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Bovine Metabolome Database



Showing metabocard for Fructose 6-phosphate (BMDB00124)

Legend: metabolite field enzyme field

Version 1.0
Creation Date 2005-11-16 15:48:42
Update Date 2009-05-05 20:57:42
Accession Number BMDB00124
Common Name Fructose 6-phosphate
Description An important intermediate in the Carbohydrates pathway. The interconversion of glucose-6-phosphate and fructose-6-phosphate, the second step of the Embden-Meyerhof glycolytic pathway, is catalyzed by the enzyme phosphoglucose isomerase (PGI). In gluconeogenesis, fructose-6-phosphate is the immediate precursor of glucose-6-phosphate (wikipedia)
Synonyms
  1. D-Fructose 6-phosphate
  2. D-Fructose 6-phosphorate
  3. D-Fructose 6-phosphoric acid
  4. D-fructose-6-P
  5. D-fructose-6-phosphate
  6. FPC
  7. Fructose 6-phosphate
  8. Fructose 6-phosphic acid
  9. Fructose-6-phosphate
  10. Neuberg ester
  11. fru-6-P
  12. fructose-6-P
  13. fructose-6P
Chemical IUPAC Name [(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxo-hexoxy]phosphonic acid
Chemical Formula C6H13O9P
Chemical Structure Structure
Chemical Taxonomy
Kingdom
  • Organic
Super Class
  • Carbohydrates and Carbohydrate conjugates
Class
  • Sugar Phosphates
Sub Class
  • Monosaccharide phosphates
Family
  • Mammalian_Metabolite
Species
  • ketone; primary alcohol; secondary alcohol; 1,2-diol; phosphoric acid ester
Biofunction
  • Component of Aminosugars metabolism; Component of Fructose and mannose metabolism; Component of Galactose metabolism; Component of Glutamate metabolism; Component of Starch and sucrose metabolism
Application
Source
  • Endogenous
Average Molecular Weight 260.136
Monoisotopic Molecular Weight 260.029724
Isomeric SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
Canonical SMILES OCC(=O)C(O)C(O)C(O)COP(O)(O)=O
KEGG Compound ID C00085; C05345 Link Image
BioCyc ID FRUCTOSE-6P Link Image
BiGG ID 33795 Link Image
Wikipedia Link Fructose 6-phosphate Link Image
METLIN ID 5159 Link Image
PubChem Compound 69507 Link Image
PubChem Substance 8192994 Link Image
ChEBI ID 15946 Link Image
CAS Registry Number 643-13-0
InChI Identifier InChI=1/C6H13O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h4-7,9-11H,1-2H2,(H2,12,13,14)/t4-,5-,6-/m1/s1
Synthesis Reference Not Available
Melting Point (Experimental) Not Available
Experimental Water Solubility 911 mg/mL [HMP experimental] Source: PhysProp
Predicted Water Solubility 1000.0 mg/mL [MEYLAN,WM et al. (1996)]; 23.199999 mg/mL [Predicted by ALOGPS] Calculated using ALOGPS
Physiological Charge -2
State Solid
Experimental LogP/Hydrophobicity Not Available Source: PhysProp
Predicted LogP/Hydrophobicity -1.86 [Predicted by ALOGPS]; -5.1 [Predicted by PubChem via XLOGP]; -2.14 [MEYLAN,WM & HOWARD,PH (1995)] Calculated using ALOGPS
Material Safety Data Sheet (MSDS)
MOL File Show
SDF File Show
PDB File Show
2D Structure
3D Structure
Experimental PDB ID 1CNQ Link Image
Experimental PDB File Show
Experimental PDB Structure
Experimental 1H NMR Spectrum Download Spectrum
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Experimental 13C NMR Spectrum Not Available
Experimental 13C HSQC Spectrum Download Spectrum
Download FID (Bruker)
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Predicted 1H NMR Spectrum Show Image
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Predicted 13C NMR Spectrum Show Image
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Mass Spectrum
Low Energy
Download File
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Medium Energy
Download File
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High Energy
Download File
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Simplified TOCSY Spectrum Show Image
Show Peaklist
BMRB Spectrum Show Image
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Cellular Location
  • Cytoplasm (Predicted from LogP)
Biofluid Location Not Available
Tissue Location
Tissue References
Intestine
Concentrations (Normal) Not Available
Concentrations (Abnormal) Not Available
Pathway Names
  • Aminosugars metabolism
  • Fructose and Mannose Metabolism
  • Glycolysis
  • Pentose Pathway
  • Starch and Sucrose Metabolism
HMDB Pathways
Name Aminosugars metabolism
Image Show Link Image
Name Fructose and Mannose Metabolism
Image Show Link Image
Name Glycolysis
Image Show Link Image
Name Pentose Pathway
Image Show Link Image
Name Starch and Sucrose Metabolism
Image Show Link Image
KEGG Pathways
Name Aminosugars metabolism
Image Show Link Image
Name Fructose and Mannose Metabolism
Image Show Link Image
Name Glycolysis
Image Show Link Image
Name Pentose Pathway
Image Show Link Image
Name Starch and Sucrose Metabolism
Image Show Link Image
SimCell Pathways
Name Aminosugars metabolism
Image Show Link Image
Graph
SBML
Name Fructose and Mannose Metabolism
Image Show Link Image
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SBML Download (XML) Link Image
Name Glycolysis
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SBML Download (XML) Link Image
Name Pentose Pathway
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SBML Download (XML) Link Image
Name Starch and Sucrose Metabolism
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Graph
SBML
General References
  1. Wikipedia Link Image
Metabolic Enzymes
