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Bovine Metabolome Database



Showing metabocard for Tetrahydrobiopterin (BMDB00027)

Legend: metabolite field enzyme field

Version 1.0
Creation Date 2005-11-16 15:48:42
Update Date 2009-05-05 20:57:38
Accession Number BMDB00027
Common Name Tetrahydrobiopterin
Description Tetrahydrobiopterin or BH4 is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase. A defect in BH4 production and/or a defect in the enzyme dihydropteridine reductase (DHPR) causes phenylketonuria type IV, as well as dopa-responsive dystonias. -- Wikipedia.
Synonyms
  1. (1R,2S)-(2-Amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)-1,2-propandiol
  2. 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-5,6,7,8-Tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone
  3. 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-Pteridinone
  4. 5,6,7,8-Tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone
  5. 5,6,7,8-Tetrahydrobiopterin
  6. 5,6,7,8-erythro-tetrahydrobiopterin
  7. 5,6,7,8-tetra-H-biopterin
  8. L-erythro-2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinon
  9. Tetrahydrobiopterin
  10. tetra-H-biopterin
  11. tetra-hydro-biopterin
Chemical IUPAC Name 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-1H-pteridin-4-one
Chemical Formula C9H15N5O3
Chemical Structure Structure
Chemical Taxonomy
Kingdom
  • Organic
Super Class
  • Heterocyclic molecules
Class
  • Pterins
Sub Class
  • Dihydro-pterins
Family
  • Mammalian_Metabolite
Species
  • secondary alcohol; 1,2-diol; 1,2-aminoalcohol; primary amine; primary aromatic amine; secondary amine; secondary aliphatic/aromatic amine (alkylarylamine); oxo(het)arene; aromatic compound; heterocyclic compound
Biofunction
  • Enzyme co-factor; Component of Phenylalanine, tyrosine and tryptophan biosynthesis; Component of Tryptophan metabolism; Component of Tyrosine metabolism
Application
Source
  • Endogenous
Average Molecular Weight 241.247
Monoisotopic Molecular Weight 241.117493
Isomeric SMILES CC(O)C(O)C1CNC2=C(N1)C(=O)NC(N)=N2
Canonical SMILES CC(O)C(O)C1CNC2=C(N1)C(=O)NC(N)=N2
KEGG Compound ID C00272 Link Image
BioCyc ID TETRA-H-BIOPTERIN Link Image
BiGG ID 34464 Link Image
Wikipedia Link Tetrahydrobiopterin Link Image
METLIN ID 5098 Link Image
PubChem Compound 1125 Link Image
PubChem Substance 3570 Link Image
ChEBI ID 15372 Link Image
CAS Registry Number 17528-72-2
InChI Identifier InChI=1/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)
Synthesis Reference He, Aimin. The function and biosynthesis of tetrahydrobiopterin in nocardia. (2002), 123 pp.
Melting Point (Experimental) 250-255 oC (hydrochloride salt)
Experimental Water Solubility Not Available Source: PhysProp
Predicted Water Solubility 2.03 mg/mL [Predicted by ALOGPS] Calculated using ALOGPS
Physiological Charge 0
State Solid
Experimental LogP/Hydrophobicity Not Available Source: PhysProp
Predicted LogP/Hydrophobicity -1.82 [Predicted by ALOGPS]; -1.7 [Predicted by PubChem via XLOGP] Calculated using ALOGPS
Material Safety Data Sheet (MSDS)
MOL File Show
SDF File Show
PDB File Show
2D Structure
3D Structure
Experimental PDB ID 1DF1 Link Image
Experimental PDB File Show
Experimental PDB Structure
Experimental 1H NMR Spectrum Not Available
Experimental 13C NMR Spectrum Not Available
Experimental 13C HSQC Spectrum Not Available
Predicted 1H NMR Spectrum Show Image
Show Peaklist
Predicted 13C NMR Spectrum Show Image
