme 12 GenAtlas ID Not Available
Enzyme 12 HGNC ID Not Available
Enzyme 12 Chromosome Location Chromosome:2
Enzyme 12 Locus 20q13.3
Enzyme 12 SNPs SNPJam Report Link Image
Enzyme 12 General References
  1. [PubMed Link Image]
Enzyme 12 Metabolite References Not Available
Enzyme 13 [top]
Enzyme 13 ID 2194
Enzyme 13 Name Guanine nucleotide-binding protein G(i), alpha-1 subunit
Enzyme 13 Synonyms
  1. Adenylate cyclase-inhibiting G alpha protein
Enzyme 13 Gene Name GNAI1
Enzyme 13 Protein Sequence >Guanine nucleotide-binding protein G(i), alpha-1 subunit
MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG
YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT
AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVK
TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA
AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
Enzyme 13 Number of Residues 354
Enzyme 13 Molecular Weight 40360.7
Enzyme 13 Theoretical pI 5.76
Enzyme 13 GO Classification
Function
Process
Component
Enzyme 13 General Function Involved in GTP binding
Enzyme 13 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase:they inhibit the cyclase in response to beta-adrenergic stimuli
Enzyme 13 Pathways Not Available
Enzyme 13 Reactions Not Available
Enzyme 13 Pfam Domain Function
Enzyme 13 Signals
  • None
Enzyme 13 Transmembrane Regions
  • None
Enzyme 13 Essentiality Not Available
Enzyme 13 GenBank ID Protein 391 Link Image
Enzyme 13 UniProtKB/Swiss-Prot ID P63097 Link Image
Enzyme 13 UniProtKB/Swiss-Prot Entry Name GNAI1_BOVIN Link Image
Enzyme 13 PDB ID 1CIP Link Image
Enzyme 13 PDB File Show
Enzyme 13 3D Structure
Enzyme 13 Cellular Location Not Available
Enzyme 13 Gene Sequence >1065 bp
ATGGGCTGTACGCTGAGCGCCGAGGACAAGGCGGCGGTGGAGCGGAGTAAGATGATCGAC
CGGAACCTCCGCGAGGATGGCGAGAAGGCGGCGCGCGAGGTCAAGCTGCTGCTGCTCGGT
GCTGGTGAATCTGGGAAAAGTACAATTGTGAAGCAAATGAAAATTATCCATGAAGCTGGT
TATTCAGAAGAGGAATGTAAGCAGTACAAAGCTGTGGTCTACAGTAACACCATCCAGTCA
ATTATCGCTATCATTAGGGCCATGGGGAGATTGAAGATTGACTTCGGTGACTCAGCCCGG
GCGGATGATGCCCGCCAACTCTTTGTGCTTGCTGGCGCTGCAGAGGAAGGTTTTATGACT
GCAGAACTTGCTGGAGTTATAAAGAGACTTTGGAAAGACAGTGGTGTACAAGCCTGCTTC
AACAGATCCCGAGAGTACCAGCTTAATGATTCTGCAGCATACTATTTGAATGATTTGGAC
AGAATTGCACAACCAAATTATATTCCAACTCAACAAGATGTTCTCAGAACTCGAGTGAAA
ACCACAGGAATTGTTGAGACCCATTTTACTTTCAAAGATCTTCATTTTAAAATGTTTGAT
GTGGGAGGACAGAGATCTGAGCGGAAGAAATGGATTCATTGCTTCGAAGGAGTGACCGCC
ATCATCTTCTGTGTGGCGCTGAGTGACTATGACCTGGTTCTAGCTGAAGATGAAGAAATG
AACCGAATGCATGAAAGCATGAAGTTATTCGACAGCATATGTAACAACAAATGGTTTACA
GATACATCTATTATACTTTTTCTGAACAAGAAGGATCTCTTTGAAGAAAAAATCAAGAAG
AGCCCTCTCACTATATGCTATCCAGAATATGCAGGCTCAAACACATATGAAGAGGCAGCT
GCGTACATTCAGTGTCAGTTTGAAGACCTCAATAAGAGAAAGGACACAAAGGAAATATAC
ACCCACTTCACGTGCGCCACGGACACCAAGAACGTGCAGTTCGTCTTTGATGCCGTAACA
GACGTCATCATAAAAAATAACCTAAAAGACTGTGGTCTCTTCTGA
Enzyme 13 GenBank Gene ID X03642 Link Image
Enzyme 13 GeneCard ID GNAI1 Link Image
Enzyme 13 GenAtlas ID Not Available
Enzyme 13 HGNC ID Not Available
Enzyme 13 Chromosome Location Chromosome:7
Enzyme 13 Locus 7q21
Enzyme 13 SNPs SNPJam Report Link Image
Enzyme 13 General References
  1. [PubMed Link Image]
Enzyme 13 Metabolite References Not Available
Enzyme 14 [top]
Enzyme 14 ID 2195
Enzyme 14 Name Guanine nucleotide binding protein alpha subunit
Enzyme 14 Synonyms Not Available
Enzyme 14 Gene Name Gnas
Enzyme 14 Protein Sequence >Guanine nucleotide binding protein alpha subunit
ATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNN
LKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEG
VRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVN
FHMFDVGGQRDERRKWIQCFNDVTAIIFVVA
Enzyme 14 Number of Residues 211
Enzyme 14 Molecular Weight 23993.9
Enzyme 14 Theoretical pI 4.54
Enzyme 14 GO Classification
Function
Process
Component
Enzyme 14 General Function Involved in GTP binding
Enzyme 14 Specific Function Not Available
Enzyme 14 Pathways Not Available
Enzyme 14 Reactions Not Available
Enzyme 14 Pfam Domain Function
Enzyme 14 Signals
  • None
Enzyme 14 Transmembrane Regions
  • None
Enzyme 14 Essentiality Not Available
Enzyme 14 GenBank ID Protein 37908028 Link Image
Enzyme 14 UniProtKB/Swiss-Prot ID Q6U8D6 Link Image
Enzyme 14 UniProtKB/Swiss-Prot Entry Name Q6U8D6_BOVIN Link Image
Enzyme 14 PDB ID 1U0H Link Image
Enzyme 14 PDB File Show
Enzyme 14 3D Structure
Enzyme 14 Cellular Location Not Available