  1. Transaldolase
  2. Transaldolase
  3. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
  4. Fructose-1,6-bisphosphatase isozyme 2
  5. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
  6. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  7. Fructose-1,6-bisphosphatase 1
  8. 6-phosphofructokinase, liver type
  9. 6-phosphofructokinase, muscle type
  10. Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2
  11. Probable fructose-2,6-bisphosphatase TIGAR
Enzyme 1 [top]
Enzyme 1 ID 103
Enzyme 1 Name Transaldolase
Enzyme 1 Synonyms Not Available
Enzyme 1 Gene Name TALDO1
Enzyme 1 Protein Sequence >Transaldolase
MSGSPVKRQRMENALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPTYQE
LVEEAIAYGRKLGGSQEEQITNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVA
RARRLIELYKEAGISKERILIKLSSTWEGIQAGKELEEHHGIRCNMTLLFSFAQAVACAE
AGVTLISPFVGRILDWHVANTDKKSYETQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRN
TGEIKALAGCDFLTISPQLLGELLKDHSKLTPVLSAKAAQASDLEKIQLDEKAFRWLHNE
DRMAVEKLSDGIRRFAADAVKLERMLRERMFSAENGK
Enzyme 1 Number of Residues 337
Enzyme 1 Molecular Weight 37684.9
Enzyme 1 Theoretical pI 7.59
Enzyme 1 GO Classification
Function
Process
Component
Enzyme 1 General Function Carbohydrate transport and metabolism
Enzyme 1 Specific Function Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Enzyme 1 Pathways
  • Carbohydrate degradation
  • pentose phosphate pathway
  • D- glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D- ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage):step 2/3
Enzyme 1 Reactions Not Available
Enzyme 1 Pfam Domain Function
Enzyme 1 Signals
  • None
Enzyme 1 Transmembrane Regions
  • None
Enzyme 1 Essentiality Not Available
Enzyme 1 GenBank ID Protein 83638723 Link Image
Enzyme 1 UniProtKB/Swiss-Prot ID Q2TBL6 Link Image
Enzyme 1 UniProtKB/Swiss-Prot Entry Name TALDO_BOVIN Link Image
Enzyme 1 PDB ID 1F05 Link Image
Enzyme 1 PDB File Show
Enzyme 1 3D Structure
Enzyme 1 Cellular Location Not Available
Enzyme 1 Gene Sequence >1014 bp
ATGTCGGGCTCCCCGGTGAAGCGGCAGAGGATGGAGAACGCGCTGGACCAGCTCAAGCAG
TTCACCACCGTGGTGGCCGACACGGGCGACTTCCACGCCATCGACGAGTACAAGCCCCAG
GATGCCACCACCAACCCGTCCCTGATCCTGGCTGCGGCACAGATGCCAACCTACCAGGAG
CTGGTGGAGGAGGCCATTGCTTACGGCAGGAAGCTGGGCGGGTCACAAGAGGAACAGATT
ACAAATGCTATTGATAAACTTTTTGTGTTGTTTGGGGCAGAAATACTGAAGAAAATTCCA
GGCCGCGTATCCACGGAAGTGGACGCCAGGCTCTCCTTTGATAAGGATGCGATGGTGGCC
CGCGCCCGGCGCCTCATTGAGCTGTACAAGGAGGCTGGGATCAGCAAGGAGCGGATCCTG
ATAAAGCTCTCGTCCACCTGGGAAGGAATTCAGGCCGGAAAGGAGCTGGAGGAGCACCAC
GGCATCCGGTGCAACATGACCCTGCTCTTCTCCTTCGCCCAGGCCGTGGCCTGCGCCGAG
GCCGGCGTGACGCTCATCTCGCCCTTCGTGGGCCGCATCCTTGACTGGCATGTGGCCAAC
ACAGACAAGAAGTCCTACGAAACCCAGGAGGACCCCGGAGTGAAGAGCGTCACCAAGATC
TACAACTATTACAAGAAGTTCGGCTACAAGACCATCGTCATGGGTGCCTCCTTCCGCAAC
ACGGGCGAGATCAAGGCCCTGGCTGGCTGTGACTTCCTCACCATCTCGCCCCAGCTCCTG
GGGGAGCTGCTCAAGGACCACAGCAAGCTGACGCCTGTGCTCTCGGCCAAAGCAGCCCAG
GCCAGTGACCTGGAGAAGATCCAGCTGGACGAGAAGGCCTTCCGCTGGCTGCACAACGAG
GACCGCATGGCTGTGGAGAAGCTCTCTGACGGGATCCGCAGGTTCGCCGCGGACGCGGTG
AAGCTGGAGCGGATGCTGAGAGAACGAATGTTCAGCGCAGAGAATGGAAAATAG
Enzyme 1 GenBank Gene ID BC109965 Link Image
Enzyme 1 GeneCard ID TALDO1 Link Image
Enzyme 1 GenAtlas ID Not Available
Enzyme 1 HGNC ID Not Available
Enzyme 1 Chromosome Location Chromosome:1
Enzyme 1 Locus 11p15.5-p15.4
Enzyme 1 SNPs SNPJam Report Link Image
Enzyme 1 General References Not Available
Enzyme 1 Metabolite References Not Available
Enzyme 2 [top]
Enzyme 2 ID 104
Enzyme 2 Name Transaldolase
Enzyme 2 Synonyms Not Available
Enzyme 2 Gene Name TALDO1
Enzyme 2 Protein Sequence >Transaldolase
MSGSPVKRQRMENALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPTYQE
LVEEAIAYGRKLGGSQEEQITNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVA
RARRLIELYKEAGISKERILIKLSSTWEGIQAGKELEEHHGIRCNMTLLFSFAQAVACAE
AGVTLISPFVGRILDWHVANTDKKSYEPQRTPE
Enzyme 2 Number of Residues 213
Enzyme 2 Molecular Weight 23711.9
Enzyme 2 Theoretical pI 5.74
Enzyme 2 GO Classification
Function
Process
Component
Enzyme 2 General Function Carbohydrate transport and metabolism
Enzyme 2 Specific Function Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Enzyme 2 Pathways
  • Carbohydrate degradation
  • pentose phosphate pathway
  • D- glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D- ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage):step 2/3
Enzyme 2 Reactions Not Available
Enzyme 2 Pfam Domain Function
Enzyme 2 Signals
  • None
Enzyme 2 Transmembrane Regions
  • None
Enzyme 2 Essentiality Not Available
Enzyme 2 GenBank ID Protein 61553289 Link Image
Enzyme 2 UniProtKB/Swiss-Prot ID Q58DR3 Link Image
Enzyme 2 UniProtKB/Swiss-Prot Entry Name Q58DR3_BOVIN Link Image
Enzyme 2 PDB ID 1F05 Link Image
Enzyme 2 PDB File Show
Enzyme 2 3D Structure
Enzyme 2 Cellular Location Not Available
Enzyme 2 Gene Sequence >642 bp
ATGTCGGGCTCCCCGGTGAAGCGGCAGAGGATGGAGAACGCGCTGGACCAGCTCAAGCAG
TTCACCACCGTGGTGGCCGACACGGGCGACTTCCACGCCATCGACGAGTACAAGCCCCAG
GATGCCACCACCAACCCGTCCCTGATCCTGGCTGCGGCACAGATGCCAACCTACCAGGAG
CTGGTGGAGGAGGCCATTGCTTACGGCAGGAAGCTGGGCGGGTCACAAGAGGAACAGATT
ACAAATGCTATTGATAAACTTTTTGTGTTGTTTGGGGCAGAAATACTGAAGAAAATTCCA
GGCCGCGTATCCACGGAAGTGGACGCCAGGCTCTCCTTTGATAAGGATGCGATGGTGGCC
CGCGCCCGGCGCCTCATTGAGCTGTACAAGGAGGCTGGGATCAGCAAGGAGCGGATCCTG
ATAAAGCTCTCGTCCACCTGGGAAGGAATTCAGGCCGGAAAGGAGCTGGAGGAGCACCAC
GGCATCCGGTGCAACATGACCCTGCTCTTCTCCTTCGCCCAGGCCGTGGCCTGCGCCGAG