Show Peaklist
Mass Spectrum Not Available
Simplified TOCSY Spectrum Not Available
BMRB Spectrum Not Available
Cellular Location
  • Cytoplasm (Predicted from LogP)
  • nucleus
Biofluid Location Not Available
Tissue Location
Tissue References
All Tissues
Concentrations (Normal) Not Available
Concentrations (Abnormal) Not Available
Pathway Names
  • Folate and Pterine Biosynthesis
HMDB Pathways
Name Folate and Pterine Biosynthesis
Image Show Link Image
KEGG Pathways
Name Folate and Pterine Biosynthesis
Image Show Link Image
SimCell Pathways
Name Folate and Pterine Biosynthesis
Image Show Link Image
Graph
SBML
General References
  1. Wikipedia Link Image
Metabolic Enzymes
  1. Nitric oxide synthase, endothelial
  2. Nitric oxide synthase, inducible
  3. Sepiapterin reductase
  4. Tyrosine 3-monooxygenase
  5. Phenylalanine-4-hydroxylase
  6. Inducible nitric oxid synthase
Enzyme 1 [top]
Enzyme 1 ID 22
Enzyme 1 Name Nitric oxide synthase, endothelial
Enzyme 1 Synonyms
  1. Endothelial NOS
  2. eNOS
  3. EC-NOS
  4. NOS type III
  5. NOSIII
  6. Constitutive NOS
  7. cNOS
Enzyme 1 Gene Name NOS3
Enzyme 1 Protein Sequence >Nitric oxide synthase, endothelial
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSRAPAPATPHAPDHSPAPNSPT
LTRPPEGPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRCCLGSLVLPRKLQTRPSPGPP
PAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAW
RNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGR
GDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDE
APELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYM
STEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIV
DHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPD
PWKGSATKGAGITRKKTFKEVANAVKISASLMGTLMAKRVKATILYASETGRAQSYAQQL
GRLFRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYN
SSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP
HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAKAAFQASCETFCVGEEAKA
AAQDIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRAT
ILVRLDTAGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPTESVAVEQLEKGSPG
GPPPSWVRDPRLPPCTLRQALTFFLDITSPPSPRLLRLLSTLAEEPSEQQELETLSQDPR
RYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPNAHPGEVHLTVA
VLAYRTQDGLGPLHYGVCSTWLSQLKTGDPVPCFIRGAPSFRLPPDPYVPCILVGPGTGI
APFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQERGVFGRVLTAFS
REPDSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDME
LDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGP
DTPGP
Enzyme 1 Number of Residues 1205
Enzyme 1 Molecular Weight 133285.5
Enzyme 1 Theoretical pI 6.92
Enzyme 1 GO Classification
Function
Process
Component
Enzyme 1 General Function Inorganic ion transport and metabolism
Enzyme 1 Specific Function Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets
Enzyme 1 Pathways Not Available
Enzyme 1 Reactions Not Available
Enzyme 1 Pfam Domain Function
Enzyme 1 Signals
  • None
Enzyme 1 Transmembrane Regions
  • None
Enzyme 1 Essentiality Not Available
Enzyme 1 GenBank ID Protein 163422 Link Image
Enzyme 1 UniProtKB/Swiss-Prot ID P29473 Link Image
Enzyme 1 UniProtKB/Swiss-Prot Entry Name NOS3_BOVIN Link Image
Enzyme 1 PDB ID 1FOL Link Image
Enzyme 1 PDB File Show
Enzyme 1 3D Structure
Enzyme 1 Cellular Location Not Available
Enzyme 1 Gene Sequence >3618 bp
ATGGGCAACTTGAAGAGTGTGGGCCAGGAGCCCGGGCCCCCCTGCGGCCTGGGGCTGGGG
CTGGGCCTCGGGCTATGCGGCAAGCAGGGCCCAGCCTCCCCGGCACCTGAGCCCAGCCGG
GCCCCCGCACCCGCCACCCCGCACGCGCCAGACCACAGCCCAGCTCCCAACAGCCCCACG