Enzyme 14 Gene Sequence Not Available
Enzyme 14 GenBank Gene ID AY376066 Link Image
Enzyme 14 GeneCard ID Gnas Link Image
Enzyme 14 GenAtlas ID Not Available
Enzyme 14 HGNC ID Not Available
Enzyme 14 Chromosome Location Chromosome:2
Enzyme 14 Locus 20q13.3
Enzyme 14 SNPs SNPJam Report Link Image
Enzyme 14 General References
  1. [PubMed Link Image]
Enzyme 14 Metabolite References Not Available
Enzyme 15 [top]
Enzyme 15 ID 2196
Enzyme 15 Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
Enzyme 15 Synonyms Not Available
Enzyme 15 Gene Name GNG3
Enzyme 15 Protein Sequence >Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT
SENPFREKKFFCALL
Enzyme 15 Number of Residues 75
Enzyme 15 Molecular Weight 8304.7
Enzyme 15 Theoretical pI 7.93
Enzyme 15 GO Classification
Function
Process
Component
Enzyme 15 General Function Involved in signal transducer activity
Enzyme 15 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
Enzyme 15 Pathways Not Available
Enzyme 15 Reactions Not Available
Enzyme 15 Pfam Domain Function
Enzyme 15 Signals
  • None
Enzyme 15 Transmembrane Regions
  • None
Enzyme 15 Essentiality Not Available
Enzyme 15 GenBank ID Protein 163084 Link Image
Enzyme 15 UniProtKB/Swiss-Prot ID P63214 Link Image
Enzyme 15 UniProtKB/Swiss-Prot Entry Name GBG3_BOVIN Link Image
Enzyme 15 PDB ID Not Available
Enzyme 15 Cellular Location Not Available
Enzyme 15 Gene Sequence >228 bp
ATGAAAGGGGAGACCCCTGTGAACAGCACTATGAGTATTGGGCAAGCCCGCAAGATGGTG
GAACAGCTTAAGATTGAAGCCAGCTTGTGCCGGATAAAGGTGTCCAAGGCAGCAGCAGAC
CTGATGACTTACTGTGATGCCCACGCCTGTGAGGATCCCCTCATCACCCCTGTGCCCACT
TCGGAGAACCCCTTCCGGGAGAAGAAATTCTTCTGTGCTCTCCTCTGA
Enzyme 15 GenBank Gene ID M58349 Link Image
Enzyme 15 GeneCard ID GNG3 Link Image
Enzyme 15 GenAtlas ID Not Available
Enzyme 15 HGNC ID Not Available
Enzyme 15 Chromosome Location Chromosome:1
Enzyme 15 Locus 11p11
Enzyme 15 SNPs SNPJam Report Link Image
Enzyme 15 General References
  1. [PubMed Link Image]
Enzyme 15 Metabolite References Not Available
Enzyme 16 [top]
Enzyme 16 ID 2197
Enzyme 16 Name Guanine nucleotide-binding protein, beta-1 subunit
Enzyme 16 Synonyms Not Available
Enzyme 16 Gene Name GNB1
Enzyme 16 Protein Sequence >Guanine nucleotide-binding protein, beta-1 subunit
LDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHW
GTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSI
YNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGH
TGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT
GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKAD
RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
Enzyme 16 Number of Residues 337
Enzyme 16 Molecular Weight 37029.2
Enzyme 16 Theoretical pI 6.08
Enzyme 16 GO Classification
Function
Process
Component
Enzyme 16 General Function Involved in activation of phospholipase C activity by G
Enzyme 16 Specific Function Not Available
Enzyme 16 Pathways Not Available
Enzyme 16 Reactions Not Available
Enzyme 16 Pfam Domain Function
Enzyme 16 Signals
  • None
Enzyme 16 Transmembrane Regions
  • None
Enzyme 16 Essentiality Not Available
Enzyme 16 GenBank ID Protein 152941214 Link Image
Enzyme 16 UniProtKB/Swiss-Prot ID A7E3V7 Link Image
Enzyme 16 UniProtKB/Swiss-Prot Entry Name A7E3V7_BOVIN Link Image
Enzyme 16 PDB ID 1OMW Link Image
Enzyme 16 PDB File Show
Enzyme 16 3D Structure
Enzyme 16 Cellular Location Not Available
Enzyme 16 Gene Sequence Not Available
Enzyme 16 GenBank Gene ID BT030728 Link Image
Enzyme 16 GeneCard ID GNB1 Link Image
Enzyme 16 GenAtlas ID Not Available
Enzyme 16 HGNC ID Not Available
Enzyme 16 Chromosome Location Chromosome:1
Enzyme 16 Locus 1p36.33
Enzyme 16 SNPs SNPJam Report Link Image
Enzyme 16 General References
  1. [PubMed Link Image]
Enzyme 16 Metabolite References Not Available
Enzyme 17 [top]
Enzyme 17 ID 2198
Enzyme 17 Name Guanine nucleotide-binding protein-like 3-like protein
Enzyme 17 Synonyms Not Available
Enzyme 17 Gene Name GNL3L
Enzyme 17 Protein Sequence >Guanine nucleotide-binding protein-like 3-like protein
MMKLRHKNKKPGKGSKGCKKPAKQNGKKAATKVAYSPQFFHSNDHASREAELKKKRVGEM
REKQQAAREQERHRRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKE
FHKVVEYSDVILEVLDSRDPLGCRCFQMEETVLRAEGNKKLVLVLNKIDLVPKEVVEKWL
EYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLG
EVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGVTKFMQEVYLDKFIRLLDAPGI