GCCGGCGTGACGCTCATCTCGCCCTTCGTGGGCCGCATCCTTGACTGGCATGTGGCCAAC
ACAGACAAGAAGTCCTACGAACCCCAGAGGACCCCGGAGTGA
Enzyme 2 GenBank Gene ID BT021534 Link Image
Enzyme 2 GeneCard ID TALDO1 Link Image
Enzyme 2 GenAtlas ID Not Available
Enzyme 2 HGNC ID Not Available
Enzyme 2 Chromosome Location Chromosome:1
Enzyme 2 Locus 11p15.5-p15.4
Enzyme 2 SNPs SNPJam Report Link Image
Enzyme 2 General References
  1. [PubMed Link Image]
Enzyme 2 Metabolite References Not Available
Enzyme 3 [top]
Enzyme 3 ID 140
Enzyme 3 Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Enzyme 3 Synonyms
  1. 6PF-2-K/Fru-2,6-P2ASE liver isozyme
  2. 6-phosphofructo-2-kinase
  3. Fructose-2,6-bisphosphatase
Enzyme 3 Gene Name PFKFB1
Enzyme 3 Protein Sequence >6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
MSQEMGELTQTRLQKIWIPHNNGNSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
KLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALLIRKQCALAALKDVHSYL
SHEEGRVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPDVIAENIRQVKLGSPD
YIDCDREKVLEDFLKRIECYEVNYQPLDDELDSHLSYIKIFDVGTRYMVNRVQDHIQSRT
VYYLMNIHVTPRSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIQSQGISSLK
VGTSHMKRTIQTAEALGLPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY
RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH
TVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
Enzyme 3 Number of Residues 471
Enzyme 3 Molecular Weight 54656.8
Enzyme 3 Theoretical pI 6.51
Enzyme 3 GO Classification
Function
Process
Component
Enzyme 3 General Function Carbohydrate transport and metabolism
Enzyme 3 Specific Function Synthesis and degradation of fructose 2,6-bisphosphate
Enzyme 3 Pathways Not Available
Enzyme 3 Reactions Not Available
Enzyme 3 Pfam Domain Function
Enzyme 3 Signals
  • None
Enzyme 3 Transmembrane Regions
  • None
Enzyme 3 Essentiality Not Available
Enzyme 3 GenBank ID Protein 163518 Link Image
Enzyme 3 UniProtKB/Swiss-Prot ID P49872 Link Image
Enzyme 3 UniProtKB/Swiss-Prot Entry Name F261_BOVIN Link Image
Enzyme 3 PDB ID 1K6M Link Image
Enzyme 3 PDB File Show
Enzyme 3 3D Structure
Enzyme 3 Cellular Location Not Available
Enzyme 3 Gene Sequence >1416 bp
ATGTCTCAAGAGATGGGAGAGCTCACCCAAACCAGATTGCAGAAGATCTGGATTCCACAC
AACAACGGCAACAGCAGGCTTCAACGGAGGAGGGGCTCATCCATACCACAGTTTACAAAT
TCCCCCACAATGGTGATCATGGTGGGTTTACCAGCTCGAGGAAAGACCTACATCTCAACA
AAGCTCACACGCTATCTCAACTGGATAGGAACACCAACTAAAGTGTTTAATTTAGGCCAA
TATCGACGAGAGGCAGTGAGCTACAAGAACTACGAATTCTTTCTTCCCGACAACATGGAG
GCCCTACTTATCAGGAAGCAGTGTGCCCTAGCAGCCCTGAAAGATGTTCATAGCTATCTC
AGCCATGAGGAAGGTCGTGTTGCAGTTTTTGATGCCACCAACACTACCAGAGAACGACGG
TCACTGATTCTGCAGTTTGCTAAAGAACATGGTTACAAGGTCTTTTTCATTGAGTCCATT
TGTAATGACCCTGACGTCATTGCAGAAAACATCAGGCAAGTGAAACTTGGCAGTCCTGAT
TATATAGACTGTGATCGTGAAAAGGTTCTGGAAGATTTTCTAAAGAGAATAGAGTGCTAT
GAGGTCAACTACCAACCCTTGGATGATGAACTGGATAGCCACCTGTCCTACATCAAGATC
TTCGACGTGGGCACACGCTACATGGTGAATCGTGTGCAGGACCATATCCAGAGCCGCACA
GTCTACTATCTCATGAACATTCACGTCACACCCCGCTCCATCTACCTATGCCGGCACGGT
GAGAGTGAACTCAACCTCAGAGGCCGCATTGGAGGTGACTCTGGCCTCTCAGCTCGGGGC
AAGCAGTATGCCTATGCCCTGGCCAATTTCATTCAGTCCCAGGGTATCAGCTCACTGAAG
GTTGGGACCAGCCACATGAAGAGGACTATCCAGACAGCTGAAGCCTTAGGACTTCCCTAT
GAGCAATGGAAGGCCCTGAATGAGATTGATGCGGGTGTCTGTGAGGAGATGACCTATGAA
GAAATCCAAGAACACTACCCTGAAGAATTTGCACTGCGAGACCAAGATAAATACCGCTAC
CGCTATCCTAAGGGAGAGTCTTACGAGGATCTGGTCCAGCGTCTGGAGCCAGTTATAATG
GAGCTAGAACGGCAGGAAAATGTATTGGTGATCTGCCATCAGGCTGTCATGCGGTGCCTC
CTGGCCTACTTTCTGGACAAGAGCTCAGATGAGTTGCCTTATCTCAAGTGCCCTCTCCAC
ACAGTGCTCAAACTTACACCTGTGGCTTATGGCTGCAAAGTGGAGTCCATCTACCTGAAT
GTGGAGGCTGTAAACACACATCGGGAGAAACCTGAGAATGTGGACATCACCCGGGAACCT
GAAGAAGCCCTGGACACTGTTCCTGCCCACTACTGA
Enzyme 3 GenBank Gene ID M64323 Link Image
Enzyme 3 GeneCard ID PFKFB1 Link Image
Enzyme 3 GenAtlas ID Not Available
Enzyme 3 HGNC ID Not Available
Enzyme 3 Chromosome Location Not Available
Enzyme 3 Locus Xp11.21
Enzyme 3 SNPs SNPJam Report Link Image
Enzyme 3 General References
  1. [PubMed Link Image]
Enzyme 3 Metabolite References Not Available
Enzyme 4 [top]
Enzyme 4 ID 150
Enzyme 4 Name Fructose-1,6-bisphosphatase isozyme 2
Enzyme 4 Synonyms
  1. FBPase 2
  2. D-fructose-1,6-bisphosphate 1-phosphohydrolase 2
Enzyme 4 Gene Name FBP2
Enzyme 4 Protein Sequence >Fructose-1,6-bisphosphatase isozyme 2
MGDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLANLYGI
AGSVNVTGDEVKKLDVLSNALVINMLQSSYSTCVLVSEENKEAIITSKEKRGKYVVCFDP
LDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQPGRNIVAAGYALYGSATLVALSTGQ
GVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAP
YGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGT
QPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQAGR
Enzyme 4 Number of Residues 339
Enzyme 4 Molecular Weight 36766.9
Enzyme 4 Theoretical pI 7.81
Enzyme 4 GO Classification
Function
Process
Component
Enzyme 4 General Function Carbohydrate transport and metabolism
Enzyme 4 Specific Function D-fructose 1,6-bisphosphate + H(2)O = D- fructose 6-phosphate + phosphate
Enzyme 4 Pathways
  • Carbohydrate biosynthesis
  • gluconeogenesis
Enzyme 4 Reactions Not Available
Enzyme 4 Pfam Domain Function
Enzyme 4 Signals
  • None
Enzyme 4 Transmembrane Regions
  • None
Enzyme 4 Essentiality Not Available
Enzyme 4 GenBank ID Protein 86823226 Link Image
Enzyme 4 UniProtKB/Swiss-Prot ID Q2KJJ9 Link Image
Enzyme 4 UniProtKB/Swiss-Prot Entry Name F16P2_BOVIN Link Image
Enzyme 4 PDB ID Not Available