CTGACCCGGCCTCCGGAGGGGCCCAAGTTCCCTCGCGTGAAGAACTGGGAGCTGGGGAGC
ATCACCTACGACACTCTGTGCGCGCAGTCCCAACAGGACGGGCCCTGCACTCCCAGGTGC
TGCCTGGGCTCCCTGGTGTTGCCCCGGAAACTGCAGACCCGGCCCTCCCCGGGACCTCCA
CCCGCTGAGCAGCTGCTGAGCCAGGCCAGGGACTTCATCAACCAGTACTACAGCTCCATC
AAGAGGAGCGGCTCCCAGGCTCACGAGGAGCGGCTTCAGGAGGTGGAGGCCGAGGTGGCA
TCCACGGGCACCTACCACCTCCGAGAGAGCGAGCTGGTGTTCGGGGCCAAGCAGGCCTGG
CGCAACGCACCCCGCTGCGTGGGCCGCATCCAGTGGGGGAAGCTGCAGGTGTTTGATGCC
CGGGACTGCAGCTCAGCACAGGAGATGTTCACCTACATCTGCAACCACATCAAGTACGCC
ACCAACCGCGGCAACCTTCGCTCGGCCATCACAGTGTTCCCGCAGCGCGCCCCGGGCCGC
GGAGACTTCCGGATCTGGAACAGCCAGCTGGTGCGCTACGCAGGCTACAGACAGCAGGAT
GGCTCTGTGCGTGGGGACCCAGCCAATGTGGAGATCACGGAGCTCTGCATCCAGCACGGC
TGGACCCCCGGAAACGGCCGCTTCGACGTGCTGCCCCTGCTGCTCCAGGCCCCAGACGAG
GCTCCAGAGCTCTTTGTTCTGCCCCCCGAGCTGGTCCTTGAAGTGCCCCTGGAGCACCCC
ACACTGGAGTGGTTCGCGGCCCTGGGCCTGCGATGGTATGCCCTCCCGGCCGTGTCCAAC
ATGCTGCTGGAAATCGGGGGTCTGGAGTTCTCCGCGGCCCCCTTCAGCGGCTGGTACATG
AGCACGGAGATTGGCACGCGGAACCTGTGTGACCCTCACCGCTACAATATCCTGGAGGAT
GTGGCCGTCTGCATGGACCTCGACACGCGGACCACCTCGTCCCTGTGGAAGGACAAGGCG
GCCGTGGAGATCAACCTGGCTGTGCTGCACAGCTTTCAGCTCGCCAAGGTGACCATCGTG
GACCACCACGCCGCCACGGTGTCCTTCATGAAGCACCTGGACAACGAGCAGAAGGCCAGG
GGGGGCTGCCCCGCCGACTGGGCCTGGATCGTGCCCCCCATCTCAGGCAGCCTCACGCCC
GTCTTCCACCAGGAGATGGTCAACTACATCCTGTCCCCTGCCTTCCGCTACCAGCCAGAC
CCCTGGAAAGGGAGCGCGACCAAGGGCGCAGGCATCACCAGGAAGAAGACCTTTAAGGAA
GTGGCCAACGCGGTGAAGATCTCTGCCTCACTCATGGGCACCCTGATGGCCAAGCGAGTG
AAAGCAACCATCCTGTACGCCTCTGAGACCGGCCGGGCCCAGAGCTACGCTCAGCAGCTG
GGGAGGCTCTTCCGGAAGGCCTTCGATCCCCGGGTCCTGTGCATGGATGAGTATGACGTG
GTGTCCCTGGAGCACGAGGCGCTGGTACTGGTGGTGACCAGCACCTTTGGGAATGGCGAT
CCCCCGGAGAATGGAGAGAGTTTTGCAGCTGCCCTGATGGAGATGTCGGGGCCCTACAAC
AGCTCCCCGCGGCCGGAACAGCACAAGAGTTACAAGATCCGCTTCAACAGCGTCTCCTGC
TCAGACCCGCTGGTGTCCTCCTGGCGGCGGAAGAGAAAGGAGTCCAGCAACACAGACAGT
GCGGGGGCCCTGGGGACCCTCAGGTTCTGTGTGTTCGGACTGGGCTCCCGGGCATACCCC
CACTTCTGCGCCTTCGCGCGAGCGGTGGACACCCGGCTGGAAGAGCTTGGAGGGGAGCGG
CTGCTGCAGCTGGGCCAGGGCGATGAGCTCTGCGGCCAGGAAGAGGCCTTCCGTGGTTGG
GCAAAGGCGGCCTTCCAGGCCTCCTGTGAGACCTTCTGCGTTGGGGAGGAGGCCAAGGCC
GCCGCCCAGGACATCTTCAGCCCCAAACGGAGCTGGAAACGCCAGAGGTACCGGCTGAGC
ACCCAGGCCGAGGGCCTCCAGCTGCTGCCAGGCCTGATCCACGTGCACAGACGGAAGATG
TTTCAGGCCACAGTCCTCTCGGTGGAAAATCTGCAAAGCAGCAAGTCCACCCGGGCCACC
ATCCTGGTGCGCCTGGACACTGCAGGCCAGGAGGGGCTGCAGTACCAGCCGGGGGACCAC
ATAGGCATCTGCCCGCCCAACCGGCCGGGCCTGGTGGAGGCGCTGCTGAGCCGCGTGGAG
GACCCGCCACCGCCCACCGAGTCTGTGGCTGTGGAGCAGCTGGAGAAAGGCAGCCCAGGC
GGCCCTCCTCCCAGCTGGGTGCGGGACCCACGGCTGCCCCCGTGCACGCTGCGCCAGGCT
CTCACCTTCTTCCTGGACATCACCTCCCCACCCAGCCCCCGGCTTCTCCGACTGCTCAGC
ACCCTGGCCGAAGAACCCAGCGAGCAGCAGGAGCTTGAGACCCTCAGTCAGGACCCCCGG
CGCTACGAGGAGTGGAAGTGGTTCCGCTGCCCCACGCTGCTGGAGGTGCTGGAGCAGTTC
CCGTCCGTGGCGCTGCCCGCCCCGCTGCTCCTCACCCAGCTGCCCCTGCTGCAGCCCCGG
TACTACTCTGTCAGCTCGGCCCCCAACGCCCACCCCGGAGAGGTCCACCTCACAGTGGCC
GTGCTGGCGTACAGGACCCAAGATGGGCTGGGCCCCCTACACTACGGGGTCTGCTCCACA
TGGCTGAGCCAGCTCAAGACTGGAGACCCCGTGCCCTGCTTCATCAGGGGGGCTCCCTCC
TTCCGGCTGCCGCCTGACCCCTACGTGCCCTGCATCCTCGTGGGCCCTGGCACTGGCATC
GCCCCCTTCCGGGGATTTTGGCAGGAGAGGCTGCATGACATTGAGAGCAAAGGGCTGCAG
CCCGCCCCCATGACCCTGGTGTTCGGCTGCCGCTGCTCCCAACTCGACCATCTCTACCGC
GACGAGGTGCAGGACGCCCAGGAGCGCGGGGTGTTTGGCCGCGTCCTCACCGCCTTCTCC
CGGGAACCTGACAGCCCCAAGACCTACGTACAGGACATCCTGAGAACCGAGCTGGCTGCC
GAGGTGCACCGCGTGCTGTGCCTCGAGCGGGGCCACATGTTTGTCTGCGGCGATGTCACT
ATGGCAACCAGCGTCCTGCAGACGGTGCAGCGCATCTTGGCGACAGAGGGCGACATGGAG
CTGGACGAGGCGGGCGACGTCATCGGCGTGCTGCGGGATCAGCAACGCTATCACGAGGAC
ATTTTCGGCCTCACGCTGCGCACCCAGGAGGTGACAAGCCGTATACGTACCCAGAGCTTT