VPGPNSEVGTILRNCIHVQKLADPVTPVETILQRCNLEEISSYYGVSGFQTTEHFLTAVA
HRLGKKKKGGIYSQEQAAKAVLADWVSGKISFYTLPPSTHTLPTHLSAEIVKEMTEVFDI
EDTEQANEDTMECLATGESDELLGDMDPLEMEIKWLHSPMVKIADAMENKTTVYKIGDLT
GYCTNPNRHQMGWAKRNVDLHPRNNSMVDVCPVDRRPVLQRIMETDPLQQGQALASALKK
KKKIQKRADKLASKLSDSMMSALDLSGNADDSAGD
Enzyme 17 Number of Residues 575
Enzyme 17 Molecular Weight 64837.0
Enzyme 17 Theoretical pI 8.76
Enzyme 17 GO Classification
Function
Process
Component
Enzyme 17 General Function Involved in GTP binding
Enzyme 17 Specific Function Required for normal processing of ribosomal pre-rRNA. Required for cell proliferation. Binds GTP
Enzyme 17 Pathways Not Available
Enzyme 17 Reactions Not Available
Enzyme 17 Pfam Domain Function
Enzyme 17 Signals
  • None
Enzyme 17 Transmembrane Regions
  • None
Enzyme 17 Essentiality Not Available
Enzyme 17 GenBank ID Protein 74354000 Link Image
Enzyme 17 UniProtKB/Swiss-Prot ID Q3T0J9 Link Image
Enzyme 17 UniProtKB/Swiss-Prot Entry Name GNL3L_BOVIN Link Image
Enzyme 17 PDB ID Not Available
Enzyme 17 Cellular Location Not Available
Enzyme 17 Gene Sequence >1728 bp
ATGATGAAACTTAGACACAAAAATAAAAAGCCAGGTAAAGGTTCCAAAGGCTGCAAGAAG
CCTGCAAAGCAGAATGGGAAGAAAGCAGCCACCAAAGTGGCCTACTCTCCCCAGTTTTTC
CACTCCAATGATCACGCCAGTCGGGAGGCTGAGTTAAAGAAGAAGAGGGTTGGGGAAATG
AGGGAGAAGCAGCAGGCTGCCCGGGAGCAAGAGCGACACCGACGTAGGACCATTGAAAGC
TACTGCCAGGATGTCCTGAGACGCCAAGAGGAGTTTGAGCACAAGGAGGAAGTTTTGCAA
GAATTAAATATGTTTCCTCAACTGGATGATGAGGCTACAAGGAAGGCTTATTACAAGGAG
TTCCATAAGGTGGTGGAATACTCTGATGTGATTCTGGAAGTCCTGGATTCCAGGGACCCA
TTGGGCTGCCGCTGCTTCCAAATGGAGGAGACTGTCCTACGGGCAGAAGGGAACAAGAAG
CTGGTCCTGGTCTTGAACAAGATTGACCTGGTCCCTAAGGAGGTTGTGGAGAAGTGGCTA
GAATACCTTCGGAATGAGCTGCCAACTGTGGCTTTCAAGGCCAGTACCCAGCATCAGGTC
AAAAACCTGAATCGCTGCAGTGTGCCAGTGGATCAAGCCTCCGAGTCACTGCTGAAGAGC
AAAGCCTGCTTTGGAGCTGAAAACCTCATGAGGGTTCTGGGGAACTATTGCCGCCTTGGT
GAAGTGCGCACCCATATCCGAGTGGGCGTTGTGGGCCTTCCCAATGTTGGGAAGAGCAGC
CTGATCAATAGTCTGAAGCGCAGCCGTGCGTGTAGTGTGGGAGCCGTTCCTGGGGTCACC
AAGTTCATGCAGGAGGTCTACCTGGACAAGTTCATCAGGCTGCTGGATGCTCCGGGCATC
GTCCCAGGACCCAACTCAGAGGTGGGCACTATCCTGCGCAATTGCATTCACGTGCAGAAG
CTGGCGGACCCTGTGACCCCGGTGGAGACCATCCTGCAACGCTGCAACCTGGAGGAGATC
TCCAGCTATTATGGTGTCTCTGGGTTTCAGACCACTGAGCACTTTCTGACTGCAGTGGCC
CACCGCTTGGGGAAGAAGAAGAAGGGGGGCATTTATAGTCAGGAGCAGGCAGCCAAAGCT
GTGCTGGCTGACTGGGTGAGTGGGAAGATCAGCTTCTATACACTTCCACCCTCTACCCAC
ACTCTGCCTACCCATCTCAGTGCTGAGATCGTTAAGGAGATGACTGAGGTCTTTGACATT
GAGGATACCGAGCAAGCCAATGAAGACACCATGGAATGCTTGGCCACTGGAGAATCGGAT
GAGCTGTTGGGTGACATGGACCCGCTCGAAATGGAGATCAAGTGGCTCCATTCTCCGATG
GTGAAAATAGCAGATGCCATGGAAAATAAAACCACCGTGTATAAGATTGGAGATCTTACT
GGGTATTGCACCAATCCAAACCGTCATCAGATGGGATGGGCTAAGCGCAATGTGGACCTT
CACCCTAGGAACAATAGCATGGTGGATGTTTGCCCAGTGGACCGCCGCCCAGTGCTACAG
AGGATCATGGAGACAGACCCCCTGCAGCAGGGCCAGGCTCTGGCATCTGCCCTGAAGAAG
AAGAAGAAGATCCAGAAGCGTGCAGACAAACTTGCCAGCAAGCTGTCTGATTCCATGATG
TCCGCTCTTGACCTCTCTGGCAATGCTGATGACAGTGCTGGTGACTGA
Enzyme 17 GenBank Gene ID BC102363 Link Image
Enzyme 17 GeneCard ID GNL3L Link Image
Enzyme 17 GenAtlas ID Not Available
Enzyme 17 HGNC ID Not Available
Enzyme 17 Chromosome Location Not Available
Enzyme 17 Locus Xp11.22
Enzyme 17 SNPs SNPJam Report Link Image
Enzyme 17 General References Not Available
Enzyme 17 Metabolite References Not Available
Enzyme 18 [top]
Enzyme 18 ID 2199
Enzyme 18 Name Guanine nucleotide-binding protein G(T) subunit gamma-T1
Enzyme 18 Synonyms
  1. Transducin gamma chain
Enzyme 18 Gene Name GNGT1
Enzyme 18 Protein Sequence >Guanine nucleotide-binding protein G(T) subunit gamma-T1
MPVINIEDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEFRDYVEERSGEDPLVKGIPED
KNPFKELKGGCVIS
Enzyme 18 Number of Residues 74
Enzyme 18 Molecular Weight 8543.8
Enzyme 18 Theoretical pI 4.47
Enzyme 18 GO Classification
Function
Process
Component
Enzyme 18 General Function Involved in signal transducer activity
Enzyme 18 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
Enzyme 18 Pathways Not Available
Enzyme 18 Reactions Not Available
Enzyme 18 Pfam Domain Function
Enzyme 18 Signals
  • None
Enzyme 18 Transmembrane Regions
  • None
Enzyme 18 Essentiality Not Available
Enzyme 18 GenBank ID Protein 163789 Link Image
Enzyme 18 UniProtKB/Swiss-Prot ID P02698 Link Image
Enzyme 18 UniProtKB/Swiss-Prot Entry Name GBG1_BOVIN Link Image
Enzyme 18 PDB ID 1B9Y Link Image
Enzyme 18 PDB File Show
Enzyme 18 3D Structure