Enzyme 4 Cellular Location Not Available
Enzyme 4 Gene Sequence >1020 bp
ATGGGGGACAGAAGCCCCTTCGAAACGGACATGCTCACCCTGACCCGCTATGTTATGGAA
AAGGGGCGTCAGGCCAAAGGCACCGGGGAGCTCACGCAGCTGCTCAACTCCATGCTGACG
GCCATCAAAGCCATCTCCTCAGCTGTGCGTAAGGCGGGCCTGGCCAACCTGTACGGAATC
GCGGGAAGCGTGAACGTGACGGGGGATGAGGTGAAGAAACTGGACGTGTTATCCAATGCC
CTGGTGATCAACATGCTCCAGTCCTCCTACAGCACCTGCGTCCTGGTGTCGGAAGAGAAT
AAAGAAGCCATTATCACCTCCAAGGAGAAGAGGGGGAAATACGTGGTCTGCTTTGACCCT
CTGGACGGATCTTCCAACATTGACTGCCTGGCTTCCATTGGAACCATATTTGCCATCTAC
AGAAAGACCTCAGAGGATGAGCCTTCTGAAAAGGATGCCCTGCAGCCAGGTCGCAACATT
GTGGCTGCTGGCTATGCACTCTATGGAAGTGCAACCCTGGTGGCTCTTTCCACAGGGCAA
GGAGTGGACCTCTTCATGCTTGACCCAGCTCTTGGTGAATTTGTCTTGGTGGAAAAAGAT
GTCAAGATTAAAAAGAAAGGAAAGATTTACAGCCTCAACGAGGGCTATGCCAAGTATTTT
GATGCTGCCACCACAGAATATGTGCAGAAAAAGAAGTTTCCTGAGGACGGCAGTGCTCCC
TATGGGGCCAGGTACGTGGGCTCCATGGTGGCTGATGTGCACCGCACCCTTGTCTATGGA
GGGATCTTCCTGTACCCAGCAAACCAGAAAAGTCCGAAGGGCAAGCTCCGGCTCCTGTAT
GAGTGCAATCCTGTGGCCTACATCATCGAGCAGGCGGGAGGGCTGGCGACCACAGGCACC
CAACCCGTGCTGGACGTGAAGCCTGAAGCCATTCACCAACGAGTCCCCCTCATTCTAGGG
TCCCCAGAAGATGTACAGGAATATCTCACCTGTGTACAGAAAAATCAGGCAGGCAGGTAG
Enzyme 4 GenBank Gene ID BC102390 Link Image
Enzyme 4 GeneCard ID FBP2 Link Image
Enzyme 4 GenAtlas ID Not Available
Enzyme 4 HGNC ID Not Available
Enzyme 4 Chromosome Location Chromosome:9
Enzyme 4 Locus 9q22.3
Enzyme 4 SNPs SNPJam Report Link Image
Enzyme 4 General References Not Available
Enzyme 4 Metabolite References Not Available
Enzyme 5 [top]
Enzyme 5 ID 155
Enzyme 5 Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Enzyme 5 Synonyms
  1. 6PF-2-K/Fru-2,6-P2ASE brain/placenta-type isozyme
  2. 6-phosphofructo-2-kinase
  3. Fructose-2,6-bisphosphatase
Enzyme 5 Gene Name PFKFB3
Enzyme 5 Protein Sequence >6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
MPLELTQSRVQKIWIPVDHRPSLPRTCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
WIGVPTKVFNLGEYRRDGVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLTKEGGQ
IAVFDATNTTRERRHMILHFPKENDFKVFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
RENAMDDFMKRINCYEASYQPLDPDNDDRDLSLIKVIDVGQRFLVNRVQDHIQRRIVYYL
MNIHWQPRTIYLCRHGESKHNLQGKIGGDSGLSSRGRKFANALSKFVEEQNLKDLKVWTS
QLKSTIQTAEALQLPYEQWKALNEIDAGVCEEMTYEEIKDTYPEEYALAEADKYYYRYPT
GESYQDLVQRLEPVIMELERQENVLVICHQAVCVCLLAYFLDKSAEEMPYLKCPLHAVLK
LTPIAYGCRVESIYLNVESVSTHRERSEDAKKGPNPLMRSNSH
Enzyme 5 Number of Residues 463
Enzyme 5 Molecular Weight 53583.8
Enzyme 5 Theoretical pI 7.66
Enzyme 5 GO Classification
Function
Process
Component
Enzyme 5 General Function Carbohydrate transport and metabolism
Enzyme 5 Specific Function Synthesis and degradation of fructose 2,6-bisphosphate
Enzyme 5 Pathways Not Available
Enzyme 5 Reactions Not Available
Enzyme 5 Pfam Domain Function
Enzyme 5 Signals
  • None
Enzyme 5 Transmembrane Regions
  • None
Enzyme 5 Essentiality Not Available
Enzyme 5 GenBank ID Protein 7544879 Link Image
Enzyme 5 UniProtKB/Swiss-Prot ID Q28901 Link Image
Enzyme 5 UniProtKB/Swiss-Prot Entry Name F263_BOVIN Link Image
Enzyme 5 PDB ID Not Available
Enzyme 5 Cellular Location Not Available
Enzyme 5 Gene Sequence Not Available
Enzyme 5 GenBank Gene ID S77845 Link Image
Enzyme 5 GeneCard ID PFKFB3 Link Image
Enzyme 5 GenAtlas ID Not Available
Enzyme 5 HGNC ID Not Available
Enzyme 5 Chromosome Location Chromosome:1
Enzyme 5 Locus 10p14-p15
Enzyme 5 SNPs SNPJam Report Link Image
Enzyme 5 General References
  1. [PubMed Link Image]
Enzyme 5 Metabolite References Not Available
Enzyme 6 [top]
Enzyme 6 ID 162
Enzyme 6 Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Enzyme 6 Synonyms
  1. PFK-2/FBPase-2
  2. 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme
  3. 6-phosphofructo-2-kinase
  4. Fructose-2,6-bisphosphatase
Enzyme 6 Gene Name PFKFB2
Enzyme 6 Protein Sequence >6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
MSGNPASSSEQNNNSYETKASLRISEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLT
RYLNWIGVPTKVFNLGVYRRQAVKSYKSYDFFRHDNEEAMKIRKQCALVALKDVKAYLTE
ESGQIAVFDATNTTRERRDLILNFAEENSFKVFFVESVCDDPDVIAANILEVKVSSPDYP
ERNRENVMDDFLKRIECYKVTYQPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKIV
YYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLKV
WTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLYR
YPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHT
IFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKSQTPVRMRRNSFTPLSSSNTIRRP
RNYSVGSRPLQPLSPLRALDTQEGADQPKTQAETSRAAHRLPSPAPPTSPS
Enzyme 6 Number of Residues 531
Enzyme 6 Molecular Weight 60810.7
Enzyme 6 Theoretical pI 8.41
Enzyme 6 GO Classification
Function
Process
Component
Enzyme 6 General Function Carbohydrate transport and metabolism
Enzyme 6 Specific Function Synthesis and degradation of fructose 2,6-bisphosphate
Enzyme 6 Pathways Not Available
Enzyme 6 Reactions Not Available
Enzyme 6 Pfam Domain Function
Enzyme 6 Signals
  • None
Enzyme 6 Transmembrane Regions
  • None
Enzyme 6 Essentiality Not Available
Enzyme 6 GenBank ID Protein 552322 Link Image
Enzyme 6 UniProtKB/Swiss-Prot ID P26285 Link Image
Enzyme 6 UniProtKB/Swiss-Prot Entry Name F262_BOVIN Link Image
Enzyme 6 PDB ID Not Available
Enzyme 6 Cellular Location Not Available
Enzyme 6 Gene Sequence >1596 bp
ATGTCCGGGAATCCTGCCTCTTCCTCAGAACAGAACAACAATAGCTATGAAACCAAAGCA
AGTCTCCGAATATCAGAGAAGAAATGTTCATGGGCATCTTACATGACAAACTCTCCAACC
CTCATCGTTATGATTGGCTTGCCAGCCCGTGGCAAAACCTACGTGTCCAAGAAACTTACA