TCCCTGCAGGAGCGGCATCTGCGGGGCGCGGTGCCCTGGGCCTTCGACCCGCCCGGCCCA
GACACCCCCGGCCCCTGA
Enzyme 1 GenBank Gene ID M99057 Link Image
Enzyme 1 GeneCard ID NOS3 Link Image
Enzyme 1 GenAtlas ID Not Available
Enzyme 1 HGNC ID Not Available
Enzyme 1 Chromosome Location Chromosome:7
Enzyme 1 Locus 7q36
Enzyme 1 SNPs SNPJam Report Link Image
Enzyme 1 General References
  1. [PubMed Link Image]
Enzyme 1 Metabolite References Not Available
Enzyme 2 [top]
Enzyme 2 ID 69
Enzyme 2 Name Nitric oxide synthase, inducible
Enzyme 2 Synonyms
  1. Inducible NO synthase
  2. Inducible NOS
  3. iNOS
  4. NOS type II
  5. NOSII
Enzyme 2 Gene Name NOS2
Enzyme 2 Protein Sequence >Nitric oxide synthase, inducible
MACPWQFLFKIKSQKVDLATELDINNNVGKFYQPPSSPVTQDDPKRHSPGKHGNESPQPL
TGTVKTSPESLSKLDAPPSACPRHVRIKNWGSGVTFQDTLHQKAKGDLSCKSKSCLASIM
NPKSLTIGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ
LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYATNNGNI
RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG
RFDVLPLVLQADGRDPELFEIPPDLVLEVPMEHPRYEWFRELELKWYALPAVANMLLEVG
GLEFPGCPFNGWYMGTEVGVRDFCDAQRYNILEEVGRRMGLETHKVASLWKDRAVVEINV
AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM
LNYVLSPFYYYQVEPWKTHVWQDERRRPQRREIRFKVLVKAVFFASVLMHKAMASRVRAT
ILFATETGRSETLAQDLGALFSCAFNPKVLCMDQYQLSHLEEEQLLLVVTSTFGNGDSPG
NGEKLKKSLLMLKELTNTFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQLAPTGEGD
ELSGQEEAFRSWAVQTFKAACETFDVSGKHHIEIPKLYTSNVTWDPQHYRLVQDSEPLDL
NKALSSMHAKHVFTMRLKSQQNLQSPKSSRTTLLVELSCEGSQAPSYLPGEHLGVFPCNQ
PALVQGILERVVDGPAPHQPVRLETLCENGSYWVKDKRLPPCSLSQALTYFLDITTPPTQ
LLLRKLAQLATEEAEKQRLETLCQPSDYNKWKFTNSPTFLEVLEEFPSLRVSASFLLSQL
PILKPRYYSISSSRDLTPTEIHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCF
VRSASGFQLPEDRSRPCILIGPGTGIAPFRSFWQQRLHEAEHKGLQGGRMTLVFGCRRPE
EDHLYWEEMLEMARKGVLHEVHTAYSRLPDQPKVYVQDILRQRLAGEVLRVLHEEQGHLY
VCGDVRMARDVARTLKQLMATALSLNEEQVEDYFFQLKNQKRYHEDIFGAVFPYEVKKDG
AAGLPSNPRAPGAHRS
Enzyme 2 Number of Residues 1156
Enzyme 2 Molecular Weight 131206.8
Enzyme 2 Theoretical pI 7.42
Enzyme 2 GO Classification
Function
Process
Component
Enzyme 2 General Function Inorganic ion transport and metabolism
Enzyme 2 Specific Function Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions
Enzyme 2 Pathways Not Available
Enzyme 2 Reactions Not Available
Enzyme 2 Pfam Domain Function
Enzyme 2 Signals
  • None
Enzyme 2 Transmembrane Regions
  • None
Enzyme 2 Essentiality Not Available
Enzyme 2 GenBank ID Protein 110468061 Link Image
Enzyme 2 UniProtKB/Swiss-Prot ID Q27995 Link Image
Enzyme 2 UniProtKB/Swiss-Prot Entry Name NOS2_BOVIN Link Image
Enzyme 2 PDB ID 2NSI Link Image
Enzyme 2 PDB File Show
Enzyme 2 3D Structure
Enzyme 2 Cellular Location Not Available
Enzyme 2 Gene Sequence >3471 bp
ATGGCCTGTCCCTGGCAGTTTCTGTTCAAAATCAAATCCCAAAAGGTGGACTTGGCTACG
GAACTGGACATCAACAACAATGTGGGAAAATTCTACCAGCCCCCGTCCAGTCCAGTGACA
CAGGATGACCCCAAACGTCACAGCCCGGGCAAGCACGGGAATGAGTCTCCCCAGCCCCTC
ACGGGGACAGTAAAGACGTCTCCAGAATCCCTGAGCAAGCTGGACGCGCCCCCGTCAGCC
TGTCCACGGCATGTGAGGATCAAAAACTGGGGCAGCGGAGTGACTTTCCAAGACACGCTT
CACCAGAAGGCCAAAGGGGATCTCTCTTGCAAGTCCAAGTCTTGCCTGGCATCCATCATG
AACCCCAAAAGTTTGACCATAGGACCCCGGGACAAGCCAACCCCCCCAGACGAGCTTCTA
CCTCAAGCTATCGAATTTGTCAACCAGTATTACGGCTCCTTCAAAGAGGCAAAAATAGAG
GAACATCTGGCCAGGGTGGAAGCAGTAACAAAGGAGATAGAAACAACAGGAACCTACCAG
CTGACGGGAGATGAGCTCATCTTCGCCACCAAGCAGGCCTGGCGCAACGCCCCCCGCTGC
ATCGGAAGGATCCAGTGGTCGAACCTGCAGGTCTTTGACGCCCGGAGCTGTTCCACGGCC
CAGGAAATGTTCGAACACATCTGCAGACACGTGCGTTATGCCACCAACAACGGCAACATC