Enzyme 18 Cellular Location Not Available
Enzyme 18 Gene Sequence >225 bp
CAAACAGTTTGCTTAGCAGAAGATGCCAGTGATCAATATTGAGGACCTGACAGAAAAGGA
CAAATTGAAGATGGAAGTCGACCAGCTCAAGAAAGAAGTGACGCTGGAAAGAATGCTGGT
GTCCAAATGTTGTGAAGAATTCAGGGATTATGTTGAAGAAAGATCTGGGGAGGATCCATT
AGTAAAGGGTATCCCAGAGGACAAAAATCCCTTCAAGGAGCTCAA
Enzyme 18 GenBank Gene ID K03255 Link Image
Enzyme 18 GeneCard ID GNGT1 Link Image
Enzyme 18 GenAtlas ID Not Available
Enzyme 18 HGNC ID Not Available
Enzyme 18 Chromosome Location Chromosome:7
Enzyme 18 Locus 7q21.3
Enzyme 18 SNPs SNPJam Report Link Image
Enzyme 18 General References
  1. [PubMed Link Image]
Enzyme 18 Metabolite References Not Available
Enzyme 19 [top]
Enzyme 19 ID 2200
Enzyme 19 Name Guanine nucleotide-binding protein G(o) subunit alpha
Enzyme 19 Synonyms
  1. GTP-binding protein G39
Enzyme 19 Gene Name GNAO1
Enzyme 19 Protein Sequence >Guanine nucleotide-binding protein G(o) subunit alpha
MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG
FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF
SPELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV
KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET
TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGSNTYEDA
AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
Enzyme 19 Number of Residues 354
Enzyme 19 Molecular Weight 40066.2
Enzyme 19 Theoretical pI 5.19
Enzyme 19 GO Classification
Function
Process
Component
Enzyme 19 General Function Involved in GTP binding
Enzyme 19 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear
Enzyme 19 Pathways Not Available
Enzyme 19 Reactions Not Available
Enzyme 19 Pfam Domain Function
Enzyme 19 Signals
  • None
Enzyme 19 Transmembrane Regions
  • None
Enzyme 19 Essentiality Not Available
Enzyme 19 GenBank ID Protein 163068 Link Image
Enzyme 19 UniProtKB/Swiss-Prot ID P08239 Link Image
Enzyme 19 UniProtKB/Swiss-Prot Entry Name GNAO_BOVIN Link Image
Enzyme 19 PDB ID Not Available
Enzyme 19 Cellular Location Not Available
Enzyme 19 Gene Sequence >1065 bp
GGCAGGGAAGGGGCCACCATGGGATGGGATGTACTCTGAGCGCAGAGGAGCGAGCCGCCC
TCGAGCGGAGCAAGGCGATTGAGAAAAACCTCAAAGAGGATGGCATCAGCGCCGCCAAAG
ACGTGAAATTACTCCTGCTGGGGGCTGGAGAATCAGGAAAAAGCACCATTGTGAAGCAGA
TGAAGATCATCCACGAAGACGGCTTCTCTGGCGAAGACGTGAAGCAGTACAAGCCCGTGG
TCTACAGCAACACCATCCAGTCCCTGGCAGCCATCGTCCGGGCCATGGACACTCTGGGCA
TCGAGTACGGTGACAAGGAGCGAAAGGCCGACGCCAAGATGGTGTGTGACGTGGTGAGTC
GGATGGAAGACACGGAGCCCTTCTCTCCAGAGCTGCTCTCCGCCATGATGCGACTCTGGG
GCGACTCGGGGATCCAGGAGTGCTTCAACAGGTCCCGGGAATATCAGCTCAACGACTCTG
CCAAATACTACCTGGACAGCCTGGACCGGATCGGGGCCGCCGACTACCAGCCCACCGAGC
AGGACATCCTCCGAACCAGGGTCAAAACCACCGGCATCGTAGAAACCCACTTCACATTCA
AGAACCTCCACTTCAGGCTGTTCGACGTCGGGGGCCAGCGGTCTGAGCGCAAGAAGTGGA
TTCACTGCTTCGAGGACGTCACGGCCATCATCTTCTGTGTCGCGCTCAGCGGCTATGACC
AGGTGCTCCACGAAGACGAGACCACGAACCGCATGCACGAGTCTCTCATGCTCTTCGACT
CCATCTGTAACAACAAGTTCTTCATCGATATCTCCATCATTCTCTTCCTCAACAAGAAAG
ATCTCTTTGGGGAGAAGATCAAGAAGTCACCTCTGACCATCTGCTTTCCCGAGTACACAG
GCTCCAACACCTATGAAGACGCCGCCGCCTACATCCAAGCACAATTTGAAAGCAAAAACC
GCTCACCCAACAAAGAAATTTATTGTCACATGACTTGTGCCACAGACACGAATAATATCC
AGGTGGTATTCGACGCTGTCACCGACATCATCATTGCCAACAACC
Enzyme 19 GenBank Gene ID M16116 Link Image
Enzyme 19 GeneCard ID GNAO1 Link Image
Enzyme 19 GenAtlas ID Not Available
Enzyme 19 HGNC ID Not Available
Enzyme 19 Chromosome Location Chromosome:1
Enzyme 19 Locus 16q13
Enzyme 19 SNPs SNPJam Report Link Image
Enzyme 19 General References
  1. [PubMed Link Image]
Enzyme 19 Metabolite References Not Available
Enzyme 20 [top]
Enzyme 20 ID 2201
Enzyme 20 Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
Enzyme 20 Synonyms
  1. G gamma-C
  2. G-gamma-8
Enzyme 20 Gene Name GNGT2
Enzyme 20 Protein Sequence >Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
MAQELSEKELLKMEVEQLKKEVKNPRALISKTGKEIKDYVEAEAGNDPLLKGIPEDKNPF
KEKGGCIIS
Enzyme 20 Number of Residues 69
Enzyme 20 Molecular Weight 7727.9
Enzyme 20 Theoretical pI 5.19
Enzyme 20 GO Classification
Function
Process
Component
Enzyme 20 General Function Involved in signal transducer activity
Enzyme 20 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
Enzyme 20 Pathways Not Available
Enzyme 20 Reactions Not Available
Enzyme 20 Pfam Domain Function
Enzyme 20 Signals
  • None
Enzyme 20 Transmembrane Regions
  • None
Enzyme 20 Essentiality Not Available
Enzyme 20 GenBank ID Protein 885892 Link Image