CGCTACCTCAACTGGATTGGGGTGCCCACCAAAGTGTTTAATCTTGGGGTGTATCGGCGG
CAAGCAGTCAAGTCCTATAAGTCCTATGACTTCTTCCGGCATGACAACGAGGAGGCCATG
AAGATTCGCAAACAGTGTGCCCTGGTGGCACTGAAAGACGTGAAGGCGTATCTCACGGAG
GAGAGCGGGCAGATTGCGGTGTTTGATGCTACCAATACCACTCGAGAGAGGAGGGACTTG
ATTTTGAACTTTGCCGAGGAGAATTCTTTCAAGGTGTTCTTTGTGGAGTCCGTGTGCGAT
GATCCTGATGTCATTGCTGCCAACATCCTGGAGGTAAAGGTGTCGAGCCCCGACTACCCT
GAAAGGAACAGGGAGAATGTGATGGATGACTTCCTAAAGAGGATTGAGTGCTACAAAGTC
ACCTATCAACCCCTTGACCCAGACAGCCATGACAAGGATCTTTCTTTCATCAAGGTGATA
AACGTGGGCCAGAGATTTCTCGTGAACAAAGTCCAGGACTACATCCAGAGCAAGATCGTC
TACTACCTCATGAATATCCACGTCCACCCTCGCACCATCTACCTTTGCCGGCATGGAGAG
AGCGAGTTCAACCTCTTGGGGAAGATTGGGGGTGACTCAGGCCTCTCAGTGCGAGGAAAA
CAGTTTGCCCAGGCTCTAAGGAAGTTTCTGGAGGAACAGGAGATAGCAGACCTCAAAGTG
TGGACGAGCCAGTTGAAAAGGACTATCCAGACCGCAGAATCTCTGGGGGTGACCTACGAG
CAGTGGAAGATTCTGAACGAGATTGATGCTGGCGTGTGCGAGGAGATGACTTACGCGGAG
ATTCAGGAGCAGTATCCGGATGAGTTTGCGCTTCGAGATGAAGAGAAATATCTGTACCGA
TATCCTGGAGGGGAGTCATACCAGGACCTCGTGCAGCGGTTGGAGCCAGTCATCATGGAG
CTGGAGCGCCAGGGCAATGTCCTCGTTATCTCCCACCAGGCTGTCATGCGCTGCCTCCTG
GCCTACTTCTTGGACAAGGGTGCAGATGAGCTACCATACCTGAGGTGCCCTCTCCATACC
ATCTTCAAACTTACTCCTGTGGCCTACGGGTGCAAAGTGGAAACAATTAAACTCAATGTG
GAGGCTGTGAACACGCACCGTGACAAGCCAACTAACAACTTTCCCAAGAGCCAAACCCCT
GTAAGGATGAGAAGGAACAGCTTTACGCCTCTGTCCAGTTCGAATACAATCAGGCGTCCA
AGAAATTACAGTGTTGGGAGCCGGCCCCTCCAGCCCCTCAGCCCGCTCCGTGCCCTGGAC
ACGCAAGAAGGGGCCGACCAGCCGAAGACCCAAGCAGAGACCTCGCGGGCTGCACACAGG
CTCCCGTCTCCAGCGCCCCCCACGTCGCCCTCCTGA
Enzyme 6 GenBank Gene ID M34241 Link Image
Enzyme 6 GeneCard ID PFKFB2 Link Image
Enzyme 6 GenAtlas ID Not Available
Enzyme 6 HGNC ID Not Available
Enzyme 6 Chromosome Location Chromosome:1
Enzyme 6 Locus 1q31
Enzyme 6 SNPs SNPJam Report Link Image
Enzyme 6 General References
  1. [PubMed Link Image]
Enzyme 6 Metabolite References Not Available
Enzyme 7 [top]
Enzyme 7 ID 176
Enzyme 7 Name Fructose-1,6-bisphosphatase 1
Enzyme 7 Synonyms
  1. FBPase 1
  2. D-fructose-1,6-bisphosphate 1-phosphohydrolase 1
Enzyme 7 Gene Name FBP1
Enzyme 7 Protein Sequence >Fructose-1,6-bisphosphatase 1
MTDQAAFDTNIVTVTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGI
AGTTNVTGDQVKKLDVLSNDLVVNVLKSSFATCVLVSEEDEHAIIVEPEKRGKYVVCFDP
LDGSSNIDCLVSIGTIFGIYKKISKDDPSEKDALQPGRNLVAAGYALYGSATMLVLAMAN
GVNCFMLDPAIGEFILVDRDVKIKKKGSIYSLNEGYAKDFDPALTEYVQRKKFPPDNSAP
YGARYVGSMVADVHRTLVYGGIFMYPANKKSPSGKLRLLYECNPMAYVIEKAGGMATTGK
ETVLDIVPTDIHQKSPIILGSPEDVTEFLEIYKKHAAK
Enzyme 7 Number of Residues 338
Enzyme 7 Molecular Weight 36728.0
Enzyme 7 Theoretical pI 7.01
Enzyme 7 GO Classification
Function
Process
Component
Enzyme 7 General Function Carbohydrate transport and metabolism
Enzyme 7 Specific Function D-fructose 1,6-bisphosphate + H(2)O = D- fructose 6-phosphate + phosphate
Enzyme 7 Pathways
  • Carbohydrate biosynthesis
  • gluconeogenesis
Enzyme 7 Reactions Not Available
Enzyme 7 Pfam Domain Function
Enzyme 7 Signals
  • None
Enzyme 7 Transmembrane Regions
  • None
Enzyme 7 Essentiality Not Available
Enzyme 7 GenBank ID Protein 74354240 Link Image
Enzyme 7 UniProtKB/Swiss-Prot ID Q3SZB7 Link Image
Enzyme 7 UniProtKB/Swiss-Prot Entry Name F16P1_BOVIN Link Image
Enzyme 7 PDB ID 1NV7 Link Image
Enzyme 7 PDB File Show
Enzyme 7 3D Structure
Enzyme 7 Cellular Location Not Available
Enzyme 7 Gene Sequence >1017 bp
ATGACGGACCAGGCAGCCTTCGACACCAATATCGTCACCGTGACCCGCTTCGTCATGGAA
GAGGGCAGGAAGGCCCGTGGCACGGGCGAGATGACCCAACTGCTCAACTCGCTTTGCACC
GCGGTCAAAGCCATCTCCACGGCCGTGCGCAAGGCGGGCATCGCGCACCTCTATGGAATT
GCTGGCACTACCAATGTGACGGGAGATCAAGTGAAGAAGCTGGATGTCCTCTCCAATGAC
CTGGTTGTTAATGTGTTAAAGTCATCTTTTGCTACCTGTGTTCTTGTGTCAGAAGAAGAT
GAACATGCCATAATAGTAGAACCTGAGAAAAGGGGTAAATATGTGGTCTGTTTTGATCCC
CTTGATGGATCATCCAACATCGACTGCCTTGTGTCCATTGGAACCATCTTTGGCATCTAC
AAAAAGATTTCGAAAGATGACCCTTCTGAGAAGGACGCTCTGCAGCCAGGCCGGAACCTG
GTGGCTGCTGGCTATGCGCTCTATGGCAGTGCCACTATGTTGGTCCTGGCCATGGCGAAT
GGAGTCAACTGCTTCATGCTGGACCCGGCCATTGGAGAGTTCATTTTGGTGGACAGGGAT
GTGAAGATCAAAAAGAAAGGGAGCATCTATAGCCTCAATGAAGGCTATGCGAAGGACTTT
GATCCTGCCCTCACCGAGTATGTCCAGAGGAAGAAGTTCCCCCCAGACAACTCAGCCCCC
TATGGCGCCAGGTACGTGGGCTCCATGGTAGCCGATGTACACCGCACCCTAGTCTATGGA
GGGATCTTTATGTATCCAGCTAACAAGAAAAGCCCCAGTGGAAAGCTGAGACTACTGTAT
GAATGTAACCCCATGGCCTATGTCATAGAGAAGGCAGGAGGAATGGCTACCACCGGGAAG
GAAACTGTGCTGGACATTGTTCCCACTGACATCCATCAGAAGTCGCCCATCATCTTGGGG
TCTCCTGAAGATGTGACTGAGTTCCTGGAGATATACAAGAAGCATGCTGCCAAATGA
Enzyme 7 GenBank Gene ID BC102974 Link Image
Enzyme 7 GeneCard ID FBP1 Link Image
Enzyme 7 GenAtlas ID Not Available
Enzyme 7 HGNC ID Not Available
Enzyme 7 Chromosome Location Chromosome:9
Enzyme 7 Locus 9q22.3
Enzyme 7 SNPs SNPJam Report Link Image
Enzyme 7 General References Not Available
Enzyme 7 Metabolite References Not Available
Enzyme 8 [top]
Enzyme 8 ID 479
Enzyme 8 Name 6-phosphofructokinase, liver type
Enzyme 8 Synonyms
  1. Phosphofructokinase 1
  2. Phosphohexokinase
  3. Phosphofructo-1-kinase isozyme B
  4. PFK-B
Enzyme 8 Gene Name PFKL
Enzyme 8 Protein Sequence >6-phosphofructokinase, liver type
MASVDLEKLRTTGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVE
GGENIKQANWLSVSNIIQLGGTVIGSARCKAFTTREGRRAAAYNLVQRGITNLCVIGGDG
SLTGANIFRSEWGSLLEELVSEGKISEGTAQTYSHLNIAGLVGSIDNDFCGTDMTIGTDS
ALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWE
NFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSRYVKDLVVQRLGFDTRVTVLGHVQ
RGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQMTKEVQK
AMDEKRFDEAIQLRGGSFENNWNIYKLLSHQKISKEKTNFSLAILNVGAPAAGMNAAVRS
AVRSGISQGHTVYVVHDGFEGLAKNQVQEVSWHDVAGWLGRGGSMLGTKRTLPKGFMEKI
VENIRLHNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLG
SDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFN
IQDLKANVEHMTEKMKTEIQRGLVLRNEKCHEHYTTEFLYNLYSSEGKGVFDCRTNVLGH
LQQGGAPTPFDRNYGTKLGVKAIIWMSEKLRAVYRNGRVFANASDSACVIGLQKKVVAFS
PVTELKKDTDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIETGF
Enzyme 8 Number of Residues 780
Enzyme 8 Molecular Weight 85291.0
Enzyme 8 Theoretical pI 7.39
Enzyme 8 GO Classification
Function
Process
Component
Enzyme 8 General Function Carbohydrate transport and metabolism
Enzyme 8 Specific Function ATP + D-fructose 6-phosphate = ADP + D- fructose 1,6-bisphosphate
Enzyme 8 Pathways
  • Carbohydrate degradation
  • glycolysis
  • D-glyceraldehyde 3- phosphate and glycerone phosphate from D-glucose:step 3/4
Enzyme 8 Reactions Not Available
Enzyme 8 Pfam Domain Function
Enzyme 8 Signals
  • None
Enzyme 8 Transmembrane Regions
  • None
Enzyme 8 Essentiality Not Available
Enzyme 8 GenBank ID Protein 119223906 Link Image
Enzyme 8 UniProtKB/Swiss-Prot ID A1A4J1 Link Image
Enzyme 8 UniProtKB/Swiss-Prot Entry Name K6PL_BOVIN Link Image
Enzyme 8 PDB ID Not Available
Enzyme 8 Cellular Location Not Available
Enzyme 8 Gene Sequence >2343 bp
ATGGCCAGCGTGGATCTGGAGAAGCTGCGGACCACCGGGGCTGGCAAGGCCATCGGCGTG
CTGACCAGTGGCGGTGATGCGCAAGGCATGAATGCCGCTGTCAGAGCCGTGACTCGTATG
GGCATTTACGTGGGGGCCAAGGTCTTCCTCATCTACGAGGGCTATGAAGGCCTCGTGGAG
GGCGGCGAGAACATCAAGCAGGCCAACTGGCTGAGCGTCTCCAACATCATCCAGTTGGGC
GGCACCGTCATCGGCAGCGCCCGCTGCAAGGCCTTCACCACGCGGGAGGGACGCCGGGCG
GCCGCCTACAACCTGGTCCAGCGTGGCATCACCAACCTGTGCGTCATCGGCGGGGACGGC
AGCCTCACTGGGGCCAACATCTTCCGCAGCGAGTGGGGCAGCCTCCTGGAGGAGCTGGTG
AGCGAAGGCAAGATCTCAGAGGGCACGGCTCAGACCTATTCACACCTGAACATCGCGGGG
CTGGTGGGCTCCATCGACAATGACTTCTGTGGCACCGACATGACCATCGGCACAGACTCG
GCGCTGCACCGCATCATGGAAGTCATCGACGCCATCACCACCACTGCCCAGAGCCACCAG
AGGACCTTTGTGCTGGAGGTGATGGGACGGCACTGCGGGTACCTGGCCCTGGTGTCTGCC
CTGGCCTCGGGGGCCGACTGGCTGTTCATCCCTGAGGCGCCCCCTGAGGACGGCTGGGAG
AACTTCATGTGTGAGCGGCTCGGCGAGACTCGGAGCCGAGGGTCCCGCCTCAACATTATC
ATCATTGCTGAGGGCGCCATCGACCGCAACGGGAAGCCCATCTCGTCCCGCTACGTGAAG
GACCTGGTGGTCCAGAGACTGGGCTTCGACACGCGTGTGACTGTGCTGGGCCACGTGCAG
AGGGGAGGGACCCCCTCGGCATTCGACCGCATCCTGAGCAGTAAGATGGGCATGGAGGCG
GTGATGGCGCTGCTGGAGGCCACGCCCGACACGCCGGCCTGCGTGGTCAGCCTCTCGGGG
AACCAGTCCGTGCGGCTGCCCCTCATGGAGTGTGTGCAGATGACCAAGGAGGTGCAGAAG
GCCATGGACGAGAAGAGGTTTGACGAGGCCATCCAGCTCCGAGGCGGGAGCTTTGAGAAC
AACTGGAATATTTACAAGCTGCTTTCCCACCAGAAGATCTCCAAGGAGAAGACCAACTTC
TCCCTGGCCATCCTGAACGTGGGGGCCCCAGCAGCCGGCATGAACGCGGCCGTGCGCTCG
GCGGTGCGTTCTGGCATCTCCCAGGGCCACACGGTGTACGTTGTGCATGACGGCTTTGAA
GGCCTGGCCAAGAACCAGGTGCAAGAAGTGAGCTGGCATGACGTGGCCGGCTGGCTGGGG
CGTGGTGGCTCCATGCTGGGGACAAAGAGGACGCTGCCCAAAGGCTTCATGGAGAAAATT
GTGGAAAACATCCGCCTTCACAACATCCACGCCCTGCTGGTCATCGGGGGCTTTGAGGCC
TACGAGGGGGTGCTGCAGCTGGTGGAGGCCCGTGGGCGCTATGAGGAGCTGTGCATCGTC
ATGTGCGTCATCCCCGCCACCATCAGCAACAACGTGCCAGGCACGGACTTCAGCCTGGGC
TCCGACACGGCCGTCAACGCCGCCATGGAGAGTTGTGACCGCATCAAGCAGTCGGCCTCG
GGGACCAAGCGCCGTGTGTTCATCGTGGAGACCATGGGTGGCTACTGCGGCTACCTGGCT
ACTGTGACTGGCATTGCTGTGGGCGCCGACGCTGCCTATGTCTTCGAGGATCCCTTCAAC
ATTCAAGACTTAAAGGCCAATGTGGAGCACATGACCGAGAAGATGAAGACAGAGATCCAG
CGGGGCCTGGTACTCCGGAACGAGAAGTGCCACGAGCACTACACCACAGAGTTCCTGTAC
AACCTCTACTCCTCCGAGGGCAAGGGCGTGTTTGACTGCAGGACCAACGTCCTGGGCCAC
CTGCAGCAGGGTGGAGCTCCCACCCCCTTTGACCGGAACTATGGTACCAAGCTCGGGGTG
AAAGCCATAATCTGGATGTCGGAGAAGCTGCGGGCAGTCTATCGCAATGGGCGGGTGTTT
GCCAATGCCTCTGACTCGGCCTGCGTGATTGGCCTGCAGAAGAAAGTGGTGGCCTTCAGC
CCTGTCACCGAGCTCAAGAAAGACACCGACTTTGAGCACCGCATGCCCCGGGAGCAGTGG
TGGCTGAACCTGCGGCTCATGCTGAAGATGCTGGCACACTACCGCATCAGCATGGCTGAC
TACGTGTCCGGGGAGCTGGAGCACGTCACCCGCCGCACCCTCAGCATTGAGACGGGCTTC
TGA
Enzyme 8 GenBank Gene ID BC126578 Link Image
Enzyme 8 GeneCard ID PFKL Link Image
Enzyme 8 GenAtlas ID Not Available
Enzyme 8 HGNC ID Not Available
Enzyme 8 Chromosome Location Chromosome:2
Enzyme 8 Locus 21q22.3
Enzyme 8 SNPs SNPJam Report Link Image
Enzyme 8 General References Not Available
Enzyme 8 Metabolite References Not Available
Enzyme 9 [top]
Enzyme 9 ID 523
Enzyme 9 Name 6-phosphofructokinase, muscle type
Enzyme 9 Synonyms
  1. Phosphofructokinase 1
  2. Phosphohexokinase
  3. Phosphofructo-1-kinase isozyme A
  4. PFK-A
  5. Phosphofructokinase-M
Enzyme 9 Gene Name PFKM
Enzyme 9 Protein Sequence >6-phosphofructokinase, muscle type
MTHEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIYTGARVFFVHEGYQGLVDG
GDNIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGS
LTGADTFRSEWSDLLSDLQKSGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSA
LHRIIEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEE
HLCRRLSETRNRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQR
GGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTRA
MDERRFDEALKLRGRSFMNNWEVYKLLAHVRPPKSKSGSHTVAVMNVGAPAAGMNAAVRS
TVRIGLIQGNRMLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQI
SANITKFNIQGLVIIGGFEAYTGGLELMEGRKQYDELCIPFVVIPATVSNNVPGSDFSVG
ADTALNTICMTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEDPFT
IRDLQVNVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGH
MQQGGSPTPFDRNFATKMGAKAMNWMSGKIKESYRNGRIFANSPDSGCVLGMRKRALVFQ
PVTELKEQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSEHAHLEHISRKRSGEANV
Enzyme 9 Number of Residues 779
Enzyme 9 Molecular Weight 85293.0
Enzyme 9 Theoretical pI 8.37
Enzyme 9 GO Classification