AGGTCGGCCATCACTGTGTTCCCCCAGCGGAGCGATGGGAAGCATGACTTCCGGGTCTGG
AACGCCCAGCTCATCCGCTATGCCGGCTACCAGATGCCAGATGGCAGCATCAGAGGGGAC
CCCGCCAACGTGGAGTTCACACAGCTGTGCATCGACCTGGGCTGGAAGCCCAAGTACGGC
CGCTTCGACGTGTTGCCTCTAGTCCTGCAGGCTGACGGCCGTGACCCAGAGCTCTTCGAA
ATCCCCCCTGACCTTGTTCTCGAGGTGCCCATGGAACATCCCAGGTACGAATGGTTCCGG
GAGCTGGAGCTCAAGTGGTACGCCCTGCCAGCCGTGGCCAACATGCTGCTTGAGGTGGGC
GGCCTCGAGTTCCCAGGGTGCCCCTTCAACGGGTGGTACATGGGCACAGAAGTTGGAGTC
CGGGACTTCTGCGACGCCCAGCGATACAACATCCTGGAGGAAGTGGGCAGAAGGATGGGC
CTGGAAACGCACAAGGTGGCCTCACTCTGGAAGGACCGGGCTGTCGTTGAGATCAACGTC
GCTGTGCTCCACAGTTTCCAGAAGCAGAACGTGACCATCATGGACCACCACTCCGCTGCA
GAGTCCTTCATGAAGTACATGCAGAATGAGTACCGCTCCCGAGGGGGCTGCCCAGCTGAC
TGGATTTGGCTGGTCCCCCCGATCTCTGGAAGCATCACCCCCGTGTTCCACCAGGAGATG
TTAAATTACGTCCTGTCCCCTTTCTACTACTACCAGGTGGAGCCCTGGAAAACCCACGTC
TGGCAGGACGAGAGGCGGAGACCCCAGAGAAGAGAAATTCGATTCAAAGTCTTGGTCAAA
GCCGTGTTCTTCGCCTCGGTGCTGATGCATAAGGCCATGGCATCCCGGGTCAGAGCCACG
ATCCTCTTTGCAACAGAGACGGGGAGATCGGAAACGCTGGCCCAGGACCTGGGGGCTTTG
TTCAGCTGTGCCTTCAACCCCAAGGTTCTCTGCATGGATCAGTACCAGCTGAGCCATCTG
GAGGAGGARCAGCTGCTGCTGGTGGTGACCAGCACTTTTGGCAACGGAGACTCCCCTGGC
AACGGAGAGAAACTGAAGAAGTCCCTCTTGATGCTGAAAGAACTCACCAACACGTTCCGG
TACGCCGTGTTTGGCCTTGGCTCCAGCATGTACCCTCAGTTCTGCGCTTTTGCTCATGAC
ATTGACCAGAAGTTGTCCCAGCTGGGGGCTTCTCAGCTTGCCCCAACCGGGGAAGGGGAC
GAACTCAGCGGGCAGGAGGAGGCCTTTCGCAGCTGGGCCGTGCAAACCTTCAAGGCAGCC
TGTGAGACATTCGATGTCAGCGGCAAGCACCACATTGAGATCCCCAAGCTCTACACTTCC
AATGTGACCTGGGACCCGCAGCACTACAGGCTCGTGCAGGACTCAGAGCCTCTGGACCTC
AACAAAGCCCTGAGCAGTATGCACGCCAAGCATGTGTTCACCATGAGGCTCAAATCGCAG
CAGAATCTGCAGAGTCCGAAATCCAGCCGCACCACCCTCCTGGTGGAACTCTCCTGTGAG
GGCAGCCAAGCTCCAAGCTACCTGCCGGGAGAGCACCTCGGAGTTTTCCCATGCAACCAG
CCGGCCCTGGTTCAAGGCATCCTTGAGCGAGTGGTGGATGGCCCTGCCCCGCACCAGCCT
GTGCGCCTGGAGACCCTCTGTGAGAATGGCAGCTATTGGGTCAAGGATAAGCGGCTGCCA
CCTTGCTCACTCAGCCAGGCTCTCACCTATTTCCTGGACATCACCACCCCGCCAACCCAG
CTGCTGCTCCGAAAGCTGGCCCAGCTGGCCACAGAAGAGGCTGAGAAGCAGAGGCTGGAG
ACCCTATGCCAGCCCTCAGATTACAACAAGTGGAAGTTCACCAACAGCCCCACATTTCTG
GAGGTGCTGGAGGAGTTCCCGTCCCTGCGGGTGTCTGCCAGCTTCCTGCTCTCCCAGCTC
CCTATTCTGAAGCCCCGGTACTACTCCATCAGCTCCTCCAGGGACCTCACACCCACGGAG
ATCCACCTCACTGTGGCCGTGCTCACGTACCGCACCCGAGATGGCCAAGGTCCCCTGCAC
CATGGTGTCTGCAGCACGTGGCTCAGCAGCTTGAAGCCCCAAGACCCGGTGCCCTGCTTT
GTGCGAAGTGCCAGYGGCTTCCAGCTTCCCGAGGACCGCTCCCGTCCTTGCATCCTCATT
GGGCCCGGCACGGGCATCGCCCCCTTCCGCAGTTTCTGGCAGCAGCGGCTCCATGAGGCT
GAGCACAAAGGGCTCCAGGGCGGCCGCATGACCCTGGTTTTCGGGTGCCGCCGCCCAGAA
GAGGACCACCTCTACTGGGAGGAGATGCTGGAGATGGCCCGCAAGGGGGTGCTGCACGAG
GTGCACACCGCCTATTCCCGCCTGCCTGACCAGCCCAAGGTCTATGTTCAAGACATCCTG
CGGCAGCGGCTGGCGGGCGAGGTGCTTCGCGTGCTCCATGAGGAGCAAGGTCACCTCTAT
GTCTGTGGGGATGTGCGCATGGCCCGGGACGTGGCCCGCACCCTGAAGCAGCTGATGGCT
ACTGCGCTGAGCCTGAACGAGGAACAGGTGGAGGACTATTTCTTCCAGCTCAAGAACCAG
AAGCGCTATCATGAAGACATCTTTGGTGCTGTATTTCCCTATGAGGTGAAAAAGGATGGG
GCAGCAGGGCTGCCCAGCAATCCCAGAGCTCCAGGCGCCCACAGAAGTTAA
Enzyme 2 GenBank Gene ID DQ676956 Link Image
Enzyme 2 GeneCard ID NOS2 Link Image
Enzyme 2 GenAtlas ID Not Available
Enzyme 2 HGNC ID Not Available
Enzyme 2 Chromosome Location Chromosome:1
Enzyme 2 Locus 17q11.2-q12
Enzyme 2 SNPs SNPJam Report Link Image
Enzyme 2 General References
  1. [PubMed Link Image]
Enzyme 2 Metabolite References Not Available
Enzyme 3 [top]
Enzyme 3 ID 379
Enzyme 3 Name Sepiapterin reductase
Enzyme 3 Synonyms
  1. SPR
Enzyme 3 Gene Name SPR
Enzyme 3 Protein Sequence >Sepiapterin reductase
MEGSVGKVGGLGRTLCVLTGASRGFGRTLAQVLAPLMSPRSVLVLSARNDEALRQLETEL
GAEWPGLRIVRVPADLGAETGLQQLVGALCDLPRPEGLQRVLLINNAGTLGDVSKRWVDL