Enzyme 20 UniProtKB/Swiss-Prot ID P50154 Link Image
Enzyme 20 UniProtKB/Swiss-Prot Entry Name GBGT2_BOVIN Link Image
Enzyme 20 PDB ID Not Available
Enzyme 20 Cellular Location Not Available
Enzyme 20 Gene Sequence >210 bp
ATGGCCCAAGAGCTCAGCGAGAAGGAACTCTTAAAGATGGAGGTAGAGCAGCTGAAGAAG
GAAGTGAAGAACCCAAGAGCTCTGATTTCCAAAACAGGAAAGGAAATCAAGGATTATGTG
GAGGCTGAAGCAGGAAACGACCCTCTTCTTAAAGGCATCCCTGAGGACAAGAATCCCTTC
AAGGAAAAAGGCGGTTGTATAATAAGCTGA
Enzyme 20 GenBank Gene ID U20085 Link Image
Enzyme 20 GeneCard ID GNGT2 Link Image
Enzyme 20 GenAtlas ID Not Available
Enzyme 20 HGNC ID Not Available
Enzyme 20 Chromosome Location Chromosome:1
Enzyme 20 Locus 17q21
Enzyme 20 SNPs SNPJam Report Link Image
Enzyme 20 General References
  1. [PubMed Link Image]
Enzyme 20 Metabolite References Not Available
Enzyme 21 [top]
Enzyme 21 ID 2202
Enzyme 21 Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Enzyme 21 Synonyms Not Available
Enzyme 21 Gene Name GNG5
Enzyme 21 Protein Sequence >Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
MSGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFR
PQKVCSFL
Enzyme 21 Number of Residues 68
Enzyme 21 Molecular Weight 7318.4
Enzyme 21 Theoretical pI 10.62
Enzyme 21 GO Classification
Function
Process
Component
Enzyme 21 General Function Involved in signal transducer activity
Enzyme 21 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
Enzyme 21 Pathways Not Available
Enzyme 21 Reactions Not Available
Enzyme 21 Pfam Domain Function
Enzyme 21 Signals
  • None
Enzyme 21 Transmembrane Regions
  • None
Enzyme 21 Essentiality Not Available
Enzyme 21 GenBank ID Protein 163076 Link Image
Enzyme 21 UniProtKB/Swiss-Prot ID P63217 Link Image
Enzyme 21 UniProtKB/Swiss-Prot Entry Name GBG5_BOVIN Link Image
Enzyme 21 PDB ID Not Available
Enzyme 21 Cellular Location Not Available
Enzyme 21 Gene Sequence >207 bp
ATGTCTGGTTCATCCAGCGTCGCGGCTATGAAAAAAGTGGTTCAACAGCTCCGGCTGGAG
GCCGGGCTCAATCGGGTGAAGGTTTCCCAGGCAGCTGCAGATTTGAAACAGTTCTGTCTG
CAGAATGCTCAACATGACCCTCTGCTGACTGGAGTATCTTCAAGTACAAATCCCTTCAGG
CCCCAGAAAGTCTGTTCCTTTTTGTAG
Enzyme 21 GenBank Gene ID M95779 Link Image
Enzyme 21 GeneCard ID GNG5 Link Image
Enzyme 21 GenAtlas ID Not Available
Enzyme 21 HGNC ID Not Available
Enzyme 21 Chromosome Location Chromosome:1
Enzyme 21 Locus 1p22
Enzyme 21 SNPs SNPJam Report Link Image
Enzyme 21 General References
  1. [PubMed Link Image]
Enzyme 21 Metabolite References Not Available
Enzyme 22 [top]
Enzyme 22 ID 2203
Enzyme 22 Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Enzyme 22 Synonyms
  1. G gamma-I
Enzyme 22 Gene Name GNG2
Enzyme 22 Protein Sequence >Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP
FREKKFFCAIL
Enzyme 22 Number of Residues 71
Enzyme 22 Molecular Weight 7850.0
Enzyme 22 Theoretical pI 8.22
Enzyme 22 GO Classification
Function
Process
Component
Enzyme 22 General Function Involved in signal transducer activity
Enzyme 22 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
Enzyme 22 Pathways Not Available
Enzyme 22 Reactions Not Available
Enzyme 22 Pfam Domain Function
Enzyme 22 Signals
  • None
Enzyme 22 Transmembrane Regions
  • None
Enzyme 22 Essentiality Not Available
Enzyme 22 GenBank ID Protein 163086 Link Image
Enzyme 22 UniProtKB/Swiss-Prot ID P63212 Link Image
Enzyme 22 UniProtKB/Swiss-Prot Entry Name GBG2_BOVIN Link Image
Enzyme 22 PDB ID 1GP2 Link Image
Enzyme 22 PDB File Show
Enzyme 22 3D Structure
Enzyme 22 Cellular Location Not Available
Enzyme 22 Gene Sequence >216 bp
ATGGCCAGCAACAACACCGCCAGCATAGCACAAGCCAGGAAACTGGTAGAACAGCTGAAG
ATGGAAGCCAACATCGATAGGATAAAGGTGTCCAAGGCAGCTGCAGATTTGATGGCCTAC
TGTGAAGCGCATGCCAAGGAAGATCCCCTCCTGACACCTGTTCCGGCTTCAGAAAACCCA
TTTAGGGAGAAGAAGTTTTTCTGTGCTATCCTTTAA
Enzyme 22 GenBank Gene ID J05071 Link Image
Enzyme 22 GeneCard ID GNG2 Link Image
Enzyme 22 GenAtlas ID Not Available
Enzyme 22 HGNC ID Not Available
Enzyme 22 Chromosome Location Chromosome:1
Enzyme 22 Locus 14q21
Enzyme 22 SNPs SNPJam Report Link Image
Enzyme 22 General References
  1. [PubMed Link Image]
Enzyme 22 Metabolite References Not Available
Enzyme 23 [top]
Enzyme 23 ID 2204
Enzyme 23 Name Target of rapamycin complex subunit LST8
Enzyme 23 Synonyms
  1. TORC subunit LST8
  2. Mammalian lethal with SEC13 protein 8
  3. mLST8
  4. G protein beta subunit-like
  5. Protein GbetaL
Enzyme 23 Gene Name MLST8