Function
Process
Component
Enzyme 9 General Function Carbohydrate transport and metabolism
Enzyme 9 Specific Function ATP + D-fructose 6-phosphate = ADP + D- fructose 1,6-bisphosphate
Enzyme 9 Pathways
  • Carbohydrate degradation
  • glycolysis
  • D-glyceraldehyde 3- phosphate and glycerone phosphate from D-glucose:step 3/4
Enzyme 9 Reactions Not Available
Enzyme 9 Pfam Domain Function
Enzyme 9 Signals
  • None
Enzyme 9 Transmembrane Regions
  • None
Enzyme 9 Essentiality Not Available
Enzyme 9 GenBank ID Protein 113911829 Link Image
Enzyme 9 UniProtKB/Swiss-Prot ID Q0IIG5 Link Image
Enzyme 9 UniProtKB/Swiss-Prot Entry Name K6PF_BOVIN Link Image
Enzyme 9 PDB ID Not Available
Enzyme 9 Cellular Location Not Available
Enzyme 9 Gene Sequence >2340 bp
ATGACCCATGAGCACCATGCAGCCAAAACCCTGGGAATCGGCAAAGCCATCGCCGTGTTA
ACCTCTGGTGGCGATGCCCAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGTGTTGGC
ATCTATACTGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTAGATGGT
GGAGATAACATCCGGGAAGCCACATGGGAGAGTGTCTCGATGATGCTTCAGCTGGGAGGC
ACGGTGATTGGAAGCGCCCGGTGCAAGGACTTTCGGGAACGGGAAGGCCGGCTCCGAGCT
GCCCACAACCTGGTGAAACGTGGGATCACCAACCTGTGTGTCATTGGGGGAGACGGCAGC
CTGACTGGGGCCGACACCTTCCGCTCTGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAA
TCAGGCAAGATTACAGCAGAGGAGGCTACCAAGTCCAGCTACCTGAACATCGTGGGGCTG
GTTGGCTCAATTGACAATGACTTCTGTGGCACTGATATGACCATTGGCACCGACTCTGCC
CTGCACCGGATCATAGAGATTGTAGATGCCATCACTACTACCGCTCAGAGCCACCAGAGG
ACCTTTGTGTTGGAGGTGATGGGCCGGCACTGTGGATACCTGGCCCTTGTCACTTCCCTC
TCCTGTGGGGCCGACTGGGTCTTTATTCCCGAGTGTCCACCAGATGACGACTGGGAGGAA
CACCTTTGTCGCCGGCTCAGCGAGACAAGGAACCGTGGTTCTCGTCTCAACATCATCATC
GTAGCTGAGGGTGCGATTGACAAGAATGGGAAACCAATCACCTCTGAAGACATCAAAAAC
CTGGTGGTTAAGCGTCTGGGATATGACACCCGAGTCACCGTCTTGGGGCACGTGCAGCGG
GGTGGGACACCGTCGGCCTTTGACAGAATCCTGGGCAGCAGGATGGGTGTGGAAGCAGTA
ATGGCACTTTTGGAGGGGACCCCGGACACCCCAGCCTGTGTGGTGAGCCTCTCTGGTAAC
CAGGCTGTGCGCCTGCCCCTCATGGAGTGTGTCCAGGTGACCAAGGACGTGACCAGGGCC
ATGGATGAAAGGAGATTCGATGAGGCCTTGAAGCTGAGGGGCCGGAGCTTCATGAACAAC
TGGGAGGTATACAAGCTTCTGGCTCACGTCAGACCCCCAAAGTCTAAGAGTGGCTCCCAC
ACGGTGGCCGTGATGAACGTGGGAGCGCCGGCCGCAGGCATGAACGCAGCCGTTCGCTCC
ACTGTGAGAATCGGCCTCATCCAGGGCAACCGAATGCTGGTGGTGCACGATGGCTTCGAG
GGCCTGGCCAAGGGTCAGATCGAGGAAGCTGGATGGAGCTACGTCGGGGGCTGGACTGGC
CAAGGTGGTTCTAAACTTGGGACTAAAAGGACTCTACCCAAGAAGAGCTTTGAACAGATC
AGTGCCAACATCACGAAGTTTAATATTCAGGGCCTTGTCATTATCGGGGGCTTTGAGGCT
TACACGGGGGGCCTGGAGCTGATGGAAGGCAGGAAGCAGTATGATGAGCTCTGCATCCCC
TTCGTGGTCATCCCTGCCACGGTCTCCAACAATGTGCCCGGCTCGGACTTCAGCGTGGGG
GCTGACACTGCCCTCAACACCATCTGCATGACGTGTGACCGCATCAAGCAGTCAGCGGCA
GGCACCAAGCGCCGTGTGTTTATCATTGAAACGATGGGCGGCTACTGTGGCTACCTGGCC
ACCATGGCAGGCCTGGCAGCTGGGGCTGATGCTGCGTATATTTTTGAGGACCCCTTCACC
ATTCGAGACCTGCAGGTGAATGTGGAGCATCTGGTGCAGAAGATGAAAACGACTGTGAAG
AGGGGCCTGGTGTTAAGGAACGAGAAGTGCAATGAGAACTACACCACTGACTTCATCTTC
AACTTGTACTCTGAGGAGGGGAAGGGCATCTTCGACAGCAGGAAGAACGTGCTGGGCCAC
ATGCAGCAGGGTGGGAGCCCAACTCCATTCGACAGGAATTTTGCCACTAAGATGGGTGCA
AAGGCTATGAACTGGATGTCAGGGAAAATCAAAGAGAGTTACCGTAATGGGCGGATCTTT
GCCAATTCCCCAGACTCGGGCTGTGTTCTGGGGATGCGTAAGAGGGCCCTGGTCTTCCAA
CCAGTGACTGAGTTGAAGGAACAGACGGATTTTGAGCACCGCATCCCCAAGGAGCAGTGG
TGGCTGAAGCTGAGGCCCATCCTCAAGATCCTCGCCAAGTACGAGATTGACTTGGATACC
TCAGAGCACGCCCACCTGGAGCACATCTCTCGGAAGCGGTCCGGAGAAGCTAACGTCTAG
Enzyme 9 GenBank Gene ID BC122655 Link Image
Enzyme 9 GeneCard ID PFKM Link Image
Enzyme 9 GenAtlas ID Not Available
Enzyme 9 HGNC ID Not Available
Enzyme 9 Chromosome Location Chromosome:1
Enzyme 9 Locus 12q13.3
Enzyme 9 SNPs SNPJam Report Link Image
Enzyme 9 General References Not Available
Enzyme 9 Metabolite References Not Available
Enzyme 10 [top]
Enzyme 10 ID 827
Enzyme 10 Name Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2
Enzyme 10 Synonyms
  1. Glutamine:fructose 6 phosphate amidotransferase 2
  2. GFAT 2
  3. GFAT2
  4. D-fructose-6-phosphate amidotransferase 2
  5. Hexosephosphate aminotransferase 2
Enzyme 10 Gene Name GFPT2
Enzyme 10 Protein Sequence >Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2
MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNNEVKERHIQLVKKR
GNVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHN
GIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEG
AFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTRNIENVKNICKTRMK
RLDSSTCLHAVGNKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRLAS
DDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDH
LKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFF
ISQSGETADTLLALRYCKDRRALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYT
SQFISLVMFGLMMSEDRISLQNRRREIIHGLKSLPELIKEVLSLDEKIHDLALELYTQRS
LLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCF
AKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFH
LAVLRGYDVDFPRNLAKSVTVE
Enzyme 10 Number of Residues 682
Enzyme 10 Molecular Weight 77080.1
Enzyme 10 Theoretical pI 7.72
Enzyme 10 GO Classification
Function
Process
Component
Enzyme 10 General Function Cell wall/membrane/envelope biogenesis
Enzyme 10 Specific Function Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins
Enzyme 10 Pathways
  • Nucleotide-sugar biosynthesis
  • UDP-N-acetyl-alpha-D- glucosamine biosynthesis
  • alpha-D-glucosamine 6-phosphate from D- fructose 6-phosphate:step 1/1
Enzyme 10 Reactions Not Available
Enzyme 10 Pfam Domain Function
Enzyme 10 Signals
  • None
Enzyme 10 Transmembrane Regions
  • None
Enzyme 10 Essentiality Not Available