TDPTEVNNYWTLNLTSTLCLTSSILQAFPDSPGLSRTVVNISSICALQPFKGWGLYCAGK
AARNMMFQVLAAEEPSVRVLSYGPGPLDTDMQQLARETSVDPDLRKSLQELKRKGELVDC
KISAQKLLSLLQNDKFESGAHIDFYDE
Enzyme 3 Number of Residues 267
Enzyme 3 Molecular Weight 28938.9
Enzyme 3 Theoretical pI 5.15
Enzyme 3 GO Classification
Function
Process
Component
Enzyme 3 General Function Lipid transport and metabolism
Enzyme 3 Specific Function Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin
Enzyme 3 Pathways Not Available
Enzyme 3 Reactions Not Available
Enzyme 3 Pfam Domain Function
Enzyme 3 Signals
  • None
Enzyme 3 Transmembrane Regions
  • None
Enzyme 3 Essentiality Not Available
Enzyme 3 GenBank ID Protein 114797046 Link Image
Enzyme 3 UniProtKB/Swiss-Prot ID Q17QK8 Link Image
Enzyme 3 UniProtKB/Swiss-Prot Entry Name SPRE_BOVIN Link Image
Enzyme 3 PDB ID Not Available
Enzyme 3 Cellular Location Not Available
Enzyme 3 Gene Sequence >804 bp
ATGGAGGGCAGCGTCGGCAAGGTGGGCGGCCTGGGGCGCACCTTATGCGTGCTGACTGGG
GCTTCCCGGGGCTTCGGACGGACGCTGGCCCAAGTCCTGGCCCCGCTGATGTCGCCTCGC
TCCGTGCTGGTCCTAAGCGCCCGCAATGACGAGGCCCTGCGGCAGCTGGAGACCGAGCTG
GGCGCCGAGTGGCCGGGTCTGCGTATCGTGCGGGTGCCCGCCGACCTGGGCGCCGAGACC
GGCTTGCAGCAACTGGTCGGTGCTCTGTGCGACCTCCCCAGGCCCGAGGGCCTGCAGCGA
GTGCTGCTCATCAACAATGCGGGCACTCTTGGAGATGTATCCAAACGTTGGGTGGACCTG
ACTGACCCAACTGAAGTGAACAACTACTGGACTCTGAACTTGACTTCCACGCTCTGCCTG
ACTTCCAGTATCCTGCAGGCCTTCCCGGACAGTCCTGGCCTCAGCAGGACTGTGGTTAAC
ATCTCGTCCATCTGTGCCCTGCAGCCCTTCAAGGGCTGGGGACTGTACTGTGCTGGGAAG
GCTGCCCGTAACATGATGTTCCAGGTCCTGGCGGCGGAGGAACCTAGCGTGAGGGTGCTG
AGCTATGGCCCAGGTCCCCTGGACACTGACATGCAGCAGTTAGCCCGGGAGACCTCTGTG
GACCCAGACTTGCGAAAAAGCCTGCAGGAGCTGAAGAGAAAGGGGCAACTTGTGGATTGC
AAGATATCAGCCCAGAAACTTCTGAGCTTGCTGCAAAATGACAAGTTCGAGTCTGGAGCC
CATATTGACTTCTACGATGAATAA
Enzyme 3 GenBank Gene ID DQ978331 Link Image
Enzyme 3 GeneCard ID SPR Link Image
Enzyme 3 GenAtlas ID Not Available
Enzyme 3 HGNC ID Not Available
Enzyme 3 Chromosome Location Chromosome:2
Enzyme 3 Locus 2p14-p12
Enzyme 3 SNPs SNPJam Report Link Image
Enzyme 3 General References Not Available
Enzyme 3 Metabolite References Not Available
Enzyme 4 [top]
Enzyme 4 ID 388
Enzyme 4 Name Tyrosine 3-monooxygenase
Enzyme 4 Synonyms
  1. Tyrosine 3-hydroxylase
  2. TH
Enzyme 4 Gene Name TH
Enzyme 4 Protein Sequence >Tyrosine 3-monooxygenase
MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIQDARKEREKAEAAASSSE
SAEAAAWLERDGEAVLTLLFALPPTRPPALTRAIKVFETFEAHLHHLETRPAQPLRAGSP
PLECFVRCEVPGPVVPALLSALRRVAEDVRAAGESKVLWFPRKVSELDKCHHLVTKFDPD
LDLDHPGFSDQAYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYSTLRGLYPTH
ACREHLEAFELLERFCGYREDRIPQLEDVSRFLKERTGFQLRPAAGLLSARDFLASLAFR
VFQCTQYIRHASSPMHSPEPECCHELLGHVPMLADRTFAQFSQDIGLASLGVSDEEIEKL
STLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQT
YQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIRHALDGVQDEM
QALAHALNAIS
Enzyme 4 Number of Residues 491
Enzyme 4 Molecular Weight 55122.8
Enzyme 4 Theoretical pI 5.96
Enzyme 4 GO Classification
Function
Process
Component
Enzyme 4 General Function Amino acid transport and metabolism
Enzyme 4 Specific Function Plays an important role in the physiology of adrenergic neurons
Enzyme 4 Pathways
  • Catecholamine biosynthesis
  • dopamine biosynthesis
  • dopamine from L-tyrosine:step 1/2
Enzyme 4 Reactions Not Available
Enzyme 4 Pfam Domain Function
Enzyme 4 Signals
  • None
Enzyme 4 Transmembrane Regions
  • None
Enzyme 4 Essentiality Not Available
Enzyme 4 GenBank ID Protein 163751 Link Image
Enzyme 4 UniProtKB/Swiss-Prot ID P17289 Link Image