Enzyme 23 Protein Sequence >Target of rapamycin complex subunit LST8
MNTSPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEITPDRTMIAAA
GYQHIRMYDLNSNNPNPIISYDGVNKNVASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQ
CQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDP
DASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSA
DQTCKIWRTSNFSLMTELSIKSSNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVE
TGEIKREYGGHQKAVVCLAFNDSVLG
Enzyme 23 Number of Residues 326
Enzyme 23 Molecular Weight 35919.9
Enzyme 23 Theoretical pI 5.72
Enzyme 23 GO Classification
Function
Process
Component
Enzyme 23 General Function Not Available
Enzyme 23 Specific Function Subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Amino-acid-signaling to mTORC1 is mediated by Rag GTPases, which cause amino-acid-induced relocalization of mTOR within the endomembrane system. Growth factor-stimulated mTORC1 activation involves AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, LST8 interacts directly with FRAP1 and enhances its kinase activity. In nutrient- poor conditions, stabilizes the FRAP1-RPTOR interaction and favors RPTOR-mediated inhibition of FRAP1 activity. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum- induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'
Enzyme 23 Pathways Not Available
Enzyme 23 Reactions Not Available
Enzyme 23 Pfam Domain Function
Enzyme 23 Signals
  • None
Enzyme 23 Transmembrane Regions
  • None
Enzyme 23 Essentiality Not Available
Enzyme 23 GenBank ID Protein 61553455 Link Image
Enzyme 23 UniProtKB/Swiss-Prot ID Q17QU5 Link Image
Enzyme 23 UniProtKB/Swiss-Prot Entry Name LST8_BOVIN Link Image
Enzyme 23 PDB ID Not Available
Enzyme 23 Cellular Location Not Available
Enzyme 23 Gene Sequence >1059 bp
ATGAATACGTCTCCAGGCACAGTGGGCAGTGACCCCGTCATCTTGGCCACTGCAGGCTAT
GACCACACGGTGCGGTTCTGGCAGGCCCACAGCGGGATCTGTACGCGAACTGTGCAGCAC
CAGGACTCCCAGGTGAACGCGCTGGAGATCACACCCGACCGCACCATGATTGCAGCTGCA
GGTTACCAGCACATTCGCATGTATGATCTCAACTCCAATAACCCCAACCCCATCATCAGC
TACGACGGGGTCAACAAGAACGTCGCGTCGGTGGGCTTCCACGAGGACGGGCGCTGGATG
TACACGGGCGGGGAGGACTGCACAGCCCGGATCTGGGACCTCAGGTCCCGGAACCTGCAG
TGTCAGCGAATCTTCCAGGTGAATGCACCCATTAACTGCGTGTGCCTGCACCCCAACCAG
GCGGAGCTCATCGTGGGTGACCAGAGCGGCGCCATCCACATCTGGGACTTGAAAACTGAC
CACAATGAGCAGCTGATCCCGGAGCCGGAAGTCTCCATCACATCCGCCCACATCGACCCA
GATGCCAGCTACATGGCTGCCGTCAATAGTACTGGGAACTGCTATGTCTGGAACCTGACT
GGAGGCATTGGCGACGAGGTGACACAGCTCATCCCCAAGACCAAGATCCCGGCGCACACC
CGCTATGCCCTGCAGTGCCGCTTCAGCCCCGACTCCACGCTCCTCGCCACCTGCTCGGCC
GACCAGACGTGCAAGATCTGGAGGACGTCCAACTTCTCCCTGATGACAGAGCTGAGCATC
AAGAGCAGTAATCCCGGAGAGTCATCTCGGGGCTGGATGTGGGGCTGCGCCTTCTCAGGA
GACTCGCAATACATCGTCACCGCTTCCTCTGACAACCTGGCCCGGCTCTGGTGTGTGGAG
ACAGGCGAGATCAAGAGAGAGTATGGCGGCCACCAGAAAGCTGTTGTGTGCTTGGCCTTC
ACGACAGCGTGCTGGGCTAGCCTCGTTCCTGGGCACTGCAGGCAGCCGTCCAGGTGGCAC
CAGCCGGGTGTGTCTGTCCAGCTGCCCAGGTCAGCGTGA
Enzyme 23 GenBank Gene ID BT021562 Link Image
Enzyme 23 GeneCard ID MLST8 Link Image
Enzyme 23 GenAtlas ID Not Available
Enzyme 23 HGNC ID Not Available
Enzyme 23 Chromosome Location Not Available
Enzyme 23 Locus Not Available
Enzyme 23 SNPs SNPJam Report Link Image
Enzyme 23 General References
  1. [PubMed Link Image]
Enzyme 23 Metabolite References Not Available
Enzyme 24 [top]
Enzyme 24 ID 2205
Enzyme 24 Name Guanine nucleotide-binding protein Gq
Enzyme 24 Synonyms Not Available
Enzyme 24 Gene Name Not Available
Enzyme 24 Protein Sequence >Guanine nucleotide-binding protein Gq
ENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFSTSVILFLNKTDILEE
KIPTSHLATYFPSFRGPKQDAEAAKKFILDMYTRMYAGCVDG
Enzyme 24 Number of Residues 102
Enzyme 24 Molecular Weight 11661.2
Enzyme 24 Theoretical pI 4.36
Enzyme 24 GO Classification
Function
Process
Component
Enzyme 24 General Function Involved in guanyl nucleotide binding
Enzyme 24 Specific Function Not Available
Enzyme 24 Pathways Not Available
Enzyme 24 Reactions Not Available
Enzyme 24 Pfam Domain Function
Enzyme 24 Signals
  • None
Enzyme 24 Transmembrane Regions
  • None
Enzyme 24 Essentiality Not Available
Enzyme 24 GenBank ID Protein 68161556 Link Image
Enzyme 24 UniProtKB/Swiss-Prot ID Q4JM29 Link Image
Enzyme 24 UniProtKB/Swiss-Prot Entry Name Q4JM29_BOVIN Link Image
Enzyme 24 PDB ID Not Available
Enzyme 24 Cellular Location Not Available
Enzyme 24 Gene Sequence Not Available
Enzyme 24 GenBank Gene ID DQ072112 Link Image