Enzyme 10 GenBank ID Protein 115304901 Link Image
Enzyme 10 UniProtKB/Swiss-Prot ID Q08DQ2 Link Image
Enzyme 10 UniProtKB/Swiss-Prot Entry Name GFPT2_BOVIN Link Image
Enzyme 10 PDB ID Not Available
Enzyme 10 Cellular Location Not Available
Enzyme 10 Gene Sequence >2049 bp
ATGTGCGGAATCTTTGCCTACATGAATTACAGAGTCCCCCGGACAAGGAAGGAGATTTTT
GAAACCCTCATCAAGGGCCTGCAGCGGCTTGAGTACAGAGGCTATGACTCAGCAGGTGTG
GCAATTGATGGAAATAATAATGAAGTCAAAGAAAGGCATATCCAGCTCGTCAAGAAAAGA
GGAAATGTCAAAGCTCTTGATGAAGAACTTTACAAACAAGACAGCATGGACTTAAAAGTG
GAGTTTGAGACCCACTTTGGCATTGCCCACACACGGTGGGCCACTCACGGGGTCCCCAGT
GCTGTCAACAGCCACCCGCAGCGCTCAGACAAGGGCAACGAATTCGTTGTCATCCATAAT
GGGATCATCACAAATTACAAAGACCTGAGGAAATTTCTGGAAAGCAAAGGCTATGAGTTT
GAGTCAGAAACAGATACAGAAACCATTGCCAAGCTGATTAAATATGTGTTCGACAACAGA
GAAACCGAGGACATTACATTTTCAACACTGGTGGAGAGAGTCATTCAGCAGCTGGAAGGC
GCATTTGCCTTGGTTTTCAAGAGCATCCACTACCCTGGAGAAGCCGTGGCCACAAGGAGA
GGCAGTCCCCTACTCATCGGAGTAAGGAGCAAATACAAACTCTCCACAGAACAGATCCCC
GTCTTATATAGGACACGCAATATTGAGAATGTGAAGAATATCTGTAAAACAAGGATGAAG
AGGCTGGACAGCTCGACCTGCCTTCACGCTGTGGGCAATAAAGCAGTGGAATTCTTTTTT
GCTTCTGATGCAAGTGCTATCATAGAGCACACCAACCGGGTCATCTTCCTTGAGGATGAT
GACATTGCCGCAGTGGCTGATGGGAAACTCTCTATTCACCGGGTCAAGCGTTTGGCTAGT
GATGACCCATCTCGAGCCATCCAGACCTTGCAGATGGAATTGCAGCAAATCATGAAAGGT
AACTTCAGTGCATTTATGCAAAAGGAGATATTTGAACAGCCAGAATCCGTTTTCAATACC
ATGAGAGGTCGAGTGAATTTTGAGACCAACACAGTGCTCCTGGGTGGCTTGAAAGACCAC
TTGAAGGAGATCAGACGATGCCGACGGCTCATTGTGATTGGCTGTGGGACCAGCTACCAC
GCCGCTGTGGCCACGCGGCAAGTTTTGGAGGAACTGACCGAGCTCCCCGTGATGGTTGAA
CTTGCTAGTGATTTTCTGGACAGGAACACACCTGTGTTCAGGGATGACGTTTGCTTTTTC
ATAAGCCAGTCAGGGGAGACTGCAGACACCCTCCTGGCACTGCGCTACTGCAAGGACCGC
CGAGCTCTGACCGTGGGCGTCACCAACACCGTGGGCAGCTCCATCTCCCGCGAGACGGAC
TGCGGCGTCCACATCAACGCAGGGCCGGAGATCGGTGTGGCCAGCACCAAGGCTTACACC
AGTCAGTTCATCTCCTTGGTGATGTTTGGTTTGATGATGTCTGAAGACCGCATTTCACTG
CAAAACAGAAGGCGAGAGATCATCCATGGCCTGAAATCTCTACCCGAGCTGATCAAGGAG
GTGCTGTCCCTGGATGAGAAGATCCACGACCTGGCCCTGGAGCTCTACACACAAAGGTCA
CTTCTGGTCATGGGGCGAGGCTACAACTATGCCACATGCCTGGAAGGAGCCCTGAAAATT
AAAGAGATAACCTACATGCACTCAGAAGGCATCCTGGCTGGAGAGTTGAAGCACGGCCCC
CTGGCGCTGATTGATAAGCAGATGCCTGTCATCATGGTCATCATGAAGGATCCTTGCTTT
GCCAAATGCCAGAACGCCCTGCAGCAGGTCACAGCGCGCCAGGGTCGCCCGATTATACTG
TGCTCCAAGGACGACACTGAAAGCTCCAAGTTTGCATATAAAACGATCGAGCTGCCCCAC
ACCGTAGACTGCCTGCAGGGCATCCTGAGTGTGATTCCACTGCAGCTCCTCTCCTTCCAC
CTGGCTGTACTCCGAGGATATGACGTTGACTTCCCCAGAAATCTGGCCAAGTCTGTAACC
GTGGAATGA
Enzyme 10 GenBank Gene ID BC123624 Link Image
Enzyme 10 GeneCard ID GFPT2 Link Image
Enzyme 10 GenAtlas ID Not Available
Enzyme 10 HGNC ID Not Available
Enzyme 10 Chromosome Location Chromosome:5
Enzyme 10 Locus 5q34-q35
Enzyme 10 SNPs SNPJam Report Link Image
Enzyme 10 General References Not Available
Enzyme 10 Metabolite References Not Available
Enzyme 11 [top]
Enzyme 11 ID 1129
Enzyme 11 Name Probable fructose-2,6-bisphosphatase TIGAR
Enzyme 11 Synonyms
  1. TP53-induced glycolysis and apoptosis regulator
Enzyme 11 Gene Name TIGAR
Enzyme 11 Protein Sequence >Probable fructose-2,6-bisphosphatase TIGAR
MTRFALTVVRHGETRLNKEKIIQGQGIDEPLSETGFKQAAAAGIFLKDVKFTHVFSSDLT
RTKQTVHGILEKSKFCKDMTVKYDSRLRERKYGVAEGRPLSELRAMAKAAGEECPAFTPP
GGETLDQLKRRGKDFFEFLCQLILKEAGQNEQFSQEAPSSCLESSLAEIFPLGKNCASTF
NSDSGTPGLAASVLVVSHGAYIRSLLDYFLTDLKCSFPATLSRSELTSVSPNTGMTVFIL
NFEKGGKGRPTAQCVCVNLQGHLAGVNKTP
Enzyme 11 Number of Residues 270
Enzyme 11 Molecular Weight 29466.5
Enzyme 11 Theoretical pI 8.57
Enzyme 11 GO Classification
Function
Process
Component
Enzyme 11 General Function Carbohydrate transport and metabolism
Enzyme 11 Specific Function Probable fructose-biphosphatase. Lowers cellular levels of fructose 2,6-bisphosphate. Protects cells against reactive oxygen species and against apoptosis induced by TP53
Enzyme 11 Pathways Not Available
Enzyme 11 Reactions Not Available
Enzyme 11 Pfam Domain Function
Enzyme 11 Signals
  • None
Enzyme 11 Transmembrane Regions
  • None
Enzyme 11 Essentiality Not Available
Enzyme 11 GenBank ID Protein 94574108 Link Image
Enzyme 11 UniProtKB/Swiss-Prot ID Q1JQA7 Link Image
Enzyme 11 UniProtKB/Swiss-Prot Entry Name TIGAR_BOVIN Link Image
Enzyme 11 PDB ID Not Available
Enzyme 11 Cellular Location Not Available
Enzyme 11 Gene Sequence >813 bp
ATGACGCGCTTCGCTCTGACCGTGGTCCGGCATGGAGAAACAAGACTTAACAAGGAGAAA
ATAATTCAAGGACAAGGAATAGATGAGCCTCTTTCAGAAACTGGATTTAAACAAGCAGCT
GCTGCTGGTATATTTCTTAAAGATGTGAAGTTTACTCATGTTTTCTCCAGTGACCTTACA
AGGACAAAGCAGACCGTGCATGGGATTTTGGAGAAGAGCAAATTTTGCAAAGATATGACA
GTAAAGTATGATTCAAGACTCCGAGAAAGGAAATATGGGGTTGCAGAAGGCAGGCCGCTG
AGCGAGCTGAGGGCCATGGCCAAAGCGGCAGGGGAGGAGTGCCCAGCATTCACACCGCCT
GGAGGAGAGACCTTGGACCAGCTGAAAAGGCGTGGGAAAGACTTTTTTGAATTTCTTTGT
CAACTGATCCTGAAAGAAGCCGGTCAGAATGAACAGTTTTCCCAGGAAGCCCCGAGCAGC
TGTCTGGAAAGTTCCCTGGCAGAGATATTTCCTTTAGGGAAGAACTGTGCCTCCACGTTT
AACTCTGACAGCGGCACCCCGGGCCTAGCAGCCAGTGTCTTAGTCGTGAGTCATGGCGCC
TACATACGAAGCCTGTTGGATTACTTTCTGACTGACCTCAAGTGCTCGTTCCCAGCGACT
CTGAGCAGGTCCGAGCTCACGTCAGTCAGCCCTAACACAGGGATGACTGTCTTCATCCTA
AACTTTGAGAAAGGAGGCAAAGGGAGACCAACTGCCCAGTGTGTGTGTGTGAACCTCCAG
GGCCACCTGGCCGGGGTGAACAAAACTCCCTAA
Enzyme 11 GenBank Gene ID BC116101 Link Image
Enzyme 11 GeneCard ID TIGAR Link Image
Enzyme 11 GenAtlas ID Not Available
Enzyme 11 HGNC ID Not Available
Enzyme 11 Chromosome Location Not Available
Enzyme 11 Locus Not Available
Enzyme 11 SNPs SNPJam Report Link Image
Enzyme 11 General References Not Available
Enzyme 11 Metabolite References Not Available