Enzyme 4 UniProtKB/Swiss-Prot Entry Name TY3H_BOVIN Link Image
Enzyme 4 PDB ID 1TOH Link Image
Enzyme 4 PDB File Show
Enzyme 4 3D Structure
Enzyme 4 Cellular Location Not Available
Enzyme 4 Gene Sequence >1476 bp
ATGCCTACCCCCAACGCCGCCTCGCCGCAGGCCAAGGGCTTCCGCAGGGCCGTCTCCGAG
CTGGACGCCAAGCAGGCTGAGGCCATCATGTCCCCACGCTTCGTCGGGAGGCGGCAGAGC
CTCATCCAGGACGCACGCAAGGAGCGGGAGAAGGCGGAGGCCGCGGCCTCATCCTCGGAG
TCCGCGGAGGCGGCAGCCTGGTTGGAGAGGGACGGGGAGGCGGTGCTGACCCTGCTGTTC
GCCCTGCCGCCCACCAGGCCCCCTGCGCTGACCCGGGCTATCAAGGTGTTTGAGACATTC
GAAGCCCACCTCCACCACCTGGAGACCCGACCGGCCCAGCCACTGCGGGCGGGGAGCCCG
CCCCTGGAGTGCTTCGTGCGCTGTGAGGTGCCCGGCCCAGTGGTGCCCGCCCTGCTGAGC
GCCCTGCGCCGCGTGGCAGAAGATGTGCGTGCCGCCGGGGAGAGCAAAGTCCTCTGGTTC
CCAAGGAAAGTGTCCGAGCTGGACAAGTGTCACCACCTCGTCACCAAGTTTGACCCTGAC
CTGGACTTGGATCATCCCGGCTTCTCCGACCAGGCGTACCGCCAGCGCAGGAAGCTGATC
GCCGAGATCGCCTTCCAGTACAAGCAAGGCGACCCCATTCCCCACGTGGAGTACACAGCC
GAGGAGACAGCCACCTGGAAGGAGGTCTACTCCACGCTGCGGGGCCTGTACCCCACCCAC
GCCTGCCGCGAGCACCTGGAGGCCTTCGAGCTGCTGGAGCGCTTCTGCGGGTACCGCGAG
GACCGAATCCCGCAGCTGGAGGACGTCTCACGCTTCCTGAAGGAGAGGACCGGCTTCCAG
CTGCGGCCCGCGGCCGGCCTGCTGTCCGCGCGGGACTTCCTGGCCAGCCTGGCCTTCCGC
GTGTTCCAGTGCACCCAGTACATCCGCCACGCCTCCTCGCCCATGCACTCCCCGGAGCCG
GAGTGCTGCCACGAGCTGCTGGGGCACGTGCCCATGCTCGCCGACCGGACCTTCGCGCAG
TTTTCCCAGGACATCGGGCTCGCATCCTTGGGAGTGTCGGATGAGGAAATTGAGAAGCTG
TCCACGCTGTACTGGTTCACCGTGGAGTTCGGGCTATGCAAACAGAATGGAGAGGTGAAG
GCCTACGGCGCGGGGCTGCTGTCCTCCTACGGGGAGCTCCTGCACTCCCTTTCCGAGGAG
CCTGAGATCCGGGCCTTCGACCCTGATGCAGCGGCCGTGCAGCCCTATCAGGACCAGACC
TACCAGCCCGTCTACTTCGTGTCTGAGAGCTTCAGCGATGCCAAGGACAAGCTCAGGAGC
TACGCCTCCCGCATCCAGCGCCCCTTCTCTGTGAAGTTTGACCCGTACACACTGGCCATC
GACGTGCTGGACAGTCCCCACGCCATCCGGCACGCCCTGGACGGCGTCCAGGACGAGATG
CAGGCCCTGGCCCATGCTCTGAACGCCATCAGCTAG
Enzyme 4 GenBank Gene ID M36794 Link Image
Enzyme 4 GeneCard ID TH Link Image
Enzyme 4 GenAtlas ID Not Available
Enzyme 4 HGNC ID Not Available
Enzyme 4 Chromosome Location Chromosome:1
Enzyme 4 Locus 11p15.5
Enzyme 4 SNPs SNPJam Report Link Image
Enzyme 4 General References
  1. [PubMed Link Image]
Enzyme 4 Metabolite References Not Available
Enzyme 5 [top]
Enzyme 5 ID 389
Enzyme 5 Name Phenylalanine-4-hydroxylase
Enzyme 5 Synonyms
  1. PAH
  2. Phe-4-monooxygenase
Enzyme 5 Gene Name PAH
Enzyme 5 Protein Sequence >Phenylalanine-4-hydroxylase
MSALVLESRALGRKLSDFGQETSYIEGNSDQNAVSLIFSLKEEVGALARVLRLFEENDIN
LTHIESRPSRLRKDEYEFFTNLDQRSVPALANIIKILRHDIGATVHELSRDKKKDTVPWF
PRTIQELDNFANQVLSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYTE
EEKKTWGTVFRTLKSLYKTHACYEHNHIFPLLEKYCGFREDNIPQLEEVSQFLQSCTGFR
LRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQ
FSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSDK
PKLLPLELEKTAVQEYTITEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVHYDPYTQRI
EVLDNTQQLKILADSISSEVEILCSALQKLK
Enzyme 5 Number of Residues 451
Enzyme 5 Molecular Weight 51726.2
Enzyme 5 Theoretical pI 6.20
Enzyme 5 GO Classification
Function
Process
Component
Enzyme 5 General Function Amino acid transport and metabolism
Enzyme 5 Specific Function L-phenylalanine + tetrahydrobiopterin + O(2) = L-tyrosine + 4a-hydroxytetrahydrobiopterin
Enzyme 5 Pathways
  • Amino-acid degradation
  • L-phenylalanine degradation
  • acetoacetate and fumarate from L-phenylalanine:step 1/6
Enzyme 5 Reactions Not Available
Enzyme 5 Pfam Domain Function
Enzyme 5 Signals
  • None
Enzyme 5 Transmembrane Regions
  • None
Enzyme 5 Essentiality Not Available
Enzyme 5 GenBank ID Protein 146231900 Link Image