Enzyme 24 GeneCard ID Not Available
Enzyme 24 GenAtlas ID Not Available
Enzyme 24 HGNC ID Not Available
Enzyme 24 Chromosome Location Not Available
Enzyme 24 Locus Not Available
Enzyme 24 SNPs SNPJam Report Link Image
Enzyme 24 General References Not Available
Enzyme 24 Metabolite References Not Available
Enzyme 25 [top]
Enzyme 25 ID 2206
Enzyme 25 Name Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Enzyme 25 Synonyms
  1. Transducin beta chain 1
Enzyme 25 Gene Name GNB1
Enzyme 25 Protein Sequence >Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF
TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL
KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
Enzyme 25 Number of Residues 340
Enzyme 25 Molecular Weight 37376.6
Enzyme 25 Theoretical pI 5.85
Enzyme 25 GO Classification
Function
Process
Component
Enzyme 25 General Function Involved in signal transducer activity
Enzyme 25 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
Enzyme 25 Pathways Not Available
Enzyme 25 Reactions Not Available
Enzyme 25 Pfam Domain Function
Enzyme 25 Signals
  • None
Enzyme 25 Transmembrane Regions
  • None
Enzyme 25 Essentiality Not Available
Enzyme 25 GenBank ID Protein 814 Link Image
Enzyme 25 UniProtKB/Swiss-Prot ID P62871 Link Image
Enzyme 25 UniProtKB/Swiss-Prot Entry Name GBB1_BOVIN Link Image
Enzyme 25 PDB ID 1OMW Link Image
Enzyme 25 PDB File Show
Enzyme 25 3D Structure
Enzyme 25 Cellular Location Not Available
Enzyme 25 Gene Sequence >1023 bp
ATGAGTGAACTTGACCAGTTACGGCAGGAGGCCGAACAGCTTAAAAACCAAATTAGAGAT
GCTCGGAAGGCGTGTGCAGATGCGACTCTCTCTCAGATCACAAACAACATCGACCCTGTG
GGAAGAATCCAGATGCGCACCAGGAGGACGCTGAGGGGACACTTGGCCAAGATCTATGCC
ATGCACTGGGGCACCGACTCCAGGCTTCTACTCAGTGCCTCGCAGGATGGTAAACTTATT
ATCTGGGACAGCTACACCACAAACAAGGTCCATGCCATCCCTCTGCGCTCCTCGTGGGTC
ATGACGTGCGCTTATGCCCCTTCTGGGAACTACGTGGCCTGTGGAGGCCTGGATAACATC
TGCTCCATTTACAATCTGAAAACTCGTGAAGGGAATGTACGTGTGAGTCGTGAGCTGGCT
GGACACACAGGTTACCTGTCCTGCTGCCGTTTTCTGGATGACAATCAGATTGTTACCAGC
TCTGGAGACACCACCTGTGCCCTGTGGGACATCGAGACTGGCCAGCAGACGACCACATTC
ACTGGACACACCGGAGACGTCATGAGCCTTTCACTCGCTCCGGACACCAGACTGTTTGTC
TCTGGTGCTTGTGACGCTTCAGCCAAACTCTGGGACGTGCGAGAAGGGATGTGCCGGCAA
ACCTTCACCGGCCATGAGTCCGATATCAATGCCATCTGTTTCTTCCCGAACGGCAATGCA
TTTGCCACTGGCTCAGACGATGCCACCTGCCGGCTGTTCGACCTCCGTGCGGACCAGGAG
CTCATGACCTACTCCCATGACAACATCATCTGCGGGATCACCTCCGTCTCCTTCTCCAAG
AGCGGGCGCCTCCTTCTCGCAGGGTACGACGACTTCAACTGCAACGTCTGGGACGCCCTC
AAGGCCGACAGGGCAGGGGTCTTGGCCGGGCATGACAACCGCGTGAGCTGCCTGGGGGTA
ACTGATGACGGGATGGCCGTGGCGACGGGATCCTGGGACAGCTTCCTCAAAATCTGGAAC
TAA
Enzyme 25 GenBank Gene ID X03073 Link Image
Enzyme 25 GeneCard ID GNB1 Link Image
Enzyme 25 GenAtlas ID Not Available
Enzyme 25 HGNC ID Not Available
Enzyme 25 Chromosome Location Chromosome:1
Enzyme 25 Locus 1p36.33
Enzyme 25 SNPs SNPJam Report Link Image
Enzyme 25 General References
  1. [PubMed Link Image]
Enzyme 25 Metabolite References Not Available
Enzyme 26 [top]
Enzyme 26 ID 2207
Enzyme 26 Name Guanine nucleotide binding protein-like 2 (Nucleolar)
Enzyme 26 Synonyms Not Available
Enzyme 26 Gene Name GNL2
Enzyme 26 Protein Sequence >Guanine nucleotide binding protein-like 2 (Nucleolar)
MVKPKYKGRSTINPSNASTNPDRVQGAGGHNMRDRATIRRLNMYRQKERRNSRGKVIKPL
QYQSTVASGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMDTVLKDPYKVVMKQSKLPMSL
LHDRIRPHNAKVHILDTESFETTFGPKAQRKRPNLFASDMQSLIENAETSTESYDQGKDR
DLVAEDTGVRNEAQEEIFKKGQSKRIWGELYKVIDSSDVVVQVLDARDPVGTRSPHIETY
LKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ
FGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLI
DCPGVVYPSEDSETDIVLKGVVQVEKIKTPEDHIGAVLERAKPEYISKTYKINSWENAED
FLEKLAFRTGKLLKGGEPDLRTVGKMVLNDWQRGRIPFFVKPPNAEPPAAPELPSSSSLE
VAAETTQNNPGEKVTETVGEESESILEKEKEEPRHCGIDSEMQQILARVRQNFGKINVAP
QFSGDDLVPLEMSDIDDELESLSAENEEEEEQEYPGDDEDESYAESQEEHAGRTTKAVIQ
ALDEKIAKYQRFLNKAKAKKFSAIRISKGLSEMVFAKSEGRKKGKAEEDVDDTAPPKKGK
KRKAQREEEQPDKTRRTLTSKERRREARQQRSRKVGVRYYETHNVKNRNRNKKKTTDSEG
QKHRHKKAKHKQ
Enzyme 26 Number of Residues 732
Enzyme 26 Molecular Weight 83482.1
Enzyme 26 Theoretical pI 9.98
Enzyme 26 GO Classification
Function
Process
Component
Enzyme 26 General Function Involved in GTP binding
Enzyme 26 Specific Function Not Available
Enzyme 26 Pathways Not Available
Enzyme 26 Reactions Not Available
Enzyme 26 Pfam Domain Function
Enzyme 26 Signals
  • None
Enzyme 26 Transmembrane Regions
  • None