Enzyme 5 UniProtKB/Swiss-Prot ID Q2KIH7 Link Image
Enzyme 5 UniProtKB/Swiss-Prot Entry Name PH4H_BOVIN Link Image
Enzyme 5 PDB ID 2PHM Link Image
Enzyme 5 PDB File Show
Enzyme 5 3D Structure
Enzyme 5 Cellular Location Not Available
Enzyme 5 Gene Sequence >1356 bp
ATGTCAGCTCTGGTCCTGGAGAGCCGAGCCTTGGGCAGGAAACTCAGCGACTTTGGACAG
GAAACGAGCTATATTGAAGGCAACTCTGATCAAAATGCTGTATCGCTGATCTTCTCACTC
AAAGAAGAAGTTGGTGCACTGGCCAGAGTATTACGTTTATTTGAGGAGAATGATATAAAC
CTGACCCACATTGAATCAAGACCTTCACGTTTAAGGAAAGACGAGTATGAATTTTTCACC
AATCTGGATCAACGCAGCGTGCCTGCCCTGGCAAACATCATCAAGATCTTGAGACATGAC
ATTGGTGCCACTGTGCACGAGCTTTCCCGGGATAAGAAGAAAGACACAGTGCCCTGGTTT
CCAAGAACCATTCAGGAACTCGACAACTTTGCCAACCAGGTTCTCAGCTATGGAGCTGAA
CTGGATGCAGATCACCCGGGATTTAAAGATCCTGTATACCGAGCAAGACGGAAGCAATTC
GCTGACATTGCCTACAACTATAGACATGGGCAGCCCATTCCTCGAGTGGAATACACGGAG
GAAGAAAAAAAAACATGGGGGACGGTATTCAGGACCCTGAAGTCCTTGTATAAGACCCAT
GCTTGCTATGAGCACAACCACATTTTCCCCCTTCTGGAAAAGTATTGCGGCTTCCGTGAA
GATAACATTCCCCAGCTCGAAGAGGTTTCTCAGTTTCTGCAGAGTTGCACTGGTTTCCGC
CTCCGACCAGTCGCTGGCCTGCTTTCTTCTCGGGATTTCTTGGGTGGCCTGGCTTTCCGA
GTCTTCCACTGCACTCAGTACATCAGACATGGGTCTAAGCCCATGTATACACCAGAACCG
GACATATGCCATGAGCTCTTGGGACATGTACCTTTGTTTTCAGATCGCAGCTTTGCCCAG
TTTTCGCAGGAGATCGGCCTTGCCTCCCTGGGTGCACCTGATGAGTACATTGAAAAACTT
GCAACAATTTACTGGTTTACTGTGGAGTTTGGGCTCTGCAAGCAAGGAGACTCCATAAAG
GCATATGGTGCTGGGCTCCTGTCATCCTTTGGTGAATTACAGTATTGCCTATCAGACAAG
CCAAAGCTCCTTCCTCTGGAACTGGAGAAGACCGCTGTCCAGGAGTATACGATCACAGAG
TTCCAGCCTCTGTATTATGTGGCTGAGAGTTTTAATGATGCCAAGGAGAAAGTGAGGAAC
TTTGCTGCCACAATCCCACGGCCCTTCTCAGTTCATTATGACCCATACACTCAACGGATT
GAGGTCTTGGACAACACCCAGCAACTTAAGATTTTGGCTGACTCCATCAGTAGTGAAGTT
GAGATCCTTTGCAGTGCCCTCCAGAAATTAAAGTGA
Enzyme 5 GenBank Gene ID BT030585 Link Image
Enzyme 5 GeneCard ID PAH Link Image
Enzyme 5 GenAtlas ID Not Available
Enzyme 5 HGNC ID Not Available
Enzyme 5 Chromosome Location Chromosome:1
Enzyme 5 Locus 12q22-q24.2
Enzyme 5 SNPs SNPJam Report Link Image
Enzyme 5 General References
  1. [PubMed Link Image]
Enzyme 5 Metabolite References Not Available
Enzyme 6 [top]
Enzyme 6 ID 557
Enzyme 6 Name Inducible nitric oxid synthase
Enzyme 6 Synonyms Not Available
Enzyme 6 Gene Name iNOS
Enzyme 6 Protein Sequence >Inducible nitric oxid synthase
TYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYATNN
GNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPA
Enzyme 6 Number of Residues 105
Enzyme 6 Molecular Weight 12092.5
Enzyme 6 Theoretical pI 9.28
Enzyme 6 GO Classification
Function
Process
Component
Enzyme 6 General Function Involved in arginine binding
Enzyme 6 Specific Function Not Available
Enzyme 6 Pathways Not Available
Enzyme 6 Reactions Not Available
Enzyme 6 Pfam Domain Function
Enzyme 6 Signals
  • None
Enzyme 6 Transmembrane Regions
  • None
Enzyme 6 Essentiality Not Available
Enzyme 6 GenBank ID Protein 47057289 Link Image
Enzyme 6 UniProtKB/Swiss-Prot ID Q6ZXD5 Link Image
Enzyme 6 UniProtKB/Swiss-Prot Entry Name Q6ZXD5_BOVIN Link Image
Enzyme 6 PDB ID 4NOS Link Image
Enzyme 6 PDB File Show
Enzyme 6 3D Structure
Enzyme 6 Cellular Location Not Available
Enzyme 6 Gene Sequence Not Available
Enzyme 6 GenBank Gene ID AJ699400 Link Image
Enzyme 6 GeneCard ID iNOS Link Image
Enzyme 6 GenAtlas ID Not Available
Enzyme 6 HGNC ID Not Available
Enzyme 6 Chromosome Location Not Available
Enzyme 6 Locus Not Available
Enzyme 6 SNPs SNPJam Report Link Image
Enzyme 6 General References
  1. [PubMed Link Image]
Enzyme 6 Metabolite References Not Available