Enzyme 26 Essentiality Not Available
Enzyme 26 GenBank ID Protein 95769512 Link Image
Enzyme 26 UniProtKB/Swiss-Prot ID Q1JP69 Link Image
Enzyme 26 UniProtKB/Swiss-Prot Entry Name Q1JP69_BOVIN Link Image
Enzyme 26 PDB ID Not Available
Enzyme 26 Cellular Location Not Available
Enzyme 26 Gene Sequence >2199 bp
ATGGTGAAGCCCAAGTACAAAGGACGGAGCACTATCAACCCCTCTAATGCCAGCACAAAT
CCCGATCGAGTGCAGGGAGCAGGAGGTCACAACATGAGGGACCGGGCCACAATTCGACGC
CTGAATATGTACAGACAGAAGGAGCGCAGGAACAGCCGTGGTAAAGTGATTAAGCCTCTG
CAGTATCAGTCAACGGTGGCTTCTGGCACAGTGGCAAGAGTGGAGCCAAACATTAAGTGG
TTTGGAAATACACGTGTGATTAAGCAGTCATCATTACAAAAATTTCAAGAGGAAATGGAC
ACAGTCTTGAAGGATCCATACAAAGTTGTCATGAAGCAAAGCAAGTTACCCATGTCTCTT
CTCCATGATCGAATCCGGCCTCATAATGCAAAGGTGCACATCCTTGATACTGAAAGCTTC
GAAACAACATTTGGCCCCAAAGCGCAGAGGAAGCGGCCAAATTTATTTGCAAGTGATATG
CAGTCACTTATAGAAAATGCAGAAACATCCACTGAGAGCTATGACCAGGGCAAGGATCGT
GACTTGGTAGCTGAAGACACTGGTGTGAGAAATGAAGCCCAAGAAGAGATATTTAAAAAG
GGACAGTCTAAAAGAATATGGGGTGAGCTCTACAAGGTGATAGATTCATCAGATGTTGTG
GTTCAAGTTCTTGATGCTAGAGATCCAGTGGGTACACGTTCCCCTCACATTGAGACTTAC
CTGAAAAAAGAGAAACCCTGGAAACATCTCATTTTTGTTCTTAACAAATGTGACCTTGTT
CCAACCTGGGCAACGAAACGATGGGTTGCCGTCCTCTCCCAGGATTACCCGACGCTTGCT
TTCCACGCGAGTCTTACTAACCCCTTCGGCAAAGGAGCGTTTATTCAGCTTCTGCGGCAG
TTTGGAAAGTTGCACACTGACAAGAAGCAGATCAGCGTGGGGTTCATTGGCTATCCAAAC
GTTGGCAAGAGCTCTGTGATAAACACACTGCGCTCCAAGAAGGTCTGCAACGTGGCCCCC
ATCGCAGGTGAAACAAAGGTCTGGCAGTACATTACCTTGATGCGTCGGATCTTCCTCATC
GACTGTCCGGGTGTGGTTTACCCCTCCGAGGACTCAGAGACGGACATTGTGCTGAAGGGA
GTCGTTCAAGTTGAAAAAATTAAGACTCCTGAAGACCACATTGGTGCTGTACTTGAACGA
GCAAAACCAGAGTATATCAGCAAGACGTACAAGATTAATTCTTGGGAGAACGCTGAGGAC
TTTCTGGAGAAGCTAGCTTTCCGGACAGGGAAGTTATTAAAGGGTGGAGAGCCCGACCTG
CGGACTGTGGGGAAGATGGTCCTCAATGACTGGCAGAGGGGCCGGATTCCTTTCTTTGTC
AAGCCGCCCAATGCAGAACCCCCAGCAGCCCCCGAGCTTCCATCCTCCTCATCTTTGGAA
GTTGCCGCAGAAACAACCCAGAACAACCCAGGAGAGAAAGTCACGGAAACAGTAGGTGAG
GAGTCGGAATCCATCCTCGAGAAGGAAAAAGAGGAGCCCCGGCACTGTGGCATCGATTCA
GAAATGCAGCAGATTCTGGCGCGGGTCCGGCAGAACTTTGGCAAGATCAACGTTGCACCT
CAGTTTTCTGGGGATGACCTGGTTCCTCTGGAGATGTCCGATATCGATGACGAGCTGGAG
AGCCTTTCTGCGGAGAATGAGGAGGAGGAGGAACAGGAGTACCCAGGAGACGATGAGGAC
GAGTCTTATGCAGAGTCCCAGGAGGAACATGCGGGACGCACCACTAAGGCCGTTATTCAA
GCCCTGGATGAAAAGATCGCCAAGTACCAGAGGTTTTTAAACAAAGCCAAAGCTAAGAAG
TTTTCAGCAATCAGGATATCCAAGGGACTGAGTGAAATGGTTTTTGCAAAATCCGAAGGA
CGAAAAAAAGGAAAAGCTGAAGAAGATGTAGATGATACAGCACCTCCCAAAAAGGGAAAG
AAGAGGAAGGCCCAGAGGGAAGAGGAGCAGCCAGACAAAACCCGCAGGACGCTTACGTCT
AAGGAGAGGAGGCGAGAAGCACGGCAGCAGCGATCTAGAAAAGTCGGCGTACGCTACTAT
GAAACACACAATGTGAAGAATAGGAACAGGAACAAAAAGAAGACCACCGACTCAGAAGGG
CAGAAACACAGACACAAGAAAGCCAAACATAAGCAGTAA
Enzyme 26 GenBank Gene ID BT025485 Link Image
Enzyme 26 GeneCard ID GNL2 Link Image
Enzyme 26 GenAtlas ID Not Available
Enzyme 26 HGNC ID Not Available
Enzyme 26 Chromosome Location Chromosome:1
Enzyme 26 Locus 1p34.3
Enzyme 26 SNPs SNPJam Report Link Image
Enzyme 26 General References
  1. [PubMed Link Image]
Enzyme 26 Metabolite References Not Available
Enzyme 27 [top]
Enzyme 27 ID 2208
Enzyme 27 Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Enzyme 27 Synonyms
  1. Gamma-II
Enzyme 27 Gene Name GNG7
Enzyme 27 Protein Sequence >Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
MSATNNIAQARKLVEQLRIEAGIERIKVSKASSELMSYCEQHARNDPLLVGVPASENPFK
DKKPCIIL
Enzyme 27 Number of Residues 68
Enzyme 27 Molecular Weight 7551.7
Enzyme 27 Theoretical pI 8.77
Enzyme 27 GO Classification
Function
Process
Component
Enzyme 27 General Function Involved in signal transducer activity
Enzyme 27 Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum
Enzyme 27 Pathways Not Available
Enzyme 27 Reactions Not Available
Enzyme 27 Pfam Domain Function
Enzyme 27 Signals
  • None
Enzyme 27 Transmembrane Regions
  • None
Enzyme 27 Essentiality Not Available
Enzyme 27 GenBank ID Protein Not Available
Enzyme 27 UniProtKB/Swiss-Prot ID P30671 Link Image
Enzyme 27 UniProtKB/Swiss-Prot Entry Name GBG7_BOVIN Link Image
Enzyme 27 PDB ID Not Available
Enzyme 27 Cellular Location Not Available
Enzyme 27 Gene Sequence Not Available
Enzyme 27 GenBank Gene ID M99393 Link Image
Enzyme 27 GeneCard ID GNG7 Link Image
Enzyme 27 GenAtlas ID Not Available
Enzyme 27 HGNC ID Not Available
Enzyme 27 Chromosome Location Chromosome:1
Enzyme 27 Locus 19p13.3
Enzyme 27 SNPs SNPJam Report Link Image
Enzyme 27 General References
  1. [PubMed Link Image]
Enzyme 27 Metabolite References Not Available